BretChristopherMobleyMD

PubMed

• Arteriolar degeneration and stiffness in cerebral amyloid angiopathy are linked to β-amyloid deposition and lysyl oxidase.
  Lissa Ventura-Antunes, Alex Nackenoff, Wilber Romero-Fernandez, Allison M Bosworth, Alex Prusky, Emmeline Wang, Cristian Carvajal-Tapia, Alena Shostak, Jose Maldonado,...> ;Biorxiv. 2024 Apr 17
• IL-8 Instructs Macrophage Identity in Lateral Ventricle Contacting Glioblastoma.
  Stephanie Medina, Asa A Brockman, Claire E Cross, Madeline J Hayes, Kyle D Weaver, Rebecca A Ihrie, Reid C Thompson, Jonathan M Irish, Bret C Mobley, Akshitkumar M Mis...> ;Biorxiv. 2024 Mar 30
• Progressive leukoencephalopathy as a manifestation of primary angiitis of the central nervous system: case report and review of the literature.
  Adam J Stark, Bret C Mobley, James E Eaton> ;Journal of Neurology. 2024 Mar 13
• AXL/WRNIP1 Mediates Replication Stress Response and Promotes Therapy Resistance and Metachronous Metastasis in HER2+ Breast Cancer.
  Marquez-Palencia, M., Reza Herrera, L., Parida, P., Ghosh, S., Kim, K., Das, N., Gonzalez-Ericsson, P., Sanders, M., Mobley, B., Diegeler, S., Aguilera, T., Peng, Y., ...> ;Cancer Research. 2024 Mar 4
• Pembrolizumab alters the tumor immune landscape in a patient with dMMR glioblastoma.
  Bartkowiak, T., Brockman, A., Moots, P., Merrell, R., Thompson, R., Ihrie, R., Mobley, B., Harmsen, H., Johnson, D., Puduvalli, V.> ;Medrxiv. 2023 Dec 26
• 1 citations
  Human Heart Failure Alters Mitochondria and Fiber 3D Structure Triggering Metabolic Shifts.
  Zer Vue, Peter T Ajayi, Kit Neikirk, Alexandria C Murphy, Praveena Prasad, Brenita C Jenkins, Larry Vang, Edgar Garza-Lopez, Margaret Mungai, Andrea G Marshall, Heathe...> ;Biorxiv. 2023 Dec 14
• 3D Mitochondrial Structure in Aging Human Skeletal Muscle: Insights into MFN-2 Mediated Changes.
  Estevão Scudese, Zer Vue, Prassana Katti, Andrea Marshall, Larry Vang, Edgar Garza López, Kit Neikirk, Dominique Stephens, Duane D Hall, Rahmati Rostami, Jian-Qiang Sh...> ;Biorxiv. 2023 Dec 14
• 3 citations
  3D reconstruction of murine mitochondria reveals changes in structure during aging linked to the MICOS complex.
  Zer Vue, Edgar Garza-Lopez, Kit Neikirk, Prasanna Katti, Larry Vang, Heather Beasley, Jianqiang Shao, Andrea G Marshall, Amber Crabtree, Alexandria C Murphy, Brenita C...> ;Aging Cell. 2023 Dec 1
• 12 citations
  Three-dimensional mitochondria reconstructions of murine cardiac muscle changes in size across aging.
  Zer Vue, Kit Neikirk, Larry Vang, Edgar Garza-Lopez, Trace A Christensen, Jianqiang Shao, Jacob Lam, Heather K Beasley, Andrea G Marshall, Amber Crabtree, Josephs Anud...> ;American Journal of Physiology. Heart and Circulatory Physiology. 2023 Nov 1
• Molecular profiling identifies at least 3 distinct types of posttransplant lymphoproliferative disorder involving the CNS.
  Ekin Guney, Calixto-Hope G Lucas, Kunwar Singh, Melike Pekmezci, Sebastian Fernandez-Pol, Kanish Mirchia, Angus Toland, Hannes Vogel, Serguei Bannykh, Kristian T Schaf...> ;Blood Advances. 2023 Jul 11
• 2 citations
  Clinical utility of whole-genome DNA methylation profiling as a primary molecular diagnostic assay for central nervous system tumors-A prospective study and guidelines...
  Galbraith, K., Vasudevaraja, V., Serrano, J., Shen, G., Tran, I., Abdallat, N., Wen, M., Patel, S., Movahed-Ezazi, M., Faustin, A., Spino-Keeton, M., Roberts, L., Malo...> ;Neuro-Oncology Advances. 2023 Jun 26
• 8 citations
  Limiting mitochondrial plasticity by targeting DRP1 induces metabolic reprogramming and reduces breast cancer brain metastases.
  Pravat Kumar Parida, Mauricio Marquez-Palencia, Suvranil Ghosh, Nitin Khandelwal, Kangsan Kim, Vidhya Nair, Xiao-Zheng Liu, Hieu S Vu, Lauren G Zacharias, Paula I Gonz...> ;Nature Cancer. 2023 Jun 1
• 1 citations
  An immunosuppressed microenvironment distinguishes lateral ventricle-contacting glioblastomas.
