BenjaminMizukawaMD

PubMed

• 2 citations
  Use of gemcitabine, oxaliplatin, and anti-CD20 therapy in children and adolescents with non-Hodgkin lymphoma unfit for intensive therapy.
  Jonathan D Bender, Jeremy D Rubinstein, Benjamin Mizukawa, John P Perentesis, Lauren Pommert> ;Pediatric Blood & Cancer. 2023 Apr 1
• 3 citations
  IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia.
  Xiaoxiao Liu, Naru Sato, Tomohiro Yabushita, Jingmei Li, Yuhan Jia, Moe Tamura, Shuhei Asada, Takeshi Fujino, Tsuyoshi Fukushima, Taishi Yonezawa, Yosuke Tanaka, Tomof...> ;EMBO Molecular Medicine. 2023 Jan 11
• 2 citations
  Nuclear Vav3 is required for polycomb repression complex-1 activity in B-cell lymphoblastic leukemogenesis.
  R C Nayak, K H Chang, A K Singh, M Kotliar, M Desai, A M Wellendorf, M Wunderlich, J Bartram, B Mizukawa, M Cuadrado, P Dexheimer, A Barski, X R Bustelo, N N Nassar, J...> ;Nature Communications. 2022 Jun 1
• 5 citations
  Inhibition of the RacGEF VAV3 by the small molecule IODVA1 impedes RAC signaling and overcomes resistance to tyrosine kinase inhibition in acute lymphoblastic leukemia.
  Shailaja Hegde, Anjelika Gasilina, Mark Wunderlich, Yuan Lin, Marcel Buchholzer, Oliver H.F. Krumbach, Mohammad Akbarzadeh, Mohammad Reza Ahmadian, William L. Seibel, ...> ;Leukemia. 2021 Oct 28
• 4 citations
  Multicenter Analysis of Genomically Targeted Single Patient Use Requests for Pediatric Neoplasms
  Himalee S. Sabnis, David S. Shulman, Benjamin Mizukawa, Nancy Bouvier, Ahmet Zehir, Jason Fangusaro, Vanessa A Fabrizio, Chanta Whitlow, Marilyn Winchester, Laura Agre...> ;Journal of Clinical Oncology. 2021 Sep 30
• 3 citations
  Treatment of posttransplant lymphoproliferative disorder with poor prognostic features in children and young adults: Short-course EPOCH regimens are safe and effective
  Jeremy D. Rubinstein, Rachana Shah, Erin H. Breese, Karen Burns, Jennifer Mangino, Robin E. Norris, Lynn Lee, Benjamin Mizukawa, Maureen M. O'Brien, Christine L Philli...> ;Pediatric Blood & Cancer. 2021 May 21
• 12 citations
  PD-1 Inhibition Enhances Blinatumomab Response in a UCB/PDX Model of Relapsed Pediatric B-Cell Acute Lymphoblastic Leukemia.
  Mark Wunderlich, Nicole Manning, Christina Sexton, Eric O'Brien, Luke Byerly, Cody Stillwell, John P. Perentesis, James C. Mulloy, Benjamin Mizukawa> ;Frontiers in Oncology. 2021 Apr 13
• 9 citations
  Cyclosporine enhances the sensitivity to lenalidomide in MDS/AML in vitro.
  Xiaofei He, Aixia Dou, Saran Feng, Ashley Roman-Rivera, Caleb Hawkins, Lauren Lawley, Jiajia Zhang, Mark Wunderlich, Benjamin Mizukawa, Stephanie Halene, Amisha Patel,...> ;Experimental Hematology. 2020 Jun 1
• Hyperdiploid Precursor B-acute Lymphoblastic Leukemia Presenting as a Cavernous Sinus Mass in a 4-Year-old Male.
  Anthony Sabulski, Allison L. Bartlett, Bernadette L. Koch, Ralph E. Vatner, Benjamin Mizukawa, Christine L Phillips> ;Journal of Pediatric Hematology/oncology. 2021 May 1
• 52 citations
  FOXM1 regulates leukemia stem cell quiescence and survival in MLL-rearranged AML
  Yue Sheng, Chunjie Yu, Yin Liu, Chao Hu, Rui Ma, Xinyan Lu, Peng Ji, Jianjun Chen, Benjamin Mizukawa, Yong Huang, Jonathan D. Licht, Zhijian Qian> ;Nature Communications. 2020 Feb 17
• 16 citations
  Improved chemotherapy modeling with RAG-based immune deficient mice.
  Mark Wunderlich, Nicole Manning, Christina Sexton, Anthony Sabulski, Luke Byerly, Eric O'Brien, John P. Perentesis, Benjamin Mizukawa, James C. Mulloy> ;Plos One. 2019 Nov 20
• 31 citations
  Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia.
  Y Hayashi, Susumu Goyama, Xiaoxiao Liu, Moe Tamura, Shuhei Asada, Yosuke Tanaka, Tomofusa Fukuyama, Mark Wunderlich, Eric O'Brien, Benjamin Mizukawa, Satoshi Yamazaki,...> ;Nature Communications. 2019 Oct 25
• 25 citations
  Limitations of HLH-2004 criteria in distinguishing malignancy-associated hemophagocytic lymphohistiocytosis.
  Arun Gurunathan, Alexander A. Boucher, Melissa Mark, Kristina M. Prus, Maureen M. O'Brien, Erin H. Breese, Benjamin Mizukawa, Michael J. Absalon, Adam S. Nelson, Micha...> ;Pediatric Blood & Cancer. 2018 Dec 1
