CarolinaGutierrezMD

PubMed

• High FOXA1 levels induce ER transcriptional reprogramming, a pro-metastatic secretome, and metastasis in endocrine-resistant breast cancer.
  Xiaoyong Fu, Resel Pereira, Chia-Chia Liu, Carmine De Angelis, Martin J Shea, Sarmistha Nanda, Lanfang Qin, Tamika Mitchell, Maria L Cataldo, Jamunarani Veeraraghavan,...> ;Cell Reports. 2023 Aug 29
• 15 citations
  Systematically higher Ki67 scores on core biopsy samples compared to corresponding resection specimen in breast cancer: a multi-operator and multi-institutional study.
  Balazs Acs, Samuel C Y Leung, Kelley M Kidwell, Indu Arun, Renaldas Augulis, Sunil S Badve, Yalai Bai, Anita L Bane, John M S Bartlett, Jane Bayani, Gilbert Bigras, An...> ;Modern Pathology. 2022 Oct 1
• 3 citations
  Neratinib plus trastuzumab is superior to pertuzumab plus trastuzumab in HER2-positive breast cancer xenograft models
  Jamunarani Veeraraghavan, Carolina Gutierrez, Vidyalakshmi Sethunath, Sepideh Mehravaran, Mario Giuliano, Martin Shea, Tamika Mitchell, Tao Wang, Sarmistha Nanda, Rese...> ;NPJ Breast Cancer. 2021 May 27
• 43 citations
  Fecal microbiota transplantation in HIV: A pilot placebo-controlled study
  Sergio Serrano-Villar, Alba Talavera-Rodríguez, María José Gosalbes, Nadia Madrid, José A. Pérez-Molina, Ryan J. Elliott, Beatriz Navia, Val F. Lanza, Alejandro Vallej...> ;Nature Communications. 2021 Feb 18
• 10 citations
  Effect of the use of Galectin-9 and blockade of TIM-3 receptor in the latent cellular reservoir of HIV-1.
  Marta Sanz, Nadia Madrid-Elena, Sergio Serrano-Villar, Alejandro Vallejo, Carolina Gutierrez, Santiago Moreno> ;Journal of Virology. 2021 Feb 10
• 6 citations
  Prolonged administration of maraviroc reactivates latent HIV in vivo but it does not prevent antiretroviral-free viral rebound.
  María Rosa López-Huertas, Carolina Gutierrez, Nadia Madrid-Elena, Beatriz Hernández-Novoa, Julián Olalla-Sierra, Montserrat Plana, Rafael Coll Delgado, Rafael M. Rubio...> ;Scientific Reports. 2020 Dec 18
• Impact of surgery on the mortality of infective endocarditis in a hospital without cardiac surgery
  Rosa Escudero-Sánchez, S. Scarleth Mendoza Lizardo, Elena Batlle López, Carolina Gutierrez, Juan Emilio Losa García, María Velasco Arribas> ;Revista Espanola De Quimioterapia. 2020 Oct 13
• 5 citations
  Maraviroc reactivates HIV with potency similar to that of other latency reversing drugs without inducing toxicity in CD8 T cells.
  María Rosa López-Huertas, Laura Jiménez-Tormo, Nadia Madrid-Elena, Carolina Gutierrez, María J Vivancos, Laura Luna, Santiago Moreno> ;Biochemical Pharmacology. 2020 Sep 23
• 31 citations
  TBCRC023: A Randomized Phase II Neoadjuvant Trial of Lapatinib Plus Trastuzumab Without Chemotherapy for 12 versus 24 Weeks in Patients with HER2-Positive Breast Cancer.
  Mothaffar F. Rimawi, Polly A. Niravath, Tao Wang, Brent N. Rexer, Andres Forero, Antonio C. Wolff, Rita Nanda, Anna Maria Storniolo, Ian E. Krop, Matthew P. Goetz, Jul...> ;Clinical Cancer Research. 2020 Feb 15
• 26 citations
  Evaluation of the Predictive Role of Tumor Immune Infiltrate in Patients with HER2-Positive Breast Cancer Treated with Neoadjuvant Anti-HER2 Therapy without Chemotherapy.
  Carmine De Angelis, Chandandeep Nagi, Cliff Hoyt, Linying Liu, Kristin Roman, Chichung Wang, Yi Zheng, Jamunarani Veeraraghavan, Vidyalakshmi Sethunath, Paolo Nuciforo...> ;Clinical Cancer Research. 2020 Feb 1
• 92 citations
  HER2-Enriched Subtype and ERBB2 Expression in HER2-Positive Breast Cancer Treated with Dual HER2 Blockade.
  Aleix Prat, Tomás Pascual, Carmine De Angelis, Carolina Gutierrez, Antonio Llombart-Cussac, Tao Wang, Javier Cortes, Brent N. Rexer, Laia Paré, Andres Forero, Antonio ...> ;Journal of the National Cancer Institute. 2020 Jan 1
• 83 citations
  FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer
  Xiaoyong Fu, Resel Pereira, Carmine De Angelis, Jamunarani Veeraraghavan, Sarmistha Nanda, Lanfang Qin, Maria Letizia Cataldo, Vidyalakshmi Sethunath, Sepideh Mehravar...> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Dec 11
• 7 citations
  Selective miRNA Modulation Fails to Activate HIV Replication in In Vitro Latency Models
  María Rosa López-Huertas, Matías Morín, Nadia Madrid-Elena, Carolina Gutierrez, Laura Jiménez-Tormo, Javier Santoyo, Francisco Sanz-Rodríguez, Miguel Ángel Moreno Pela...> ;Molecular Therapy. Nucleic Acids. 2019 Sep 6
• 61 citations
  Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicentre collabora...
