CarlyneCoolMD

PubMed

• 3 citations
  Spatially distinct molecular patterns of gene expression in idiopathic pulmonary fibrosis.
  Rachel Z Blumhagen, Jonathan S Kurche, Carlyne D Cool, Avram D Walts, David Heinz, Tasha E Fingerlin, Ivana V Yang, David A Schwartz> ;Respiratory Research. 2023 Nov 17
• Pathologic Findings in Severe Coal Workers' Pneumoconiosis in Contemporary US Coal Miners.
  Carlyne D Cool, Jill Murray, Naseema I Vorajee, Cecile S Rose, Lauren M Zell-Baran, Soma Sanyal, Angela D Franko, Kirsten S Almberg, Cayla Iwaniuk, Leonard H T Go, Fra...> ;Archives of Pathology & Laboratory Medicine. 2023 Oct 18
• 2 citations
  Clonal Somatic Mutations in Chronic Lung Diseases Are Associated with Reduced Lung Function.
  Jeong H Yun, M A Wasay Khan, Auyon Ghosh, Brian D Hobbs, Peter J Castaldi, Craig P Hersh, Peter G Miller, Carlyne D Cool, Frank Sciurba, Lucas Barwick, Andrew H Limper...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Dec 1
• Findings on High Resolution Computed Tomography in Symptomatic Veterans with Deployment-Related Lung Disease.
  Cecile S Rose, Lauren M Zell-Baran, Carlyne Cool, Camille M Moore, Jenna Wolff, Andrea S Oh, Tilman Koelsch, John C Richards, Silpa D Krefft, Carla G Wilson, David A L...> ;Journal of Thoracic Imaging. 2023 Sep 15
• Immunological and metabolic characterization of environmental Mycobacterium chimaera infection in a murine model.
  Stephanie N Dawrs, Ravleen Virdi, M Nurul Islam, Nabeeh A Hasan, Grant J Norton, James L Crooks, Jane Parr, David Heinz, Carlyne D Cool, John T Belisle, Edward D Chan,...> ;Microbes and Infection. 2023 Jul 14
• Historical shift in pathological type of progressive massive fibrosis among coal miners in the USA.
  Leonard H T Go, Cecile S Rose, Lauren M Zell-Baran, Kirsten S Almberg, Cayla Iwaniuk, Sidney Clingerman, Diana L Richardson, Jerrold L Abraham, Carlyne D Cool, Angela ...> ;Occupational and Environmental Medicine. 2023 Aug 1
• Characterizing Lung Particulates Using Quantitative Microscopy in Coal Miners With Severe Pneumoconiosis.
  Jeremy T Hua, Carlyne D Cool, Heather A Lowers, Leonard H T Go, Lauren M Zell-Baran, Emily A Sarver, Kirsten S Almberg, Kathy D Pang, Susan M Majka, Angela D Franko, N...> ;Archives of Pathology & Laboratory Medicine. 2024 Mar 1
• Lymphangioleiomyomatosis and Other Cystic Lung Diseases.
  Matthew Koslow, David A Lynch, Carlyne D Cool, Steve D Groshong, Gregory P Downey> ;Immunology and Allergy Clinics of North America. 2023 May 1
• 1 citations
  Pathology and Mineralogy of the Pneumoconioses.
  Jeremy T Hua, Carlyne D Cool, Francis H Y Green> ;Seminars in Respiratory and Critical Care Medicine. 2023 Jun 1
• Mining Tenure and Job Duties Differ Among Contemporary and Historic Underground Coal Miners With Progressive Massive Fibrosis.
  Lauren M Zell-Baran, Leonard H T Go, Emily Sarver, Kirsten S Almberg, Cayla Iwaniuk, Francis H Y Green, Jerrold L Abraham, Carlyne Cool, Angela Franko, Ann F Hubbs, Ji...> ;Journal of Occupational and Environmental Medicine. 2023 Apr 1
• 2 citations
  Dichotomous role of integrin-β5 in lung endothelial cells.
