CarlHSadowskyMD

Neurology • West Palm Beach, FL

Clinical Professor of Neurology, Nova SE University Fort Lauderdale, Fl

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Office
4631 N Congress Ave
200
West Palm Beach, FL 33407
Phone+1 561-845-0500

Fax+1 561-296-1101
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Education & Training

Dartmouth-Hitchcock/Mary Hitchcock Memorial HospitalResidency, Neurology, 1973 - 1976
Dartmouth-Hitchcock/Mary Hitchcock Memorial HospitalResidency, Internal Medicine, 1971 - 1973
Weill Cornell MedicineClass of 1971

Certifications & Licensure

FL State Medical License 1979 - 2025
American Board of Psychiatry and Neurology Neurology

Awards, Honors, & Recognition

Gulfstream FL-Palm Beach Castle Connolly, 2006-2014
America's Top Doctors Castle Connolly, 2002-2014
CMS Meaningful Use Stage 1 Certification eClinicalWorks EHR, eClinicalWorks LLC, 2011-2013
SouthFloridaCEO: Top Doctors Castle Connolly, 2002-2003
Miami Metro City Guide: Top Doctors Castle Connolly, 2001
Top Doctors: Florida Castle Connolly, 2000
Top MD Consumers Checkbook
Super Doctor SuperDoctors.com
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Clinical Trials

Evaluation of a Handheld Event Related Potential (ERP)/Quantitative Electroencephalography (qEEG) System (COGNISION™) as a Useful Cognitive Biomarker for Alzheimer's Disease. Start of enrollment: 2010 Dec 01
Completed
AC-1204 26-Week Long Term Efficacy Response Trial With Optional Open-label Ext Start of enrollment: 2013 Mar 01
Completed
Phase 2, Phase 3
Effect of NeuroAD on the Cognitive Function of Alzheimer Patients Start of enrollment: 2013 Oct 01
Completed
Not Applicable
Clinical Trial of Solanezumab for Older Individuals Who May be at Risk for Memory Loss Start of enrollment: 2014 Feb 28
Completed
Phase 3
Analysis of 18F-AV-1451 PET Imaging in Cognitively Healthy, MCI, and AD Subjects Start of enrollment: 2013 Dec 01
Completed
Phase 2, Phase 3
Simufilam 100 mg for Mild-to-Moderate Alzheimer's Disease Start of enrollment: 2021 Nov 03
Active, not recruiting
Phase 3
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Publications & Presentations

