CatherineMO'ConnellMD

PubMed

• 17 citations
  Anti‐chlamydia IgG and IgA are insufficient to prevent endometrial chlamydia infection in women, and increased anti‐chlamydia IgG is associated with enhanced risk for ...
  Toni Darville, Hannah L. Albritton, Wujuan Zhong, Li Dong, Catherine M. O'Connell, Taylor B. Poston, Alison J. Quayle, Nilu Goonetilleke, Harold C. Wiesenfeld, Sharon ...> ;American Journal of Reproductive Immunology. 2019 May 1
• 6 citations
  Simultaneous profiling of sexually transmitted bacterial pathogens, microbiome, and concordant host response in cervical samples using whole transcriptome sequencing a...
  Catherine M. O'Connell, Hayden N. Brochu, Jenna Girardi, Erin Harrell, Aiden Jones, Toni Darville, Arlene C. Seña, Xinxia Peng> ;Microbial Cell. 2019 Jan 24
• 15 citations
  Gene Expression Signatures Can Aid Diagnosis of Sexually Transmitted Infection-Induced Endometritis in Women.
  Xiaojing Zheng, Catherine M. O'Connell, Wujuan Zhong, Taylor B. Poston, Harold C. Wiesenfeld, Sharon L. Hillier, Maria Trent, Charlotte A. Gaydos, George C. Tseng, Bra...> ;Frontiers in Cellular and Infection Microbiology. 2018 Sep 20
• 12 citations
  Discovery of Human-Specific Immunodominant Chlamydia trachomatis B Cell Epitopes.
  K. Shamsur Rahman, Toni Darville, Ali N. Russell, Catherine M. O'Connell, Harold C. Wiesenfeld, Sharon L. Hillier, Erfan U. Chowdhury, Yen-Chen Juan, Bernhard Kaltenboeck> ;Msphere. 2018 Aug 1
• 14 citations
  Comprehensive molecular serology of human Chlamydia trachomatis infections by peptide enzyme-linked immunosorbent assays.
  K. Shamsur Rahman, Toni Darville, Ali N. Russell, Catherine M. O'Connell, Harold C. Wiesenfeld, Sharon L. Hillier, De’Ashia E. Lee, Bernhard Kaltenboeck> ;Msphere. 2018 Aug 1
• 14 citations
  T Cell-Independent Gamma Interferon and B Cells Cooperate To Prevent Mortality Associated with Disseminated Chlamydia muridarum Genital Tract Infection.
  Taylor B. Poston, Catherine M. O'Connell, Jenna Girardi, Jeanne E. Sullivan, Uma M. Nagarajan, Anthony D. Marinov, Amy M. Scurlock, Toni Darville> ;Infection and Immunity. 2018 Jun 21
• 14 citations
  Risk factors for Mycoplasma genitalium endometritis and incident infection: a secondary data analysis of the T cell Response Against Chlamydia (TRAC) Study
  Brandie D. Taylor, Xiaojing Zheng, Catherine M. O'Connell, Harold C. Wiesenfeld, Sharon L. Hillier, Toni Darville> ;Sexually Transmitted Infections. 2018 Mar 21
• 14 citations
  Discovery of Blood Transcriptional Endotypes in Women with Pelvic Inflammatory Disease.
  Xiaojing Zheng, Catherine M. O'Connell, Wujuan Zhong, Uma M. Nagarajan, Manoj K. Tripathy, De’Ashia Lee, Ali N. Russell, Harold C. Wiesenfeld, Sharon Hillier, Toni Dar...> ;Journal of Immunology. 2018 Mar 12
• 17 citations
  A Chlamydia -Specific TCR-Transgenic Mouse Demonstrates Th1 Polyfunctionality with Enhanced Effector Function.
  Taylor B. Poston, Yanyan Qu, Jenna Girardi, Catherine M. O'Connell, Lauren C. Frazer, Ali N. Russell, McKensie Wall, Uma M. Nagarajan, Toni Darville> ;Journal of Immunology. 2017 Aug 30
• 11 citations
  Whole-Exome Sequencing to Identify Novel Biological Pathways Associated With Infertility After Pelvic Inflammatory Disease.
  Brandie D. Taylor, Xiaojing Zheng, Toni Darville, Wujuan Zhong, Kranti Konganti, Olayinka Abiodun-Ojo, Roberta B. Ness, Catherine M. O'Connell, Catherine L. Haggerty> ;Sexually Transmitted Diseases. 2017 Jan 1
• 31 citations
  Comparable genital tract infection, pathology, and immunity in rhesus macaques inoculated with wild-type or plasmid-deficient Chlamydia trachomatis serovar D
  Yanyan Qu, Lauren C. Frazer, Catherine M. O'Connell, Alice F. Tarantal, Charles W. Andrews, Shelby L. O’Connor, Ali N. Russell, Jeanne E. Sullivan, Taylor B. Poston, A...> ;Infection and Immunity. 2015 Oct 1
• 41 citations
  Analysis of Factors Driving Incident and Ascending Infection and the Role of Serum Antibody in Chlamydia trachomatis Genital Tract Infection
  Ali N. Russell, Xiaojing Zheng, Catherine M. O'Connell, Brandie D. Taylor, Harold C. Wiesenfeld, Sharon L. Hillier, Wujuan Zhong, Toni Darville> ;The Journal of Infectious Diseases. 2016 Feb 15
• 3 citations
  Steroids alone or as adjunctive therapy with doxycycline fail to improve oviduct damage in mice infected with Chlamydia muridarum.
