BonnieS.GlissonMD

Oncology • Houston, TX

Professor of Medicine, University Tex Houston

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Office
1515 Holcombe Blvd
Houston, TX 77030
Phone+1 713-792-6363

Fax+1 713-792-1220
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Education & Training

University of FloridaFellowship, Hematology and Medical Oncology, 1982 - 1985
University of Virginia Medical CenterResidency, Internal Medicine, 1979 - 1982
Ohio State University College of MedicineClass of 1979

Certifications & Licensure

TX State Medical License 1986 - 2025
OK State Medical License 2020 - 2021
FL State Medical License 1983 - 1987
OH State Medical License 1985 - 1986
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2002-2014
Top Doctors:SE Texas Castle Connolly, 2013
America's Top Doctors for Cancer Castle Connolly, 2005-2013
Super Doctor SuperDoctors.com
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Clinical Trials

Fenretinide in Treating Patients With Recurrent or Metastatic Head and Neck Cancer Start of enrollment: 2000 Sep 01
Completed
Phase 2
ZD1839 (Iressa) for Recurrent or Metastatic Squamous Cell Carcinoma of the Skin Start of enrollment: 2004 May 01
Completed
Phase 2
Erlotinib and Docetaxel With Concomitant Boost Radiation Therapy (XRT) for Head and Neck Squamous Cell Carcinoma (HNSCC) Start of enrollment: 2005 Apr 01
Completed
Phase 1
Gefitinib in Treating Patients Who Are Undergoing Surgery and/or Radiation Therapy for Locally Advanced or Recurrent Squamous Cell Skin Cancer Start of enrollment: 2005 Mar 01
Completed
Phase 2
Sorafenib in Treating Patients With Extensive Stage Small Cell Lung Cancer Start of enrollment: 2005 Jul 01
Completed
Phase 2
Phase I-II for Patients With Recurrent or Refractory Non-small Cell Lung Cancer (NSCLC) Start of enrollment: 2006 Nov 01
Withdrawn
Phase 1, Phase 2
Carboplatin and Docetaxel Followed by Epstein-Barr Virus Cytotoxic T Lymphocytes Start of enrollment: 2009 Nov 01
Completed
Phase 2
Phase II Trial of Erlotinib, Prior to Surgery or Radiation in Patients With Squamous Cell Cancers (SCC) of the Skin Start of enrollment: 2011 Feb 01
Terminated
Phase 2
Erlotinib in Treating Patients With Recurrent or Metastatic Skin Squamous Cell Carcinoma Start of enrollment: 2011 Mar 10
Completed
Phase 2
Rovalpituzumab Tesirine (SC16LD6.5) in Recurrent Small Cell Lung Cancer Start of enrollment: 2013 Jul 01
Completed
Phase 1, Phase 2
A Prospective Observational Study to Evaluate Acute Kidney Injury Biomarkers In Patients Receiving First Cycle of Cisplatin Chemotherapy for Head and Neck Cancers Start of enrollment: 2012 Sep 01
Unknown status
Study of Rovalpituzumab Tesirine (SC16LD6.5) for Third-Line and Later Treatment of Subjects With Relapsed or Refractory Delta-Like Protein 3-Expressing Small Cell Lung Cancer Start of enrollment: 2016 Jan 25
Completed
Phase 2
Utomilumab and ISA101b Vaccination in Patients With HPV-16-Positive Incurable Oropharyngeal Cancer Start of enrollment: 2018 Apr 04
Terminated
Phase 2
A Randomized Phase 2 Study of Cemiplimab ± ISA101b in HPV16-Positive OPC Start of enrollment: 2018 Nov 30
Active, not recruiting
Phase 2
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Publications & Presentations

