CarolAAghajanianMD

PubMed

• Phase II trial of pembrolizumab and epacadostat in recurrent clear cell carcinoma of the ovary: An NRG oncology study GY016.
  Lilian T Gien, Danielle M Enserro, Linda R Duska, Andrea E Wahner-Hendrickson, Premal H Thaker, Allan Covens, Kathleen N Moore, Robert L Coleman, Matthew S Block, Stev...> ;Gynecologic Oncology. 2024 Apr 10
• Mainstreaming in parallel with ovarian cancer tumor testing to improve genetic testing uptake.
  Maureen Byrne, Tiffany Y Sia, Christopher Fong, Aliya Khurram, Michele Waters, Yelena M Kemel, Qin Zhou, Megha Ranganathan, Kara Long Roche, Dennis S Chi, Sally Saban,...> ;Gynecologic Oncology. 2024 Mar 14
• A phase 2 trial of zanidatamab in HER2-overexpressed advanced endometrial carcinoma and carcinosarcoma (ZW25-IST-2).
  Melissa Lumish, M Herman Chui, Qin Zhou, Alexia Iasonos, Debra Sarasohn, Seth Cohen, Claire Friedman, Rachel Grisham, Jason Konner, Chrisann Kyi, Maria Rubinstein, Tif...> ;Gynecologic Oncology. 2024 Mar 1
• Mesonephric and mesonephric-like adenocarcinomas of gynecologic origin: A single-center experience with molecular characterization, treatment, and oncologic outcomes.
  Aaron M Praiss, Charlie White, Alexia Iasonos, Pier Selenica, Oliver Zivanovic, Dennis S Chi, Nadeem R Abu-Rustum, Britta Weigelt, Carol Aghajanian, Jeffrey Girshman, ...> ;Gynecologic Oncology. 2024 Mar 1
• 1 citations
  Evaluation of potential biomarkers for lenvatinib plus pembrolizumab among patients with advanced endometrial cancer: results from Study 111/KEYNOTE-146.
  Makker, V., Taylor, M., Aghajanian, C., Cohn, A., Brose, M., Simone, C., Cao, Z., Suttner, L., Loboda, A., Cristescu, R., Jelinic, P., Orlowski, R., Dutta, L., Matsui,...> ;Journal for Immunotherapy of Cancer. 2024 Jan 19
• Pathogenic germline variants in non-BRCA1/2 homologous recombination genes in ovarian cancer: Analysis of tumor phenotype and survival.
  Kahn, R., Selenica, P., Boerner, T., Roche, K., Xiao, Y., Sia, T., Maio, A., Kemel, Y., Sheehan, M., Salo-Mullen, E., Breen, K., Zhou, Q., Iasonos, A., Grisham, R., O'...> ;Gynecologic Oncology. 2024 Jan 1
• Transforming ovarian cancer care by targeting minimal residual disease.
  Amir A Jazaeri, Rachel Grisham, Anne Knisely, Stefani Spranger, Dmitriy Zamarin, R Tyler Hillman, Barrett C Lawson, Kathleen H Burns, Sanghoon Lee, Shannon N Westin, E...> ;Med. 2023 Nov 10
• 3 citations
  Pathogenic germline variants in patients with endometrial cancer of diverse ancestry.
  Ying L Liu, Sushmita Gordhandas, Kanika Arora, Eric Rios-Doria, Karen A Cadoo, Amanda Catchings, Anna Maio, Yelena Kemel, Margaret Sheehan, Erin Salo-Mullen, Qin Zhou,...> ;Cancer. 2024 Feb 15
• TERT promoter mutations and gene amplification in endometrial cancer.
  Aaron M Praiss, Antonio Marra, Qin Zhou, Eric Rios-Doria, Amir Momeni-Boroujeni, Alexia Iasonos, Pier Selenica, David N Brown, Carol Aghajanian, Nadeem R Abu-Rustum, L...> ;Gynecologic Oncology. 2023 Dec 1
• Adverse events and oncologic outcomes with combination lenvatinib and pembrolizumab for the treatment of recurrent endometrial cancer.
