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Office
Knopp Biosciences-Rockville
North Bethesda, MD 20852Phone+1 412-488-1776- Is this information wrong?
Education & Training
- National Institutes of Health Clinical CenterFellowship, Allergy and Immunology, 1988 - 1994
- University of Southern California/LAC+USC Medical CenterResidency, Internal Medicine, 1984 - 1987
- Keck School of Medicine of the University of Southern CaliforniaClass of 1984
Certifications & Licensure
- MD State Medical License 1991 - 2025
- CA State Medical License 1985 - 2024
- MA State Medical License 2003 - 2003
- American Board of Internal Medicine Internal Medicine
Clinical Trials
- Omalizumab to Treat Eosinophilic Gastroenteritis Start of enrollment: 2004 Jun 02
- Immunopathogenesis of Food Allergy and Eosinophilic Gastrointestinal Disorders Start of enrollment: 2010 Aug 30
- Sirolimus for Eosinophil-Associated Gastrointestinal Disorders Start of enrollment: 2013 Mar 07
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Publications & Presentations
PubMed
- 1 citationsSafety and Efficacy of Dexpramipexole in Eosinophilic Asthma (EXHALE): A randomized controlled trial.Salman Siddiqui, Sally E Wenzel, Michael E Bozik, Donald G Archibald, Steven I Dworetzky, James L Mather, Randall Killingsworth, Natasha Ghearing, Justin T Schwartz, S...> ;The Journal of Allergy and Clinical Immunology. 2023 Nov 1
- 6 citationsUrine eosinophil-derived neurotoxin: A potential marker of activity in select eosinophilic disorders.Michelle A Makiya, Paneez Khoury, Fei Li Kuang, Alexis Dominique Mata, Sana Mahmood, Abbie Bowman, David Espinoza, Nicholas Kovacs, Thomas Brown, Nicole Holland, Laure...> ;Allergy. 2023 Jan 1
- 59 citationsDexpramipexole depletes blood and tissue eosinophils in nasal polyps with no change in polyp size.Tanya M. Laidlaw, Calman Prussin, Reynold A. Panettieri, Stella E. Lee, Berrylin J. Ferguson, Nithin D. Adappa, Andrew P. Lane, Marina L. Palumbo, Mary C. Sullivan, Do...> ;The Laryngoscope. 2019 Feb 1
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Journal Articles
- Safety and Efficacy of Dexpramipexole in Eosinophilic Asthma (EXHALE): A randomized controlled trialSalman Siddiqui, BM, FRCP, PhD,a Sally E. Wenzel, MD,b Michael E. Bozik, MD,c Donald G. Archibald, MPhil,c Steven I. Dworetzky, PhD,c James L. Mather, BS,c Randall Kil..., Journal of Allergy and Clinical Immunology, 11/2023
Press Mentions
- Knopp Biosciences Presents New Phase 2 Data at AAAAI 2022 Demonstrating That Oral Dexpramipexole Improves Airflow Obstruction as Measured by Forced Expiry Volume (FEV1), Largely Through Its Effect on Forced Vital Capacity (FVC)February 28th, 2022
- Knopp Biosciences Reports Positive Results from the Phase 2 EXHALE Trial of Oral Dexpramipexole in Moderate-to-Severe Eosinophilic Asthma at ATS 2021May 17th, 2021
- Knopp Biosciences to Present Clinical Data for Dexpramipexole at 11th Biennial Symposium of the International Eosinophil SocietyJuly 9th, 2019
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Grant Support
- Highly Differentiated Il5+ TH2 Cells In Food Allergy And Eosinophilic GI DiseaseNational Institute Of Allergy And Infectious Diseases2010–2011
- Functional And Epigenetic Analysis Of TH2 HeterogeneityNational Institute Of Allergy And Infectious Diseases2010–2011
- T Cell Pathogenesis Of Food AllergyNational Institute Of Allergy And Infectious Diseases2009
- Developmental Immunotherapeutics Of Allergic DiseasesNational Institute Of Allergy And Infectious Diseases2009
- Memory T Cell Responses To Food AllergyNational Institute Of Allergy And Infectious Diseases2008
- Developmental Immunotherapeutics Of Allergic DiseasesNational Institute Of Allergy And Infectious Diseases2008
- Induction And Inhibition Of Ige-Mediated Hypersensitivity To VaccinesNational Institute Of Allergy And Infectious Diseases2007
- Developmental Immunotherapeutics For Allergic Diseases And AsthmaNational Institute Of Allergy And Infectious Diseases2007
- Developmental Immunotherapeutics For Allergic Diseases ANational Institute Of Allergy And Infectious Diseases2002–2006
- Cytokine Profiles In Asthma And Allergic DiseasesNational Institute Of Allergy And Infectious Diseases2002–2006
- Developmental Immunotherapeutics-Allergic Disease/AsthmaNational Institute Of Allergy And Infectious Diseases2005
- Immunotherapeutics For Allergic Diseases And AsthmaNational Institute Of Allergy And Infectious Diseases2003
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