Brennan Spiegel MD

PubMed

• The Vibrating Capsule: Safety and Tolerability in Patients With Chronic Idiopathic Constipation.
  Bryan F Curtin, Eamonn M M Quigley, William D Chey, Anthony J Lembo, Darren M Brenner
  Neurogastroenterology and Motility. 2025-05-01
• Virtual reality for menopause symptom management: opportunities, challenges, and next steps.
  Nancy Safwan, Karisma K Suchak, Omer Liran, Sheryl A Kingsberg, Brennan M R Spiegel
  Menopause. 2025-05-01
• Development and Validation of Crohn's Perianal Fistula Educational Videos and Website for Increasing Patient Knowledge and Engagement.
  Carine Khalil, Muskaan Mehra, Yixin Yang, So Yung Choi, Jan Ballesteros
  Journal of Clinical Gastroenterology. 2025-03-25

Journal Articles

• Rome IV Design of Treatment Trials for FGIDs  
  Spiegel B, Irvine JE, Tack J, Crowell MD, Gwee KA, Ke M, Schmulson W MJ, Gastroenterology, 1/18/2016
• Reply  
  Cohen E, Spiegel B, Clin Gastroenterol Hepatol, 1/15/2013
• Adenoma detection rate is necessary but insufficient for distinguishing high versus low endoscopist performance  
  Wang HS, Pisegna J, Modi R, Liang LJ, Atia M, Nguyen M, Cohen H, Ohning G, van Oijen M, Spiegel BM, Gastrointest Endosc, 1/1/2013
• Gastroprotective Strategies in Chronic NSAID Users: A Cost-Effectiveness Analysis Comparing Single-Tablet Formulations with Individual Components  
  de Groot NL, Spiegel BM, van Haalen HG, de Wit NJ, Siersema PD, van Oijen MG, Value Health, 1/1/2013
• Burden of illness in irritable bowel syndrome: looking beyond the patient  
  Spiegel BM, Clin Gastroenterol Hepatol, 1/1/2013
• Assessing Health Status in Inflammatory Bowel Disease Using a Novel Single-Item Numeric Rating Scale  
  Surti B, Spiegel B, Ippoliti A, Vasiliauskas EA, Simpson P, Shih DQ, Targan SR, McGovern DP, Melmed GY, Dig Dis Sci, 1/19/2012
• Setting priorities for comparative effectiveness research in inflammatorybowel disease: Results of an international provider survey, expert RAND panel,and patient focu...  
  Cheifetz AS, Melmed GY, Spiegel B, Talley J, Devlin SM, Raffals L, Irving PM, Jones J, Kaplan GG, Kozuch P, Sparrow M, Velayos F, Baidoo L, Bressler B, Siegel CA, Inflamm Bowel Dis, 1/15/2012
• Intestinal microbiota in functional bowel disorders: a Rome foundation report  
  Simren M, Barbara G, Flint HJ, Spiegel BM, Spiller RC, Vanner S, Verdu EF,Whorwell PJ, Zoetendal EG, Gut, 1/10/2012
• Diverticular Disease as a Chronic Illness: Evolving Epidemiologic and Clinical Insights  
  Strate LL, Modi R, Cohen E, Spiegel BM, Am J Gastroenterol, 1/10/2012
• Conflicts of interest ethics: silencing expertise in the development of international clinical practice guidelines  
  Jones DJ, Barkun AN, Lu Y, Enns R, Sinclair P, Martel M, Gralnek I, Bardou M, Kuipers EJ, Sung J; International Consensus Upper Gastrointestinal Bleeding Conference Group, Ann Intern Med, 1/5/2012
• Feasibility and Construct Validity of PROMIS and "Legacy" Instruments in an Academic Scleroderma Clinic  
  Khanna D, Maranian P, Rothrock N, Cella D, Gershon R, Khanna PP, Spiegel B, Furst DE, Clements PJ, Bechtel A, Hays RD, Value Health, 1/1/2012
• H pylori: should we still be looking for it? What should we be doing about it? A case-based approach  
  Spiegel B, Dig Endosc, 1/1/2012
• Treatment center characteristics associated with better outcomes: a role for the medical director?  