  William A Zammarrelli 3rd, Weining Ma, Kevin Espino, Sushmita Gordhandas, Effi Yeoshoua, Sarah Ehmann, Qin Zhou, Alexia Iasonos, Nadeem R Abu-Rustum, Carol Aghajanian,...> ;Gynecologic Oncology. 2023 Nov 1
• 1 citations
  Germline Pathogenic Variants and Genetic Counseling by Ancestry in Patients With Epithelial Ovarian Cancer.
  Tiffany Y Sia, Anna Maio, Yelena M Kemel, Kanika S Arora, Sushmita B Gordhandas, Ryan M Kahn, Erin E Salo-Mullen, Margaret A Sheehan, Prince Rainier Tejada, Chaitanya ...> ;JCO Precision Oncology. 2023 Sep 1
• 4 citations
  Molecular Characterization of Endometrial Carcinomas in Black and White Patients Reveals Disparate Drivers with Therapeutic Implications.
  Britta Weigelt, Antonio Marra, Pier Selenica, Eric Rios-Doria, Amir Momeni-Boroujeni, Michael F Berger, Kanika Arora, David Nemirovsky, Alexia Iasonos, Debyani Chakrav...> ;Cancer Discovery. 2023 Nov 1
• Assessing the Genomic Landscape of Cervical Cancers: Clinical Opportunities and Therapeutic Targets.
  Claire F Friedman, Vignesh Ravichandran, Kathryn Miller, Chad Vanderbilt, Qin Zhou, Alexia Iasonos, Malavika Vivek, Pamela Mishra, Mario M Leitao Jr, Vance Broach, Yuk...> ;Clinical Cancer Research. 2023 Nov 14
• 1 citations
  Overall survival and patient-reported outcome results from the placebo-controlled randomized phase III IMagyn050/GOG 3015/ENGOT-OV39 trial of atezolizumab for newly di...
  Sandro Pignata, Michael Bookman, Jalid Sehouli, Austin Miller, Richard T Penson, Cagatay Taskiran, Charles Anderson, Sakari Hietanen, Tashanna Myers, Radoslaw Madry, L...> ;Gynecologic Oncology. 2023 Oct 1
• 1 citations
  Molecular Results and Potential Biomarkers Identified from the Phase 3 MILO/ENGOT-ov11 Study of Binimetinib versus Physician Choice of Chemotherapy in Recurrent Low-Gr...
  Rachel N Grisham, Ignace Vergote, Susana Banerjee, Esther Drill, Elsa Kalbacher, Mansoor Raza Mirza, Ignacio Romero, Peter Vuylsteke, Robert L Coleman, Felix Hilpert, ...> ;Clinical Cancer Research. 2023 Oct 13
• 1 citations
  Response to Letter to the Editor, Gilks et al.
  Britta Weigelt, Jennifer J Mueller, Lora H Ellenson, Nadeem R Abu-Rustum, Carol Aghajanian> ;Gynecologic Oncology. 2023 Sep 1
• A phase 2 study of dasatinib in recurrent clear cell carcinoma of the ovary, fallopian tube, peritoneum or endometrium: NRG oncology/gynecologic oncology group study 0...
  Roisin E O'Cearbhaill, Austin Miller, Robert A Soslow, Heather A Lankes, Deborah DeLair, Sheila Segura, Shweta Chavan, Dmitriy Zamarin, Robert DeBernardo, Kathleen Moo...> ;Gynecologic Oncology. 2023 Sep 1
• 13 citations
  Integration of clinical sequencing and immunohistochemistry for the molecular classification of endometrial carcinoma.
  Eric Rios-Doria, Amir Momeni-Boroujeni, Claire F Friedman, Pier Selenica, Qin Zhou, Michelle Wu, Antonio Marra, Mario M Leitao Jr, Alexia Iasonos, Kaled M Alektiar, Yu...> ;Gynecologic Oncology. 2023 Jul 1
• Carboplatin dosing in the treatment of ovarian cancer: An NRG oncology group study.
