BrentLKaneMD

Breast Cancer, Urologic Cancer

Radiation Oncology Site Director - UCSF Fresno Hematology/Oncology Fellowship Program; UCSF Assistant Clinical Professor

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Office
Community Cancer Institute
785 N. Medical Center Drive West
Clovis, CA 93611
Phone+1 559-387-1600

Fax+1 559-387-1677
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Summary

Born and raised in the Central Valley, Dr. Brent Kane is
proud to bring the most advanced radiation oncology
therapies and procedures to the region. A believer in the
team approach to cancer care, he has initiated and
developed many multi-disciplinary, comprehensive clinics at
Community Medical Centers. He is one of the main
physician contributors that developed and planned the
Community Cancer Institute. Dr. Kane continues to teach
the next generation of oncologists as an Assistant Clinical
Professor and Site Director of Radiation Oncology for the
UCSF Fresno Hematology/Oncology fellowship program.
“It is my privilege to provide radiation oncology to the
patients of the Central Valley. I collaborate with other
oncology specialists to devise the most appropriate, ethical
care for each patient. I emphasize the patient-centric
approach to tackling cancer, trying to realize how every
patient is not only affected by the disease and treatments, but
by the process as well.”

Radin Breast Center and Community Cancer Institute

When Clare Silveira felt a lump under her arm, she called the Marjorie E Radin Breast Care Center to move up her annual screening mammogram appointment. She was

Space OAR procedure for prostate cancer patients

The first SpaceOAR procedure in the Central Valley was performed in 2016 at Clovis Community Medical Center.

Targeting Lung Cancer

This is a mentor of mine - Doug Wong, MD. He is the visionary leader who brought most of the cancer care advances to the Central Valley including CyberKnife.

Education & Training

Loma Linda University Health Education ConsortiumResidency, Radiation Oncology, 1992 - 1995
University of California (San Francisco)/FresnoInternship, Internal Medicine, 1991 - 1992
Loma Linda University School of MedicineClass of 1991, MD

Certifications & Licensure

CA State Medical License 1992 - 2026
American Board of Radiology Radiation Oncology
American Board of Radiology Radiation Oncology Recertification

Awards, Honors, & Recognition

"Top Doctor" in Radiation Oncology Fresno Magazine’s Top Doctor in Radiation Oncology, 2008, 2011
"Top Performer", Officer Training School, Maxwell Air Force Base United States Air Force, 1995
Academic All-American, First Team - Football GTE/CoSIDA, 1986
Phi Kappa Phi Honor Society 1985
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Clinical Trials

Interstitial Brachytherapy With or Without External-Beam Radiation Therapy in Treating Patients With Prostate Cancer Start of enrollment: 2003 Jun 01
Completed
Phase 3
Radiation Therapy (WBI Versus PBI) in Treating Women Who Have Undergone Surgery For Ductal Carcinoma In Situ or Stage I or Stage II Breast Cancer Start of enrollment: 2005 Mar 01
Completed
Not Applicable
Ultrasound-Guided Implant Radiation Therapy in Treating Patients With Locally Recurrent Prostate Cancer Previously Treated With External-Beam Radiation Therapy Start of enrollment: 2007 May 01
Completed
Phase 2
Prostate Radiation Therapy or Short-Term Androgen Deprivation Therapy and Pelvic Lymph Node Radiation Therapy With or Without Prostate Radiation Therapy in Treating Patients With a Rising Prostate Specific Antigen (PSA) After Surgery for Prostate Cancer Start of enrollment: 2008 Feb 01
Active, not recruiting
Phase 3
Radiation Therapy Regimens in Treating Patients With Limited-Stage Small Cell Lung Cancer Receiving Cisplatin and Etoposide Start of enrollment: 2008 Mar 01
Active, not recruiting
Phase 3
Paclitaxel, Cisplatin, and Radiation Therapy With or Without Cetuximab in Treating Patients With Locally Advanced Esophageal Cancer Start of enrollment: 2008 Jun 01
Completed
Phase 3
Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy Start of enrollment: 2008 Nov 10
Active, not recruiting
Phase 3
Temozolomide and Radiation Therapy With or Without Bevacizumab in Treating Patients With Newly Diagnosed Glioblastoma Start of enrollment: 2009 Apr 15
Completed
Phase 3
Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed by the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery Start of enrollment: 2010 Apr 05
Active, not recruiting
Phase 3
Multi-Institutional Registry for Prostate Cancer Radiosurgery Start of enrollment: 2010 Jul 01
Recruiting
Early Surgery or Standard Palliative Therapy in Treating Patients With Stage IV Breast Cancer Start of enrollment: 2011 May 16
Completed
Not Applicable
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Publications & Presentations

