BernhardKuhnMD

PubMed

• 7 citations
  Histone deacetylase 1 controls cardiomyocyte proliferation during embryonic heart development and cardiac regeneration in zebrafish.
  Anja Bühler, Bernd M. Gahr, Deung-Dae Park, Alberto Bertozzi, Alena Boos, Mohankrishna Dalvoy, Alexander Pott, Franz Oswald, Rhett A. Kovall, Bernhard Kühn, Gilbert We...> ;Plos Genetics. 2021 Nov 1
• 8 citations
  Design and rationale of a clinical trial to increase cardiomyocyte division in infants with tetralogy of Fallot.
  Samar R. El Khoudary, Anthony Fabio, Jessie W. Yester, Matthew L. Steinhauser, Adam B. Christopher, Frank Gyngard, Phillip S. Adams, Victor O. Morell, Melita Viegas, J...> ;International Journal of Cardiology. 2021 Sep 15
• 18 citations
  Polyploid cardiomyocytes: implications for heart regeneration
  Anna Kirillova, Lu Han, Honghai Liu, Bernhard Kühn> ;Development. 2021 Jul 15
• 6 citations
  Use of stable isotope-tagged thymidine and multi-isotope imaging mass spectrometry (MIMS) for quantification of human cardiomyocyte division.
  Jessie W. Yester, Honghai Liu, Frank Gyngard, Niyatie Ammanamanchi, Kathryn C. Little, Dawn Thomas, Mara Sullivan, Sean Lal, Matthew L. Steinhauser, Bernhard Kühn> ;Nature Protocols. 2021 Feb 24
• 4 citations
  Isolation and Characterization of Intact Cardiomyocytes from Frozen and Fresh Human Myocardium and Mouse Hearts.
  Honghai Liu, Kevin R. Bersell, Bernhard Kühn> ;Methods in Molecular Biology. 2021 Jan 1
• 3 citations
  Generation of Human Induced Pluripotent Stem Cells and Differentiation into Cardiomyocytes.
  Lu Han, Jocelyn D. Mich-Basso, Bernhard Kühn> ;Methods in Molecular Biology. 2021 Jan 1
• 50 citations
  Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei and Myocardial Regeneration.
  Lu Han, Sangita Choudhury, Jocelyn D. Mich-Basso, Niyatie Ammanamanchi, Balakrishnan Ganapathy, Sangita Suresh, Mugdha Khaladkar, Jennifer M. Singh, René Maehr, Daniel...> ;Developmental Cell. 2020 Apr 6
• 55 citations
  Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment
  Honghai Liu, Cheng-Hai Zhang, Niyatie Ammanamanchi, Sangita Suresh, Christopher M. Lewarchik, Krithika Rao, Gerrida M. Uys, Lu Han, Maryline Abrial, Dean Yimlamai, Bal...> ;Science Translational Medicine. 2019 Oct 9
• Regenerating Hearts by Arresting Development With Hypothyroidism
  Sean Lal, Bernhard Kühn> ;Circulation Research. 2019 Jun 7
• 43 citations
  Dusp6 attenuates Ras/MAPK signaling to limit zebrafish heart regeneration
  Maria A. Missinato, Manush Saydmohammed, Daniel A. Zuppo, Krithika Rao, Graham W. Opie, Bernhard Kühn, Michael Tsang> ;Development. 2018 Mar 1
• 63 citations
  Humanin is an endogenous activator of chaperone-mediated autophagy.
  Zhenwei Gong, Inmaculada Tasset, Antonio Diaz, Jaime Anguiano, Emir Tas, Lingguang Cui, Regina Kuliawat, Honghai Liu, Bernhard Kühn, Ana Maria Cuervo, Radhika Muzumdar> ;The Journal of Cell Biology. 2018 Feb 5
• 36 citations
  Mechanisms of Cardiomyocyte Proliferation and Differentiation in Development and Regeneration.
  Jessie W. Yester, Bernhard Kühn> ;Current Cardiology Reports. 2017 Feb 1
• 11 citations
  Neuregulin-1 Administration Protocols Sufficient for Stimulating Cardiac Regeneration in Young Mice Do Not Induce Somatic, Organ, or Neoplastic Growth.