  Todd Bartkowiak, Sierra M Lima, Madeline J Hayes, Akshitkumar M Mistry, Asa A Brockman, Justine Sinnaeve, Nalin Leelatian, Caroline E Roe, Bret C Mobley, Silky Chotai,...> ;JCI Insight. 2023 Jun 22
• 2 citations
  Author Correction: Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes.
  Norman L Lehman, Nathalie Spassky, Müge Sak, Amy Webb, Cory T Zumbar, Aisulu Usubalieva, Khaled J Alkhateeb, Joseph P McElroy, Kirsteen H Maclean, Paolo Fadda, Tom Liu...> ;Nature Communications. 2023 Jan 31
• 3 citations
  Primary Intracranial Sarcoma, DICER1-Mutant Presenting as a Pineal Region Tumor Mimicking Pineoblastoma: Case Report and Review of the Literature.
  Nalin Leelatian, James Goss, Devang Pastakia, Michael C Dewan, Matija Snuderl, Bret C Mobley> ;Journal of Neuropathology and Experimental Neurology. 2022 Aug 16
• 1 citations
  Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes.
  Norman L Lehman, Nathalie Spassky, Müge Sak, Amy Webb, Cory T Zumbar, Aisulu Usubalieva, Khaled J Alkhateeb, Joseph P McElroy, Kirsteen H Maclean, Paolo Fadda, Tom Liu...> ;Nature Communications. 2022 Apr 19
• Phase I Study of High-Dose L-methylfolate in Combination with Temozolomide and Bevacizumab in Recurrent IDH wild-type High-Grade Glioma.
  Lucas A Salas, Thomas G Stewart, Bret C Mobley, Chengwei Peng, Jing Liu, Sudan N Loganathan, Jialiang Wang, Yanjun Ma, Mitchell S Berger, Devin Absher, Yang Hu, Paul L...> ;Cancer Research Communications. 2022 Jan 1
• 7 citations
  Histological Studies of the Ventricular–Subventricular Zone as Neural Stem Cell and Glioma Stem Cell Niche:
  Asa A. Brockman, Bret C. Mobley, Rebecca A. Ihrie> ;The Journal of Histochemistry and Cytochemistry. 2021 Jul 26
• 6 citations
  Impact of postoperative dexamethasone on survival, steroid dependency, and infections in newly diagnosed glioblastoma patients.
  Akshitkumar M. Mistry, Sumeeth V. Jonathan, Meredith A Monsour, Bret C. Mobley, Stephen W. Clark, Paul L. Moots> ;Neuro-Oncology Practice. 2021 Jun 23
• 19 citations
  PLD3 is a neuronal lysosomal phospholipase D associated with β-amyloid plaques and cognitive function in Alzheimer's disease.
  Alex Nackenoff, Timothy J. Hohman, Sarah M. Neuner, Carolyn Akers, Nicole C. Weitzel, Alena Shostak, Shawn M. Ferguson, Bret C. Mobley, David A. Bennett, Julie A. Schn...> ;Plos Genetics. 2021 Apr 8
• 3 citations
  Prognostic relevance of CSF and peri-tumoral edema volumes in glioblastoma
  Nishit Mummareddy, Sanjana Salwi, Nishant Ganesh Kumar, Zhiguo Zhao, Fei Ye, Chi H. Le, Bret C. Mobley, Reid C. Thompson, Lola B. Chambless, Akshitkumar M. Mistry> ;Journal of Clinical Neuroscience. 2021 Feb 1
• Sustained response to erlotinib and rapamycin in a patient with pediatric anaplastic oligodendroglioma.
  Laura C. Geben, Bret C. Mobley, Asa A. Brockman, Devang Pastakia, Rob Naftel, Rebecca A. Ihrie, Adam J. Esbenshade> ;Pediatric Blood & Cancer. 2021 Jan 1
• 14 citations
  Unsupervised machine learning reveals risk stratifying glioblastoma tumor cells
  Nalin Leelatian, Justine Sinnaeve, Akshitkumar M. Mistry, Sierra Barone, Asa A. Brockman, Kirsten E. Diggins, Allison R. Greenplate, Kyle D. Weaver, Reid C. Thompson, ...> ;Elife. 2020 Jun 23
• 1 citations
  Pituitary Apoplexy During Hematopoietic Cell Transplantation.
  Aneri Patel, Bret C. Mobley, Madan Jagasia, Kassim Adetola, Michael Byrne, Bhagirathbhai Dholaria> ;Clinical Lymphoma, Myeloma & Leukemia. 2020 May 26
• 42 citations
  Targeting MYCN-expressing triple-negative breast cancer with BET and MEK inhibitors.
  Johanna M. Schafer, Brian D. Lehmann, Paula I. Gonzalez-Ericsson, Clayton B. Marshall, J. Scott Beeler, Lindsay N. Redman, Hailing Jin, Violeta Sanchez, Matthew C. Stu...> ;Science Translational Medicine. 2020 Mar 11
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Journal Articles

