BingnanZhangMD

PubMed

• Brief Report: Comprehensive Clinicogenomic Profiling of Small Cell Transformation From-Mutant NSCLC Informs Potential Therapeutic Targets.
  Bingnan Zhang, Whitney Lewis, C Allison Stewart, Benjamin B Morris, Luisa M Solis, Alejandra Serrano, Yuanxin Xi, Qi Wang, Elyse R Lopez, Kyle Concannon, Simon Heeke, ...> ;JTO Clinical and Research Reports. 2024 Feb 1
• 2 citations
  Tumor- and circulating-free DNA methylation identifies clinically relevant small cell lung cancer subtypes.
  Simon Heeke, Carl M Gay, Marcos R Estecio, Hai Tran, Benjamin B Morris, Bingnan Zhang, Ximing Tang, Maria Gabriela Raso, Pedro Rocha, Siqi Lai, Edurne Arriola, Paul Ho...> ;Cancer Cell. 2024 Feb 12
• 60 citations
  Sex Differences in Alzheimer's Disease: Insights From the Multiomics Landscape.
  Lei Guo, Margaret B. Zhong, Larry Zhang, Bin Zhang, Dongming Cai> ;Biological Psychiatry. 2022 Jan 1
• 15 citations
  Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue.
  Yiyi Ma, Eric B. Dammer, Daniel Felsky, Duc M. Duong, Hans-Ulrich Klein, Charles C. White, Maotian Zhou, Benjamin A. Logsdon, Cristin McCabe, Jishu Xu, Minghui Wang, T...> ;Nature Communications. 2021 Dec 2
• 44 citations
  AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation.
  Faten A. Sayed, Lay Kodama, Li Fan, Gillian K. Carling, Joe C. Udeochu, David Le, Qingyun Li, Lu Zhou, Man Ying Wong, Rose Horowitz, Pearly Ye, Hansruedi Mathys, Mingh...> ;Science Translational Medicine. 2021 Dec 1
• 13 citations
  SLFN11 biomarker status predicts response to lurbinectedin as a single agent and in combination with ATR inhibition in small cell lung cancer
  Kiran Kundu, Robert J. Cardnell, Bingnan Zhang, Li Shen, C. Allison Stewart, Kavya Ramkumar, Kasey R. Cargill, Jing Wang, Lauren Averett Byers> ;Translational Lung Cancer Research. 2021 Dec 1
• 26 citations
  Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro.
  Nicholas P. Marotta, Jahan Ara, Norihito Uemura, Marshall G. Lougee, Emily S. Meymand, Bin Zhang, E. James Petersson, John Q. Trojanowski, Virginia M.-Y. Lee> ;Acta Neuropathologica Communications. 2021 Nov 24
• 15 citations
  A brain proteomic signature of incipient Alzheimer's disease in young APOE ε4 carriers identifies novel drug targets.
  Jackson A. Roberts, Vijay R. Varma, Yang An, Sudhir Varma, Julián Candia, Giovanna Fantoni, Vinod Tiwari, Carlos Anerillas, Andrew Williamson, Atsushi Saito, Tina Loef...> ;Science Advances. 2021 Nov 10
• 46 citations
  Integrative metabolomics-genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease.
  Emrin Horgusluoglu, Ryan Neff, Won-Min Song, Minghui Wang, Qian Wang, Matthias Arnold, Jan Krumsiek, Beatriz Galindo-Prieto, Chen Ming, Kwangsik Nho, Gabi Kastenmüller...> ;Alzheimer's & Dementia. 2021 Nov 10
• 13 citations
  Tox2 is required for the maintenance of GC TFH cells and the generation of memory TFH cells.
  Shu Horiuchi, Hanchih Wu, Wen-Chun Liu, Nathalie Schmitt, Jonathan Provot, Yang Liu, Salah Eddine Bentebibel, Randy A. Albrecht, Michael Schotsaert, Christian V. Forst...> ;Science Advances. 2021 Oct 8
• 2 citations
  Author Correction: Brain Cell Type Specific Gene Expression and Co-expression Network Architectures.
  Andrew M. McKenzie, Minghui Wang, Mads E. Hauberg, John F. Fullard, Alexey Kozlenkov, Alexandra B Keenan, Yasmin L. Hurd, Stella Dracheva, Patrizia Casaccia, Panos Rou...> ;Scientific Reports. 2021 Sep 24
• 16 citations
  Effects of microglial depletion and TREM2 deficiency on Aβ plaque burden and neuritic plaque tau pathology in 5XFAD mice.
  Argyro Thalia Delizannis, Annelies Nonneman, Wangchen Tsering, An De Bondt, Ilse Van den Wyngaert, Bin Zhang, Emily S. Meymand, Modupe F. Olufemi, Pyry Koivula, Shaniy...> ;Acta Neuropathologica Communications. 2021 Sep 9
• 35 citations
  MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer's disease pathogenesis.
  Jiqing Cao, Min Huang, Lei Guo, Li Zhu, Jianwei Hou, Larry Zhang, Adriana Pero, Sabrina Ng, Farida El Gaamouch, Gregory A. Elder, Mary Sano, Alison Goate, Julia Tcw, V...> ;Molecular Psychiatry. 2021 Sep 1
• 76 citations
  Microbial signatures in the lower airways of mechanically ventilated COVID-19 patients associated with poor clinical outcome.
