CatherineJDattoMD

Geriatrics • Wilmington, DE

Medical Lead, US Medical Affairs, AstraZeneca Pharmaceuticals LP

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Office
1800 Concord Pike
Wilmington, DE 19850
Phone+1 302-885-1948
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Education & Training

Rutgers Robert Wood Johnson Medical SchoolClass of 1994

Certifications & Licensure

PA State Medical License 1996 - 2014

Clinical Trials

Phase 3 /Seroquel SR Acute Mania Monotherapy - US Start of enrollment: 2007 Jan 01
Completed
Phase 3
Phase III/Seroquel SR Bipolar Depression Monotherapy - US Start of enrollment: 2006 Dec 01
Completed
Phase 3
Quetiapine Fumarate Immediate Release (IR) Versus Extended Release (XR) Dose Escalation Comparison Start of enrollment: 2008 Jul 01
Completed
Phase 1
A Study Assessing Inhibition of Serum Thromboxane B2 Levels With PN400 and Low Dose Aspirin Start of enrollment: 2010 Mar 01
Completed
Phase 1
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Publications & Presentations

PubMed

10 citations
A Randomized, Multicenter, Prospective, Crossover, Open-Label Study of Factors Associated With Patient Preferences for Naloxegol or PEG 3350 for Opioid-Induced Constip...
Darren M. Brenner, Yiqun Hu, Catherine Datto, Dana Creanga, Michael Camilleri> ;The American Journal of Gastroenterology. 2019 Jun 1
11 citations
Analysis of Patient-Provider Interactions Regarding the Burden and Treatment of Opioid-Induced Constipation in Adults with Chronic Noncancer Pain.
April Hazard Vallerand, Sarah Hendry, Elizabeth Baldys, Yiqun Hu, Catherine Datto> ;Pain Medicine. 2019 May 1
13 citations
Impact of opioid-induced constipation on healthcare resource utilization and costs for cancer pain patients receiving continuous opioid therapy
Perry G. Fine, Yen-Wen Chen, Eric Wittbrodt, Catherine Datto> ;Supportive Care in Cancer. 2019 Feb 1
Efficacy and safety of naloxegol for opioid-induced constipation assessed by specific opioid medication, opioid dose, and duration of opioid use.
Nalamachu, S.,Gudin, J.,Datto, C.,Coyne, K.,Poon, J. L.,Hu, Y.> ;J Opioid Manag. 2018 Jul 26
8 citations
The Burden of Opioid-Induced Constipation in Younger Patients with Chronic Noncancer Pain.
Anita Gupta, Karin S. Coyne, Catherine Datto, Christine Venuti> ;Pain Medicine. 2018 Dec 1
9 citations
Translating Clinical Findings into the Patient's Perspective: Post-hoc Pooled Analysis of Bowel Movement Changes as a Predictor of Improvement in Patients' Opioid-indu...
Karin S. Coyne, Jiat-Ling Poon, Christine Thompson, Yiqun Hu, Catherine Datto, Mark Sostek> ;Clinical Therapeutics. 2017 Jan 1
6 citations
Laxative utilization over time in chronic pain patients with opioid-induced constipation.
Catherine Datto, Robert J. LoCasale, Mary Kay Margolis, Christine L. Thompson, Karin S. Coyne> ;Pain Management. 2016 Aug 1
16 citations
Corrigendum to “Effectiveness of the Extended Release Formulation of Quetiapine as Monotherapy for the Treatment of Acute Bipolar Depression” [J. Affect. Disord. 121 (...
Trisha Suppes, Catherine Datto, Margaret Minkwitz, Arvid Nordenhem, Chris Walker, Denis Darko> ;Journal of Affective Disorders. 2014 Oct 15
15 citations
Impact of concomitant low-dose aspirin on the safety and tolerability of naproxen and esomeprazole magnesium delayed-release tablets in patients requiring chronic nons...
Dominick J. Angiolillo, Catherine Datto, Shane Raines, Neville D. Yeomans> ;Journal of Thrombosis and Thrombolysis. 2014 Jul 1
83 citations
Opioid-induced constipation in patients with chronic noncancer pain in the USA, Canada, Germany, and the UK: descriptive analysis of baseline patient-reported outcomes...
Karin S. Coyne, Robert J. LoCasale, Catherine Datto, Chris C. Sexton, Karen Yeomans, Jan Tack> ;Clinicoeconomics and Outcomes Research. 2014 May 23
9 citations
Effects of once-daily extended release quetiapine fumarate (quetiapine XR) on quality of life and sleep in elderly patients with major depressive disorder.
Julie C. Locklear, Henrik Svedsater, Catherine Datto, Jean Endicott> ;Journal of Affective Disorders. 2013 Jul 1
5 citations
Quetiapine XR monotherapy in major depressive disorder: a pooled analysis to assess the influence of baseline severity on efficacy.