  Neil Blanchard, Patrick A Link, Daniela Farkas, Brennan Harmon, Jaylen Hudson, Srimathi Bogamuwa, Bryce Piper, Kayla Authelet, Carlyne D Cool, Rebecca L Heise, Robert ...> ;Pulmonary Circulation. 2022 Oct 1
• 2 citations
  Single-cell transcriptome mapping identifies a local, innate B cell population driving chronic rejection after lung transplantation.
  Natalia F Smirnova, Kent Riemondy, Marta Bueno, Susan Collins, Pavan Suresh, Xingan Wang, Kapil N Patel, Carlyne Cool, Melanie Königshoff, Nirmal S Sharma, Oliver Eick...> ;JCI Insight. 2022 Sep 22
• 11 citations
  Small airways and airspace inflammation and injury distinguish lung histopathology in deployed military personnel from healthy and diseased lungs.
  Cecile S Rose, Camille M Moore, Lauren M Zell-Baran, Silpa Krefft, Jenna Wolff, Kathy Pang, Jane Parr, Carlyne Cool> ;Human Pathology. 2022 Jun 1
• 3 citations
  Characterization of Immune Cells From the Lungs of Patients With Chronic Non-Tuberculous Mycobacteria orInfection.
  Alan R Schenkel, John D Mitchell, Carlyne D Cool, Xiyuan Bai, Steve Groshong, Tilman Koelsch, Deepshikha Verma, Diane Ordway, Edward D Chan> ;Immune Network. 2022 Jun 1
• 15 citations
  Pathology and Mineralogy Demonstrate Respirable Crystalline Silica Is a Major Cause of Severe Pneumoconiosis in U.S. Coal Miners.
  Robert A Cohen, Cecile S Rose, Leonard H T Go, Lauren M Zell-Baran, Kirsten S Almberg, Emily A Sarver, Heather A Lowers, Cayla Iwaniuk, Sidney M Clingerman, Diana L Ri...> ;Annals of the American Thoracic Society. 2022 Sep 1
• Use of a novel chinchilla skull base repair model to test a photo-initiated thiol-ene biopolymer.
  Adam M Terella, Peter Mariner, Carlyne D Cool, Vijay R Ramakrishnan> ;International Forum of Allergy & Rhinology. 2022 Oct 1
• 2 citations
  Histopathologic Analysis of Surgically Resected Lungs of Patients with Non-tuberculous Mycobacterial Lung Disease: a Retrospective and Hypothesis-generating Study.
  Sangbong Choi, Kyle J Potts, Meghan D Althoff, Guillermo Jimenez, Xiyuan Bai, Kara M Calhoun, Carlyne D Cool, Edward D Chan> ;The Yale Journal of Biology and Medicine. 2021 Dec 1
• 4 citations
  Histopathological Correlation of Acute on Chronic Eosinophilic Pneumonitis Caused by Vaporized Cannabis Oil Inhalation
  Michael H. Lee, Carlyne D. Cool, James P. Maloney> ;Chest. 2021 Mar 1
• 30 citations
  Rituximab and antimetabolite treatment of granulomatous and lymphocytic interstitial lung disease in common variable immunodeficiency.
  James W. Verbsky, Mary Hintermeyer, Pippa Simpson, Mingen Feng, Jody Barbeau, Nagarjun Rao, Carlyne D. Cool, L.A. Sosa-Lozano, Dhiraj Baruah, Erin Hammelev, Alyssa Bus...> ;The Journal of Allergy and Clinical Immunology. 2021 Feb 1
• 1 citations
  Pathological entities that may affect the lungs and the myocardium. Evaluation with chest CT and cardiac MR.
  Felipe Sanchez, Jose M. Gutierrez, Lan-Chau Kha, Laura Jimenez-Juan, Carlyne D. Cool, Daniel Vargas, Anastasia Oikonomou> ;Clinical Imaging. 2021 Feb 1
• 49 citations
  Chronic Hypersensitivity Pneumonitis, an Interstitial Lung Disease with Distinct Molecular Signatures.
  Haruhiko Furusawa, Jonathan Cardwell, Tsukasa Okamoto, Avram D Walts, Iain R. Konigsberg, Jonathan S. Kurche, Tami J. Bang, Marvin I. Schwarz, Kevin K. Brown, Jonathan...> ;American Journal of Respiratory and Critical Care Medicine. 2020 Nov 13
• 31 citations
  IgA Antibodies Directed Against Citrullinated Protein Antigens Are Elevated in Patients With Idiopathic Pulmonary Fibrosis.