  Imran Sulaiman, Matthew Chung, Luis Angel, Jun-Chieh J. Tsay, Benjamin G. Wu, Stephen T. Yeung, Kelsey Krolikowski, Yonghua Li, Ralf Duerr, R. Schluger, Sara A Thannic...> ;Nature Microbiology. 2021 Aug 31
• 20 citations
  A wake-up call for cancer DNA damage: the role of Schlafen 11 (SLFN11) across multiple cancers
  Bingnan Zhang, Kavya Ramkumar, R. Cardnell, C. Allison Stewart, Wei Lien Wang, Junya Fujimoto, Ignacio I. Wistuba, Lauren Averett Byers> ;British Journal of Cancer. 2021 Jul 22
• 27 citations
  Lung Cancer Models Reveal Severe Acute Respiratory Syndrome Coronavirus 2-Induced Epithelial-to-Mesenchymal Transition Contributes to Coronavirus Disease 2019 Pathophy...
  C. Allison Stewart, Kavya Ramkumar, Kasey R. Cargill, Robert J. Cardnell, Monique B. Nilsson, Simon Heeke, Elizabeth M. Park, Samrat T. Kundu, Lixia Diao, Qi Wang, Li ...> ;Journal of Thoracic Oncology. 2021 Jul 16
• 2 citations
  Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons
  Aiqun Li, Samuel Cartwright, Alex J. Yu, Seok-Man Ho, Nadine Schrode, P J Michael Deans, Marliette R. Matos, Meilin Fernandez Garcia, Kayla Townsley, Bin Zhang, Kriste...> ;STAR Protocols. 2021 Jun 3
• 26 citations
  Computational modeling of tau pathology spread reveals patterns of regional vulnerability and the impact of a genetic risk factor.
  Eli J. Cornblath, Howard L. Li, Lakshmi Changolkar, Bin Zhang, Hannah J. Brown, Ronald J. Gathagan, Modupe F. Olufemi, John Q. Trojanowski, Danielle S. Bassett, Virgin...> ;Science Advances. 2021 Jun 1
• 20 citations
  Distinct brain-derived TDP-43 strains from FTLD-TDP subtypes induce diverse morphological TDP-43 aggregates and spreading patterns in vitro and in vivo.
  Sílvia Porta, Yan Xu, Tagan Lehr, Bin Zhang, Emily S. Meymand, Modupe F. Olufemi, Anna Stieber, Edward B. Lee, John Q. Trojanowski, Virginia M.-Y. Lee> ;Neuropathology and Applied Neurobiology. 2021 May 21
• 8 citations
  New Therapies and Biomarkers: Are We Ready for Personalized Treatment in Small Cell Lung Cancer?
  Bingnan Zhang, S. Birer, Mikhail Dvorkin, Jolly Shruti, Lauren Averett Byers> ;American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting. 2021 May 13
• 75 citations
  Artificial intelligence and machine learning-aided drug discovery in central nervous system diseases: State-of-the-arts and future directions
  Sezen Vatansever, Avner Schlessinger, Daniel Wacker, H. Ümit Kaniskan, Jian Jin, Ming-Ming Zhou, Bin Zhang> ;Medicinal Research Reviews. 2021 May 1
• 2 citations
  Microbial signatures in the lower airways of mechanically ventilated COVID19 patients associated with poor clinical outcome.
  Imran Sulaiman, Matthew Chung, Luis F. Angel, Sergei B. Koralov, Benjamin G. Wu, Stephen T. Yeung, Kelsey Krolikowski, Yonghua Li, Ralf Duerr, R. Schluger, Sara A Than...> ;Research Square. 2021 Mar 29
• 24 citations
  Chronic Intermittent Hypoxia Enhances Pathological Tau Seeding, Propagation, and Accumulation and Exacerbates Alzheimer-like Memory and Synaptic Plasticity Deficits an...
  Syed Faraz Kazim, Abhijeet Sharma, Sivaprakasam R. Saroja, Joon Ho Seo, Chloe S. Larson, Aarthi Ramakrishnan, Minghui Wang, Robert D. Blitzer, Li Shen, Catherine Jense...> ;Biological Psychiatry. 2021 Mar 24
• 32 citations
  Prosaposin mediates inflammation in atherosclerosis.
  Mandy M. T. van Leent, Thijs J. Beldman, Yohana C. Toner, Marnix Lameijer, Nils Rother, Siroon Bekkering, Abraham J. P. Teunissen, Xianxiao Zhou, Roy van der Meel, Joo...> ;Science Translational Medicine. 2021 Mar 10
• 8 citations
  Global Profiling of Lysine Accessibility to Evaluate Protein Structure Changes in Alzheimer's Disease.
  Kaiwen Yu, Mingming Niu, Hong Wang, Yuxin Li, Zhiping Wu, Bin Zhang, Vahram Haroutunian, Junmin Peng> ;Journal of the American Society for Mass Spectrometry. 2021 Mar 8
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