  Spiegel BM, Semin Dial, 1/1/2012
• Direct medical care costs among pegylated infereron plus ribavirin-treated and untreated chronic hepatitis C patients  
  Solomon M, Bonafede M, Pan K, Wilson K, Beam C, Chakravarti P, Spiegel B, Dig Dis Sci, 1/30/2011
• Two weeks of rifaximin relieves global symptoms and bloating in people with IBS without constipation  
  Spiegel B, Evid Based Med, 1/24/2011
• Impact of nasogastric lavage on outcomes in acute GI bleeding  
  Huang ES, Karsan S, Kanwal F, Singh I, Makhani M, Spiegel BM, Gastrointest Endosc, 1/6/2011
• Development and validation of a novel patient educational booklet to enhance colonoscopy preparation  
  Spiegel BMR, Talley J, Shekelle P, Bolus R, Kurzbard N, Chan M, Ho A, Kaneshiro M, Cordasco K, Cohen H, Am J Gastroenterol, 1/1/2011
• Atherosclerosis in systemic sclerosis: a systematic review and meta-analysis  
  Au K, Singh MK, Bodulkam V, Bae S, Maranian P, Ogawa R, Spiegel B, McMahon M, Hahn B, Khanna D, Arthritis Rheum, 1/1/2011
• Screening for high risk individuals for hepatitis B: physician knowledge, attitudes, and beliefs  
  Foster T, Hon H, Kanwal F, Han S, Spiegel B, Dig Dis Sci, 1/1/2011
• The effect of irritable bowel syndrome on health-related quality of life and health care expenditures  
  Agarwal N, Spiegel BM, Gastroenterol Clin North Am, 1/1/2011
• Questioning the bacterial hypothesis of IBS: an epidemiological and evolutionary perspective  
  Spiegel BM, Clinical Gastroenterology and Hepatology, 1/1/2011
• Understanding gastrointestinal distress: a framework for clinical practice  
  Spiegel BM, Khanna D, Bolus R, Agarwal N, Khanna P, Chang L, Am J Gastroenterol, 1/1/2011
• Does time of day affect polyp detection rates from colonoscopy?  
  Spiegel BM, Gastrointest Endosc, 1/1/2011
• Patient-Reported Outcomes Measurement Information System (PROMIS®)-The future of measuring patient reported outcomes in rheumatology  
  Khanna D, Krishnan E, Dewitt EM, Khanna PP, Spiegel B, Hays RD, Arthritis Care Res(Hoboken), 1/1/2011
• The future of measuring patient-reported outcomes in rheumatology: Patient-Reported Outcomes Measurement Information System (PROMIS)  
  Khanna D, Krishnan E, Dewitt EM, Khanna PP, Spiegel B, Hays RD, Arthritis Care Res(Hoboken), 1/1/2011
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Books/Book Chapters

• Acing the Pancreaticobiliary Questions on the GI Board Exam: The Ultimate Crunch-Time Resource 
  Spiegel B and Karsan HSLACK Inc.2017
• Acing the GI Board Exam: The Ultimate Crunch-Time Resource 
  Spiegel BSLACK Inc.Edition 2nd,2015
• Acing the IBD Questions on the GI Board Exam: The Ultimate Crunch-Time Resource 
  Spiegel B and Karsan HSLACK Inc.2013
• Acing the Hepatology Questions on the GI Board Exam: The Ultimate Crunch-Time Resource 
  Spiegel B and Karsan HSLACK Inc.2011
• Acing the GI Board Exam: The Ultimate Crunch-Time Resource 
  Spiegel BSLACK Inc.2009
• Intensive Care Medicine 
  Chapter: Gastrointestinal motility problems in the critical care setting. 
  Spiegel BMR, Singh IEditors: Irwin, Rippe.Lippincott, Williams & Wilkins2006
• Hospital Medicine 
  Chapter: Peptic ulcer disease and stress-related mucosal disease. 
