
Bruce Colston Trapnell MD
Critical Care Medicine
Professor, Pediatrics, University of Cincinnati College of Medicine
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222 Piedmont AveSte 6000Cincinnati, OH 45219
Phone+1 513-475-7521
Fax+1 513-475-7327
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Education & Training
- Clinical Center at the National Institutes of HealthFellowship, Pulmonary Disease and Critical Care Medicine, 1988 - 1989
- Clinical Center at the National Institutes of HealthFellowship, Pulmonary Disease and Critical Care Medicine, 1987 - 1988
- Ohio State University HospitalResidency, Internal Medicine, 1984 - 1987
- University of Maryland School of MedicineClass of 1984
Certifications & Licensure
- OH State Medical License 1998 - 2025
- LA State Medical License 2021 - 2022
- DC State Medical License 1992 - 1998
- MD State Medical License 1987 - 1991
- American Board of Internal Medicine Internal Medicine
Clinical Trials
- Efficacy and Safety of Sirolimus in LAM Start of enrollment: 2006 Dec 01
- Study Evaluating Fosfomycin/Tobramycin for Inhalation in Cystic Fibrosis Patients With Pseudomonas Aeruginosa Lung Infection Start of enrollment: 2008 Nov 01
- Safety & Efficacy Study of rAAV1-CB-hAAT for Alpha-1 Antitrypsin Deficiency Start of enrollment: 2010 Jun 01
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Publications & Presentations
PubMed
- Pharmacokinetics and pharmacodynamics of inhaled molgramostim in healthy people.Bruce C Trapnell, Brenna C Carey, Brian R Robinson
BMJ Open Respiratory Research. 2025-09-18 - Phase 3 Trial of Inhaled Molgramostim in Autoimmune Pulmonary Alveolar Proteinosis.Bruce C Trapnell, Yoshikazu Inoue, Francesco Bonella, Tisha Wang, Cormac McCarthy
The New England Journal of Medicine. 2025-08-21 - Circulating and Magnetic Resonance Imaging Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease.Jonathan R Dillman, Jean A Tkach, Joel G Fletcher, David H Bruining, Aiming Lu
Inflammatory Bowel Diseases. 2025-05-12
Journal Articles
- Inhaled Molgramostim Therapy in Autoimmune Pulmonary Alveolar ProteinosisBruce Trapnell, MD, New England Journal of Medicine
Press Mentions
- HMN 2025: How Molgramostim Is Beneficial in Autoimmune Pulmonary Alveolar ProteinosisAugust 24th, 2025
- Inhaled Molgramostim Promising for Autoimmune Pulmonary Alveolar Proteinosis: Phase 3 Trial ShowsAugust 22nd, 2025
- Savara Announces New Data from Pivotal Phase 3 IMPALA-2 Trial of Molgramostim Nebulizer Solution (Molgramostim) in Patients with Autoimmune Pulmonary Alveolar Proteinosis (aPAP) Were Presented at the European Respiratory Society (ERS) Congress 2024September 8th, 2024
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Grant Support
- Technology to understand genetic variant effects in contextUNIVERSITY OF WASHINGTON2019–2029
- Versatile, exponentially scalable methods for single cell molecular profilingUNIVERSITY OF WASHINGTON2019–2028
- New software tools for differential analysis of single-cell genomics perturbation experimentsUNIVERSITY OF WASHINGTON2023–2027
- Human gene transfer & macrophage cell transplantation therapy of hereditary PAP (hPAP)CINCINNATI CHILDRENS HOSP MED CTR2021–2026
- Human gene transfer & macrophage cell transplantation therapy of hereditary PAP (hPAP)CINCINNATI CHILDRENS HOSP MED CTR2021–2026
- Retrospective Autoimmune PAP Natural History and Patient-Reported Outcomes StudyCINCINNATI CHILDRENS HOSP MED CTR2022–2025
- Pathogenesis-Based Diagnostics and Pharmacotherapeutics for PAPCINCINNATI CHILDRENS HOSP MED CTR2007–2025
- Interdisciplinary Training in Genome SciencesUNIVERSITY OF WASHINGTON1995–2025
- Pulmonary Development and Disease Pathogenesis Training ProgramCINCINNATI CHILDRENS HOSP MED CTR1994–2025
- Macrophage-Based Human Gene Therapy For Hereditary PAPNational Heart, Lung, And Blood Institute2011–2012
- Quantitative Chest Computed Tomography In Alpha-1-Antitrypsin DeficiencyNational Center For Research Resources2008
- Anticytokine Autoantibodies/Growth Factors In RARE Lung DiseasesNational Center For Research Resources2005–2008
- RARE Lung Disease Clinical Research NetworkNational Center For Research Resources2003–2008
- AAT Deficiency &Liver Diseases Caused By ProteinsNational Institute Of Diabetes And Digestive And Kidney Diseases2006
- Fourth Annual International Pulmonary Alveolar Proteinosis Research ConferenceNational Heart, Lung, And Blood Institute2006
- Regulation Of Alveolar Macrophage PhagocytosisNational Heart, Lung, And Blood Institute2003–2006
- Pulmonary Alveolar Proteinosis Research ConferenceNational Heart, Lung, And Blood Institute2005
- Conference--Pulmonary Alveolar Proteinosis ResearchNational Heart, Lung, And Blood Institute2004
- GM-CSF &Alveolar Macrophage Antiviral Lung DefenseNational Heart, Lung, And Blood Institute2001–2004
- Core--Viral VectorsNational Heart, Lung, And Blood Institute1997
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