PubMed

29 citations
Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration
Nicolai Franzmeier, M. Suárez-Calvet, Lukas Frontzkowski, Annah M. Moore, Timothy J. Hohman, Estrella Morenas-Rodríguez, Brigitte Nuscher, Leslie M. Shaw, John Q. Troj...> ;Molecular Neurodegeneration. 2020 Oct 8
69 citations
Effects of a combined transcranial magnetic stimulation (TMS) and cognitive training intervention in patients with Alzheimer's disease
Marwan N. Sabbagh, Carl H. Sadowsky, Babak Tousi, Marc E. Agronin, Gustavo Alva, Carmel Armon, Charles Bernick, Andrew P. Keegan, Stella Karantzoulis, Eyal Baror, Mora...> ;Alzheimer's & Dementia. 2020 Apr 1
41 citations
Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states
Ines Mahjoub, Mohamed Ali Mahjoub, Islem Rekik, Michael W. Weiner, Paul S. Aisen, Ronald C. Petersen, Cliford Jack, William J. Jagust, John Q. Trojanowki, Arthur W. To...> ;Scientific Reports. 2018 Mar 7
34 citations
Use of Flutemetamol F 18-Labeled Positron Emission Tomography and Other Biomarkers to Assess Risk of Clinical Progression in Patients With Amnestic Mild Cognitive Impa...
David A. Wolk, Carl H. Sadowsky, Beth Safirstein, Juha O. Rinne, Ranjan Duara, Richard Perry, Marc Agronin, Jose Gamez, Jiong Shi, Adrian Ivanoiu, Lennart Minthon, Zuz...> ;JAMA Neurology. 2018 Sep 1
6 citations
Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty
Lei Du, Kefei Liu, Xiaohui Yao, Jingwen Yan, Shannon L. Risacher, Junwei Han, Lei Guo, Andrew J. Saykin, Li Shen, Michael W. Weiner, Paul S. Aisen, Ronald C. Petersen,...> ;Scientific Reports. 2017 Dec 1
10 citations
Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features.
Asha Singanamalli, Haibo Wang, Anant Madabhushi, Michael W. Weiner, Paul S. Aisen, Ronald C. Petersen, Clifford R. Jack, William J. Jagust, John Q. Trojanowki, Arthur ...> ;Scientific Reports. 2017 Dec 1
36 citations
Long-Term Extensions of Randomized Vaccination Trials of ACC-001 and QS-21 in Mild to Moderate Alzheimer's Disease.
Michael Hüll, Carl H. Sadowsky, Heii Arai, Ghislaine Le Prince Leterme, Ann R Holstein, Kevin Booth, Yahong Peng, Tamotsu Yoshiyama, Hideo Suzuki, Nzeera Ketter, Enchi...> ;Current Alzheimer Research. 2017 Jun 30
32 citations
Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease.
Meiyan Huang, Wei Yang, Qianjin Feng, Wufan Chen, Michael W. Weiner, Paul S. Aisen, Ronald C. Petersen, Clifford R. Jack, William J. Jagust, John Q. Trojanowki, Arthur...> ;Scientific Reports. 2017 Jan 12
60 citations
Performance of [18F]flutemetamol amyloid imaging against the neuritic plaque component of CERAD and the current (2012) NIA-AA recommendations for the neuropathologic d...
Stephen Salloway, Jose Gamez, Upinder Singh, Carl H. Sadowsky, Teresa Villena, Marwan N. Sabbagh, Thomas G. Beach, Ranjan Duara, Adam S. Fleisher, Kirk A. Frey, Zuzana...> ;Alzheimer's & Dementia. 2017 Jan 1
30 citations
Effectiveness of Florbetapir PET Imaging in Changing Patient Management.
Michael Pontecorvo, Andrew Siderowf, Bruno Dubois, P. Murali Doraiswamy, Giovanni B. Frisoni, Michael Grundman, Flavio Nobili, Carl H. Sadowsky, Stephen Salloway, Anup...> ;Dementia and Geriatric Cognitive Disorders. 2017 Aug 5
203 citations
Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer's pathology.
Taylor W. Schmitz, R. Nathan Spreng, Michael W. Weiner, Paul S. Aisen, Ronald C. Petersen, Clifford R. Jack, William J. Jagust, John Q. Trojanowki, Arthur W. Toga, Lau...> ;Nature Communications. 2016 Nov 4
39 citations
A clinical trial to validate event-related potential markers of Alzheimer's disease in outpatient settings
Marco Cecchi, Dennis Moore, Carl H. Sadowsky, Paul R. Solomon, P. Murali Doraiswamy, Charles D. Smith, Gregory A. Jicha, Andrew E. Budson, Steven E. Arnold, Kalford C....> ;Alzheimer's & Dementia. 2015 Dec 1
11 citations
The impact of PICALM genetic variations on reserve capacity of posterior cingulate in AD continuum.
Wei Xu, Hui-Fu Wang, Lin Tan, Meng-Shan Tan, Chen-Chen Tan, Xi-Chen Zhu, Dan Miao, Wan-Jiang Yu, Teng Jiang, Lan Tan, Jin-Tai Yu, Michael W. Weiner, Paul S. Aisen, Ron...> ;Scientific Reports. 2016 Apr 27
14 citations
Vanutide Cridificar (ACC-001) and QS-21 Adjuvant in Individuals with Early Alzheimer's Disease: Amyloid Imaging Positron Emission Tomography and Safety Results from a ...