Michael E. Thase, Stuart Montgomery, George I. Papakostas, Michael Bauer, Madhukar H. Trivedi, Henrik Svedsater, Julie C. Locklear, Urban Gustafsson, Catherine Datto, ...> ;International Clinical Psychopharmacology. 2013 May 1
13 citations
Impact of a Fixed-Dose Combination of Naproxen and Esomeprazole Magnesium on Serum Thromboxane B2 Inhibition by Low-Dose Aspirin Over 5 Days in Healthy Adults: A Phase...
Dominick J. Angiolillo, Clara Hwang, Catherine Datto, Bhaloo Desai, Mark Sostek> ;Clinical Therapeutics. 2011 Dec 1
35 citations
Extended-Release Quetiapine as Monotherapy for the Treatment of Adults With Acute Mania: A Randomized, Double-Blind, 3-Week Trial
Andrew J. Cutler, Catherine Datto, Arvid Nordenhem, Margaret Minkwitz, Larisa D. Acevedo, Denis Darko> ;Clinical Therapeutics. 2011 Nov 1
65 citations
Efficacy and tolerability of extended release quetiapine fumarate (quetiapine XR) monotherapy in major depressive disorder: a placebo-controlled, randomized study.
Brian Bortnick, Nizar El-Khalili, Michael Banov, David E. Adson, Catherine Datto, Shane Raines, Willie Earley, Hans Eriksson> ;Journal of Affective Disorders. 2011 Jan 1
61 citations
A pooled analysis of two randomised, placebo-controlled studies of extended release quetiapine fumarate adjunctive to antidepressant therapy in patients with major dep...
Michael Bauer, Nizar El-Khalili, Catherine Datto, Johan Szamosi, Hans Eriksson> ;Journal of Affective Disorders. 2010 Dec 1
72 citations
Efficacy and Tolerability of Extended Release Quetiapine Fumarate Monotherapy as Maintenance Treatment of Major Depressive Disorder: A Randomized, Placebo-Controlled T...
Michael Liebowitz, Raymond W. Lam, Ulla Lepola M.D., Catherine Datto, Dennis Sweitzer, M.B.A. Hans Eriksson M.D.> ;Depression and Anxiety. 2010 Oct 1
136 citations
Extended-release quetiapine fumarate (quetiapine XR) as adjunctive therapy in major depressive disorder (MDD) in patients with an inadequate response to ongoing antide...
Nizar El-Khalili, Mark Joyce, Sarah Atkinson, Robert Buynak, Catherine Datto, Petter Lindgren, Hans Eriksson> ;The International Journal of Neuropsychopharmacology. 2010 Aug 1
47 citations
Self-reported sedation profile of immediate-release quetiapine fumarate compared with extended-release quetiapine fumarate during dose initiation: a randomized, double...
Catherine Datto, Lovisa Berggren, Jitendra B. Patel, Hans Eriksson> ;Clinical Therapeutics. 2009 Mar 1
23 citations
Clinical manifestations, diagnosis, and empirical treatments for catatonia.
Mahendra T. Bhati, Catherine J. Datto, John P. O'Reardon> ;Psychiatry. 2007 Mar 1
13 citations
Propofol for the management of emergence agitation after electroconvulsive therapy: review of a case series.
John P. O'Reardon, Nadia Takieddine, Catherine J. Datto, John G.T. Augoustides> ;The Journal of ECT. 2006 Dec 1
Cognitive behavior therapy and clozapine synergy in an older adult with schizophrenia
Narsimha R. Pinninti, Catherine J. Datto> ;The American Journal of Geriatric Psychiatry. 2006 Aug 1
182 citations
Outcomes of minor and subsyndromal depression among elderly patients in primary care settings.
Jeffrey M. Lyness, Moonseong Heo, Catherine J. Datto, Thomas R. Ten Have, Ira R. Katz, Rebecca A. Drayer, Charles F. Reynolds, George S. Alexopoulos, Martha L. Bruce> ;Annals of Internal Medicine. 2006 Apr 4
9 citations
Older adult report of change in depressive symptoms as a treatment decision tool.
Catherine J. Datto, Richard Thompson, Kathryn Knott, Ira R. Katz> ;Journal of the American Geriatrics Society. 2006 Apr 1
15 citations
A Daily Diary Study of Late-Life Depression
Lara G. Chepenik, Thomas R. Ten Have, David W. Oslin, Catherine J. Datto, Cynthia Zubritsky, Ira R. Katz> ;The American Journal of Geriatric Psychiatry. 2006 Mar 1
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Journal Articles

Analysis of Patient–Provider Interactions Regarding the Burden and Treatment of Opioid-Induced Constipation in Adults with Chronic Noncancer Pain
Catherine Datto, MD, Pain Medicine

Press Mentions

Opioid Utilization Patterns Among Patients with Cancer and Non-Cancer PainMarch 12th, 2019