BrianJNickoloffMD

PubMed

• 114 citations
  Characterization of the cytokine storm reflects hyperinflammatory endothelial dysfunction in COVID-19.
  Jonathan T. Sims, Venkatesh Krishnan, Ching Yun Chang, Sarah M. Engle, Giacomo Casalini, George H. Rodgers, Nicoletta Bivi, Brian J. Nickoloff, Robert J. Konrad, Steph...> ;The Journal of Allergy and Clinical Immunology. 2021 Jan 1
• 185 citations
  Mechanism of baricitinib supports artificial intelligence-predicted testing in COVID-19 patients.
  Justin Stebbing, Venkatesh Krishnan, Stephanie de Bono, Silvia Ottaviani, Giacomo Casalini, Peter J. Richardson, Vanessa Monteil, Volker M. Lauschke, Ali Mirazimi, Son...> ;EMBO Molecular Medicine. 2020 Aug 7
• 30 citations
  Assessment and Clinical Relevance of Serum IL-19 Levels in Psoriasis and Atopic Dermatitis Using a Sensitive and Specific Novel Immunoassay
  Robert J. Konrad, Richard E. Higgs, George H. Rodgers, Wenyu Ming, Yue-Wei Qian, Nicoletta Bivi, Justin K. Mack, Robert W. Siegel, Brian J. Nickoloff> ;Scientific Reports. 2019 Mar 26
• 22 citations
  Loss of miR-204 expression is a key event in melanoma.
  Marco Galasso, Carl Morrison, Linda Minotti, Fabio Corrà, Carlotta Zerbinati, Chiara Agnoletto, Federica Baldassari, Matteo Fassan, Armando Bartolazzi, Andrea Vecchion...> ;Molecular Cancer. 2018 Mar 9
• 220 citations
  Baricitinib in adult patients with moderate-to-severe atopic dermatitis: a phase 2 parallel, double-blinded, randomized placebo-controlled multiple-dose study
  Emma Guttman-Yassky, Jonathan I. Silverberg, Osamu Nemoto, Seth Forman, August Wilke, Randy Prescilla, Amparo de la Peña, Fabio P. Nunes, Jonathan Janes, Margaret Gama...> ;Journal of the American Academy of Dermatology. 2018 Feb 2
• 111 citations
  Phase 3 Trials of Ixekizumab in Moderate-to-Severe Plaque Psoriasis.
  Kenneth B Gordon, Andrew Blauvelt, Kim A Papp, Richard G Langley, Thomas Luger, Mamitaro Ohtsuki, Kristian Reich, David Amato, Susan G Ball, Daniel K Braun, Gregory S ...> ;The New England Journal of Medicine. 2016 Jul 28
• 5 citations
  Molecular Insights into Fully Human and Humanized Monoclonal Antibodies: What are the Differences and Should Dermatologists Care?
  Lotus Mallbris, Julian Davies, Andrew L. Glasebrook, Ying Tang, Wolfgang Glaesner, Brian J. Nickoloff> ;The Journal of Clinical and Aesthetic Dermatology. 2016 Jul 1
• 3 citations
  Ixekizumab for psoriasis – Authors' reply
  Christopher E.M. Griffiths, Kim A. Papp, Susan Ball, Brian J. Nickoloff> ;Lancet. 2016 Jan 16
• 617 citations
  Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials
  Christopher E.M. Griffiths, Kristian Reich, Mark Lebwohl, Peter C.M. van de Kerkhof, Carle Paul, Alan Menter, Gregory S Cameron, J. Erickson, L. Zhang, Roberta J. Secr...> ;Lancet. 2015 Aug 8
• Psoriasis: The Poster Child for Bench-to-bedside Translational Medicine
  Lotus Mallbris, Brian J. Nickoloff> ;The Journal of Clinical and Aesthetic Dermatology. 2015 Jul 1
• 22 citations
  Melanoma patient derived xenografts acquire distinct Vemurafenib resistance mechanisms
  David J. Monsma, David Cherba, Emily Eugster, Dawna Dylewski, Paula T Davidson, Chelsea A Peterson, Andrew Borgman, Mary E. Winn, Karl Dykema, Craig P. Webb, Jeffrey P...> ;American Journal of Cancer Research. 2015 Jan 1
• 16 citations
  Melanoma genotypes and phenotypes get personal
  Jose M. Pimiento, Eileen M Larkin, Keiran S.M. Smalley, Ginger L Wiersma, Noel R. Monks, Inna V. Fedorenko, Chelsea A Peterson, Brian J. Nickoloff> ;Laboratory Investigation; a Journal of Technical Methods and Pathology. 2013 Aug 1
• 21 citations
  Pharmacologic Inhibition of MEK Signaling Prevents Growth of Canine Hemangiosarcoma
  Nicholas J. Andersen, Brian J. Nickoloff, Karl Dykema, Elissa Boguslawski, Roman Krivochenitser, Roe Froman, Michelle J. Dawes, Laurence H. Baker, Dafydd G. Thomas, De...> ;Molecular Cancer Therapeutics. 2013 Jun 26
• 1 citations
  Hepatocyte growth factor in the neighborhood reverses resistance to BRAF inhibitor in melanoma
  Brian J. Nickoloff, George Vande Woude> ;Pigment Cell & Melanoma Research. 2012 Nov 1
• 53 citations
  Genomic characterization of explant tumorgraft models derived from fresh patient tumor tissue.