  Joshua J. Solomon, Scott Matson, Lindsay B. Kelmenson, Jonathan H. Chung, Stephen B. Hobbs, Ivan O. Rosas, Paul F. Dellaripa, Tracy J. Doyle, Sergio Poli, Anthony J. E...> ;Chest. 2020 Jun 1
• 34 citations
  The hallmarks of severe pulmonary arterial hypertension: the cancer hypothesis—ten years later
  Carlyne D. Cool, Wolfgang M. Kuebler, Harm Jan Bogaard, Edda Spiekerkoetter, Mark R. Nicolls, Norbert F. Voelkel> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2020 Feb 5
• 15 citations
  Clonally selected primitive endothelial cells promote occlusive pulmonary arteriopathy and severe pulmonary hypertension in rats exposed to chronic hypoxia.
  A.R. Bhagwani, Daniela Farkas, Brennan Harmon, Kayla J. Authelet, Carlyne D. Cool, Martin Kolb, Elena A. Goncharova, Mervin C. Yoder, Matthias Clauss, Robert J. Freish...> ;Scientific Reports. 2020 Jan 24
• 9 citations
  Muc5b Enhances Murine Honeycomb-like Cyst Formation
  Jonathan S. Kurche, Evgenia Dobrinskikh, Corinne E. Hennessy, Alani Estrella, Laura A. Hancock, Marvin I. Schwarz, Tsukasa Okamoto, Carlyne D. Cool, Ivana V. Yang, Chr...> ;American Journal of Respiratory Cell and Molecular Biology. 2019 Oct 1
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Journal Articles

• Familial idiopathic interstitial pneumonia: histopathology and survival in 30 patients.  
  Leslie KO, Cool CD, Sporn TA, Curran-Everett D, Steele MP, Brown KK, Wahidi MM, Schwartz DA, Archives of Pathology & Laboratory Medicine, 11/1/2012
• Severe pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization.  
  Mizuno S, Farkas L, al Husseini A, Farkas D, Gomez-Arroyo J, Kraskauskas D, Nicolls MR, Cool CD, Bogaard HJ, Voelkel NF, American Journal of Respiratory Cell & Molecular Biology, 11/1/2012
• MicroRNA-199A-5p is associated with hypoxia-inducible factor-1 expression in lungs from patients with COPD.  
  Mizuno S, Bogaard HJ, Gomez-Arroyo J, Alhussaini A, Kraskauskas D, Cool CD, Voelkel NF, Chest, 9/1/2012
• Modern age of pathology of pulmonary arterial hypertension.  
  Stacher E, Graham BB, Hunt J, Gandjeva A, Groshong SD, McLaughlin VV, Jessup M, Grizzle WE, Aldred MA, Cool CD, Tuder RM, Am J Resp & Crit Care Med, 8/1/2012
• Viral infection and pulmonary hypertension: is there an association?  
  Cool CD, Voelkel NF, Bull T, Expert Review of Respiratory Medicine, 4/1/2011
• Hypoxia-inducible factor-1alpha in human emphysema lung tissue.  
  Yasuo M, Mizuno S, Kraskauskas D, Bogaard HJ, Natarajan R, Cool CD, Zamora M, Voelkel NF, European Respiratory Journal, 4/1/2011
• Decreased neprilysin and pulmonary vascular remodeling in chronic obstructive pulmonary disease.  
  Wick MJ, Buesing EJ, Wehling CA, Loomis ZL, Cool CD, Zamora MR, Miller YE, Colgan SP, Hersh LB, Voelkel NF, Dempsey EC, AJRCCM, 2/1/2011
• A 31-year-old woman with hemoptysis and an intrathoracic mass.  
  Macht M. Mitchell JD. Cool C. Lynch DA. Babu A. Schwarz MI, Chest, 7/1/2010
• Formation of plexiform lesions in experimental severe pulmonary arterial hypertension.  
