CatherineSearsMD

Pulmonology • Indianapolis, IN

Critical Care Medicine, Thoracic Oncology

Associate Professor, Medicine, Indiana University School of Medicine

Join to view full profile

Dr. Sears is on Doximity

As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.

Connect with other colleagues in the same hospital or clinic
Search all U.S. specialist profiles and refer a patient
Read the latest clinical news and earn CME/CEU credits

See Dr. Sears' full profile

Already have an account?

Office
Walther Hall, 900 W. Walnut
C400
Indianapolis, IN 46202
Phone+1 317-948-2894

Fax+1 317-988-3976
Is this information wrong?

Education & Training

Indiana University School of MedicineFellowship, Pulmonary Disease and Critical Care Medicine, 2008 - 2011
Vanderbilt University Medical CenterResidency, Internal Medicine, 2005 - 2008
Indiana University School of MedicineClass of 2005

Certifications & Licensure

IN State Medical License 2008 - 2025
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Clinical Trials

Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy Start of enrollment: 2017 Apr 13
Recruiting
Not Applicable
Nodify XL2 Classifier Clinical Utility Study in Low to Moderate Risk Lung Nodules Start of enrollment: 2020 Dec 18
Recruiting

Publications & Presentations

PubMed

XPC Protects against Carcinogen-Induced Histologic Progression to Lung Squamous Cell Carcinoma by Reduced Basal Epithelial Cell Proliferation.
Huaxin Zhou, Emily Hulsey, Bea A Aidoo, George E Sandusky, Nawar Al Nasrallah, Catherine R Sears> ;Cancers. 2024 Apr 13
Racial disparities in staging, treatment, and mortality in non-small cell lung cancer.
Al Nasrallah, N., Han, Y., Killion, A., Liu, H., Duncan, F., Nephew, L., Al-Hader, A., Sears, C.> ;Translational Lung Cancer Research. 2024 Jan 31
Lung Cancer Screening: Millions of Promises and More Challenges.
Robert Smyth, Catherine R Sears> ;Chest. 2023 Jul 1
10 citations
Mouse pulmonary interstitial macrophages mediate the pro-tumorigenic effects of IL-9.
Yongyao Fu, Abigail Pajulas, Jocelyn Wang, Baohua Zhou, Anthony Cannon, Cherry Cheuk Lam Cheung, Jilu Zhang, Huaxin Zhou, Amanda Jo Fisher, David T Omstead, Sabrina Kh...> ;Nature Communications. 2022 Jul 1
DNA Repair Capacity for Personalizing Risk and Treatment Response - Assay Development and Optimization in Human Peripheral Blood Mononuclear Cells (PBMCs).
Nawar Al Nasrallah, Huaxin Zhou, Patricia A Smith, Catherine R Sears> ;DNA Repair. 2022 Mar 1
7 citations
Xeroderma Pigmentosum Complementation Group C (XPC): Emerging Roles in Non-Dermatologic Malignancies.
Nawar Al Nasrallah, Benjamin M Wiese, Catherine R Sears, Al Nasrallah, N.> ;Frontiers in Oncology. 2022 Jan 1
Low-Coverage Whole Genome Sequencing Using Laser Capture Microscopy with Combined Digital Droplet PCR: An Effective Tool to Study Copy Number and Kras Mutations in Ear...
Elizabeth A. Mickler, Huaxin Zhou, Tzu L. Phang, Mark W. Geraci, Robert S Stearman, Catherine R. Sears> ;International Journal of Molecular Sciences. 2021 Nov 6
3 citations
Age, Sex, Smoking, and Race: Is Progress Being Made in Lung Cancer Screening Eligibility?
Catherine R. Sears, M. Patricia Rivera> ;Chest. 2021 Jul 1
1 citations
Hemophagocytic Lymphohistiocytosis in the Medical ICU: A Single-Institution Cohort Study on Acute Liver Failure and Mortality.
Nawar Al Nasrallah, Ahmad Al-Hader, Niharika Samala, Catherine R. Sears> ;Critical Care Explorations. 2021 Jan 1
15 citations
Discovery and development of novel DNA-PK inhibitors by targeting the unique Ku-DNA interaction.
Navnath Gavande, Pamela S. VanderVere-Carozza, Katherine S. Pawelczak, Pamela Mendoza-Munoz, Tyler L. Vernon, Leslyn A. Hanakahi, Matthew Summerlin, Joseph R. Dynlacht...> ;Nucleic Acids Research. 2020 Nov 18
Patient Perspectives on Shared Decision-Making in Lung Cancer Screening: To Teach or To Trust?
Francesca Duncan, Catherine R. Sears> ;Chest. 2020 Sep 1
13 citations
Mortality Rates in a Diverse Cohort of Mechanically Ventilated Patients With Novel Coronavirus in the Urban Midwest
