BrianAlanSkaugMD

PubMed

• Fibroblast Subpopulations in Systemic Sclerosis: Functional Implications of Individual Subpopulations and Correlations with Clinical Features.
  Zhu, H., Luo, H., Tabib, T., Li, Y., Tao, Y., Matei, A., Lyons, M., Schett, G., Distler, J., Skaug, B., Lafyatis, R., Assassi, S.> ;The Journal of Investigative Dermatology. 2023 Dec 24
• CONQUER Scleroderma: association of gastrointestinal tract symptoms in early disease with resource utilization.
  Sarah Luebker, Tracy M Frech, Shervin Assassi, Brian Skaug, Jessica K Gordon, Kimberly Lakin, Elana J Bernstein, Yiming Luo, Virginia D Steen, Ami A Shah, Laura K Humm...> ;Rheumatology. 2023 Oct 3
• 1 citations
  Reduced digestion of circulating genomic DNA in systemic sclerosis patients with the DNASE1L3 R206C variant.
  Brian Skaug, Xinjian Guo, Yuanteng Jeff Li, Julio Charles, Kay T Pham, Jacob Couturier, Dorothy E Lewis, Claudia Bracaglia, Ivan Caiello, Maureen D Mayes, Shervin Assassi> ;Rheumatology. 2023 Sep 1
• Extensive and Persistent Extravascular Dermal Fibrin Deposition Characterizes Systemic Sclerosis.
  Jeffrey L Browning, Jag Bhawan, Anna Tseng, Nicholas Crossland, Andreea M Bujor, Katerina Akassoglou, Shervin Assassi, Brian Skaug, Jonathan Ho> ;Biorxiv. 2023 Jan 19
• 4 citations
  Reduced SPAG17 Expression in Systemic Sclerosis Triggers Myofibroblast Transition and Drives Fibrosis.
  Paulene Sapao, Elisha D O Roberson, Bo Shi, Shervin Assassi, Brian Skaug, Fred Lee, Alexandra Naba, Bethany E Perez White, Carlos Córdova-Fletes, Pei-Suen Tsou, Amr H ...> ;The Journal of Investigative Dermatology. 2023 Feb 1
• 5 citations
  False positive anti-Topoisomerase I (Scl-70) antibody results in clinical practice: A case series from a scleroderma referral center.
  Brian H Lam, Shervin Assassi, Julio Charles, Marka A Lyons, Bochra Jandali, Maureen D Mayes, Brian Skaug, Taherian, R.> ;Seminars in Arthritis and Rheumatism. 2022 Oct 1
• 1 citations
  Computed Tomography of the Chest to Screen for Interstitial Lung Disease in Patients With Systemic Sclerosis at Expert Scleroderma Centers in the United States.
  Elana J Bernstein, Shervin Assassi, Flavia V Castelino, Lorinda Chung, Chase Correia, Luke B Evnin, Tracy M Frech, Jessica K Gordon, Brian A Skaug, Faye N Hant, Laura ...> ;ACR Open Rheumatology. 2022 Jul 1
• 11 citations
  Large-scale analysis of longitudinal skin gene expression in systemic sclerosis reveals relationships of immune cell and fibroblast activity with skin thickness and a ...
  Brian Skaug, Marka A Lyons, William R Swindell, Gloria A Salazar, Minghua Wu, Tuan M Tran, Julio Charles, Connor P Vershel, Maureen D Mayes, Shervin Assassi> ;Annals of the Rheumatic Diseases. 2022 Apr 1
• 51 citations
  Type I interferon dysregulation in Systemic Sclerosis
  Brian Skaug, Shervin Assassi> ;Cytokine. 2020 Aug 1
• 88 citations
  Global skin gene expression analysis of early diffuse cutaneous systemic sclerosis shows a prominent innate and adaptive inflammatory profile
  Brian Skaug, Dinesh Khanna, William R. Swindell, Monique Hinchcliff, Tracy M. Frech, Virginia D. Steen, Faye N. Hant, Jessica K. Gordon, Ami A. Shah, Lisha Zhu, W. Jim...> ;Annals of the Rheumatic Diseases. 2020 Mar 1
• 49 citations
  Interferon regulatory factor 7 (IRF7) represents a link between inflammation and fibrosis in the pathogenesis of systemic sclerosis.