  Tammy E. Corr, Jeanne E. Sullivan, Lauren C. Frazer, Charles W. Andrews, Catherine M. O'Connell, Toni Darville> ;Clinical and Vaccine Immunology. 2014 Jun 1
• 23 citations
  Frequency of Chlamydia trachomatis-specific T cell interferon-γ and interleukin-17 responses in CD4-enriched peripheral blood mononuclear cells of sexually active adol...
  Romina Barral, Ruchi Desai, Xiaojing Zheng, Lauren C. Frazer, Gina S. Sucato, Catherine L. Haggerty, Catherine M. O'Connell, Matthew A. Zurenski, Toni Darville> ;Journal of Reproductive Immunology. 2014 Jun 1
• 32 citations
  Oral Administration of the Pimelic Diphenylamide HDAC Inhibitor HDACi 4b Is Unsuitable for Chronic Inhibition of HDAC Activity in the CNS In Vivo
  Maria Beconi, Omar Aziz, Kim L. Matthews, Lara Moumné, Catherine M. O'Connell, Dawn Yates, Steven Clifton, Hannah Pett, Julie Vann, Lynsey Crowley, Alan Findlay Haugha...> ;Plos One. 2012 Sep 4
• 24 citations
  The recall response induced by genital challenge with Chlamydia muridarum protects the oviduct from pathology but not from reinfection.
  Melissa M. Riley, Matthew A. Zurenski, Lauren C. Frazer, Catherine M. O'Connell, Charles W. Andrews, Margaret Mintus, Toni Darville> ;Infection and Immunity. 2012 Jun 1
• 26 citations
  Plasmid-Cured Chlamydia caviae Activates TLR2-Dependent Signaling and Retains Virulence in the Guinea Pig Model of Genital Tract Infection
  Lauren C. Frazer, Toni Darville, Kumar Chandra-Kuntal, Charles W. Andrews, Matthew A. Zurenski, Margaret Mintus, Yasser M. AbdelRahman, Robert J. Belland, Robin R. Ing...> ;Plos One. 2012 Jan 24
• 42 citations
  Enhanced neutrophil longevity and recruitment contribute to the severity of oviduct pathology during Chlamydia muridarum infection.
  Lauren C. Frazer, Catherine M. O'Connell, Charles W. Andrews, Matthew A. Zurenski, Toni Darville> ;Infection and Immunity. 2011 Oct 1
• 16 citations
  Enhanced virulence of Chlamydia muridarum respiratory infections in the absence of TLR2 activation.
  Xianbao He, Anjali Nair, Samrawit Mekasha, Joseph Alroy, Catherine M. O'Connell, Robin R. Ingalls> ;Plos One. 2011 Jun 14
• 88 citations
  Interleukin-17 Contributes to Generation of Th1 Immunity and Neutrophil Recruitment during Chlamydia muridarum Genital Tract Infection but Is Not Required for Macropha...
  Amy M. Scurlock, Lauren C. Frazer, Charles W. Andrews, Catherine M. O'Connell, Isaac P. Foote, Sarabeth L. Bailey, Kumar Chandra-Kuntal, Jay K. Kolls, Toni Darville> ;Infection and Immunity. 2011 Mar 1
• 28 citations
  Chlamydial Infection Increases Gonococcal Colonization in a Novel Murine Coinfection Model
  Rachel A. Vonck, Toni Darville, Catherine M. O'Connell, Ann E. Jerse> ;Infection and Immunity. 2011 Apr 1
• 79 citations
  Toll-Like Receptor 2 Activation by Chlamydia trachomatis Is Plasmid Dependent, and Plasmid-Responsive Chromosomal Loci Are Coordinately Regulated in Response to Glucos...
  Catherine M. O'Connell, Yasser M. AbdelRahman, Erin R. Green, Hillary K. Darville, Kazima Saira, Bennett Smith, Toni Darville, Amy M. Scurlock, Christopher R Meyer, Ro...> ;Infection and Immunity. 2011 Mar 1
• 41 citations
  Infectivity acts as in vivo selection for maintenance of the chlamydial cryptic plasmid
  Marsha Y. Russell, Toni Darville, Kumar Chandra-Kuntal, Bennett Smith, Charles W. Andrews, Catherine M. O'Connell> ;Infection and Immunity. 2011 Jan 1
• 163 citations
  Plasmid-Deficient Chlamydia muridarum Fail to Induce Immune Pathology and Protect against Oviduct Disease
  Catherine M. O'Connell, Robin R. Ingalls, Charles W. Andrews, Amy M. Scurlock, Toni Darville> ;Journal of Immunology. 2007 Sep 15
• 1 citations
  Lack of an Effect of Antibiotic Treatment on Prolonged Detection of Chlamydial DNA in Murine Genital Tract Infection
  Dawn M. Reeves, Uma M. Nagarajan, Catherine M. O'Connell, Charles W. Andrews, Toni Darville> ;Antimicrobial Agents and Chemotherapy. 2007 Jul 1
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