  Samuel C Y Leung, Torsten O. Nielsen, Lila Zabaglo, Indu Arun, Sunil Badve, Anita Bane, John M. S. Bartlett, Signe Borgquist, Martin C. Chang, Andrew Dodson, Anna Ehin...> ;Histopathology. 2019 Aug 1
• 32 citations
  A combinatorial biomarker predicts pathologic complete response to neoadjuvant lapatinib and trastuzumab without chemotherapy in patients with HER2+ breast cancer
  Jamunarani Veeraraghavan, C. De Angelis, R. Mao, Ting Wang, Sabrina Herrera, Anna C. Pavlick, Alejandro Contreras, Paolo Nuciforo, Ingrid A. Mayer, Andres Forero, Rita...> ;Annals of Oncology. 2019 Jun 1
• 6 citations
  High CD8 T cell percentage and HCV replication control are common features in HIV-1 controllers and HTLV-2-co-infected patients with a history of injection drug use.
  Ezequiel Ruiz-Mateos, María J. Ruiz-León, Laura Tarancon-Diez, Carolina Gutierrez, Fernando Dronda, Beatriz Dominguez-Molina, María J Pérez-Elías, Ana Moreno, Manuel L...> ;Virus Research. 2019 Apr 15
• 9 citations
  Analysis of the dysregulation between regulatory B and T cells (Breg and Treg) in human immunodeficiency virus (HIV)-infected patients.
  Carolina Gutierrez, Jacobo López-Abente, Verónica Astrid Pérez-Fernández, Adrián Prieto-Sánchez, Rafael Correa-Rocha, Santiago Moreno-Guillen, M. A. Muñoz-Fernández, M...> ;Plos One. 2019 Mar 27
• 63 citations
  Low PTEN levels and PIK3CA mutations predict resistance to neoadjuvant lapatinib and trastuzumab without chemotherapy in patients with HER2 over-expressing breast cancer
  Mothaffar F. Rimawi, Carmine De Angelis, Alejandro Contreras, Fresia Pareja, Felipe C Geyer, Kathleen A. Burke, Sabrina Herrera, Tao Wang, Ingrid A. Mayer, Andres Fore...> ;Breast Cancer Research and Treatment. 2018 Nov 7
• 19 citations
  CD72/CD100 and PD-1/PD-L1 markers are increased on T and B cells in HIV-1+ viremic individuals, and CD72/CD100 axis is correlated with T-cell exhaustion.
  Rafael Correa-Rocha, Jacobo López-Abente, Carolina Gutierrez, Verónica Astrid Pérez-Fernández, Adrián Prieto-Sánchez, Santiago Moreno-Guillen, M. A. Muñoz-Fernández, M...> ;Plos One. 2018 Aug 30
• 43 citations
  Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer.
  Amritha Nair, Hsiang Ching Chung, Tingting Sun, Siddhartha Tyagi, Lacey E. Dobrolecki, Rocio Dominguez-Vidana, Sarah J. Kurley, Mayra Orellana, Alexander Renwick, Davi...> ;Nature Medicine. 2018 Mar 26
• 73 citations
  HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer
  Xiaowei Xu, Carmine De Angelis, Kathleen A. Burke, Agostina Nardone, Huizhong Hu, Lanfang Qin, Jamunarani Veeraraghavan, Vidyalakshmi Sethunath, Laura M. Heiser, Nicho...> ;Clinical Cancer Research. 2017 Sep 1
• 34 citations
  The CCR5-antagonist Maraviroc reverses HIV-1 latency in vitro alone or in combination with the PKC-agonist Bryostatin-1
  María Rosa López-Huertas, Laura Jiménez-Tormo, Nadia Madrid-Elena, Carolina Gutierrez, Sara Rodríguez-Mora, Mayte Coiras, José Alcamí, Santiago Moreno> ;Scientific Reports. 2017 May 24
• 9 citations
  Multiple clear cell acanthomas and a sebaceous lymphadenoma presenting in a patient with Cowden syndrome - a case report.
  Silvia Potenziani, Danielle S. Applebaum, Bhuvaneswari Krishnan, Carolina Gutierrez, A. Hafeez Diwan> ;Journal of Cutaneous Pathology. 2017 Jan 1
• 99 citations
  FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer
  Xiaoyong Fu, Rinath Jeselsohn, Resel Pereira, Emporia F Hollingsworth, Chad J. Creighton, Fugen Li, Martin Shea, Agostina Nardone, Carmine De Angelis, Laura M. Heiser,...> ;Proceedings of the National Academy of Sciences of the United States of America. 2016 Oct 25
• 96 citations
  Analytical validation of a standardized scoring protocol for Ki67: phase 3 of an international multicenter collaboration.
  Samuel C Y Leung, Torsten O. Nielsen, Lila Zabaglo, Indu Arun, Sunil Badve, Anita Bane, John M. S. Bartlett, Signe Borgquist, Martin C. Chang, Andrew Dodson, Rebecca A...> ;NPJ Breast Cancer. 2016 May 18
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