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Benhur Lee, MD, Pathology, New York, NY

BenhurLeeMD

Pathology • New York, NY

Blood Banking & Transfusion Medicine, Anatomic Pathology, Clinical Pathology

Professor of Microbiology, Icahn School of Medicine at Mount Sinai

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Summary

  • Professor Benhur Lee is a virologist with wide-ranging research interests who joined the Department of Microbiology at the Icahn School of Medicine at Mount Sinai (ISMMS) in 2014. He holds the Ward-Coleman Chair in Microbiology. Prior to his recruitment to Mount Sinai, Dr. Lee spent 12+ years as a member of the Department of Microbiology, Immunology & Molecular Genetics as well as the Department of Pathology and Laboratory Medicine at the David Geffen School of Medicine at UCLA (University of California, Los Angeles). He joined UCLA in 2001 as an Assistant Professor, and was promoted to Associate Professor in 2007, and to full Professor in 2011. Dr. Lee graduated from Yale University School of Medicine in 1995 with an M.D. and induction into the National Medical Honor Society (Alpha Omega Alpha), and did his clinical and post-doctoral training at the University of Pennsylvania Medical Center (1995-2001) where he also served as Chief Resident (1997). He worked on HIV fusion and entry during his post-doctoral years under Dr. Robert Doms (1997-2001).

    Dr. Lee is board-certified in Clinical Pathology and was an attending physician on the Transfusion Medicine Service at UCLA.

    Dr. Lee has a special interest in emerging paramyxoviruses such as henipaviruses. He has made substantial contributions to our understanding of henipavirus entry and budding mechanisms. His latest interests include engineering paramyxovirus-based vectors for gene therapy applications. Dr. Lee has published over 140 peer-reviewed publications (h index=47), and sits on multiple editorial boards. He is a member of the NIH recombinant DNA Advisory Committee (RAC), and the ICTV Paramyxovirus study group. He has trained more than a dozen post-doctoral fellows, 16 graduate students, and has served on more than 60 PhD dissertation committees between UCLA and Mount Sinai.

Education & Training

  • University of Pennsylvania Health System
    University of Pennsylvania Health SystemResidency, Pathology-Anatomic and Clinical, 1995 - 2000
  • University of Pennsylvania Health System
    University of Pennsylvania Health SystemChief Residency, Pathology-Anatomic and Clinical, 1996 - 1997
  • Yale School of Medicine
    Yale School of MedicineClass of 1995
  • Santa Clara University
    Santa Clara UniversityBS, Magna cum laude, 1984 - 1988

Certifications & Licensure

  • CA State Medical License
    CA State Medical License 2002 - 2023
  • American Board of Pathology Clinical Pathology

Awards, Honors, & Recognition

  • Recombinant DNA Advisory Committee (RAC) National Institutes of Health (NIH), 2016-2020
  • Paramyxoviridae Study Group International Committee on Taxonomy of Viruses, 2017
  • Scientific Advisor, Standards Working Group California Institute of Regenerative Medicine (SWG, CIRM), 2015-2017
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Publications & Presentations

PubMed

Journal Articles

  • Association of RNase MRP with RNase P in higher ordered structures in the nucleolus: a possible coordinate role in ribosome biogenesis.  
    Lee, B., Matera, G., Ward, D., and Craft, J, Proc Natl Acad Sci USA 93:11471-11476
  • Utilization of chemokine receptors, orphan receptors, and herpesvirus encoded receptors by diverse human and simian immunodeficiency viruses.  
    Rucker, J., Edinger, A.L., Sharron, M., Samson, M., Lee, B., Berson, J., Yi, Y., Collman, R., Doranz, B., Parmentier, M., Doms, R, J Virol 71: 8999-9007
  • CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by neurovirulent SIV.  
    Edinger, A.L., Mankowski, J.L.*, Doranz, B.J.*, Margulies, B.J.*, Lee, B.*, Rucker, J., Sharron, M., Hoffman, T.L., Berson, J.F., Zink, M.C., Hirsch, V.M., Clements, J..., CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by neurovirulent SIV.
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Books/Book Chapters

  • Human Immunodeficiency Virus: Biology, Immunology and Molecular Biology. 
    Chapter: Immune Modulators in HIV-1 Disease 
    Lee, B., Montaner, L.JEditors: N. Saksena.Medical Systems S.P.A, Genova, Italy
  • Cellular Aspects of HIV Infection. 
    Chapter: Quantification of HIV/SIV coreceptor expression 
    Lee, B. and Doms, R.WEditors: Andrea Cossarizza & David R. Kaplan, John Wiley and Sons.New York
  • Microbiology and Immunology. 
    Chapter: Henipavirus: Ecology, Molecular Virology, and Pathogenesis 
    Lee, BEditors: Benhur Lee and Paul Rota.

Lectures

  • Emerging paramyxoviruses: diversity and danger? 
    Yale University Microbiology Seminar Series - 2/16/2017
  • CRISPR-Cas9 Mediated Efficient and Complete Knock-In of Destabilization Domain-Tags Allows for Reversible and Regulated Knock-Out of Protein Function 
    Protein Expression System Engineering, PEGS, Boston, MA - 4/28/2016
  • Out of Africa: Emerging Paramyxovurses 
    Princeton University, Infectious Disease Dynamics Group Research Seminar, Princeton, NJ - 4/13/2016
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Other

Press Mentions

  • Trivalent NDV-HXP-S Vaccine Protects Against Phylogenetically Distant SARS-CoV-2 Variants of Concern in Mice
    Trivalent NDV-HXP-S Vaccine Protects Against Phylogenetically Distant SARS-CoV-2 Variants of Concern in MiceJune 6th, 2022
  • What Is It About the Delta Variant That Makes It Spread so Easily?
    What Is It About the Delta Variant That Makes It Spread so Easily?July 30th, 2021
  • No, There Is No Evidence the COVID-19 Vaccine Spike Protein Is ‘Cytotoxic’
    No, There Is No Evidence the COVID-19 Vaccine Spike Protein Is ‘Cytotoxic’June 24th, 2021
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Dr. Benhur Lee, Dr. Benhur Lee, MD, Dr. B Lee