  David J. Monsma, Noel R. Monks, David Cherba, Dawna Dylewski, Emily Eugster, Hailey Jahn, Sujata Srikanth, Stephanie B. Scott, Patrick J. Richardson, Robin E. Everts, ...> ;Journal of Translational Medicine. 2012 Jun 18
• 29 citations
  Specifically targeting ERK1 or ERK2 kills melanoma cells.
  Jianzhong Qin, Hong Xin, Brian J. Nickoloff> ;Journal of Translational Medicine. 2012 Jan 25
• 253 citations
  Identification of a Novel Proinflammatory Human Skin-Homing Vγ9Vδ2 T Cell Subset with a Potential Role in Psoriasis
  Ute Laggner, Paola Di Meglio, Gayathri K. Perera, Christian Hundhausen, Katie E. Lacy, Niwa Ali, Catherine H. Smith, Adrian Hayday, Brian J. Nickoloff, Frank O. Nestle> ;Journal of Immunology. 2011 Sep 1
• 107 citations
  Notch Signaling Regulates Mouse and Human Th17 Differentiation
  Shilpa Keerthivasan, Reem Suleiman, Rebecca G. Lawlor, Justine E. Roderick, Tonya C. Bates, Lisa M. Minter, Juan Anguita, Ignacio J. Juncadella, Brian J. Nickoloff, I....> ;Journal of Immunology. 2011 Jul 15
• 160 citations
  Cutting Edge: A Critical Functional Role for IL-23 in Psoriasis
  G Tonel, Curdin Conrad, Ute Laggner, Paola Di Meglio, K. Grys, Terrill K. McClanahan, Wendy M. Blumenschein, Jian-Zhong Qin, Hong Xin, Elizabeth Oldham, Robert A. Kast...> ;Journal of Immunology. 2010 Nov 15
• 15 citations
  2-deoxyglucose sensitizes melanoma cells to TRAIL-induced apoptosis which is reduced by mannose.
  J.-Z. Qin, H. Xin, Brian J. Nickoloff> ;Biochemical and Biophysical Research Communications. 2010 Oct 15
• 32 citations
  Loss of Inositol Polyphosphate 5-Phosphatase Is an Early Event in Development of Cutaneous Squamous Cell Carcinoma
  Aleksandar Sekulic, Su Y. Kim, Galen Hostetter, Stephanie Savage, Janine G. Einspahr, Anil Prasad, Paul Sagerman, Clara Curiel-Lewandrowski, Robert S. Krouse, G. Timot...> ;Cancer Prevention Research. 2010 Sep 28
• 24 citations
  Targeting glutamine metabolism sensitizes melanoma cells to TRAIL-induced death.
  J.-Z. Qin, H. Xin, Brian J. Nickoloff> ;Biochemical and Biophysical Research Communications. 2010 Jul 16
• 45 citations
  3-Bromopyruvate induces necrotic cell death in sensitive melanoma cell lines
  Jingdong Qin, H. Xin, Brian J. Nickoloff> ;Biochemical and Biophysical Research Communications. 2010 May 28
• 29 citations
  Random DNA fragmentation allows detection of single-copy, single-exon alterations of copy number by oligonucleotide array CGH in clinical FFPE samples
  Galen Hostetter, Su Young Kim, Stephanie Savage, Gerald C. Gooden, Michael T. Barrett, Jian Zhang, Lalitamba Alla, April Watanabe, Janine G. Einspahr, Anil Prasad, Bri...> ;Nucleic Acids Research. 2010 Jan 1
• 6 citations
  Sweet's syndrome with neurologic manifestations in a patient with esophageal adenocarcinoma: case report and review of the literature.
  Urszula A. Sobol, Karen L. Sherman, Jason W. Smith, Suneel Nagda, Kenneth C. Micetich, Brian J. Nickoloff, Margo Shoup> ;International Journal of Dermatology. 2009 Oct 1
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