CatherineAnneChappellMD

Obstetrics & Gynecology • Pittsburgh, PA

Instructor, Ob/Gyn & Reproductive Science, University of Pittsburgh School of Medicine

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Office
300 Halket Street
Suite 0610
Pittsburgh, PA 15213
Phone+1 412-641-6412

Fax+1 412-641-6512
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Education & Training

University of Texas Southwestern Medical CenterResidency, Obstetrics and Gynecology, 2007 - 2011
University of Texas Southwestern Medical SchoolClass of 2007

Certifications & Licensure

PA State Medical License 2011 - 2024
American Board of Obstetrics and Gynecology Obstetrics & Gynecology
American Board of Preventive Medicine Addiction Medicine

Clinical Trials

A Pharmacokinetic Evaluation of Etonogestrel (ENG) Implant and Antiretroviral Therapy Start of enrollment: 2014 Oct 01
Completed
Phase 4
Study of Hepatitis C Treatment During Pregnancy Start of enrollment: 2016 Sep 01
Completed
Phase 1
Pharmacologic Strategies for the Etonogestrel Implant in HIV-Infected Women Start of enrollment: 2019 Feb 19
Completed
Phase 2
Treatment of Chronic Hepatitis C During Pregnancy With Sofosbuvir/Velpatasvir Start of enrollment: 2020 Oct 22
Completed
Phase 1
Sofosbuvir/Velpatasvir Treatment of Chronic Hepatitis C During Pregnancy Start of enrollment: 2022 Apr 04
Recruiting
Phase 4
Roles: Principal Investigator, Contact, Sponsor-Investigator
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Publications & Presentations

