BradleyWBlaserMD

PubMed

• CD200 is overexpressed in the pancreatic tumor microenvironment and predictive of overall survival.
  Jessica Wedig, Shrina Jasani, Debasmita Mukherjee, Hannah Lathrop, Priya Matreja, Timothy Pfau, Liliana D'Alesio, Abigail Guenther, Lexie Fenn, Morgan Kaiser, Molly A ...> ;Cancer Immunology, Immunotherapy. 2024 Apr 15
• Single-Cell RNA-Seq Analysis of Patient Myeloid-Derived Suppressor Cells and the Response to Inhibition of Bruton's Tyrosine Kinase.
  Savardekar, H., Allen, C., Jeon, H., Li, J., Quiroga, D., Schwarz, E., Wu, R., Zelinskas, S., Lapurga, G., Abreo, A., Stiff, A., Shaffer, J., Blaser, B., Old, M., Weso...> ;Molecular Cancer Research. 2024 Mar 1
• Resistance to PRMT5-targeted therapy in mantle cell lymphoma.
  Mackenzie Elizabeth Long, Shirsha Koirala, Shelby Sloan, Fiona Brown-Burke, Christoph Weigel, Lynda Villagomez, Kara Corps, Archisha Sharma, Ian Hout, Margaret Harper,...> ;Blood Advances. 2024 Jan 9
• 1 citations
  Microenvironmental control of hematopoietic stem cell fate via CXCL8 and protein kinase C.
  Binder, V., Li, W., Faisal, M., Oyman, K., Calkins, D., Shaffer, J., Teets, E., Sher, S., Magnotte, A., Belardo, A., Deruelle, W., Gregory, T., Orwick, S., Hagedorn, E...> ;Cell Reports. 2023 May 30
• 9 citations
  Dysregulation of PRMT5 in chronic lymphocytic leukemia promotes progression with high risk of Richter's transformation.
  Zachary A Hing, Janek S Walker, Ethan C Whipp, Lindsey Brinton, Matthew Cannon, Pu Zhang, Steven Sher, Casey B Cempre, Fiona Brown, Porsha L Smith, Claudio Agostinelli...> ;Nature Communications. 2023 Jan 6
• 3 citations
  BMX kinase mediates gilteritinib resistance in FLT3-mutated AML through microenvironmental factors.
  Daelynn R Buelow, Bhavana Bhatnagar, Shelley J Orwick, Jae Yoon Jeon, Eric D Eisenmann, Jack C Stromatt, Navjot Singh Pabla, James S Blachly, Sharyn D Baker, Bradley W...> ;Blood Advances. 2022 Sep 13
• 3 citations
  A sumoylation program is essential for maintaining the mitotic fidelity in proliferating mantle cell lymphoma cells.
  Walter Hanel, Pushpa Lata, Youssef Youssef, Ha Tran, Liudmyla Tsyba, Lalit Sehgal, Bradley W Blaser, Dennis Huszar, JoBeth Helmig-Mason, Liwen Zhang, Morgan S Schrock,...> ;Experimental Hematology & Oncology. 2022 Jul 13
• An Optimized Zebrafish Nursery Feeding Regimen Improves Growth Rates and Labor Costs.
  Toi A Collins, Shelby Cabrera, Emily M Teets, Jami Shaffer, Bradley W. Blaser> ;Zebrafish. 2021 Sep 20
• 3 citations
  Inhibition of MET Signaling with Ficlatuzumab in Combination with Chemotherapy in Refractory AML: Clinical Outcomes and High-Dimensional Analysis
  Victoria E. Wang, Bradley W. Blaser, Ravi K. Patel, Gregory K. Behbehani, Arjun A. Rao, Blythe Durbin-Johnson, Tommy Jiang, Aaron C Logan, Matthew L. Settles, Gabriel ...> ;Blood Cancer Discovery. 2021 Jul 16
• 7 citations
  Incidence of venous thrombosis after peg-asparaginase in adolescent and young adults with acute lymphoblastic leukemia.
  Brynne Underwood, Qiuhong Zhao, Alison Walker, Alice S. Mims, Sumithira Vasu, Meixiao Long, Tamanna Haque, Bradley W. Blaser, Nicole Grieselhuber, Sarah A Wall, Gregor...> ;International Journal of Hematologic Oncology. 2020 Sep 4
• 50 citations
  CD200 promotes immunosuppression in the pancreatic tumor microenvironment
  Fouad Choueiry, Molly Torok, Reena Shakya, Kriti Agrawal, Anna Deems, Brooke Benner, Alice Hinton, Jami Shaffer, Bradley W. Blaser, Anne M. Noonan, Terence M. Williams...> ;Journal for Immunotherapy of Cancer. 2020 Jun 1
• 5 citations
  Quantifying Hematopoietic Stem Cell Clonal Diversity by Selecting Informative Amplicon Barcodes.
  Emily M Teets, Charles Thomas Gregory, Jami Shaffer, James S. Blachly, Bradley W. Blaser> ;Scientific Reports. 2020 Feb 7
• 14 citations
  Making HSCs in vitro: don't forget the hemogenic endothelium.
  Bradley W. Blaser, Leonard I. Zon> ;Blood. 2018 Sep 27
• 34 citations
  CXCR1 remodels the vascular niche to promote hematopoietic stem and progenitor cell engraftment.