• 7 citations
  A non-myeloablative conditioning approach for long-term engraftment of human and mouse hematopoietic stem cells
  Wei Du, Wei Liu, Benjamin Mizukawa, Xun Shang, Jared Sipple, Mark Wunderlich, Hartmut Geiger, Stella Davies, James C. Mulloy, Qishen Pang, Yi Zheng> ;Leukemia. 2018 Jun 29
• Cell Polarity and Division Symmetry Analyses in Transformed Blood Cells
  Benjamin Mizukawa, Eric O'Brien, James C. Mulloy, Yi Zheng> ;Methods in Molecular Biology. 2018 Jan 1
• 87 citations
  Outcomes of adults and children with primary mediastinal B-cell lymphoma treated with dose-adjusted EPOCH-R
  Lisa Giulino-Roth, Tara O'Donohue, Zhengming Chen, Nancy L. Bartlett, Ann S. LaCasce, William Martin-Doyle, Matthew J. Barth, Kimberly Davies, Kristie A. Blum, Beth A....> ;British Journal of Haematology. 2017 Dec 1
• 32 citations
  The cell polarity determinant CDC42 controls division symmetry to block leukemia cell differentiation.
  Benjamin Mizukawa, Eric O'Brien, Daniel C. Moreira, Mark Wunderlich, Cindy L. Hochstetler, Xin Duan, Wei Liu, Emily Orr, H. Leighton Grimes, James C. Mulloy, Yi Zheng> ;Blood. 2017 Sep 14
• 16 citations
  Protease-activated receptor-1 inhibits proliferation but enhances leukemia stem cell activity in acute myeloid leukemia
  Susumu Goyama, Mahesh Shrestha, Janet Schibler, Leah Rosenfeldt, Whitney Miller, Eric O'Brien, Benjamin Mizukawa, Tadaichi Kitamura, Joseph S. Palumbo, James C. Mulloy> ;Oncogene. 2017 May 4
• 30 citations
  A xenograft model of macrophage activation syndrome amenable to anti-CD33 and anti–IL-6R treatment
  Mark Wunderlich, Courtney A. Stockman, Mahima Devarajan, Navin Ravishankar, Christina Sexton, Ashish R Kumar, Benjamin Mizukawa, James C. Mulloy> ;JCI Insight. 2016 Sep 23
• 33 citations
  Functional Niche Competition Between Normal Hematopoietic Stem and Progenitor Cells and Myeloid Leukemia Cells.
  Chen Glait-Santar, Ronan Desmond, Xingmin Feng, Taha Bat, Jichun Chen, Elisabeth F. Heuston, Benjamin Mizukawa, James C. Mulloy, David M. Bodine, Andre Larochelle, Cyn...> ;Stem Cells. 2015 Dec 1
• 29 citations
  Gene targeting RhoA reveals its essential role in coordinating mitochondrial function and thymocyte development
  Shuangmin Zhang, Diamantis G. Konstantinidis, Jun-Qi Yang, Benjamin Mizukawa, Khalid W. Kalim, Richard A. Lang, Theodosia A. Kalfa, Yi Zheng, Fukun Guo> ;Journal of Immunology. 2014 Dec 15
• 145 citations
  Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells
  Susumu Goyama, Janet Schibler, Lea Cunningham, Yue Zhang, Yalan Rao, Nahoko Nishimoto, Masahiro Nakagawa, Andre Olsson, Mark Wunderlich, Kevin A. Link, Benjamin Mizuka...> ;The Journal of Clinical Investigation. 2013 Sep 3
• 87 citations
  AML cells are differentially sensitive to chemotherapy treatment in a human xenograft model.
  Mark Wunderlich, Benjamin Mizukawa, Fu-Sheng Chou, Christina Sexton, Mahesh Shrestha, Yogen Saunthararajah, James C. Mulloy> ;Blood. 2013 Mar 21
• 42 citations
  The thrombopoietin/MPL/Bcl-xL pathway is essential for survival and self-renewal in human preleukemia induced by AML1-ETO
  Fu-Sheng Chou, Andrea Griesinger, Mark Wunderlich, Shan Lin, Kevin A. Link, Mahesh Shrestha, Susumu Goyama, Benjamin Mizukawa, Shuhong Shen, Guido Marcucci, James C. M...> ;Blood. 2012 Jul 26
• 54 citations
  Inhibition of Rac GTPase signaling and downstream prosurvival Bcl-2 proteins as combination targeted therapy in MLL-AF9 leukemia.
  Benjamin Mizukawa, Junping Wei, Mahesh Shrestha, Mark Wunderlich, Fu-Sheng Chou, Andrea Griesinger, Chad E. Harris, Ashish R Kumar, Yi Zheng, David A. Williams, James ...> ;Blood. 2011 Nov 10
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Journal Articles

• A Non-Myeloablative Conditioning Approach for Long-Term Engraftment of Human and Mouse Hematopoietic Stem Cells  
  Benjamin Mizukawa, Stella Davies, Nature

Lectures

• In Vitro Approach for the Identification of Exceptional Responders in Acute Myeloid Leukemia 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
• Proton Sensor GPR68 Is Essential to Maintain Myeloid Malignancies 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018