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Office
15 Parkman St
Wac 835
Boston, MA 02114Phone+1 617-726-1728Fax+1 617-724-1480- Is this information wrong?
Education & Training
- University of Iowa Hospitals and ClinicsFellowship, Neuropathology, 1988 - 1989
- University of Iowa Hospitals and ClinicsResidency, Neurology, 1985 - 1988
- University of Iowa Hospitals and ClinicsInternship, Internal Medicine, 1984 - 1985
- University of Iowa Roy J. and Lucille A. Carver College of MedicineClass of 1983
Certifications & Licensure
- NH State Medical License 2021 - 2025
- MA State Medical License 1989 - 2025
- ME State Medical License 2021 - 2024
- IA State Medical License 1984 - 1990
- American Board of Psychiatry and Neurology Neurology
Publications & Presentations
PubMed
- SORL1 is a receptor for tau that promotes tau seeding.Joanna M Cooper, Aurelien Lathuiliere, Enming J Su, Yuyu Song, Daniel Torrente, Youhwa Jo, Nicholas Weinrich, Jennifer Diaz Sales, Mary Migliorini, Thomas H Sisson, Da...> ;The Journal of Biological Chemistry. 2024 Apr 22
- Characterization of monoamine oxidase-B (MAO-B) as a biomarker of reactive astrogliosis in Alzheimer's disease and related dementias.Clara Muñoz-Castro, Molly A Healey, Bradley T Hyman, Alberto Serrano-Pozo, Methasit Jaisa-Aad> ;Acta Neuropathologica. 2024 Apr 3
- APOE2 gene therapy reduces amyloid deposition and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease.Rosemary J Jackson, Megan S Keiser, Jonah C Meltzer, Dustin P Fykstra, Steven E Dierksmeier, Soroush Hajizadeh, Johannes Kreuzer, Robert Morris, Alexandra Melloni, Tsu...> ;Molecular Therapy. 2024 May 1
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Journal Articles
- Dissecting the Genetic Relationship Between Cardiovascular Risk Factors and Alzheimer’s DiseaseChristine M Glastonbury, Fanny M Elahi, Reisa A Sperling, William P Dillon, Lindsay A Farrer, Rahul S Desikan, Christopher P Hess, James B Brewer, Bradley T Hyman, Kri..., Acta Neuropathologica
- Absence of Alzheimer Disease Neuropathologic Changes in Eyes of Subjects with Alzheimer DiseaseBradley T. Hyman, Nora Laver, Declan McGuone, Journal of Neuropathology & Experimental Neurology
Press Mentions
- A Novel Age-Informed Approach for Genetic Association Analysis in Alzheimer’s DiseaseApril 1st, 2021
- Does Astrocyte Tau Cause Dementia?November 13th, 2020
- Decline in Cognitively Complex Everyday Activities Accelerates Along the Alzheimer’s Disease ContinuumOctober 29th, 2020
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Grant Support
- Calcineurin-Mediated Neurodegeneration In Alzheimer DiseaseNational Institute On Aging2011–2012
- A Model Of Early Alzheimer DiseaseNational Institute On Aging2011–2012
- Neuropathological Correlates Of Oligomeric Amyloid BetaNational Institute On Aging2009–2012
- AdministrativeNational Institute On Aging2009–2012
- Massachusetts Alzheimer'S Disease Research CenterNational Institute On Aging2006–2012
- Anatomical Changes In TAU Transgenic ModelsNational Institute On Aging2010–2011
- Peripherally Administered Gene Therapy For Alzheimer'SNational Institute On Aging2009–2011
- LRP And Alzheimer'S DiseaseNational Institute On Aging2000–2011
- Faculty Recruitment For Programs In The Biology Of Age-Related Cognitive ChangeNational Institute On Aging2009–2010
- Neurologic Alterations In Alzheimer'S DiseaseNational Institute On Aging2006–2010
- Anatomical Changes In TAU Trangenic ModelsNational Institute On Aging2004–2010
- Core--ScientificNational Institute Of Neurological Disorders And Stroke2008
- TAU Alterations In Alzheimer'S And Related DementiasNational Institute On Aging2004–2008
- Molecular Chaperones In Lewy Body DiseasesNational Institute Of Neurological Disorders And Stroke2004–2008
- Gamma Secretase And Substrate InteractionsNational Institute On Aging2007
- Core--ScientificNational Institute Of Neurological Disorders And Stroke2004–2007
- Neuroanatomical Alterations In Alzheimer'S DiseaseNational Institute On Aging2001–2005
- Core--NeuropathologyNational Institute On Aging2002
- Genetic Modifiers Of Amyloid Beta Deposition--Neuroanatomic CorrelatesNational Institute On Aging1999–2002
- APOE And Transgenic Models Of Alzheimers DiseaseNational Institute On Aging1999–2002
- Transgenics And Presenilin FunctionNational Institute On Aging1998–2002
- Role Of Alpha Synuclein In Lewy Body DiseaseNational Institute Of Neurological Disorders And Stroke1998–2002
- Presenilins And Alzheimers DiseaseNational Institute On Aging1997–1999
- Neuropathological Alterations In Alzheimers DiseaseNational Institute On Aging1995–1999
- Signature Of Regional And Neuronal Vulnerability In ADNational Institute On Aging1996–1998
- Core--Brain Microdissection, RNA And Protein AnalysisNational Institute On Aging1996–1998
- Structural And Molecular Correlates Of Cognitive Function In Alzheimer'S DiseaseNational Institute On Aging1994–1998
- Apolipoprotein E And Alzheimers DiseaseNational Institute On Aging1994–1998
- Pathological Alterations In Alzheimer'S DiseaseNational Institute On Aging1989–1993
Hospital Affiliations
- Massachusetts General HospitalBoston, Massachusetts
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