  Aaron M Praiss, Austin Miller, Judith Smith, Stuart M Lichtman, Michael Bookman, Carol Aghajanian, Paul Sabbatini, Floor Backes, David E Cohn, Peter Argenta, Michael F...> ;Gynecologic Oncology. 2023 Jul 1
• 3 citations
  Germline drivers of gynecologic carcinosarcomas.
  Tiffany Y Sia, Sushmita B Gordhandas, Ozge Birsoy, Yelena Kemel, Anna Maio, Erin Salo-Mullen, Margaret Sheehan, Martee L Hensley, Maria Rubinstein, Vicky Makker, Rache...> ;Gynecologic Oncology. 2023 Jul 1
• 84 citations
  Pembrolizumab plus Chemotherapy in Advanced Endometrial Cancer.
  Ramez N Eskander, Michael W Sill, Lindsey Beffa, Richard G Moore, Joanie M Hope, Fernanda B Musa, Robert Mannel, Mark S Shahin, Guilherme H Cantuaria, Eugenia Girda, C...> ;The New England Journal of Medicine. 2023 Jun 8
• 2 citations
  Chemotherapy response in low-grade serous ovarian carcinoma at a comprehensive cancer center: Readdressing the roles of platinum and cytotoxic therapies.
  Beryl L Manning-Geist, Ryan M Kahn, David Nemirovsky, Jeffrey Girshman, Anya Laibangyang, Sushmita Gordhandas, Alexia Iasonos, M Herman Chui, Kara Long Roche, Oliver Z...> ;Cancer. 2023 Jul 1
• 3 citations
  Landscape of chromatin remodeling gene alterations in endometrial carcinoma.
  Amir Momeni-Boroujeni, Chad Vanderbilt, Elham Yousefi, Nadeem R Abu-Rustum, Carol Aghajanian, Robert A Soslow, Lora H Ellenson, Britta Weigelt, Rajmohan Murali> ;Gynecologic Oncology. 2023 May 1
• 4 citations
  Comprehensive analysis of germline drivers in endometrial cancer.
  Sushmita Gordhandas, Eric Rios-Doria, Karen A Cadoo, Amanda Catchings, Anna Maio, Yelena Kemel, Margaret Sheehan, Megha Ranganathan, Dina Green, Anjali Aryamvally, Ang...> ;Journal of the National Cancer Institute. 2023 May 8
• 2 citations
  Predicting outcomes in female germ cell tumors using a modified International Germ Cell Cancer Collaborative Group classification system to guide management.
  Ying L Liu, Beryl L Manning-Geist, Andrea Knezevic, Luxue Deng, Maria Bromberg, Samuel A Funt, Jane L Meisel, Oliver Zivanovic, Kara Long Roche, Yukio Sonoda, Ginger J...> ;Gynecologic Oncology. 2023 Mar 1
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Journal Articles

• A Phase 1 Dose-Escalation Study of Intraperitoneal Cisplatin, intravenous/intraperitoneal Paclitaxel, Bevacizumab, and Olaparib for Newly Diagnosed Ovarian Cancer  
  Karen A Cadoo, Roisin E O'Cearbhaill, Dmitriy Zamarin, Paul J Sabbatini, William P Tew, Carol Aghajanian, Jason A Konner, Gynecologic Oncology
• Maintenance Olaparib in Patients with Newly Diagnosed Advanced Ovarian Cancer  
  Kathleen Moore, Paul DiSilvestro, Carol Aghajanian, The New England Journal of Medicine

Lectures

• Targeted Agents: Finding the Mark 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/4/2018
• Evaluation of rucaparib in platinum-sensitive recurrent ovarian carcinoma (rOC) in patients (pts) with or without residual bulky disease at baseline in the ARIEL3 study. 
  2018 ASCO Annual Meeting - Chicago, Illinois - 06/4/2018
• Scientific and Clinical Update in Gynecologic Oncology 
  Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania - 5/3/2013