PubMed

5 citations
High Dose "HDR-Like" Prostate SBRT: PSA 10-Year Results From a Mature, Multi-Institutional Clinical Trial.
Donald B Fuller, Tami Crabtree, Brent L Kane, Clinton A Medbery, Robert Pfeffer, James R Gray, Anuj Peddada, Trevor J Royce, Ronald C Chen> ;Frontiers in Oncology. 2022 Jan 1
42 citations
Phase 2 Multicenter Trial of Heterogeneous-dosing Stereotactic Body Radiotherapy for Low- and Intermediate-risk Prostate Cancer: 5-year Outcomes.
Donald B. Fuller, Aaron D. Falchook, Tami Crabtree, Brent L. Kane, Clinton A. Medbery, Kelly Underhill, J. R. Gray, Anuj V. Peddada, Ronald C. Chen> ;European Urology Oncology. 2018 Dec 1
18 citations
Patient and Dosimetric Predictors of Genitourinary and Bowel Quality of Life After Prostate SBRT: Secondary Analysis of a Multi-institutional Trial.
Kyle Wang, Ronald C. Chen, Brent L. Kane, Clinton A. Medbery, K. Underhill, J. R. Gray, Anuj V. Peddada, Donald B. Fuller> ;International Journal of Radiation Oncology, Biology, Physics. 2018 Dec 1
31 citations
Octreotide Acetate in Prevention of Chemoradiation-Induced Diarrhea in Anorectal Cancer: Randomized RTOG Trial 0315
Babu Zachariah, Clement K. Gwede, Jennifer L. James, Jaffer A. Ajani, Lisa J. Chin, David Donath, Seth A. Rosenthal, Brent L. Kane, Marvin Rotman, Lawrence Berk, Lisa ...> ;Journal of the National Cancer Institute. 2010 Apr 21
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Abstracts/Posters

