BilalOmerMD

Pediatric Hematology & Oncology • Houston, TX

Clinical Postdoc Fellow, Pediatric Hematology & Oncology, Baylor College of Medicine

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Office
6701 Fannin St
Tch Children's Cancer Center Cc 1510.00
Houston, TX 77030
Phone+1 832-822-4242

Fax+1 832-825-1453
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Education & Training

Baylor College of MedicineFellowship, Pediatric Hematology/Oncology, 2010 - 2013
Yale-New Haven Medical CenterResidency, Internal Medicine/Pediatrics, 2005 - 2009
Chicago Medical School at Rosalind Franklin University of Medicine and ScienceClass of 2005

Certifications & Licensure

TX State Medical License 2013 - 2025
CT State Medical License 2008 - 2010
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Hematology-Oncology

Clinical Trials

Multivirus-specific T Cells for the Treatment of Virus Infections After Stem Cell Transplant Start of enrollment: 2014 Jun 01
Completed
Not Applicable
Most Closely Human Leukocyte Antigen (HLA)-Matched CMV-specific T Lymphocytes (Viralym-C) Start of enrollment: 2015 Sep 01
Completed
Phase 1
Administration of Donor MultiTAA-Specific T Cells for ALL Start of enrollment: 2016 Feb 01
Active, not recruiting
Phase 1
C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N) Start of enrollment: 2019 Apr 23
Active, not recruiting
Phase 1
C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B) Start of enrollment: 2020 Feb 03
Recruiting
Phase 1
EBV Specific T-Lymphocytes for Treatment of EBV-Positive Lymphoma Start of enrollment: 2022 Oct 31
Recruiting
Phase 1
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