Homer L. Twigg, Sikandar H. Khan, Anthony J. Perkins, Scott D. Roberts, Catherine R. Sears, Omar Rahman, Joseph Smith, Rajat Kapoor, Mark O. Farber, Timothy J. Ellende...> ;Critical Care Explorations. 2020 Aug 20
31 citations
Biomarkers in Lung Cancer.
Catherine R. Sears, Peter J. Mazzone> ;Clinics in Chest Medicine. 2020 Jan 2
1 citations
Safely and Effectively Evaluating Computed Tomography–detected Lung Lesions. Much Work to Be Done
A. Cole Burks, Michael K. Gould, Gerard A. Silvestri, Lonny Yarmus, Catherine R. Sears, Douglas A. Arenberg, Anne V. Gonzalez, Christopher G. Slatore, Nichole T. Tanne...> ;Annals of the American Thoracic Society. 2019 Nov 1
79 citations
Knowledge Gaps and Research Priorities in Immune Checkpoint Inhibitor–related Pneumonitis An Official American Thoracic Society Research Statement
Catherine R. Sears, Tobias Peikert, Jennifer D. Possick, Jarushka Naidoo, Mizuki Nishino, Sandip Pravin Patel, Philippe Camus, Mina Gaga, Edward B. Garon, Michael K. G...> ;American Journal of Respiratory and Critical Care Medicine. 2019 Sep 15
10 citations
XPC protects against smoking- and carcinogen-induced lung adenocarcinoma.
Huaxin Zhou, Jacob Saliba, George E. Sandusky, Catherine R. Sears> ;Carcinogenesis. 2019 May 14
17 citations
DNA repair as an emerging target for COPD-lung cancer overlap.
Catherine R. Sears> ;Respiratory Investigation. 2019 Jan 7
3 citations
Biomarkers in Pulmonary Nodule Diagnosis: Is It Time to Put Away the Biopsy Needle?
Nawar Al Nasrallah, Catherine R. Sears> ;Chest. 2018 Sep 1
16 citations
Xeroderma Pigmentosum Group C Deficiency Alters Cigarette Smoke DNA Damage Cell Fate and Accelerates Emphysema Development
Catherine R. Sears, Huaxin Zhou, Matthew J. Justice, Amanda J. Fisher, Jacob Saliba, Isaac Lamb, Jessica Wicker, Kelly S. Schweitzer, Irina Petrache> ;American Journal of Respiratory Cell and Molecular Biology. 2017 Nov 7
68 citations
Evaluating Molecular Biomarkers for the Early Detection of Lung Cancer: When Is a Biomarker Ready for Clinical Use? An Official American Thoracic Society Policy Statement
Peter J. Mazzone, Catherine R. Sears, Doug A. Arenberg, Mina Gaga, Michael K. Gould, Pierre P. Massion, Vish S. Nair, Charles A. Powell, Gerard A. Silvestri, Anil Vach...> ;American Journal of Respiratory and Critical Care Medicine. 2017 Sep 29
7 citations
Multicenter Validation of a Customizable Scoring Tool for Selection of Trainees for a Residency or Fellowship Program. The EAST-IST Study.
Gabriel T. Bosslet, W. Graham Carlos, David J. Tybor, Jennifer W. McCallister, Candace Huebert, Ashley G. Henderson, Matthew C. Miles, Homer L. Twigg, Catherine R. Sea...> ;Annals of the American Thoracic Society. 2017 Mar 31
36 citations
DNA damage response (DDR) pathway engagement in cisplatin radiosensitization of non-small cell lung cancer.
Catherine R. Sears, Sean A. Cooney, Helen Chin-Sinex, Marc S. Mendonca, John J. Turchi> ;DNA Repair. 2016 Apr 1
247 citations
DNA repair targeted therapy: The past or future of cancer treatment?
Navnath Gavande, Pamela S. VanderVere-Carozza, Hilary D. Hinshaw, Shadia I. Jalal, Catherine R. Sears, Katherine S. Pawelczak, John J. Turchi> ;Pharmacology & Therapeutics. 2016 Apr 1
15 citations
Recognition of DNA Termini by the C-Terminal Region of the Ku80 and the DNA-Dependent Protein Kinase Catalytic Subunit.
Derek S. Woods, Catherine R. Sears, John J. Turchi> ;Plos One. 2015 May 15
40 citations
Complex Cisplatin-double strand break (DSB) lesions directly impair cellular non-homologous end-joining (NHEJ) independent of downstream damage response (DDR) pathways
Catherine R. Sears, John J. Turchi> ;The Journal of Biological Chemistry. 2012 Jul 13
Join now to see all

Press Mentions

bioAffinity Technologies Announces Dr. Martin Tammemägi to Chair Scientific and Medical Advisory BoardSeptember 29th, 2020
Lung Cancer Screenings to Expand for Indiana Veterans Thanks to $1 Million GrantDecember 21st, 2023

Hospital Affiliations

Richard L. Roudebush Veterans Affairs Medical CenterIndianapolis, Indiana
Eskenazi HealthIndianapolis, Indiana
Indiana University Health University HospitalIndianapolis, Indiana
Indiana University Health North HospitalCarmel, Indiana
Indiana University Health West HospitalAvon, Indiana