PubMed

39 citations
Neoadjuvant chemotherapy plus nivolumab with or without ipilimumab in operable non-small cell lung cancer: the phase 2 platform NEOSTAR trial.
Tina Cascone, Cheuk H Leung, Annikka Weissferdt, Apar Pataer, Brett W Carter, Myrna C B Godoy, Hope Feldman, William N William Jr, Yuanxin Xi, Sreyashi Basu, Jing Jing...> ;Nature Medicine. 2023 Mar 1
8 citations
Phase II Clinical Trial of Axitinib and Avelumab in Patients With Recurrent/Metastatic Adenoid Cystic Carcinoma.
Renata Ferrarotto, Luana G Sousa, Lei Feng, Frank Mott, George Blumenschein, Mehmet Altan, Diana Bell, Flavia Bonini, Kaiyi Li, Mario L Marques-Piubelli, Eduardo A Dal...> ;Journal of Clinical Oncology. 2023 May 20
1 citations
Human papillomavirus status and prognosis of oropharyngeal high-grade neuroendocrine carcinoma.
Luana G de Sousa, Felippe Lazar Neto, Eduardo A Dal Lago, Andrew Sikora, Ehab Hanna, Amy Moreno, Jack Phan, Bonnie S Glisson, Diana Bell, Renata Ferrarotto> ;Oral Oncology. 2023 Mar 1
1 citations
Optimal Combination of Neuroendocrine Markers for the Detection of High-Grade Neuroendocrine Tumors of the Sinonasal Tract and Lung.
Annikka Weissferdt, Boris Sepesi, Jing Ning, Mario Hermsen, Renata Ferrarotto, Bonnie Glisson, Ehab Hanna, Diana Bell> ;Current Oncology Reports. 2023 Jan 1
38 citations
ISA101 and nivolumab for HPV-16cancer: updated clinical efficacy and immune correlates of response.
Sousa, L., Rajapakshe, K., Rodriguez Canales, J., Chin, R., Feng, L., Wang, Q., Barrese, T., Massarelli, E., William, W., Johnson, F., Ferrarotto, R., Wistuba, I., Coa...> ;Journal for Immunotherapy of Cancer. 2022 Feb 1
Outcomes of Critically Ill Lung Cancer Patients Initiating Targeted Therapy or Immunotherapy in the Intensive Care Unit: A Single-Center Report.
Felippe Lazar Neto, Luana Guimarães Sousa, Whitney E. Lewis, Bonnie S. Glisson, John V. Heymach, Anne S. Tsao, Renata Ferrarotto> ;Journal of Intensive Care Medicine. 2021 Nov 17
20 citations
Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer
Ming Chen, Runzhe Chen, Ying Jin, Jun Li, Xin Hu, Jiexin Zhang, Junya Fujimoto, Shawna M Hubert, Bo Zhu, Yanhua Tian, Nicholas McGranahan, Won-Chul Lee, Julie George, ...> ;Nature Communications. 2021 Nov 17
8 citations
Treatment patterns and outcomes of palliative systemic therapy in patients with salivary duct carcinoma and adenocarcinoma, not otherwise specified.
Luana Guimarães Sousa, Kaiwen Wang, Danice Torman, Bailee J. Binks, Maria Laura Rubin, Clark R. Andersen, Whitney E. Lewis, Melvin J. Rivera, Diana Kaya, Adel K. El-Na...> ;Cancer. 2021 Oct 18
1 citations
Therapeutic approaches and outcomes in patients with larynx or hypopharynx high-grade neuroendocrine carcinoma: A single-center retrospective analysis
Luana Guimarães Sousa, Felippe Lazar Neto, Danice Torman, Eduardo M. Diaz, David I. Rosenthal, Bonnie S. Glisson, Diana Bell, Renata Ferrarotto> ;Head & Neck. 2021 Sep 15
12 citations
Evaluation of programmed death ligand 1 expression in cytology to determine eligibility for immune checkpoint inhibitor therapy in patients with head and neck squamous...
Michelle A. Williams, John Stewart, Bonnie S. Glisson, Clifton D. Fuller, Sinchita Roy-Chowdhuri> ;Cancer Cytopathology. 2021 Aug 10
7 citations
Elective neck dissection versus observation in patients with head and neck cutaneous squamous cell carcinoma
Moran Amit, Chuan Liu, Jobran Mansour, Frederico O. Gleber-Netto, Samantha Tam, Erez N. Baruch, Mohamed Aashiq, Adel K. El-Naggar, Amy C. Moreno, David I. Rosenthal, B...> ;Cancer. 2021 Aug 6
10 citations
Clinical Outcomes in Non-Small-Cell Lung Cancer Patients Treated With EGFR-Tyrosine Kinase Inhibitors and Other Targeted Therapies Based on Tumor Versus Plasma Genomic...
Hai T. Tran, Vincent K. Lam, Yasir Elamin, Lingzhi Hong, Rivkah Colen, Nabil Elshafeey, Islam Hassan, Mehmet Altan, George R. Blumenschein, Waree Rinsurongkawong, Melv...> ;JCO Precision Oncology. 2021 Aug 5
101 citations
Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancer.
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;Journal for Immunotherapy of Cancer. 2021 Aug 1
6 citations
Pembrolizumab in Patients with Refractory Cutaneous Squamous Cell Carcinoma: A Phase II Trial
Renata Ferrarotto, Luana Guimarães Sousa, Yun Qing, Diana Kaya, Bettzy Stephen, Dipti Jain, Diana Bell, Shubham Pant, Apostolia Maria Tsimberidou, Filip Janku, George ...> ;Advances in Therapy. 2021 Jul 9
51 citations
Pilot Phase II Trial of Neoadjuvant Immunotherapy in Locoregionally Advanced, Resectable Cutaneous Squamous Cell Carcinoma of the Head and Neck.
Renata Ferrarotto, Moran Amit, Priyadharsini Nagarajan, M. Laura Rubin, Ying Yuan, Diana Bell, Adel K. El-Naggar, Jason M. Johnson, William H. Morrison, David I. Rosen...> ;Clinical Cancer Research. 2021 Jun 29
8 citations
Role of induction chemotherapy for oral cavity squamous cell carcinoma.
Ahmed S. Abdelmeguid, Natalie L. Silver, Mongkol Boonsripitayanon, Bonnie S. Glisson, Renata Ferrarotto, G. Brandon Gunn, Jack Phan, Ann M. Gillenwater, Ehab Y. Hanna> ;Cancer. 2021 Sep 1
2 citations
Outcomes of patients with oropharyngeal squamous cell carcinoma treated with induction chemotherapy followed by concurrent chemoradiation compared with those treated w...
Theresa Guo, Faiez K. Saiyed, Christopher M. K. L. Yao, Kimberley L. Kiong, Julian Martinez, Ruth Sacks, J. Jack Lee, Amy C. Moreno, Steven J. Frank, David I. Rosentha...> ;Cancer. 2021 Aug 15
308 citations
Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial.
Tina Cascone, William N. William, Annikka Weissferdt, Cheuk Hong Leung, Heather Lin, Apar Pataer, Myrna C.B. Godoy, Brett W. Carter, Lorenzo Federico, Alexandre Reuben...> ;Nature Medicine. 2021 Feb 18
10 citations
The tumor immune contexture of salivary duct carcinoma.
Gustavo Schvartsman, Diana Bell, Maria Laura Rubin, Michael T. Tetzlaff, Ehab Y. Hanna, J. Jack Lee, Randal S. Weber, Jack Phan, Bonnie S. Glisson, Renata Ferrarotto> ;Head & Neck. 2021 Feb 11
36 citations
Neoadjuvant chemotherapy for locoregionally advanced squamous cell carcinoma of the paranasal sinuses
Ahmed S. Abdelmeguid, Watchareporn Teeramatwanich, Dianna B. Roberts, Moran Amit, Renata Ferraroto, Bonnie S. Glisson, Michael E. Kupferman, Shirley Y. Su, Jack Phan, ...> ;Cancer. 2021 Jun 1
3 citations
Integrating depth of invasion in T classification improves the prognostic performance of the American Joint Committee on Cancer primary tumor staging system for cutane...
Moran Amit, Chuan Liu, Frederico Omar Netto Gleber, Sameer Kini, Samantha Tam, Avi Benov, Mohamed Aashiq, Adel K. El-Naggar, Amy C. Moreno, David I. Rosenthal, Bonnie ...> ;European Journal of Cancer. 2021 Feb 1
1 citations
Cytotoxic and targeted systemic therapy in patients with advanced cutaneous squamous cell carcinoma in the head and neck
Samantha Tam, Mona Gajera, Xiaoning Luo, Bonnie S. Glisson, Renata Ferrarotto, Faye M. Johnson, Frank E. Mott, Maura L. Gillison, Charles Lu, Xiuning Le, George R. Blu...> ;Head & Neck. 2021 Feb 1
354 citations
Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities
C. Allison Stewart, Elizabeth M. Park, Lixia Diao, Sarah M. Groves, Simon Heeke, Barzin Y. Nabet, Junya Fujimoto, Luisa M. Solis, Wei Lu, Yuanxin Xi, Robert J. Cardnel...> ;Cancer Cell. 2021 Mar 8
6 citations
Inclusion of extranodal extension in the lymph node classification of cutaneous squamous cell carcinoma of the head and neck
Moran Amit, Chuan Liu, Frederico O. Gleber-Netto, Sameer Kini, Samantha Tam, Avi Benov, Mohamed Aashiq, Adel K. El-Naggar, Amy C. Moreno, David I. Rosenthal, Bonnie S....> ;Cancer. 2021 Apr 15
40 citations
Phase 1/2 Trial of Pembrolizumab and Concurrent Chemoradiation Therapy for Limited-Stage SCLC.
James W. Welsh, John V. Heymach, Chunxiao Guo, Hari Menon, Katherine Klein, Taylor R. Cushman, Vivek Verma, Kenneth R. Hess, Girish S. Shroff, Chad Tang, Ferdinandos S...> ;Journal of Thoracic Oncology. 2020 Dec 1
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Journal Articles