  Bradley W. Blaser, Jessica Moore, Elliott J. Hagedorn, Brian Li, Raquel Riquelme, Song Yang, Yi Zhou, Owen J. Tamplin, Vera Binder, Leonard I. Zon> ;The Journal of Experimental Medicine. 2017 Mar 28
• 8 citations
  Generation of Parabiotic Zebrafish Embryos by Surgical Fusion of Developing Blastulae
  Elliott J. Hagedorn, Jennifer L. Cillis, Caitlyn R. Curley, Taylor C. Patch, Brian Li, Bradley W. Blaser, Raquel Riquelme, Leonard I. Zon, Dhvanit I. Shah> ;Journal of Visualized Experiments. 2016 Jun 11
• 36 citations
  Hyperlipidemia and statin use after allogeneic hematopoietic stem cell transplantation.
  Bradley W. Blaser, Haesook T. Kim, Edwin P. Alyea, Vincent T. Ho, Corey Cutler, Philippe Armand, John Koreth, Joseph H. Antin, Jorge Plutzky, Robert J. Soiffer> ;Biology of Blood and Marrow Transplantation. 2012 Apr 1
• 49 citations
  In Vivo Role of Flt3 Ligand and Dendritic Cells in NK Cell Homeostasis
  Martin Guimond, Aharon G. Freud, Hsiaoyin C. Mao, Jianhua Yu, Bradley W. Blaser, Jeffrey W. Leong, Jeffrey VanDeusen, Adrienne M. Dorrance, Jianying Zhang, Crystal L. ...> ;Journal of Immunology. 2010 Mar 15
• 14 citations
  A novel mouse model for the aggressive variant of NK cell and T cell large granular lymphocyte leukemia.
  Akihiko Yokohama, Anjali Mishra, Takeki Mitsui, Brian Becknell, Jessica Johns, Douglas P. Curphey, Bradley W. Blaser, Jeffrey VanDeusen, Hsiaoyin Mao, Jianhua Yu, Mich...> ;Leukemia Research. 2010 Feb 1
• 306 citations
  Preclinical characterization of 1-7F9, a novel human anti–KIR receptor therapeutic antibody that augments natural killer–mediated killing of tumor cells
  François Romagné, Pascale Andre, Pieter Spee, Stefan Zahn, Nicolas Anfossi, Laurent Gauthier, Marusca Capanni, Loredana Ruggeri, Don M. Benson, Bradley W. Blaser, Mari...> ;Blood. 2009 Sep 24
• 43 citations
  The PP2A inhibitor SET regulates natural killer cell IFN-γ production
  Rossana Trotta, David Ciarlariello, Jessica Dal Col, Jeffrey Allard, Paolo Neviani, Ramasamy Santhanam, Hsiaoyin Mao, Brian Becknell, Jianhua Yu, Amy K. Ferketich, Bri...> ;The Journal of Experimental Medicine. 2007 Oct 1
• 4 citations
  Induction of folate receptor type beta in a bone marrow engraftment model of acute myelogenous leukemia.
  Bradley W. Blaser, Mesfin Gonit, H Qi, Aymen Shatnawi, Martin Guimond, Robert J. Lee, Manohar Ratnam> ;Leukemia. 2007 Jun 7
• 107 citations
  Pharmacologic inhibition of CDK4/6: mechanistic evidence for selective activity or acquired resistance in acute myeloid leukemia
  Lisheng Wang, Jie Wang, Bradley W. Blaser, Anne Marie Duchemin, Donna Frances Kusewitt, Tom Liu, Michael A. Caligiuri, Roger Briesewitz> ;Blood. 2007 Sep 15
• 272 citations
  FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome–positive acute lymphocytic leukemia
  Paolo Neviani, Ramasamy Santhanam, Joshua J. Oaks, Anna M. Eiring, Mario Notari, Bradley W. Blaser, Shujun Liu, Rossana Trotta, Natarajan Muthusamy, Carlo Gambacorti-P...> ;The Journal of Clinical Investigation. 2007 Sep 4
• 22 citations
  Hlx homeobox transcription factor negatively regulates interferon-γ production in monokine-activated natural killer cells
  Brian Becknell, Tiffany Hughes, Aharon G. Freud, Bradley W. Blaser, Jianhua Yu, Rossana Trotta, Hsiaoyin C. Mao, Marie L. Caligiuri de Jesús, Mohamad Alghothani, Don M...> ;Blood. 2007 Mar 15
• 22 citations
  Trans-presentation of donor-derived interleukin 15 is necessary for the rapid onset of acute graft-versus-host disease but not for graft-versus-tumor activity
  Bradley W. Blaser, Noah R. Schwind, Seth E. Karol, Dennis Chang, Samuel Shin, Sameek Roychowdhury, Brian Becknell, Amy K. Ferketich, Donna Frances Kusewitt, Bruce R. B...> ;Blood. 2006 Oct 1
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Abstracts/Posters

• Cxcl8 Expands Hematopoietic Stem and Progenitor Cells and Alters Their Interaction with the Endothelial Niche
  Bradley W Blaser, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019

Lectures

• Enumerating Functional HSC Clones in the Zebrafish Using Gestalt 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019