BernadetteChenMD

PubMed

• 1 citations
  Hypoxic pulmonary endothelial cells release epidermal growth factor leading to vascular smooth muscle cell arginase-2 expression and proliferation.
  Bernadette Chen, Yi Jin, Caitlyn M Pool, Yusen Liu, Leif D Nelin> ;Physiological Reports. 2022 Jun 1
• 2 citations
  Mitogen-activated protein kinase phosphatase-1 controls PD-L1 expression by regulating type I interferon during systemic Escherichia coli infection.
  Timothy J Barley, Parker R Murphy, Xiantao Wang, Bridget A Bowman, Justin M Mormol, Carli E Mager, Sean G Kirk, Charles J Cash, Sarah C Linn, Xiaomei Meng, Leif D Neli...> ;The Journal of Biological Chemistry. 2022 May 1
• 7 citations
  Cyclooxygenase-2 deficiency attenuates lipopolysaccharide-induced inflammation, apoptosis, and acute lung injury in adult mice.
  Leif D Nelin, Yi Jin, Bernadette Chen, Yusen Liu, Lynette K Rogers, Jeff Reese> ;American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 2022 Feb 1
• 1 citations
  Evidence-based guidelines for acute stabilization and management of neonates with persistent pulmonary hypertension of the newborn.
  Molly K. Ball, Ruth Seabrook, Elizabeth M. Bonachea, Bernadette Chen, Omid Fathi, Craig A. Nankervis, Ahmed F. Osman, Amy B. Schlegel, Jacqueline Magers, Taylor Kulpa,...> ;American Journal of Perinatology. 2021 Dec 1
• 3 citations
  Worsened short-term clinical outcomes in a cohort of patients with iNO-unresponsive PPHN: a case for improving iNO responsiveness.
  Julie Dillard, Leeann R. Pavlek, Saichidroopi Korada, Bernadette Chen> ;Journal of Perinatology. 2021 Oct 15
• 3 citations
  Primary pulmonary vein stenosis among premature infants with single-vessel disease.
  Eli T. Zettler, Brian K. Rivera, Corey Stiver, Brian A. Boe, Clifford L. Cua, Molly K. Ball, Charles V. Smith, Jonathan L. Slaughter, Bernadette Chen, Ryan Callahan, C...> ;Journal of Perinatology. 2021 Jul 1
• 5 citations
  Nitric oxide activates AMPK by modulating PDE3A in human pulmonary artery smooth muscle cells.
  Julie Dillard, Xiaomei Meng, Leif D. Nelin, Yusen Liu, Bernadette Chen> ;Physiological Reports. 2020 Sep 1
• 7 citations
  Therapies that enhance pulmonary vascular NO-signaling in the neonate.
  Julie Dillard, Marta Perez, Bernadette Chen> ;Nitric Oxide. 2020 Feb 1
• 7 citations
  Hypoxic-induction of arginase II requires EGF-mediated EGFR activation in human pulmonary microvascular endothelial cells.
  Caitlyn M. Pool, Yi Jin, Bernadette Chen, Yusen Liu, Leif D. Nelin> ;Physiological Reports. 2018 May 1
• 9 citations
  Hypoxic proliferation requires EGFR-mediated ERK activation in human pulmonary microvascular endothelial cells
  Hilary A. White, Yi Jin, Louis G. Chicoine, Bernadette Chen, Yusen Liu, Leif D. Nelin> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2017 May 1
• 21 citations
  Hypoxia induces arginase II expression and increases viable human pulmonary artery smooth muscle cell numbers via AMPKα1 signaling
  Jianjing Xue, Leif D. Nelin, Bernadette Chen> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2017 Feb 17
• 16 citations
  COL4A1 Mutation in a Neonate With Intrauterine Stroke and Anterior Segment Dysgenesis
  Shaheen Durrani-Kolarik, Kandamurugu Manickam, Bernadette Chen> ;Pediatric Neurology. 2017 Jan 1
• 11 citations
  An arginase-1 SNP that protects against the development of pulmonary hypertension in bronchopulmonary dysplasia enhances NO-mediated apoptosis in lymphocytes
  Jennifer K. Trittmann, Yi Jin, Louis G. Chicoine, Yusen Liu, Bernadette Chen, Leif D. Nelin> ;Physiological Reports. 2016 Nov 1
• 12 citations