  Abe K. Toba M. Alzoubi A. Ito M. Fagan KA. Cool CD. Voelkel NF. McMurtry IF. Oka M, Circulation, 6/29/2010
• Compartmentalized expression of c-FLIP in lung tissues of patients with idiopathic pulmonary fibrosis.  
  Cha SI. Groshong SD. Frankel SK. Edelman BL. Cosgrove GP. Terry-Powers JL. Remigio LK. Curran-Everett D. Brown KK. Cool CD. Riches DW, American Journal of Respiratory Cell & Molecular Biology, 2/1/2010
• Pathologic patterns and survival in chronic hypersensitivity pneumonitis.  
  Churg A. Sin DD. Everett D. Brown K. Cool C, American Journal of Surgical Pathology, 12/1/2009
• Murine gammaherpesvirus 68 infection of gamma interferon-deficient mice on a BALB/c background results in acute lethal pneumonia that is dependent on specific viral ge...  
  Lee KS. Cool CD. van Dyk LF, Journal of Virology, 11/1/2009
• Minor salivary gland biopsy to detect primary Sjogren syndrome in patients with interstitial lung disease.  
  Fischer A. Swigris JJ. du Bois RM. Groshong SD. Cool CD. Sahin H. Lynch DA. Gillis JZ. Cohen MD. Meehan RT. Brown KK, Chest, 10/1/2009
• Murine gammaherpesvirus 68 infection of IFNgamma unresponsive mice: a small animal model for gammaherpesvirus-associated B-cell lymphoproliferative disease.  
  Lee KS. Groshong SD. Cool CD. Kleinschmidt-DeMasters BK. van Dyk LF, Cancer Research, 7/1/2009
• Immunopathology of chronic rhinosinusitis in young children.  
  Coffinet L. Chan KH. Abzug MJ. Simoes EA. Cool C. Liu AH, Journal of Pediatrics, 5/1/2009
• Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia.  
  Dempsey EC. Wick MJ. Karoor V. Barr EJ. Tallman DW. Wehling CA. Walchak SJ. Laudi S. Le M. Oka M. Majka S. Cool CD. Fagan KA. Klemm DJ. Hersh LB. Gerard NP. Gerard C. ..., American Journal of Pathology, 3/1/2009
• Exposure-related diffuse lung disease.  
  Rose CS. Lynch DA. Cool CD, Seminars in Respiratory & Critical Care Medicine, 12/1/2008
• The cancer paradigm of severe pulmonary arterial hypertension.  
  Rai PR. Cool CD. King JA. Stevens T. Burns N. Winn RA. Kasper M. Voelkel NF, American Journal of Respiratory & Critical Care Medicine, 9/15/2008
• From viral infection to pulmonary arterial hypertension: a role for viral proteins?  
  Voelkel NF. Cool CD. Flores S, AIDS, 9/1/2008
• Clinically significant interstitial lung disease in limited scleroderma: histopathology, clinical features, and survival.  
  Fischer A. Swigris JJ. Groshong SD. Cool CD. Sahin H. Lynch DA. Curran-Everett D. Gillis JZ. Meehan RT. Brown KK, Chest, 9/1/2008
• Abrogation of anti-inflammatory transcription factor LKLF in neutrophil-dominated airways.  
  Saavedra MT. Patterson AD. West J. Randell SH. Riches DW. Malcolm KC. Cool CD. Nick JA. Dinarello CA, American Journal of Respiratory Cell & Molecular Biology, 6/1/2008
• Pulmonary arterial hypertension from a pediatric perspective.  
  Cool CD. Deutsch G, Pediatric & Developmental Pathology, 5/1/2008
• Wheezing and exertional dyspnea in a 25-year-old mountaineer.  
  Young RL. Mitchell JD. Cool C. Nana-Sinkam SP, Chest, 3/1/2008
• VEGF-R blockade causes endothelial cell apoptosis, expansion of surviving CD34+ precursor cells and transdifferentiation to smooth muscle-like and neuronal-like cells.  
