BrettAndrewMcCrayMDPhD

Neurology • Ann Arbor, MI

Neurology resident, Partners Neurology

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Office
109 Zina Pitcher Place
4015 BSRB
Ann Arbor, MI 48109
Phone+1 734-764-8425

Fax+1 734-763-7686
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Education & Training

Brigham and Women's Hospital/Massachusetts General Hospital/Harvard Medical SchoolResidency, Neurology, 2012 - 2015
Brigham and Women's HospitalInternship, Internal Medicine, 2011 - 2012
Perelman School of Medicine at the University of PennsylvaniaClass of 2011

Certifications & Licensure

MI State Medical License 2023 - 2026
MD State Medical License 2016 - 2023
PA State Medical License 2015 - 2016
MA State Medical License 2011 - 2015
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

Inductee Alpha Omega Alpha Honor Medical Society, 2011

Publications & Presentations

PubMed

10 citations
Crosstalk between regulatory elements in disordered TRPV4 N-terminus modulates lipid-dependent channel activity.
Benedikt Goretzki, Christoph Wiedemann, Brett A McCray, Stefan L Schäfer, Jasmin Jansen, Frederike Tebbe, Sarah-Ana Mitrovic, Julia Nöth, Ainara Claveras Cabezudo, Jac...> ;Nature Communications. 2023 Jul 13
9 citations
TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease.
Do Hoon Kwon, Feng Zhang, Brett A McCray, Shasha Feng, Meha Kumar, Jeremy M Sullivan, Wonpil Im, Charlotte J Sumner, Seok-Yong Lee> ;Nature Communications. 2023 Jun 23
1 citations
Neuropathy due to bi-allelic SH3TC2 variants: genotype-phenotype correlation and natural history.
Tyler Rehbein, Tong Tong Wu, Simona Treidler, Davide Pareyson, Richard Lewis, Sabrina W Yum, Brett A McCray, Sindhu Ramchandren, Joshua Burns, Jun Li, Richard S Finkel...> ;Brain. 2023 Sep 1
12 citations
TRPV4: A trigger of pathological RhoA activation in neurological disease.
Anna M Bagnell, Charlotte J Sumner, Brett A McCray> ;Bioessays. 2022 Jun 1
4 citations
Multiubiquitination of TRPV4 reduces channel activity independent of surface localization.
William H Aisenberg, Brett A McCray, Jeremy M Sullivan, Erika Diehl, Lauren R DeVine, Jonathan Alevy, Anna M Bagnell, Patrice Carr, Jack K Donohue, Benedikt Goretzki, ...> ;The Journal of Biological Chemistry. 2022 Apr 1
6 citations
TRPV4 mutations causing mixed neuropathy and skeletal phenotypes result in severe gain of function.
Arens Taga, Benedikt Goretzki, Thomas Q Gallagher, Ann Ritter, Amy Harper, Thomas O Crawford, Ute A Hellmich, Charlotte J Sumner, Brett A McCray, Peyton, M.> ;Annals of Clinical and Translational Neurology. 2022 Mar 1
20 citations
Axonal Charcot-Marie-Tooth Disease: from Common Pathogenic Mechanisms to Emerging Treatment Opportunities.
Brett A. McCray, Steven S. Scherer> ;Neurotherapeutics. 2021 Oct 4
19 citations
Neuropathy-causing TRPV4 mutations disrupt TRPV4-RhoA interactions and impair neurite extension.
Brett A. McCray, Erika Diehl, Jeremy M. Sullivan, William H. Aisenberg, Nicholas W. Zaccor, Alexander R. Lau, Dominick J. Rich, Benedikt Goretzki, Ute A. Hellmich, Tho...> ;Nature Communications. 2021 Mar 4
37 citations
TRPV4 disrupts mitochondrial transport and causes axonal degeneration via a CaMKII-dependent elevation of intracellular Ca 2+
Brian M. Woolums, Brett A. McCray, Hyun Sung, Masashi Tabuchi, Jeremy M. Sullivan, Kendra Takle Ruppell, Yunpeng Yang, Catherine Mamah, William H. Aisenberg, Pamela C....> ;Nature Communications. 2020 May 29
Fifteen-year longitudinal follow-up of a patient with severe early-onset Charcot-Marie-Tooth disease type 2A.
Brett A. McCray, William Hurst, Thomas O. Crawford, Thomas E. Lloyd> ;Muscle & Nerve. 2018 May 1
2 citations
Novel hemizygous nonsense mutation in DRP2 is associated with inherited neuropathy
Ricardo H. Roda, Brett A. McCray, Christopher J. Klein, Ahmet Hoke> ;Neurology. Genetics. 2018 Feb 1
Tongue infarction due to giant cell arteritis
Altaf Saadi, Brett A. McCray, Erik R. Ensrud, Sashank Prasad> ;Practical Neurology. 2016 Jun 1
3 citations
Clinical Reasoning: A 57-year-old woman who developed acute amnesia following fever and upper respiratory symptoms
Brett A. McCray, Deborah Forst, Jenelle A. Jindal, Galen V. Henderson> ;Neurology. 2015 Apr 7
41 citations
Network Analyses Reveal Novel Aspects of ALS Pathogenesis
Mario Sanhueza, Andrea Chai, Colin Smith, Brett A. McCray, T. Ian Simpson, J. Paul Taylor, Giuseppa Pennetta> ;Plos Genetics. 2015 Mar 31
19 citations
Isolated cerebral mucormycosis of the basal ganglia
Athar N. Malik, Wenya Linda Bi, Brett A. McCray, Malak Abedalthagafi, Henrikas Vaitkevicius, Ian F. Dunn> ;Clinical Neurology and Neurosurgery. 2014 Sep 1
88 citations
Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation
Brett A. McCray, Emmanuel Skordalakes, J. Paul Taylor> ;Human Molecular Genetics. 2010 Mar 15
55 citations
Selective accumulation of aggregation-prone proteasome substrates in response to proteotoxic stress.
Florian A. Salomons, Victoria Menendez-Benito, Claudia Böttcher, Brett A. McCray, J. Paul Taylor, Nico P. Dantuma> ;Molecular and Cellular Biology. 2009 Apr 1
73 citations
The role of autophagy in age-related neurodegeneration.
Brett A. McCray, J. Paul Taylor> ;Neuro-Signals. 2008 Jan 1
956 citations
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
Udai Bhan Pandey, Zhiping Nie, Yakup Batlevi, Brett A. McCray, Gillian P. Ritson, Natalia B. Nedelsky, Stephanie L. Schwartz, Nicholas A. Diprospero, Melanie Knight, O...> ;Nature. 2007 Jun 14
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