  The Src family tyrosine kinases src and yes have differential effects on inflammation-induced apoptosis in human pulmonary microvascular endothelial cells
  Leif D. Nelin, Hilary A. White, Yi Jin, Jennifer K. Trittmann, Bernadette Chen, Yusen Liu> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2016 May 1
• 13 citations
  Mitogen-activated protein kinase phosphatase-1 prevents lipopolysaccharide-induced apoptosis in immature rat intestinal epithelial cells
  Maria M Talavera, Nathaniel Kralik, Yi Jin, Bernadette Chen, Yusen Liu, Leif D. Nelin> ;Pediatric Research. 2015 May 7
• 32 citations
  Plasma asymmetric dimethylarginine levels are increased in neonates with bronchopulmonary dysplasia-associated pulmonary hypertension
  Jennifer K. Trittmann, Eric M. Peterson, Lynette K. Rogers, Bernadette Chen, Carl H. Backes, Mark A. Klebanoff, Leif D. Nelin> ;The Journal of Pediatrics. 2015 Feb 1
• 50 citations
  Resveratrol prevents hypoxia-induced arginase II expression and proliferation of human pulmonary artery smooth muscle cells via Akt-dependent signaling
  Bernadette Chen, Jianjing Xue, Xiaomei Meng, Jessica Lauren Slutzky, Andrea E. Calvert, Louis G. Chicoine> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2014 Aug 15
• 15 citations
  Arginase II is a target of miR-17-5p and regulates miR-17-5p expression in human pulmonary artery smooth muscle cells
  Youpeng Jin, Yi Jin, Bernadette Chen, Trent E. Tipple, Leif D. Nelin> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2014 Jul 15
• 9 citations
  Asymmetric dimethylarginine does not inhibit arginase activity and is pro-proliferative in pulmonary endothelial cells.
  Bernadette Chen, Krista Strauch, Yi Jin, Hongmei Cui, Leif D. Nelin, Louis G. Chicoine> ;Clinical and Experimental Pharmacology & Physiology. 2014 Jul 1
• 23 citations
  Arginase I gene single-nucleotide polymorphism is associated with decreased risk of pulmonary hypertension in bronchopulmonary dysplasia.
  Jennifer K. Trittmann, Leif D. Nelin, Erik Zmuda, Julie M. Gastier-Foster, Bernadette Chen, Carl H. Backes, Jessica Frick, P Vaynshtok, Veronica J. Vieland, Mark A. Kl...> ;Acta Paediatrica. 2014 Oct 1
• 25 citations
  Thioredoxin-1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation.
  Bernadette Chen, Viktoria Nelin, Morgan L. Locy, Yi Jin, Trent E. Tipple> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2013 Sep 1
• 20 citations
  Pharmacologic Agents Elevating cAMP Prevent Arginase II Expression and Proliferation of Pulmonary Artery Smooth Muscle Cells
  Bernadette Chen, Andrea E. Calvert, Xiaomei Meng, Leif D. Nelin> ;American Journal of Respiratory Cell and Molecular Biology. 2012 Dec 14
• 5 citations
  Chronic hypoxia decreases arterial and venous compliance in isolated perfused rat lungs: an effect that is reversed by exogenous L-arginine
  Yi Jin, Bernadette Chen, Thomas J. Calvert, Louis G. Chicoine, Yusen Liu, Leif D. Nelin> ;American Journal of Physiology. Heart and Circulatory Physiology. 2013 Jan 15
• 51 citations
  Glutathione Reductase Facilitates Host Defense by Sustaining Phagocytic Oxidative Burst and Promoting the Development of Neutrophil Extracellular Traps
  Jing Yan, Xiaomei Meng, Lyn M. Wancket, Katherine E. Lintner, Leif D. Nelin, Bernadette Chen, Kevin P. Francis, Charles V. Smith, Lynette K. Rogers, Yusen Liu> ;Journal of Immunology. 2012 Mar 1
• 19 citations
  Overexpression of cationic amino acid transporter-1 increases nitric oxide production in hypoxic human pulmonary microvascular endothelial cells
  Hongmei Cui, Bernadette Chen, Louis G. Chicoine, Leif D. Nelin> ;Clinical and Experimental Pharmacology & Physiology. 2011 Dec 1
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