  Sakao, Seiichiro. Taraseviciene-Stewart, Laimute. Cool, Carlyne D. Tada, Yuji. Kasahara, Yasunori. Kurosu, Katsushi. Tanabe, Nobuhiro. Takiguchi, Yuichi. Tatsumi, Koic..., FASEB J, 11/1/2007
• Plexiform-like lesions and increased tissue factor expression in a rat model of severe pulmonary arterial hypertension.  
  White, R James. Meoli, David F. Swarthout, Robert F. Kallop, Dara Y. Galaria, Irfan I. Harvey, Jennifer L. Miller, Christine M. Blaxall, Burns C. Hall, Carla M. Pierce..., Am J Physiol Lung Cell Mol Physiol, 9/1/2007
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Books/Book Chapters

• Imaging of Diffuse Lung Disease 
  Chapter: Pathologic evaluation of interstitial lung disease. 
  Page 21 - 33Tuder RM, Cool CDEditors: DA Lynch, JD Newell, Jr., JS Lee.BC Decker, Inc., Hamilton, London2000
• Interstitial Lung Disease 
  Chapter: Pulmonary vascular involvement in interstitial lung disease (ILD). 
  Page 251 - 263Tuder RM, Cool C, Jennings C and Voelkel NFEditors: MI Schwarz, T King, Jr..BC Decker, Inc., OntarioEdition 3rd ,1998

Abstracts/Posters

• HHV-8 Expression in Primary Pulmonary Hypertension.
  Cool CD, Rai PR, Yeager ME, Serls AE, Bull TM, Brown KK, Routes JM, Tuder RM, Voelkel NF, 3rd World Symposium on Pulmonary Hypertension, Venice, 6/1/2003
• Transdifferentiation of Endothelial Cells in Primary Pulmonary Hypertension.
  Cool CD, Wood K, Voelkel NF, ATS International Conference, Seattle, WA, 5/1/2003
• Vascular alterations associated with usual interstitial pneumonia (UIP)
  Portnoy J, Schwarz MI, Brown KK, Kossack W, Cool CD, ATS International Conference, Seattle, WA, 5/1/2003
• Chronic Rhinosinusitis In Young Children Differs From Adults: A Histopathology Study
  KH Chan, MJ Abzug, L Coffinet, EAF Simoes, C Cool, JY Wescott, AH Liu, AAI Meeting, Denver, CO, 3/1/2003
• Increased infections with herpes virus 8 (HHV8) in patients with common variable immunodeficiency (CVID) and lymphoproliferative disorders.
  Wheat W. Kirkpatrick C, Brown K, Bates C, Cool C, Serls A, Rai P, Routes J, AAI Meeting, Denver, CO, 3/1/2003
• Evidence for plexiform lesions in the lungs of macaques infected with simian immunodeficiency virus.
  Marecki, J.C., Cool, C.D., Voelkel, N.F., Carville, A., Flores, S.C., 99th International American Thoracic Society Conference, Seattle, WA, 1/1/2003
• Determinants of Survival in Fibrotic Hypersensitivity Pneumonitis.
  Vourlekis JS, Schwarz MI, Cherniack RM, Durran-Everett D, Cool CD, Tuder RM, King TE, Brown KK, ATS International Conference, Atlanta, GA, 5/1/2002
• An Immunohistochemical Analysis of GM-CSF in Pulmonary Alveolar Proteinosis.
  Vourlekis JS, Cool CD, Colby TV, Yousem SA, Schwarz MI, Brown KK, ATS International Conference, Atlanta, GA, 5/1/2002
• Modeling of intravascular pulmonary endothelial cell proliferation in severe pulmonary hypertension.
  Cool CD, Geraci MW, Hoshikawa Y, Kasahara Y, Chan D., Voelkel NF, Tuder RM, ATS International Conference, San Francisco, CA, 5/1/2001
• Nonspecific Interstitial Pneumonitis (NSIP) Can Be the Sole Histopathologic Lesion of Hypersensitivity Pneumonitis (HP).
  Vourlekis JS, Brown KK, Cool CD, Tuder RM, King Jr. TE, Schwarz MI, ATS International Conference, San Francisco, CA, 5/1/2001
• Does Pulmonary Fibrosis Influence Survival in Hypersensitivity Pneumonitis?
