CarlosSubausteMD

PubMed

• Advanced Glycation End Products Upregulate CD40 in Human Retinal Endothelial and Müller Cells: Relevance to Diabetic Retinopathy.
  Jose-Andres C Portillo, Amelia Pfaff, Sarah Vos, Matthew Weng, Ram H Nagaraj, Carlos S Subauste> ;Cells. 2024 Feb 29
• Animal Models for Toxoplasma gondii Infection.
  Carlos S Subauste, Alyssa Hubal> ;Current Protocols. 2023 Sep 1
• 2 citations
  CD40 Upregulation in the Retina of Patients With Diabetic Retinopathy: Association With TRAF2/TRAF6 Upregulation and Inflammatory Molecule Expression.
  Sarah Vos, Rachel Aaron, Matthew Weng, Jad Daw, Emmanuel Rodriguez-Rivera, Carlos S Subauste> ;Investigative Ophthalmology & Visual Science. 2023 Jun 1
• 13 citations
  Disruption of retinal inflammation and the development of diabetic retinopathy in mice by a CD40-derived peptide or mutation of CD40 in Müller cells.
  Jose-Andres C Portillo, Jin-Sang Yu, Sarah Vos, Reena Bapputty, Yalitza Lopez Corcino, Alyssa Hubal, Jad Daw, Sahil Arora, Wenyu Sun, Zheng-Rong Lu, Carlos S Subauste> ;Diabetologia. 2022 Dec 1
• 3 citations
  CD40 Expressed in Endothelial Cells Promotes Upregulation of ICAM-1 But Not Pro-Inflammatory Cytokines, NOS2 and P2X7 in the Diabetic Retina.
  Jin‐Sang Yu, Jad H. Daw, Jose-Andres C. Portillo, Carlos S. Subauste> ;Investigative Ophthalmology & Visual Science. 2021 Sep 2
• 9 citations
  Recent Advances in the Roles of Autophagy and Autophagy Proteins in Host Cells During Toxoplasma gondii Infection and Potential Therapeutic Implications
  Carlos S. Subauste> ;Frontiers in Cell and Developmental Biology. 2021 Jun 9
• 6 citations
  A cell-penetrating CD40-TRAF2,3 blocking peptide diminishes inflammation and neuronal loss after ischemia/reperfusion.
  Jose-Andres C. Portillo, Jin‐Sang Yu, Samuel Hansen, Timothy S. Kern, M. Cecilia Subauste, Carlos S. Subauste> ;FASEB Journal. 2021 Mar 1
• 1551 citations
  Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
  Ko, F., Daniel J. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, Marie H. Abildgaard, Yakubu Prin...> ;Autophagy. 2021 Feb 8
• 25 citations
  The CD40-ATP-P2X 7 Receptor Pathway: Cell to Cell Cross-Talk to Promote Inflammation and Programmed Cell Death of Endothelial Cells.
  Carlos S. Subauste> ;Frontiers in Immunology. 2019 Dec 17
• 8 citations
  CD40 in Endothelial Cells Restricts Neural Tissue Invasion by Toxoplasma gondii.
  Jose-Andres C. Portillo, Jennifer Van Grol, Saad Saffo, Yalitza Lopez Corcino, Myriam E. Rodriguez, Barbara A. Fox, David J. Bzik, Nicole L. Ward, George R. Dubyak, Ro...> ;Infection and Immunity. 2019 Jul 23
• 20 citations
  Toxoplasma gondii induces prolonged host epidermal growth factor receptor signalling to prevent parasite elimination by autophagy: Perspectives for in vivo control of ...
  Yalitza Lopez Corcino, Shekina Gonzalez Ferrer, Luz Eliana Mantilla, Sophia Trikeriotis, Jin‐Sang Yu, Steven Kim, Samuel Hansen, Jose-Andres C. Portillo, Carlos S. Sub...> ;Cellular Microbiology. 2019 Oct 1
• 14 citations
  Interplay Between Toxoplasma gondii, Autophagy, and Autophagy Proteins.
  Carlos S. Subauste> ;Frontiers in Cellular and Infection Microbiology. 2019 May 1
• 16 citations
  Epidermal growth factor receptor promotes cerebral and retinal invasion by Toxoplasma gondii.
  Yalitza Lopez Corcino, Jose-Andres C. Portillo, Carlos S. Subauste> ;Scientific Reports. 2019 Jan 24
• 43 citations
  Toxoplasma gondii induces FAK-Src-STAT3 signaling during infection of host cells that prevents parasite targeting by autophagy.
  Jose-Andres C. Portillo, Luis Muniz-Feliciano, Yalitza Lopez Corcino, So Jung Lee, Jennifer Van Grol, Sarah J. Parsons, William P. Schiemman, Carlos S. Subauste> ;Plos Pathogens. 2017 Oct 16