Penile Bulb Dose Predicts Sexual Quality of Life after Prostate SBRT: Secondary Analysis of a Multi-Institutional Trial
Lui, K.P. & Wang, K. & Chen, R.C. & Kane, B.L. & III, C. & Jr, K. & Gray, J.R. & Peddada, A.V. & Fuller, Donald., International Journal of Radiation Oncology*Biology*Physics, Vol. 114 Issue 3 Supplement S54, Presented at Amer. Society for Radiation Oncology (ASTRO) Annual Meeting, November 2022, 11/1/2022
OC-0509 10-year outcome of ultrahypofractionated stereotactic RT from two multicenter prostate cancer trials
Meier, Robert and Bloch, D. and Chen, R. and Kane, B. and Henning, G. and Woodhouse, S. and Royce, T. and Cotrutz, Cristian and Fuller, Donald, Radiotherapy and Oncology, 8/1/2021
HDR-Like Prostate Stereotactic Body Radiotherapy: Evaluation of PSA kinetics, Clinical Relapse-free Survival and Adverse Events Beyond 5 years in a Multi-institutional...
Fuller, Donald & Kane, B.L. & Crabtree, T. & Iii, Clinton & Underhill, K. & Gray, J.R. & Peddada, A.…, International Journal of Radiation Oncology • Biology • Physics, 9/1/2019
Patient and Dosimetric Predictors of Genitourinary and Bowel Quality of Life after Prostate SBRT: Secondary Analysis of a Multi-institutional Trial
Wang, K. & Chen, R.C. & Kane, B.L. & Iii, Clinton & Underhill, K. & Gray, J.R. & Peddada, A.V. & Fuller, Donald., International Journal of Radiation Oncology • Biology • Physics, 11/1/2018
Erectile Function after High-Dose-Rate Brachytherapy-like Stereotactic Body Radiation Therapy for Organ-Confined Prostate Cancer
D.B. Fuller, B.L. Kane, K. Underhill, Jr, J.R. Gray, A.V. Peddada, and R.C. Chen, International Journal of Radiation Oncology • Biology • Physics, 11/1/2018
OC-0504: 5-year efficacy and quality of life outcomes of a multi-institutional HDR-Like prostate SBRT trial
D. Fuller , B. Kane , C. Medbery , K. Underhill , J. Gray , A. Peddada , R. Chen, Radiotherapy and Oncology; Presented at ESTRO 37, Barcelona, Spain, 4/20/2018
PSA Characteristics Post-Heterogeneous SBRT: Results From a Multi-institutional Phase 2 Trial
D.B. Fuller, B.L. Kane, C.A. Medbery III, K. Underhill Jr., J.R. Gray, A.V. Peddada, R.C. Chen, International Journal of Radiation Oncology • Biology • Physics, 10/1/2017
5-year outcomes from a prospective multi-institutional trial of heterogeneous dosing stereotactic body radiotherapy (SBRT) for low- and intermediate-risk prostate cancer.
Donald B. Fuller, Brent L. Kane, Clinton A. Medbery, Kelly Underhill, James R. Gray, Anuj Peddada, Ronald C. Chen, Journal of Clinical Oncology, 2/20/2017
Preliminary Report of Proton Radiation Therapy for Paraspinal Tumors
Kane, B., Slater, J., Radiology Vol. 197 (p) Nov. 1995, p. 263, Presented at RSNA ’95, 85th Annual Meeting: Chicago, IL, 11/28/1995
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Lectures

Update on Radiation Oncology (CME)
Fresno Madera Medical Society CME Cruise - 7/9/2019
2018 Cancer Treatment Updates: Breast - Radiation Oncology (CME)
Fresno, California - 12/6/2018
2018 Cancer Treatment Updates: Breast - Radiation Oncology (CME)
Hanford, California - 10/23/2018
2018 Cancer Treatment Updates: Breast - Radiation Oncology (CME)
Merced, California - 9/27/2018
Stereotactic Body Radiation Therapy (SBRT) for Early Stage Lung Cancer (CME)
UCSF, Fresno, California - 10/20/2012
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Committees

Vice-Chairman, Community Medical Centers Breast Program Leadership Committee 2021 - Present
Medical Director, Marjorie E. Radin Breast Center Board of Directors 2018 - Present
Member, Fresno-Madera Medical Society - Board of Governors 2018 - Present
State Captain, American Society for Radiation Oncology (ASTRO) Grassroots State Captain Initiative, Government Relations Council 2010 - Present
Treasurer/Secretary, Fresno Madera Medical Society Officers 2019 - 2019
Member, American Society for Radiation Oncology (ASTRO) Government Relations Committee 2015 - 2021
Delegate, California Medical Association 2009 - 2018
Member, American Society for Radiation Oncology (ASTRO) Congressional Relations Sub-committee, Government Relations Council 2007 - 2015
Medical Director, Marjorie E. Radin Breast Center Board of Medical Directors 2007 - 2013
Member, American Cancer Society; Fresno County Executive Board 2003 - 2006
Chairman, Fresno/Clovis Community Medical Centers Cancer Program 2001 - 2012

Professional Memberships

American Society for Radiation Oncology - ASTRO
Member
American Brachytherapy Society - ABS
Member
the Radiosurgical Society - RSS
Member
California Medical Association - CMA
Member
Fresno Madera Medical Society - FMMS
Member
Christian Medical and Dental Association - CMDA
Member

Hospital Affiliations

Community Regional Medical CenterFresno, California
Clovis Community Medical CenterClovis, California

External Links

Community Cancer Institutehttps://www.communitymedical.org/services/Community-Cancer-Institute
CyberKnife stereotactic radiosurgeryhttps://www.cyberknife.com
Prostate Brachytherapy - "Seed Implants"https://www.americanbrachytherapy.org/resources/prostate-seeds/