PubMed

A randomized trial of double vs single-dose etonogestrel implant to overcome the interaction with efavirenz-based antiretroviral therapy.
Catherine A Chappell, Mohammed Lamorde, Shadia Nakalema, Isabella Kyohairwe, Pauline Byakika-Kibwika, Leslie A Meyn, Michelle M Pham, Kimberly K Scarsi> ;American Journal of Obstetrics and Gynecology. 2024 Mar 7
Postpartum Treatment for Chronic Hepatitis C Virus Among People With Opioid Use Disorder: A Prospective Pilot Clinical Trial.
Stewart, E., Laird, H., Jonassaint, N., Kasula, K., Patterson, M., Krans, E., Chappell, C.> ;Journal of Addiction Medicine. 2024 Jan 22
1 citations
DELIVER: A Safety Study of a Dapivirine Vaginal Ring and Oral PrEP for the Prevention of HIV During Pregnancy.
Katherine Bunge, Jennifer E Balkus, Lee Fairlie, Ashley J Mayo, Clemensia Nakabiito, Nyaradzo Mgodi, Luis Gadama, Moleen Matrimbira, Catherine Anne Chappell, Jeanna Pi...> ;Journal of Acquired Immune Deficiency Syndromes. 2024 Jan 1
DELIVER: A Safety Study of a Dapivirine Vaginal Ring and Oral PrEP for the Prevention of HIV During Pregnancy.
Katherine Bunge, Jennifer E Balkus, Lee Fairlie, Ashley J Mayo, Clemensia Nakabiito, Nyaradzo Mgodi, Luis Gadama, Moleen Matrimbira, Catherine Anne Chappell, Jeanna Pi...> ;Journal of Acquired Immune Deficiency Syndromes. 2023 Sep 27
3 citations
Hepatitis C Virus in Pregnancy: An Opportunity to Test and Treat.
Rachel S Fogel, Catherine A Chappell> ;Obstetrics and Gynecology Clinics of North America. 2023 Jun 1
Effect of double-dose levonorgestrel subdermal implant in women taking efavirenz-based antiretroviral therapy: The DoubLNG pharmacokinetic study.
Lauren R Cirrincione, Shadia Nakalema, Catherine A Chappell, Pauline Byakika-Kibwika, Isabella Kyohairwe, Lee Winchester, Hope Mackline, Michelle M Pham, Susan E Cohn,...> ;Contraception. 2023 Jun 1
1 citations
Evidence for Implementation: HIV/HCV Coinfection and Pregnancy.
Megan Rose Curtis, Catherine Chappell> ;Current HIV/AIDS Reports. 2023 Feb 1
Dextromethorphan as a novel nonopioid adjunctive agent for pain control with medication abortion: A randomized controlled trial.
Grace P Ferguson, Sharon L Achilles, Leslie A Meyn, Colleen M Krajewski, Catherine A Chappell, Kavita Vinekar, Beatrice A Chen> ;Contraception. 2023 Feb 1
2 citations
Pharmacokinetics of levonorgestrel and etonogestrel contraceptive implants over 48 weeks with rilpivirine- or darunavir-based antiretroviral therapy.
Shadia Nakalema, Catherine A Chappell, Michelle Pham, Pauline Byakika-Kibwika, Julian Kaboggoza, Stephen I Walimbwa, Joseph Musaazi, Ritah Nakijoba, Leah Mbabazi, Isab...> ;The Journal of Antimicrobial Chemotherapy. 2022 Oct 28
1 citations
Letter to the Editor: Pregnant Women and their Providers Want Direct-Acting Antivirals, and We Are Missing the Mark.
Tatyana Kushner, Catherina A. Chappell> ;Hepatology. 2021 Oct 1
7 citations
Experiences and Perspectives From Women Taking Investigational Therapy for Hepatitis C Virus During Pregnancy.
Yasaswi Kislovskiy, Catherine A. Chappell, Emily Flaherty, Megan Hamm, Elizabeth E. Krans, Judy C. Chang> ;Substance Abuse. 2021 Sep 28
3 citations
Hepatitis C Virus in Pregnancy: Are We Ready for Test and Treat?
Catherine A. Chappell, Maureen M. Jonas> ;The Journal of Infectious Diseases. 2020 Nov 27
56 citations
Ledipasvir plus sofosbuvir in pregnant women with hepatitis C virus infection: a phase 1 pharmacokinetic study
Catherine A. Chappell, Kimberly K. Scarsi, Brian J. Kirby, Vithika Suri, Anuj Gaggar, Debra L. Bogen, Ingrid Macio, Leslie A. Meyn, Katherine E. Bunge, Elizabeth E. Kr...> ;The Lancet. Microbe. 2020 Sep 1
18 citations
Elevated Risk of Bacterial Vaginosis Among Users of the Copper Intrauterine Device: A Prospective Longitudinal Cohort Study.
Kathryn Peebles, Flavia Matovu Kiweewa, Thesla Palanee-Phillips, Catherine A. Chappell, Devika Singh, Katherine E. Bunge, Logashvari Naidoo, Bonus Makanani, Nitesha Je...> ;Clinical Infectious Diseases. 2021 Aug 2
5 citations
Feasibility and Safety of IUD Insertion by Mid-Level Providers in Sub-Saharan Africa.
Felix Mhlanga, Jennifer E. Balkus, Devika Singh, Catherine A. Chappell, Betty Kamira, Ishana Harkoo, Daniel W. Szydlo, Shorai Mukaka, Jeanna M. Piper, Sharon L. Hillier> ;International Perspectives on Sexual and Reproductive Health. 2019 Dec 17
9 citations
Effect of patient genetics on etonogestrel pharmacokinetics when combined with efavirenz or nevirapine ART.
Megan Neary, Catherine A. Chappell, Kimberly K. Scarsi, Shadia Nakalema, Joshua Matovu, Sharon L. Achilles, Beatrice A. Chen, Marco Siccardi, Andrew Owen, Mohammed Lam...> ;The Journal of Antimicrobial Chemotherapy. 2019 Oct 1
Drug interactions: not just for orally administered drugs.
Catherine A. Chappell, Sharon L. Achilles> ;The Lancet. HIV. 2019 Sep 1
7 citations
Contraceptive method switching among women living in sub-Saharan Africa participating in an HIV-1 prevention trial: a prospective cohort study
Catherine A. Chappell, Ishana Harkoo, Daniel W. Szydlo, Katherine E. Bunge, Clemensia Nakabiito, Felix Mhlanga, Betty Kamira, Jeanna M. Piper, Jennifer E. Balkus, Shar...> ;Contraception. 2019 Sep 1
6 citations
Testing for Hepatitis C in Pregnancy: the Time has Come for Routine Rather than Risk-based.
Tatyana Kushner, Catherine A. Chappell, Arthur Y. Kim> ;Current Hepatology Reports. 2019 May 9
69 citations
Hepatitis C Virus Screening Among Children Exposed During Pregnancy
Catherine A. Chappell, Sharon L. Hillier, David Crowe, Leslie A. Meyn, Debra L. Bogen, Elizabeth E. Krans> ;Pediatrics. 2018 Jun 1
3 citations
Heterogeneity of HIV-1 Replication in Ectocervical and Vaginal Tissue Ex Vivo.
Charlene S. Dezzutti, Seo Young Park, Kenneth M Marks, Sidney E Lawlor, Julie Russo, Ingrid Macio, Catherine A. Chappell, Katherine E. Bunge> ;AIDS Research and Human Retroviruses. 2017 Dec 14
11 citations
Brief Report: Dapivirine Vaginal Ring Use Does Not Diminish the Effectiveness of Hormonal Contraception.
Jennifer E. Balkus, Thesla Palanee-Phillips, Krishnaveni Reddy, Samantha Siva, Ishana Harkoo, Clemensia Nakabiito, Kenneth Kintu, Gonasangrie Nair, Catherine A. Chappe...> ;Journal of Acquired Immune Deficiency Syndromes. 2017 Oct 1
34 citations
Efavirenz decreases etonogestrel exposure: a pharmacokinetic evaluation of implantable contraception with antiretroviral therapy
Catherine A. Chappell, Mohammed Lamorde, Shadia Nakalema, Beatrice A. Chen, Hope Mackline, Sharon A. Riddler, Susan E. Cohn, Kristin M. Darin, Sharon L. Achilles, Kimb...> ;AIDS. 2017 Sep 10
Use of an endotracheal tube for surgical abortion complicated by a leiomyomatous uterus: a case report.
Christy M. Boraas, Catherine A. Chappell, Colleen M. Krajewski> ;Journal of Medical Case Reports. 2017 Aug 25
14 citations
Synthetic osmotic dilators with adjunctive misoprostol for same-day dilation and evacuation: a randomized controlled trial
Christy M. Boraas, Sharon L. Achilles, Miriam Cremer, Catherine A. Chappell, Sarah E. Lim, Beatrice A. Chen> ;Contraception. 2016 Nov 1
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Press Mentions

Hepatitis C Widespread but Rarely Treated in Postpartum Medicaid Beneficiaries with Opioid Use DisorderApril 7th, 2022
Virtual Conference croi2022 HighlightsMarch 22nd, 2022
Trial Finds Drug Safe and Effective in Treating Hep-C During PregnancyJuly 28th, 2020
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