  Spiegel BMR, Dulai GSEditors: Wachter B, Goldman L, Hollander H.Lippincott, Williams & Wilkins2005
• PDxMD Gastroenterology 
  Chapter: "Diverticular disease" 
  Spiegel BEditors: Ferri FF.Elsevier Sciences, Philadelphia2003
• PDxMD Gastroenterology 
  Chapter: "Irritable bowel syndrome" 
  Spiegel BEditors: Ferri FF.Elsevier Sciences, Philadelphia2003
• PDxMD Gastroenterology 
  Chapter: "Pancreatitis" 
  Spiegel BEditors: Ferri FF.Elsevier Sciences, Philadelphia2003
• PDxMD Gastroenterology 
  Chapter: "Peptic ulcer" 
  Spiegel BEditors: Ferri FF.Elsevier Sciences, Philadelphia2003
• PDxMD Gastroenterology 
  Chapter: "Proctitis" 
  Spiegel BEditors: Ferri FF.Elsevier Sciences, Philadelphia2003
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Abstracts/Posters

• Post Diverticulitis (DV) Depression: Longitudinal Analysis Reveals Higher Incidence in Cases vs. Controls.
  Vu M, Fuller G, Bolus R, Snyder B, Cohen E, Shahedi K, Shah R, Modi R, Atia M, Kurzbard N, Sheen V, Agarwal N, Kaneshiro M, Yen L, Hodgkins P, Poysophon P, Spiegel B, Digestive Disease Week, 1/1/2013
• GERD Symptoms in the General Population: Prevalence and Severity vs. Care Seeking Patients.
  Cohen E, Bolus R, Khanna D, Hays RD, Chang L, Melmed G, Khanna P, Spiegel B, Digestive Disease Week, 1/1/2013
• How well do physicians perceive severity of patients' gastrointestinal symptoms? A comparison across disease states.
  Cohen E, Bolus R, Khanna D, Hays RD, Chang L, Melmed G, Khanna P, Spiegel B, Digestive Disease Week, 1/1/2013
• Gender and group differences in gastrointestinal symptom severity between IBS and IBD patients and the general population.
  Chang L, Bolus R, Melmed GY, Hays RD, Khanna D, Khanna P, Spiegel B, Digestive Disease Week, 1/1/2013
• Differences in Gastrointestinal Symptom Severity Between Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD) Patients and the General Population.
  Chang L, Bolus R, Melmed GY, Hays RD, Khanna D, Khanna P, Spiegel B, Digestive Disease Week, 1/1/2013
• Further validation of a novel patient educational booklet to enhance colonoscopy preparation: benefits in single-dose, but not split-dose preparations.
  Lee AD, Vu M, Fisher D, Modi R, Baek M, Spiegel B, Digestive Disease Week, 1/1/2013
• Low update of colorectal cancer screening among African-Americans in an integrated Veterans Affairs healthcare network.
  May F, Bromley E, Baek M, Yoon J, Cohen E, Lee A, Reid M, van Oijen MGH, Spiegel B, Digestive Disease Week, 1/1/2013
• A systematic review of patient, provider, and system barriers to colorectal cancer screening with colonoscopy in African-Americans.
  Bromley E, May F, Federer L, Spiegel B, van Oijen MGH, Digestive Disease Week, 1/1/2013
• Albumin Predicts Mortality and Other Outcomes in Acute Gastrointestinal Bleeding (GIB).
  Nordstrom C, Karsan S, Reid M, Spiegel B, Digestive Disease Week, 1/1/2013
• Post-diverticulitis irritable bowel syndrome.
  Cohen E, Fuller G, Bolus R, Modi R, Vu M, Shahedi K, Shah R, Atia M, Kurzbard N, Sheen V, Agarwal N, Kaneshiro M, Yen, Hodgkins P, Erder H, Spiegel B, Digestive Disease Week, 1/1/2012
• Significance of incidental diverticulosis found on colonoscopy: long-term risk of acute diverticulitis.