C H van Dyck, Carl H. Sadowsky, G Le Prince Leterme, Kevin Booth, Yahong Peng, Kenneth Marek, Nzeera Ketter, Enchi Liu, B T Wyman, Nicholas Jackson, M Slomkowski, J M ...> ;The Journal of Prevention of Alzheimer's Disease. 2016 Jan 1
63 citations
Two Phase 2 Multiple Ascending-Dose Studies of Vanutide Cridificar (ACC-001) and QS-21 Adjuvant in Mild-to-Moderate Alzheimer's Disease.
Florence Pasquier, Carl H. Sadowsky, Ann R Holstein, Ghislaine Le Prince Leterme, Yahong Peng, Nicholas Jackson, Nick C. Fox, Nzeera Ketter, Enchi Liu, J. Michael Ryan> ;Journal of Alzheimer's Disease. 2016 Jan 1
33 citations
Detection of Amyloid β Signature in the Lens and Its Correlation in the Brain to Aid in the Diagnosis of Alzheimer's Disease.
Charles Kerbage, Carl H. Sadowsky, Pierre N. Tariot, Marc Agronin, Gustavo Alva, F. Darell Turner, Nilan Dennis J, Anne Cameron, Gerald D. Cagle, Paul D. Hartung> ;American Journal of Alzheimer's Disease and Other Dementias. 2015 Dec 1
17 citations
Adaptive, dose-finding phase 2 trial evaluating the safety and efficacy of ABT-089 in mild to moderate Alzheimer disease.
Robert A. Lenz, Yili Pritchett, Scott M. Berry, Daniel A. Llano, Shu Han, Donald A. Berry, Carl H. Sadowsky, Walid M. Abi-Saab, Mario D. Saltarelli> ;Alzheimer Disease and Associated Disorders. 2015 Sep 7
7 citations
Evaluating Response to High‐Dose 13.3 mg/24 h Rivastigmine Patch in Patients with Severe Alzheimer's Disease
Martin R. Farlow, Carl H. Sadowsky, Drew M. Velting, Xiangyi Meng, M. Zahur Islam> ;CNS Neuroscience & Therapeutics. 2015 Jun 1
200 citations
Phase 3 Trial of Flutemetamol Labeled With Radioactive Fluorine 18 Imaging and Neuritic Plaque Density
Craig Curtis, Jose Gamez, Upinder Singh, Carl H. Sadowsky, Teresa Villena, Marwan N. Sabbagh, Thomas G. Beach, Ranjan Duara, Adam S. Fleisher, Kirk A. Frey, Zuzana Wal...> ;JAMA Neurology. 2015 Mar 1
9 citations
A 24-Week, Open-Label Extension Study to Investigate the Long-term Safety, Tolerability, and Efficacy of 13.3 mg/24 h Rivastigmine Patch in Patients With Severe Alzhei...
Martin R. Farlow, George T. Grossberg, Carl H. Sadowsky, Xiangyi Meng, Drew M. Velting> ;Alzheimer Disease and Associated Disorders. 2014 Nov 1
18 citations
Rivastigmine from capsules to patch: therapeutic advances in the management of Alzheimer's disease and Parkinson's disease dementia.
Carl H. Sadowsky, Joseph L. Micca, George T. Grossberg, Drew M. Velting> ;The Primary Care Companion for CNS Disorders. 2014 Sep 4
9 citations
Efficacy of higher‐dose 13.3 mg/24 h (15 cm2) rivastigmine patch on the Alzheimer's Disease Assessment Scale–cognitive subscale: domain and individual item analysis
Gustavo Alva, Richard S. Isaacson, Carl H. Sadowsky, George T. Grossberg, Xiangyi Meng, Monique Somogyi> ;International Journal of Geriatric Psychiatry. 2014 Sep 1
145 citations
Florbetapir F 18 amyloid PET and 36-month cognitive decline:a prospective multicenter study
P. M. Doraiswamy, Reisa A. Sperling, K Johnson, Eric M. Reiman, Terence Z. Wong, M N Sabbagh, C H Sadowsky, Adam S. Fleisher, Alana Carpenter, Abhinay D. Joshi, Ming L...> ;Molecular Psychiatry. 2014 Mar 11
31 citations
Neuropathologic heterogeneity does not impair florbetapir-positron emission tomography postmortem correlates.
Brittany N. Dugger, Christopher M. Clark, Geidy E. Serrano, Monica Mariner, Barry J. Bedell, R. Edward Coleman, P. Murali Doraiswamy, Ming Lu, Adam S. Fleisher, Eric M...> ;Journal of Neuropathology and Experimental Neurology. 2014 Jan 1
70 citations
The S-Connect study: results from a randomized, controlled trial of Souvenaid in mild-to-moderate Alzheimer’s disease
Raj C. Shah, Patrick Joseph Gerardus Hendrikus Kamphuis, Sue Leurgans, S. H. N. Swinkels, Carl H. Sadowsky, Anke Bongers, Stephen A Rappaport, Joseph F. Quinn, R.L. Wi...> ;Alzheimer's Research & Therapy. 2013 Nov 26
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Press Mentions

Associations of Regional Brain Structural Differences with Aging, Modifiable Risk Factors for Dementia, and Cognitive PerformanceDecember 2nd, 2019
Association of Altered Liver Enzymes with AD, Cognition, Neuroimaging Measures, and Cerebrospinal Fluid BiomarkersJuly 31st, 2019