BrianDHudsonMD

PubMed

• 4 citations
  Identification of novel competing β2AR phospho-extracellular signal regulated kinase 1/2 signaling pathways in human trabecular meshwork cells.
  Brian D. Hudson, Melanie E. M. Kelly> ;Journal of Ocular Pharmacology and Therapeutics. 2012 Feb 7
• 66 citations
  Mechanism and function of Drosophila capa GPCR: a desiccation stress-responsive receptor with functional homology to human neuromedinU receptor.
  Selim Terhzaz, Pablo Cabrero, Joris H. Robben, Jonathan C. Radford, Brian D. Hudson, Graeme Milligan, Julian A. T. Dow, Shireen A. Davies> ;Plos One. 2012 Jan 11
• 28 citations
  Indirect Sympatholytic Actions at β-Adrenoceptors Account for the Ocular Hypotensive Actions of Cannabinoid Receptor Agonists
  Brian D. Hudson, Meggie Beazley, Anna-Maria Szczesniak, Alex Straiker, Melanie E. M. Kelly> ;The Journal of Pharmacology and Experimental Therapeutics. 2011 Dec 1
• 8 citations
  Conformation-dependent QSPR models: logPOW.
  Markus Muehlbacher, Ahmed M. El Kerdawy, Christian Kramer, Brian D. Hudson, Timothy Clark> ;Journal of Chemical Information and Modeling. 2011 Aug 29
• 65 citations
  Extracellular Loop 2 of the Free Fatty Acid Receptor 2 Mediates Allosterism of a Phenylacetamide Ago-Allosteric Modulator
  Nicola J. Smith, Richard J. Ward, Leigh A. Stoddart, Brian D. Hudson, Evi Kostenis, Trond Ulven, Joanne C. Morris, Christian Tränkle, Irina G. Tikhonova, David R. Adam...> ;Molecular Pharmacology. 2011 Jul 1
• 86 citations
  Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3
  Johannes Schmidt, Nicola J. Smith, Elisabeth Christiansen, Irina G. Tikhonova, Manuel Grundmann, Brian D. Hudson, Richard J. Ward, Christel Drewke, Graeme Milligan, Ev...> ;The Journal of Biological Chemistry. 2011 Mar 25
• 43 citations
  Experimental Challenges to Targeting Poorly Characterized GPCRs: Uncovering the Therapeutic Potential for Free Fatty Acid Receptors
  Brian D. Hudson, Nicola J. Smith, Graeme Milligan> ;Advances in Pharmacology. 2011 Jan 1
• 79 citations
  Identification of novel species-selective agonists of the G-protein-coupled receptor GPR35 that promote recruitment of β-arrestin-2 and activate Gα13
  Laura Jenkins, José Brea, Nicola J. Smith, Brian D. Hudson, Graeme Reilly, Nia J. Bryant, Marián Castro, María Isabel Loza, Graeme Milligan> ;The Biochemical Journal. 2010 Dec 15
• 64 citations
  Physical and functional interaction between CB1 cannabinoid receptors and β2-adrenoceptors
  Brian D. Hudson, Terence E. Hébert, Melanie E. M. Kelly> ;British Journal of Pharmacology. 2010 Jun 1
• 77 citations
  LIGAND AND HETERODIMER DIRECTED SIGNALING OF THE CB1 CANNABINOID RECEPTOR
  Brian D. Hudson, Terence E. Hébert, Melanie E. M. Kelly> ;Molecular Pharmacology. 2010 Jan 1
• 3 citations
  Vicinity analysis: a methodology for the identification of similar protein active sites
  A. McGready, A. Stevens, M. Lipkin, Brian D. Hudson, David C. Whitley, Martyn G. Ford> ;Journal of Molecular Modeling. 2009 May 1
• 4 citations
  QSAR studies using the parashift system
  David J. Livingstone, Timothy Clark, Martyn G. Ford, Brian D. Hudson, David C. Whitley> ;SAR and QSAR in Environmental Research. 2008 Apr 1
• 4 citations
  Pattern recognition based on color-coded quantum mechanical surfaces for molecular alignment.
  Brian D. Hudson, David C. Whitley, Martyn G. Ford, Martin T. Swain, Jonathan W. Essex> ;Journal of Molecular Modeling. 2008 Jan 1
• The extraction of information and knowledge from trained neural networks.
  David J. Livingstone, Antony Browne, Raymond Crichton, Brian D. Hudson, David C. Whitley, Martyn G. Ford> ;Methods in Molecular Biology. 2008 Jan 1
• 53 citations
  Toward high throughput 3D virtual screening using spherical harmonic surface representations
  Lazaros Mavridis, Brian D. Hudson, David W. Ritchie> ;Journal of Chemical Information and Modeling. 2007 Sep 7
• 4 citations
  A Computer-Aided Drug Discovery System for Chemistry Teaching
  Robert J. Gledhill, Sarah Kent, Brian D. Hudson, W. Graham Richards, Jonathan W. Essex, Jeremy G. Frey> ;Journal of Chemical Information and Modeling. 2006 Jan 21
• 10 citations
  DASH: a novel analysis method for molecular dynamics simulation data. Analysis of ligands of PPAR-γ
  David W. Salt, Brian D. Hudson, Lee Banting, Matthew J Ellis, Martyn G. Ford> ;Journal of Medicinal Chemistry. 2005 May 5
• 37 citations
  A Consensus Neural Network-Based Technique for Discriminating Soluble and Poorly Soluble Compounds
  David T. Manallack, Benjamin G Tehan, Emanuela Gancia, Brian D Hudson, Martyn G Ford, David J. Livingstone, David C. Whitley, William R. Pitt> ;Journal of Chemical Information and Computer Sciences. 2003 Jan 14
• 5 citations
  QSAR studies of the pyrethroid insecticides. Part 3. A putative pharmacophore derived using methodology based on molecular dynamics and hierarchical cluster analysis.
  Martyn G. Ford, Neil E. Hoare, Brian D. Hudson, Thomas G. Nevell, Lee Banting> ;Journal of Molecular Graphics & Modelling. 2002 Aug 1
• 7 citations
  Structure-activity relationships of pyrethroid insecticides. Part 2. The use of molecular dynamics for conformation searching and average parameter calculation.
  Brian D. Hudson, Ashley R. George, Martyn G. Ford, David J. Livingstone> ;Journal of Computer-Aided Molecular Design. 1992 Apr 1
• The angiotensin IV analog Nle-Tyr-Leu-psi-(CH2-NH2)3-4-His-Pro-Phe (norleual) can act as a hepatocyte growth factor/c-Met inhibitor.
  Yamamoto, B. J., Elias, P. D., Masino, J. A., Hudson, B. D., McCoy, A. T., Anderson, Z. J., Varnum, M. D., Sardinia, M. F., Wright, J. W., Harding, J. W.> ;J Pharmacol Exp Ther. 2010 Apr
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