  Vourlekis JS, Brown KK, Cool CD, Tuder RM, King Jr. TE, Schwarz MI, ATS International Conference, San Francisco, CA, 5/1/2001
• Inflammatory myofibroblastic tumor (IMT) presenting as a component or as a pure type of pulmonary artery sarcoma.
  Yi ES, Jacobson D, Sneider W, Cool CD, United States and Canadian Academy of Pathology (USCAP), Boston, MA, 1/1/2001
• Recurrent Acute Interstitial Pneumonitis.
  Vourlekis JS, Brown KK, King TE Jr., Cool CD, Schwarz MI, Am J Respir Crit Care Med, 1/1/2000
• Monoclonal endothelial cell proliferation is present in primary but not secondary pulmonary hypertension.
  Lee S-D, Shroyer KR, Markham NE, Cool CD, Voelkel NF and Tuder RM, ATS International Conference, Chicago, IL, 5/1/1998
• VEGF receptor (KDR) and p27/kip1 3-dimensional mapping in plexiform lesions of pulmonary hypertension.
  Cool CD, Stewart JS, Werahera P, Miller G, Voelkel NF and Tuder RM, ATS International Conference, Chicago, IL, 5/1/1998
• Computer-aided 3-dimensional reconstruction study of plexiform lesions in pulmonary hypertension.
  Cool CD, Stewart JS, Werahera P, Miller G, Voelkel N and Tuder R, International Academy of Pathology National Meeting, Boston, MA, 3/1/1998
• Expression of nitric oxide synthase in endothelium grown in an artificial capillary system - a new model for plexiform lesions found in pulmonary hypertension
  Orte C, Bishop AE, Mason NA, Cool CD, Tuder RM, Pollock JS and Polak JM, 1/1/1998
• Low or absent peptidase expression in plexiform lesions of primary pulmonary hypertension (PPH).
  Cohen AJ, Cool C, Gilman L, Tuder R, Miller Y and Voelkel N, Aspen Lung Conference, 1/1/1997
• Endothelin-1 (ET-1) is upregulated in respiratory bronchiolitis-interstitial lung disease (RB-ILD).
  Cohen AJ, King TE, Cool C and Miller YE, Am J Respir and Crit Care Med, 1/1/1997
• Aminopeptidase N (APN) and angiotensin-converting enzyme (ACE) expression in patients with primary pulmonary hypertension (PPH).
  Cohen AJ, Miller Y, Cool C, Garg S, Gilman L and Voelkel N, Am J Respir and Crit Care Med, 1/1/1997
• Prostacyclin synthase expression is decreased in lungs with severe pulmonary hypertension.
  Tuder RM, Wang J, Cool CD, Wright L, Geraci MW, Badesch DB and Voelkel NF, Am J Respir and Crit Care Med, 1/1/1997
• Expression of protein kinases in bovine pulmonary endothelial cells in a capillary cell system (CellMax) under conditions of high shear stress.
  SD Lee, Cool CD, Wang J, Tuder RM and Voelkel NF, Am J Respir and Crit Care Med, 1/1/1997
• Analysis of vascular lesions in familial primary pulmonary hypertension (FPPH): Insights into the endothelial cell as the common denominator of a morphologically heter...
  Cool CD, Voelkel NF, Loyd J, Wheeler L and Tuder RM, Am J Respir and Crit Care Med, ATS International Conference, San Francisco, CA, 1/1/1997
• Differentiation of endothelial cells in a novel in vitro flow system.
  Cool CD, Kressin D, Hassell K, Welsh C, Voelkel NF and Tuder RM, Am J Respir and Crit Care Med, ATS International Conference, San Francisco, CA, 1/1/1997
• Three-dimensional reconstruction of the plexiform lesions in pulmonary hypertension.
  Cool CD, Voelkel NF and Tuder RM, Am Rev Respir Dis, ATS International Conference, New Orleans, LA, 6/1/1996
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Other

• Idiopathic interstitial pneumonias: Clinical manifestations and pathology 
  Cool CD
  http://www.uptodate.com/contents/idiopathic-interstitial-pneumonias-clinical-manifestations-and-path
  UpToDate, Wolters Kluwer Health - 2012-05-08