  Balakrishnan Ganapathy, Nikitha Nandhagopal, Brian D. Polizzotti, David A. Bennett, Alparslan Asan, Yijen L. Wu, Bernhard Kühn> ;Plos One. 2016 May 13
• 36 citations
  A cryoinjury model in neonatal mice for cardiac translational and regeneration research
  Brian D. Polizzotti, Balakrishnan Ganapathy, Bernhard J. Haubner, Josef M. Penninger, Bernhard Kühn> ;Nature Protocols. 2016 Mar 1
• 65 citations
  Deep sequencing reveals cell-type-specific patterns of single-cell transcriptome variation
  Hannah Dueck, Mugdha Khaladkar, Tae Kyung Kim, Jennifer M. Spaethling, Chantal Francis, Sangita Suresh, Stephen A. Fisher, Patrick Seale, Sheryl G. Beck, Tamas Bartfai...> ;Genome Biology. 2015 Jun 9
• 157 citations
  Neuregulin stimulation of cardiomyocyte regeneration in mice and human myocardium reveals a therapeutic window.
  Brian D. Polizzotti, Balakrishnan Ganapathy, Stuart Walsh, Sangita Choudhury, Niyatie Ammanamanchi, David G. Bennett, Cristobal G. dos Remedios, Bernhard J. Haubner, J...> ;Science Translational Medicine. 2015 Apr 1
• 90 citations
  Cardiac regeneration based on mechanisms of cardiomyocyte proliferation and differentiation
  Samuel E. Senyo, Richard T. Lee, Bernhard Kühn> ;Stem Cell Research. 2014 Nov 1
• 4 citations
  Muscling Up the Heart A Preadolescent Cardiomyocyte Proliferation Contributes to Heart Growth
  Cheng-Hai Zhang, Bernhard Kühn> ;Circulation Research. 2014 Sep 26
• 36 citations
  New Mechanistic and Therapeutic Targets for Pediatric Heart Failure Report From a National Heart, Lung, and Blood Institute Working Group
  Kristin M. Burns, Barry J. Byrne, Bruce D. Gelb, Bernhard Kühn, Leslie A. Leinwand, Seema Mital, Gail D. Pearson, Mark D. Rodefeld, Joseph W. Rossano, Brian L. Stauffe...> ;Circulation. 2014 Jul 1
• 54 citations
  Signalling between microvascular endothelium and cardiomyocytes through neuregulin
  Emily M. Parodi, Bernhard Kühn> ;Cardiovascular Research. 2014 May 1
• 115 citations
  Moderate and high amounts of tamoxifen in αMHC-MerCreMer mice induce a DNA damage response, leading to heart failure and death.
  Kevin R. Bersell, Sangita Choudhury, Mariya Mollova, Brian D. Polizzotti, Balakrishnan Ganapathy, Stuart Walsh, Brian Wadugu, Shima Arab, Bernhard Kühn> ;Disease Models & Mechanisms. 2013 Nov 1
• 29 citations
  Subcellular RNA sequencing reveals broad presence of cytoplasmic intron-sequence retaining transcripts in mouse and rat neurons
  Mugdha Khaladkar, Peter T. Buckley, Miler T. Lee, Chantal Francis, Mitra M. Eghbal, Tina Chuong, Sangita Suresh, Bernhard Kühn, James Eberwine, Junhyong Kim> ;Plos One. 2013 Oct 3
• 490 citations
  Cardiomyocyte proliferation contributes to heart growth in young humans.
  Mariya Mollova, Kevin R. Bersell, Stuart Walsh, Jainy Savla, Lala Tanmoy Das, Shin-Young Park, Leslie E. Silberstein, Cristobal G. dos Remedios, Dionne A. Graham, Stev...> ;Proceedings of the National Academy of Sciences of the United States of America. 2013 Jan 22
• 90 citations
  The role of neuregulin/ErbB2/ErbB4 signaling in the heart with special focus on effects on cardiomyocyte proliferation
  Brian Wadugu, Bernhard Kühn> ;American Journal of Physiology. Heart and Circulatory Physiology. 2012 Jun 1
• 30 citations
  Intrapericardial Delivery of Gelfoam Enables the Targeted Delivery of Periostin Peptide after Myocardial Infarction by Inducing Fibrin Clot Formation
  Brian D. Polizzotti, Shima Arab, Bernhard Kühn> ;Plos One. 2012 May 10
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