Hematopoietic stem cell transplantation for B-thalassemia major with alemtuzumab.
Sánchez, L., George, A., Leung, K., Friend, B., Bhar, S., Sasa, G., Doherty, E., Craddock, J., Steffin, D., Salem, B., Yassine, K., Omer, B., Martinez, C., Krance, R.,...> ;Pediatric Hematology and Oncology. 2023 Dec 22
Constitutive Interleukin-7 Cytokine Signaling Enhances the Persistence of Epstein-Barr Virus-Specific T-Cells.
Sandhya Sharma, Tim Sauer, Bilal A Omer, Thomas Shum, Lisa A Rollins, Cliona M Rooney> ;International Journal of Molecular Sciences. 2023 Oct 31
21 citations
Posoleucel, an Allogeneic, Off-the-Shelf Multivirus-Specific T-Cell Therapy, for the Treatment of Refractory Viral Infections in the Post-HCT Setting.
Thomas Pfeiffer, Ifigeneia Tzannou, Mengfen Wu, Carlos Ramos, Ghadir Sasa, Caridad Martinez, Premal Lulla, Robert A Krance, Lauren Scherer, Daniel Ruderfer, Swati Naik...> ;Clinical Cancer Research. 2023 Jan 17
4 citations
Cord blood transplantation for nonmalignant disorders: early functional immunity and high survival.
Caridad Martinez, Paibel Aguayo-Hiraldo, Natalia Chaimowitz, Lisa Forbes, Nicholas Rider, Sarah Nicholas, Filiz Seeborg, Javier Chinen, Ivan Chinn, Carla Davis, Howard...> ;Blood Advances. 2023 May 9
8 citations
Long-term follow-up for the development of subsequent malignancies in patients treated with genetically modified IECs.
David H M Steffin, Ibrahim N Muhsen, LaQuisa C Hill, Carlos A Ramos, Nabil Ahmed, Meenakshi Hegde, Tao Wang, Mengfen Wu, Stephen Gottschalk, Sarah B Whittle, Premal D ...> ;Blood. 2022 Jul 7
14 citations
Donor-derived multiple leukemia antigen-specific T-cell therapy to prevent relapse after transplant in patients with ALL.
Swati Naik, Spyridoula Vasileiou, Ifigeneia Tzannou, Manik Kuvalekar, Ayumi Watanabe, Catherine Robertson, Natalia Lapteva, Wang Tao, Mengfen Wu, Bambi Grilley, George...> ;Blood. 2022 Apr 28
9 citations
A Costimulatory CAR Improves TCR-based Cancer Immunotherapy.
Bilal Omer, Mara G Cardenas, Thomas Pfeiffer, Rachel Daum, Mai Huynh, Sandhya Sharma, Nazila Nouraee, Cicilyn Xie, Candise Tat, Silvana Perconti, Stacey Van Pelt, Laur...> ;Cancer Immunology Research. 2022 Apr 1
65 citations
CD70-specific CAR T cells have potent activity against acute myeloid leukemia without HSC toxicity.
Tim Sauer, Kathan Parikh, Sandhya Sharma, Bilal Omer, David Sedloev, Qian Chen, Linus Angenendt, Christoph Schliemann, Michael Schmitt, Carsten Müller-Tidow, Stephen G...> ;Blood. 2021 Jul 29
4 citations
Matched related hematopoietic cell transplant for sickle cell disease with alemtuzumab: the Texas Children’s Hospital experience
Tami John, Brian D. Friend, Khaled Yassine, Ghadir Sasa, Saleh Bhar, Baheyeldin Salem, Bilal Omer, John Craddock, Erin E Doherty, Caridad Martinez, Helen E. Heslop, Ro...> ;Bone Marrow Transplantation. 2021 Jul 17
30 citations
T-Cell Receptor Stimulation Enhances the Expansion and Function of CD19 Chimeric Antigen Receptor–Expressing T Cells
Natalia Lapteva, Margaret Gilbert, Iulia Diaconu, Lisa Rollins, Mina Al-Sabbagh, Swati Naik, Robert A. Krance, Tamara Tripic, Manasa Hiregange, Darshana Raghavan, Olga...> ;Clinical Cancer Research. 2019 Dec 15
2 citations
CD70-specific CAR T-cells have potent activity against Acute Myeloid Leukemia (AML) without HSC toxicity.
Tim Sauer, Kathan Parikh, Sandhya Sharma, Bilal Omer, David Nikolov Sedloev, Qian Chen, Linus Angenendt, Christoph Schliemann, Michael Schmitt, Carsten Müller-Tidow, S...> ;Blood. 2019 Nov 13
7 citations
Allogeneic hematopoietic stem cell transplant for relapsed and refractory non-Hodgkin lymphoma in pediatric patients.
Swati Naik, Caridad Martinez, Bilal Omer, Ghadir S. Sasa, Khaled Yassine, Carl E. Allen, Kala Y. Kamdar, Robert C. Orth, Meng-Fen Wu, Kathryn S. Leung, Stephen Gottsch...> ;Blood Advances. 2019 Sep 24
31 citations
"Mini" bank of only 8 donors supplies CMV-directed T cells to diverse recipients.
Ifigeneia Tzannou, Ayumi Watanabe, Swati Naik, Rachel Elizabeth Daum, Manik Kuvalekar, Kathryn Leung, Caridad Martinez, Ghadir Sasa, Meng-Fen Wu, Adrian P. Gee, Robert...> ;Blood Advances. 2019 Sep 10
163 citations
NK Cells Expressing a Chimeric Activating Receptor Eliminate MDSCs and Rescue Impaired CAR-T Cell Activity against Solid Tumors.
Robin Parihar, Charlotte H. Rivas, Mai Huynh, Bilal Omer, Natalia Lapteva, Leonid S. Metelitsa, Stephen Gottschalk, Cliona M. Rooney> ;Cancer Immunology Research. 2019 Jan 16
11 citations
Chimeric Antigen Receptor Signaling Domains Differentially Regulate Proliferation and Native T Cell Receptor Function in Virus-Specific T Cells