PI3‐Kinase Pathway Biomarkers in Oral Cancer and Tumor Immune Cells
Bonnie S Glisson, Jeffrey Myers, N Jr William, Renata Ferrarotto, Head & Neck
Combining Immune Checkpoint Blockade and Tumor-Specific Vaccine for Patients with Incurable Human Papillomavirus 16–Related Cancer
Erminia Massarelli, William William, Ming Guo, Merrill Kies, Bonnie Glisson, Hai Tran, Faye Johnson, Renata Ferrarotto, Lei Feng, JAMA
Landscape of EGFR -Dependent and -Independent Resistance Mechanisms to Osimertinib and Continuation Therapy Post-Progression in EGFR-Mutant NSCLC
Stephen G Swisher, Vassiliki A Papadimitrakopoulou, John V Heymach, Jack A Roth, Jianjun Zhang, William N William, Bonnie S Glisson, Clinical Cancer Research

Press Mentions

MD Anderson Research Highlights for March 9, 2022March 9th, 2022
How I Dealt with My Worst Lung Cancer Symptom and Side EffectDecember 13th, 2018
An Immunotherapy Clinical Trial Stabilized My DiseaseNovember 29th, 2018
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Grant Support

Career Development ProgramNational Cancer Institute2008–2011
In Vitro Correlates Of Drug Sensitivity In Lung CancerNational Cancer Institute1992–1993
NCI Clinical Investigator Award ProgramNational Cancer Institute1987–1989