• 8 citations
  Loss of CD40 attenuates experimental diabetes-induced retinal inflammation but does not protect mice from electroretinogram defects.
  Ivy S. Samuels, Jose-Andres C. Portillo, Yanling Miao, Timothy S. Kern, Carlos S. Subauste> ;Visual Neuroscience. 2017 Jan 1
• 3 citations
  CD40, a Novel Inducer of Purinergic Signaling: Implications to the Pathogenesis of Experimental Diabetic Retinopathy.
  Carlos S. Subauste> ;Vision. 2017 Aug 12
• 17 citations
  Ligation of CD40 in Human Müller Cells Induces P2X7 Receptor–Dependent Death of Retinal Endothelial Cells
  Jose Andres C Portillo, Yalitza Lopez Corcino, George R. Dubyak, Timothy S. Kern, Shigemi Matsuyama, Carlos S. Subauste> ;Investigative Ophthalmology & Visual Science. 2016 Nov 1
• 28 citations
  Identification of Signaling Pathways by Which CD40 Stimulates Autophagy and Antimicrobial Activity against Toxoplasma gondii in Macrophages.
  Elizabeth Liu, Yalitza Lopez Corcino, Jose-Andres C. Portillo, Yanling Miao, Carlos S. Subauste> ;Infection and Immunity. 2016 Sep 1
• 87 citations
  CD40 in Retinal Müller Cells Induces P2X7-Dependent Cytokine Expression in Macrophages/Microglia in Diabetic Mice and Development of Early Experimental Diabetic Retino...
  Jose Andres C Portillo, Yalitza Lopez Corcino, Yanling Miao, Jie Tang, Nader Sheibani, Timothy S. Kern, George R. Dubyak, Carlos S. Subauste> ;Diabetes. 2017 Feb 1
• 673 citations
  Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
  Vyas, J. M., Daniel J Klionsky, Kotb Abdelmohsen, Akihisa Abe, Md Joynal Abedin, Hagai Abeliovich, Abraham Acevedo Arozena, Hiroaki Adachi, Christopher M Adams, Peter ...> ;Autophagy. 2016 Jan 1
• 18 citations
  CD40-TRAF Signaling Upregulates CX3CL1 and TNF-α in Human Aortic Endothelial Cells but Not in Retinal Endothelial Cells.
  Jennifer A. Greene, Jose-Andres C. Portillo, Yalitza Lopez Corcino, Carlos S. Subauste> ;Plos One. 2015 Dec 28
• 28 citations
  Di-retinoid-pyridinium-ethanolamine (A2E) Accumulation and the Maintenance of the Visual Cycle Are Independent of Atg7-mediated Autophagy in the Retinal Pigmented Epit...
  Lindsay Perusek, Bhubanananda Sahu, Tanu Parmar, Hiroshi Maeno, Eisuke Arai, Yun-Zheng Le, Carlos S. Subauste, Yu Chen, Krzysztof Palczewski, Akiko Maeda> ;The Journal of Biological Chemistry. 2015 Nov 27
• 31 citations
  Atg5 but not Atg7 in dendritic cells enhances IL-2 and IFN-γ production by Toxoplasma gondii-reactive CD4+ T cells.
  Elizabeth Liu, Jennifer Van Grol, Carlos S. Subauste> ;Microbes and Infection. 2015 Apr 1
• 24 citations
  Blockade of CD40–TRAF2,3 or CD40–TRAF6 is sufficient to inhibit pro-inflammatory responses in non-haematopoietic cells
  Jose-Andres C. Portillo, Jennifer A. Greene, Isaac Schwartz, Maria Cecilia Subauste, Carlos S. Subauste> ;Immunology. 2015 Jan 1
• 21 citations
  Proinflammatory Responses Induced by CD40 in Retinal Endothelial and Müller Cells are Inhibited by Blocking CD40-Traf2,3 or CD40-Traf6 Signaling
  Jose Andres C Portillo, Isaac Schwartz, Simona Zarini, Reena Bapputty, Timothy S. Kern, Rose Gubitosi-Klug, Robert C. Murphy, M. Cecilia Subauste, Carlos S. Subauste> ;Investigative Ophthalmology & Visual Science. 2014 Dec 4
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Journal Articles

• Disruption of retinal inflammation and the development of diabetic retinopathy in mice by a CD40-derived peptide or mutation of CD40 in Müller cells  
  Jose-Andres C Portillo, Jin-Sang Yu, Sarah Vos, Reena Bapputty, Yalitza Lopez Corcino, Alyssa Hubal, Jad Daw, Sahil Arora, Wenyu Sun, Zheng-Rong Lu, Carlos S Subauste, Diabetologia, 8/3/2022