Bilal Omer, Paul Castillo, Haruko Tashiro, Thomas Shum, Mai T A Huynh, Mara Cardenas, Miyuki Tanaka, Andrew Lewis, Tim Sauer, Robin Parihar, Natalia Lapteva, Michael S...> ;Frontiers in Medicine. 2018 Dec 11
21 citations
A New Method for Reactivating and Expanding T Cells Specific for Rhizopus oryzae.
Paul Castillo, Kaylor E. Wright, Dimitrios P. Kontoyiannis, Thomas J. Walsh, Shabnum Patel, Elizabeth Chorvinsky, Swaroop Bose, Yasmin Hazrat, Bilal Omer, Nathaniel D....> ;Molecular Therapy. Methods & Clinical Development. 2018 Jun 15
21 citations
High Incidence of Autoimmune Disease after Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease
Asaf D. Yanir, Imelda C. Hanson, William T. Shearer, Lenora M. Noroski, Lisa R. Forbes, Feliz O. Seeborg, Sarah K. Nicholas, Ivan K. Chinn, Jordan S. Orange, Nicholas ...> ;Biology of Blood and Marrow Transplantation. 2018 Aug 1
13 citations
Current Allogeneic Hematopoietic Stem Cell Transplantation for Pediatric Acute Lymphocytic Leukemia: Success, Failure and Future Perspectives-A Single-Center Experienc...
Asaf D. Yanir, Caridad Martinez, Ghadir Sasa, Kathryn Leung, Stephen Gottschalk, Bilal Omer, Nabil Ahmed, Meenakshi Hegde, Jo Eunji, Hao Liu, Helen E. Heslop, Malcolm ...> ;Biology of Blood and Marrow Transplantation. 2018 Jul 1
15 citations
Outcomes after Allogeneic Transplant in Patients with Wiskott-Aldrich Syndrome.
Alexander Ngwube, I. Celine Hanson, Jordan S. Orange, Nicholas L. Rider, Filiz O. Seeborg, William Shearer, Lenora M. Noroski, Sarah K. Nicholas, Lisa R. Forbes, Kathr...> ;Biology of Blood and Marrow Transplantation. 2017 Nov 1
167 citations
Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells
Thomas Shum, Bilal Omer, Robert L. Kruse, Dimitrios L. Wagner, Kathan Parikh, Zhongzhen Yi, Tim Sauer, Daofeng Liu, Robin Parihar, Paul Castillo, Hao Liu, Malcolm K. B...> ;Cancer Discovery. 2017 Aug 22
287 citations
Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoie...
Ifigeneia Tzannou, Anastasia Papadopoulou, Swati Naik, Kathryn Leung, Caridad Martinez, Carlos A. Ramos, George Carrum, Ghadir Sasa, Premal Lulla, Ayumi Watanabe, Mani...> ;Journal of Clinical Oncology. 2017 Aug 7
95 citations
Treatment of Acute Myeloid Leukemia with T Cells Expressing Chimeric Antigen Receptors Directed to C-type Lectin-like Molecule 1
Haruko Tashiro, Tim Sauer, Thomas Shum, Kathan Parikh, Maksim Mamonkin, Bilal Omer, Rayne H. Rouce, Premal Lulla, Cliona M. Rooney, Stephen Gottschalk, Malcolm K. Brenner> ;Molecular Therapy. 2017 Sep 6
37 citations
Comprehensive Approach for Identifying the T Cell Subset Origin of CD3 and CD28 Antibody–Activated Chimeric Antigen Receptor–Modified T Cells
Michael Schmueck-Henneresse, Bilal Omer, Thomas Shum, Haruko Tashiro, Maksim Mamonkin, Natalia Lapteva, Sandhya Sharma, Lisa Rollins, Gianpietro Dotti, Petra Reinke, H...> ;Journal of Immunology. 2017 Jul 1
62 citations
Vaccination Targeting Native Receptors to Enhance the Function and Proliferation of Chimeric Antigen Receptor (CAR)-Modified T Cells
Miyuki Tanaka, Haruko Tashiro, Bilal Omer, Natasha Lapteva, Jun Ando, Minhtran C. Ngo, Birju Mehta, Gianpietro Dotti, Paul R. Kinchington, Ann M. Leen, Claudia Rossig,...> ;Clinical Cancer Research. 2017 Jul 15
22 citations
Early transduction produces highly functional chimeric antigen receptor-modified virus-specific T-cells with central memory markers: a Production Assistant for Cell Th...
Jiali Sun, Leslie E. Huye, Natalia Lapteva, Maksim Mamonkin, Manasa Hiregange, Brandon Ballard, Olga Dakhova, Darshana Raghavan, April G. Durett, Serena K. Perna, Bila...> ;Journal for Immunotherapy of Cancer. 2015 Feb 18
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Abstracts/Posters

CD70-Specific CAR T Cells Have Potent Activity Against Acute Myeloid Leukemia (AML) without HSC Toxicity
Bilal Omer, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019

Lectures

Myeloablative Conditioning with Alemtuzumab in Matched Related Donor Hematopoietic Cell Transplant for Sickle Cell Disease Prevents Graft-Versus-Host Disease without C...
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018

Press Mentions

Off-the-Shelf T-cell Therapy Effective Against Viral Infections After Allo-HCTJanuary 13th, 2023
T-cell Therapy Fights Viral Infections Following Stem Cell TransplantsJanuary 13th, 2023
Investigational T-cell Therapy for Viral Infection After Allogeneic Stem Cell Transplant Shows 95% Patient ResponseJanuary 12th, 2023
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