  Minghua Wu, Brian Skaug, Xiongjie Bi, Tingting Mills, Gloria Salazar, Xiaodong Zhou, John D. Reveille, Sandeep K. Agarwal, Michael R. Blackburn, Maureen D. Mayes, Sher...> ;Annals of the Rheumatic Diseases. 2019 Aug 22
• 9 citations
  Biomarkers in systemic sclerosis.
  Brian Skaug, Shervin Assassi> ;Current Opinion in Rheumatology. 2019 Nov 1
• 13 citations
  Antinuclear antibodies in the general population: positive association with inflammatory and vascular biomarkers but not traditional cardiovascular risk factors
  Elizabeth Blair Solow, Wanpen Vongpatanasin, Brian Skaug, David R. Karp, Colby Ayers, James A. de Lemos> ;Clinical and Experimental Rheumatology. 2018 Sep 17
• 9 citations
  Foxo3 Promotes Apoptosis of B Cell Receptor-Stimulated Immature B Cells, Thus Limiting the Window for Receptor Editing.
  Kristina Ottens, Rochelle M. Hinman, Evan Barrios, Brian Skaug, Laurie S. Davis, Quan Zhen Li, Diego H. Castrillon, Anne B. Satterthwaite> ;Journal of Immunology. 2018 Aug 1
• 7 citations
  Oesophageal rupture masquerading as STEMI.
  Brian Skaug, Kenneth R. Taylor, Somya A Chandrasekaran> ;BMJ Case Reports. 2016 Apr 11
• 19 citations
  Genetic Interaction between Lyn, Ets1, and Btk in the Control of Antibody Levels
  Jessica M. Mayeux, Brian Skaug, Wei Luo, Lisa Russell, Shinu John, Prontip Saelee, Hansaa Abbasi, Quan Zhen Li, Lee Ann Garrett-Sinha, Anne B. Satterthwaite> ;Journal of Immunology. 2015 Sep 1
• 21 citations
  Antinuclear Antibodies Are Associated With All-Cause Mortality and Cardiovascular Outcomes in the General Population
  Elizabeth Blair Solow, Wanpen Vongpatanasin, Brian Skaug, David R. Karp, Colby Ayers, James A. de Lemos> ;Journal of the American College of Cardiology. 2015 Jun 23
• 7 citations
  Multiple Isoforms of CDC25 Oppose ATM Activity to Maintain Cell Proliferation during Vertebrate Development
  Daniel Verduzco, Jennifer Shepard Dovey, Abhay A. Shukla, Elisabeth Kodym, Brian Skaug, James F. Amatruda> ;Molecular Cancer Research. 2012 Nov 1
• 193 citations
  Direct, Noncatalytic Mechanism of IKK Inhibition by A20
  Brian Skaug, Jueqi Chen, Fenghe Du, Jin He, Averil Ma, Zhijian J. Chen> ;Molecular Cell. 2011 Nov 18
• 875 citations
  MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response.
  Fajian Hou, Lijun Sun, Hui Zheng, Brian Skaug, Qiu-Xing Jiang, Zhijian J. Chen> ;Cell. 2011 Aug 5
• 120 citations
  Blood vessel tubulogenesis requires Rasip1 regulation of GTPase signaling
  Ke Xu, Anastasia Sacharidou, Stephen Fu, Diana C. Chong, Brian Skaug, Zhijian J. Chen, George E. Davis, Ondine Cleaver> ;Developmental Cell. 2011 Apr 19
• 169 citations
  Emerging Role of ISG15 in Antiviral Immunity
  Brian Skaug, Zhijian J. Chen> ;Cell. 2010 Oct 15
• 4 citations
  SUMO, Ubiquitin, UBL Proteins: Implications For Human Diseases - Fifth International Conference.
  Brian Skaug, Zhijian J. Chen> ;Idrugs. 2010 Apr 1
• 202 citations
  A Ubiquitin Replacement Strategy in Human Cells Reveals Distinct Mechanisms of IKK Activation by TNFα and IL-1β
  Ming Xu, Brian Skaug, Wenwen Zeng, Zhijian J. Chen> ;Molecular Cell. 2009 Oct 23
• 406 citations
  The role of ubiquitin in NF-kappaB regulatory pathways.
  Brian Skaug, Xiaomo Jiang, Zhijian J. Chen> ;Annual Review of Biochemistry. 2009 Jun 2
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Journal Articles

• Foxo3 Promotes Apoptosis of B Cell Receptor–Stimulated Immature B Cells, Thus Limiting the Window for Receptor Editing  
  Brian Skaug, Evan Barrios, Diego H Castrillon, The Journal of Immunology