• Diagnostic utility of PHOX2B in primary and treated neuroblastoma and in neuroblastoma metastatic to the bone marrow  
  Hata JL, Correa H, Krishnan C, Esbenshade AJ, Black JO, Chung DH, Mobley BC, Arch Pathol Lab Med, 1/1/2015
• LC3 and p62 as diagnostic markers of drug-induced autophagic vacuolar cardiomyopathy: a study of 3 cases  
  Daniels BH, McComb RD, Mobley BC, Gultekin SH, Lee HS, Margeta M, Am J Surg Pathol, 1/1/2013
• Peripheral primitive neuroectodermal tumor/Ewing's sarcoma of the craniospinal vault: case reports and review  
  Mobley BC, Roulston D, Shah GV, Bijwaard KE, and McKeever PE, Human Pathology, 1/1/2006
• IGF-I prevents glutamate-induced motor neuron programmed cell death  
  Vincent AM, Mobley BC, Hiller A, and Feldman EL, Neurobiology of Disease, 1/1/2004
• Delivery of an adenoviral vector to the crushed recurrent laryngeal nerve  
  Rubin A, Mobley B, Hogikyan N, Bell K, Sullivan K, Boulis N, and Feldman E, 1/1/2003
• Diffusion-Weighted MRI: Distinction of Skull Base Chordoma From Chondrosarcoma  
  Yeom KW, Lober RM, Mobley BC, Harsh G, Vogel H, Allagio R, Pearson M, Edwards MS, Fischbein NJ, Am J Neuroradiol, 1/1./2012
• InsR/IGF1R pathway mediates resistance to EGFR inhibitors in glioblastoma  
  Ma Y, Tang N, Thompson RC, Mobley B, Clark SW, Sarkaria JN, Wang J, Clin Cancer Res, 1/11/2015
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Books/Book Chapters

• Textbook of Uncommon Cancer 
  Chapter: Glioma and Other Neuroepithelial Neoplasms 
  Page 767.0 - 794.0Palka, K., Cooper, M., Perkins, S., Mobley, B., Sills A.K. Jr, Moots, P.L.Editors: Raghavan, D., Blanke, C., Johnson, D.H., Moots, P.L., Reaman, G., Rose, P., Sekeres, M..John Wiley & Sons, West Sussex, EnglandEdition 4th,2012

Abstracts/Posters

• p75NTR regulates the maintenance of sympathetic neural stem cells
  Bret Mobley and Bruce Carter, NGF Conference, 1/1/2012
• Remote gene delivery: a potential new therapy for neuropathy
  Nicholas Boulis, Bret Mobley, Aaron Noordmans, Debbie Song, and Eva L. Feldman, 126th Annual Meeting of the American Neurologic Association, 1/1/2001
• Endothelin-1 and 3 inhibit neurogenesis of post migratory neural crest stem cells from rat sciatic nerve and small intestine; they promote survival of sciatic nerve cells
  Bret Mobley and Sean J. Morrison, The University of Michigan Student Biomedical Research Forum, 1/1/2000

Other

• Molecular Profiling of Glioma 
  Abel, T.W., K. Aldape, S. Clark, C. Vnencak-Jones, B. Mobley, My Cancer Genome
  http://www.mycancergenome.org/content/disease/glioma/
  1/1/2014