
Bruce Colston Trapnell MD
Critical Care Medicine
Professor, Pediatrics, University of Cincinnati College of Medicine
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222 Piedmont AveSte 6000Cincinnati, OH 45219
Phone+1 513-475-7521
Fax+1 513-475-7327
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Education & Training
Clinical Center at the National Institutes of HealthFellowship, Pulmonary Disease and Critical Care Medicine, 1988 - 1989
Clinical Center at the National Institutes of HealthFellowship, Pulmonary Disease and Critical Care Medicine, 1987 - 1988
Ohio State University HospitalResidency, Internal Medicine, 1984 - 1987
University of Maryland School of MedicineClass of 1984
Certifications & Licensure
OH State Medical License 1998 - 2027
LA State Medical License 2021 - 2022
DC State Medical License 1992 - 1998
MD State Medical License 1987 - 1991
American Board of Internal Medicine Internal Medicine
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification EpicCare Inpatient 2014 Certified EHR Suite, Epic Systems Corporation, 2015-2017
- CMS Meaningful Use Stage 2 Certification EpicCare Inpatient 2014 Certified EHR Suite, Epic Systems Corporation, 2015-2017
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2015-2017
Clinical Trials
- Efficacy and Safety of Sirolimus in LAM Start of enrollment: 2006 Dec 01
- Study Evaluating Fosfomycin/Tobramycin for Inhalation in Cystic Fibrosis Patients With Pseudomonas Aeruginosa Lung Infection Start of enrollment: 2008 Nov 01
- Safety & Efficacy Study of rAAV1-CB-hAAT for Alpha-1 Antitrypsin Deficiency Start of enrollment: 2010 Jun 01
Publications & Presentations
PubMed
- The burden of autoimmune pulmonary alveolar proteinosis: a systematic review.Cormac McCarthy, Francesco Bonella, Tisha Wang, Yoshikazu Inoue, Brian Robinson
European Respiratory Review. 2026-04-01 - Pharmacokinetics and pharmacodynamics of inhaled molgramostim in healthy people.Bruce C Trapnell, Brenna C Carey, Brian R Robinson
BMJ Open Respiratory Research. 2025-09-18 - 3 citationsPhase 3 Trial of Inhaled Molgramostim in Autoimmune Pulmonary Alveolar Proteinosis.Bruce C Trapnell, Yoshikazu Inoue, Francesco Bonella, Tisha Wang, Cormac McCarthy
The New England Journal of Medicine. 2025-08-21
Journal Articles
- Inhaled Molgramostim Therapy in Autoimmune Pulmonary Alveolar ProteinosisBruce Trapnell, MD, New England Journal of Medicine
Press Mentions
HMN 2025: How Molgramostim Is Beneficial in Autoimmune Pulmonary Alveolar ProteinosisAugust 24th, 2025
Inhaled Molgramostim Promising for Autoimmune Pulmonary Alveolar Proteinosis: Phase 3 Trial ShowsAugust 22nd, 2025
Savara Announces New Data from Pivotal Phase 3 IMPALA-2 Trial of Molgramostim Nebulizer Solution (Molgramostim) in Patients with Autoimmune Pulmonary Alveolar Proteinosis (aPAP) Were Presented at the European Respiratory Society (ERS) Congress 2024September 8th, 2024
Grant Support
- Interdisciplinary Training in Genome SciencesUNIVERSITY OF WASHINGTON1995–2030
- Technology to understand genetic variant effects in contextUNIVERSITY OF WASHINGTON2019–2029
- Versatile, exponentially scalable methods for single cell molecular profilingUNIVERSITY OF WASHINGTON2019–2028
- New software tools for differential analysis of single-cell genomics perturbation experimentsUNIVERSITY OF WASHINGTON2023–2027
- Human gene transfer & macrophage cell transplantation therapy of hereditary PAP (hPAP)CINCINNATI CHILDRENS HOSP MED CTR2021–2026
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