  Shahedi K, Fuller G, Bolus R, Cohen E, Vu M, Shah R, Agarwal N, Kaneshiro M, Atia M, Sheen V, Kurzbard N, van Oijen MGH, Yen L, Hodgkins P, Erder H, Spiegel B, Digestive Disease Week, 1/1/2012
• Comparing patients who show vs. no-show for outpatient colonoscopy: differences in cognitive, environmental, and demographic characteristics.
  Reynolds J, Wang H, Ocampo L, Kubomoto S, Thepyasuwan N, Baek M, Sharma G, Lee A, Liu J, Modi R, Levy A, Vu M, Poysophon P, Spiegel B, Digestive Disease Week, 1/1/2012
• Development of a novel "no-show" predictive overbooking algorithm for colonoscopy scheduling.
  Wang H, Thepysauwan N, Ocampo L, Kubomoto S, Lee A, Baek M, Sharma G, Liu J, Modi R, Levy A, Vu M, Snyder B, Poysophon P, Spiegel B, Digestive Disease Week, 1/1/2012
• Development of a nomogram for expected allocation in randomized controlled trials (RCTs): case study of treatment for hepatic encephalopathy.
  Paul N, Karsan S, Spiegel B, Digestive Disease Week, 1/1/2012
• Early Changes in Blood Urea Nitrogen Strongly Predict Mortality in Acute Gastrointestinal Bleeding.
  Karsan S, Nordstrom C, Huang E, Spiegel B, Digestive Disease Week, 1/1/2012
• What is the most cost-effective strategy for the management of chronic hepatic encephalopathy (HE)?
  Paul N, Spiegel B, Digestive Disease Week, 1/1/2012
• Direct costs and resource utilization for inpatient diverticulitis admissions.
  Spiegel B, Poysophon P, Snyder B, Agarwal N, Yen L, Hodgkins P, Cohen E, Vu M, Kurzbard N, Atia M, Sheen V, Kaneshiro M, Fuller G, Bolus R, American College of Gastroenterology Annual Meeting, 1/1/2011
• Clinical Presentation of Acute Diverticulitis: Most Patients Do Not Fulfill the Classic Triad of Pain, Fever, and Leukocytosis.
  Sheen V, Agarwal N, Poysophon P, Synder B, Kaneshiro M, Atia M, Yang J, Bolus R, Spiegel B, Digestive Disease Week, 1/1/2011
• Where Do Patients Report Diverticulitis Pain? -Abdominal "Pain Maps" Reveal Variable Presentations that Deviate from Classic Teaching.
  Kaneshiro M, Agarwal N, Poyshophon P, Synder B, Sheen V, Atia M, Yang J, Spiegel B, Digestive Disease Week, 1/1/2011
• Symnptom presentations of acute diverticulitis: one size does not fit all.
  Atia M, Agarwal N, Poysophon P, Snyder B, Sheen V, Kaneshiro M, Yang J, Spiegel B, Digestive Disease Week, 1/1/2011
• The effect of thrombocytopenia on outcomes in GI hemorrhage.
  Nordstrom C, Karsan S, Huang E, Singh I, Spiegel B, Digestive Disease Week, 1/1/2011
• Patient perceptions and understanding of the Bristol Stool Scale (BSS): results of cognitive de-briefing of IBS patients.
  Spiegel B, Bolus R, Sayuk G, Harris L, Lucak S, Esrailian E, Chey WD, Lembo A, Karsan H, Tillisch K, Talley J, Chang L, Digestive Disease Week, 1/1/2011
• Factors Analysis of Bowel Symptoms in IBS: Guidance for Patient Reported Outcome (PRO) Development.
  Spiegel B, Bolus R, Sayuk G, Harris L, Lucak S, Esrailian E, Chey WD, Lembo A, Karsan H, Tillisch K, Talley J, Chang L, Digestive Disease Week, 1/1/2011
• The cost-utility of screening for celiac disease in patients with unexplained aminotransferase elevations.
  Lewis S, Poysophon P, Spiegel B, Digestive Disease Week, 1/1/2011
• Less Experienced Endoscopists are More Likely to Report "Sub-Optimal" Bowel Preparation Quality vs. More Experienced Endoscopists.
  Wang H, Kubomoto S, Lee A, Ocampo L, Baek M, Sharma G, Liu J, Modi R, Thepyasuwan N, Levy A, Vu M, Sheen V, Atia M, Shahedi K, Snyder B, Poysophon P, Spiegel B, Digestive Disease Week, 1/1/2011
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Lectures

• Managing GI Bleeding 
  1/1/2016
• Health-e: Five Technologies that are Transforming Patient care. 
  1/1/2016
• Diagnostic Testing in IBS 
  San Diego, CA - 1/1/2016
• Systematic Review and Metaanalysis 
  1/1/2015
• Introduction to Cost-Effectiveness Analysis 
  1/1/2015
• Social Media Analytics 
  1/1/2015
• Electronic Health Records and Patient-Provider Portals 
  1/1/2015
• Introduction to mHealth 
  1/1/2015
• Irritable Bowel Syndrome 
  1/1/2015
• Colon Cancer Screening 
  1/1/2015
• Overview of basic biostatistics. 
  1/1/2015
• GERD and Barrett's Esophagus 
  1/1/2015
• Wearable Biosensors and Connected Health 
  1/1/2015
• My GI Health: Changing the Course to Gut Health Through Gut Feelings. 
  New York, NY - 1/1/2015
• Personalized Technologies: Self-Monitoring and Remote Sensor Technologies. 
  San Francisco, CA - 1/1/2015
• GI Quality Indicators. 
  Washington, DC - 1/1/2015
• Digital Health for the Gastroenterologist: What You Need to Know About Apps, Wearable Sensors and EHRs. 
  Washington, DC - 1/1/2015
• Predictive Overbooking Maximizes Endoscopy Utilization in an Outpatient Clinic. 
  Washington, DC - 1/1/2015
• Post-Operative Gastrointestinal (GI) Telemetry with a Wearable Acoustic Biosensor Distinguishes Ileus vs. Uneventful GI Recovery 
  Washington, DC - 1/1/2015
• Racial and Ethnic Disparities in Colonoscopy Utilization Among Individuals with a Family History of Colorectal Cancer 
  Washington, DC - 1/1/2015
• Social Medial Analytics and Digital Ethnography 
  Vancouver, Canada - 1/1/2015
• Applying Digital Health in the Clinical Enviornment 
  Boston, MA - 1/1/2015
• The Future of Gastroenterology Disease Monitoring: Mobile Health, Social Media, and Wearable Sensor Applications 
  Honolulu, HI - 1/1/2015
• Diverticular Disease: The New Chronic Disease 
  Honolulu, HI - 1/1/2015
• Culling the Wheat from the Chaff in Irritable Bowel Syndrome: When to Screen for Celiac Disease 
  Fort Lauderdale, TX - 1/1/2015
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Other

• Post-diverticulitis irritable bowel syndrome. 
  Cohen E, Fuller G, Bolus R, Modi R, Vu M, Shahedi K, Shah R, Atia M, Kurzbard N, Sheen V, Agarwal N, Kaneshiro M, Yen, Hodgkins P, Erder H, Spiegel B
  1/21/2013
• Chronically questioned about chronic constipation? 
  Spiegel, BMR; Horn JR; Mathis AS, Postgraduate Institute of Medicine Special Report
  1/1/2007
• The importance of the physician-patient relationship in functional gastrointestinal disorders. 
  Spiegel BMR, International Foundation for Functional Gastrointestinal Disorders (IFFGD) Patient Review Material
  1/1/2006
• Negotiating the therapeutic staircase in inflammatory bowel disease. 
  Spiegel BMR, The Gastroenterology Fellow
  1/1/2004
• Diagnosis and Management of Superior Mesenteric Artery Embolism. 
  Spiegel BMR, The Gastroenterology Fellow
  1/1/2004
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