ChadAGrotegutMDMBA

Obstetrics & Gynecology

Maternal & Fetal Medicine/High Risk

Maternal-Fetal Medicine, Wake Forest University School of Medicine

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Education & Training

Duke UniversityMBA, Business Administration, 2017 - 2018
Duke UniversityMHS, Clinical Research, 2009 - 2012
Duke University HospitalFellowship, Maternal-Fetal Medicine, 2006 - 2009
Duke University HospitalResidency, Obstetrics and Gynecology, 1999 - 2003
Lewis Katz School of Medicine at Temple UniversityClass of 1999
University of VirginiaBS, Chemical Engineering, 1990 - 1994

Certifications & Licensure

NC State Medical License 2000 - 2024
PA State Medical License 2003 - 2008
DE State Medical License 2003 - 2004
American Board of Obstetrics and Gynecology Obstetrics & Gynecology
American Board of Obstetrics and Gynecology Maternal-Fetal Medicine

Clinical Trials

Foley Bulb With Low Dose Pitocin Versus Foley Bulb With a Standard Incremental Infusion Protocol for the Induction of Labor Start of enrollment: 2007 Dec 01
Completed
Phase 4
Collection of Samples From Pregnant Women for the Evaluation of Preeclampsia (Pre-E) Biomarkers Start of enrollment: 2016 Jan 01
Completed
NT-proBNP Levels and Obesity in Pregnancy Start of enrollment: 2019 Jul 15
Completed
The Collection and Application of Autologous Amniotic Fluid at Cesarean Delivery Closure. Start of enrollment: 2020 Oct 01
Active, not recruiting
Not Applicable
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Publications & Presentations

PubMed

Evaluating the Association Between Fibrinogen and Rotational Thromboelastometry and the Progression to Severe Obstetric Hemorrhage.
Mary Yurashevich, Morgan Rosser, Maria Small, Chad Grotegut, Nancy Kota, John Toffaletti, Terrence Allen> ;Clinical and Applied Thrombosis/hemostasis. 2023 May 15
3 citations
Pregnancy-Associated Extracorporeal Membrane Oxygenation in the United States.
Megan S Varvoutis, Lauren E Wein, Ronan Sugrue, Kristin C Darwin, Arthur J Vaught, Marie-Louise Meng, Brenna L Hughes, Chad A Grotegut, Jerome J Federspiel> ;American Journal of Perinatology. 2023 Feb 15
3 citations
Obstructive Sleep Apnea Among Gravidas With Chronic Hypertension Compared to Matched Controls: A Prospective Cohort Study.
Jennifer E Dominguez, Chad A Grotegut, Mary Cooter Wright, Ashraf S Habib> ;Anesthesia and Analgesia. 2023 Feb 1
1 citations
Prospective Observational Study of N-terminal Pro-Brain Natriuretic Peptide Levels in Obese and Nonobese Women during Pregnancy.
Anna E Denoble, Julia M Moyett, Sarah A Goldstein, Cary C Ward, Tracy Truong, Alaattin Erkanli, Andra H James, Chad A Grotegut> ;American Journal of Perinatology. 2023 Apr 1
Impact of Pre-Existing Ischemic Heart Disease on Severe Maternal Morbidity and Mortality During Delivery Hospitalizations.
Anna E Denoble, Sarah A Goldstein, Lauren E Wein, Chad A Grotegut, Jerome J Federspiel> ;JACC. Advances. 2022 Dec 1
4 citations
Risk of obstetric anal sphincter injuries at the time of admission for delivery: A clinical prediction model.
Douglas Luchristt, Ana Rebecca Meekins, Congwen Zhao, Chad Grotegut, Nazema Y Siddiqui, Brooke Alhanti, John Eric Jelovsek> ;BJOG. 2022 Nov 1
3 citations
Transfusion Requirements with Hybrid Management of Placenta Accreta Spectrum Incorporating Targeted Embolization and a Selective Use of Delayed Hysterectomy.
Luke A Gatta, Jeremy M Weber, Jennifer B Gilner, Paula S Lee, Chad A Grotegut, Katherine A Herbert, Mustafa Bashir, Carl F Pieper, James Ronald, Waleska Pabon-Ramos, A...> ;American Journal of Perinatology. 2022 Oct 1
1 citations
Comparison of severe maternal morbidity in pregnancy by modified World Health Organization Classification of maternal cardiovascular risk.
Anna E Denoble, Sarah A Goldstein, Lauren E Wein, Chad A Grotegut, Jerome J Federspiel> ;American Heart Journal. 2022 Aug 1
Performance of a Multianalyte 'Rule-Out' Assay in Pregnant Individuals With Suspected Preeclampsia.
Maged M Costantine, Baha Sibai, Allan T Bombard, Mark Sarno, Holly West, David M Haas, Alan T Tita, Michael J Paidas, Erin A S Clark, Kim Boggess, Chad Grotegut, Willi...> ;Hypertension. 2022 Jul 1
Anesthetic management of placenta accreta spectrum at an academic center and a comparison of the combined spinal epidural with the double catheter technique: A retrosp...
Katherine A Herbert, Luke A Gatta, Matthew Fuller, Chad A Grotegut, Jennifer Gilner, Ashraf S Habib> ;Journal of Clinical Anesthesia. 2022 May 1
1 citations
The Hassan Neonatal Morbidity Composite Scale and Neonatal Length of Stay-A Validation Study.
Avinash S. Patil, Chad A. Grotegut, P. Brian Smith, Reese H. Clark, Rachel G. Greenberg> ;American Journal of Perinatology. 2021 Dec 2
1 citations
Universal SARS-CoV-2 testing for obstetric inpatient units across the United States.
Jennifer Gilner, Namita Kansal, Joseph R. Biggio, Shani Delaney, Chad A. Grotegut, Erica J. Hardy, Adi Hirshberg, Alisa Kachikis, Sylvia M LaCourse, Jane Martin, Torri...> ;Clinical Infectious Diseases. 2021 Nov 17
2 citations
Severe Congenital Syphilis in the Neonatal Intensive Care Unit: A Retrospective Case Series.
Samia Aleem, LaShawndra S. Walker, Chi D. Hornik, Michael J. Smith, Chad A. Grotegut, Kristin E. D. Weimer> ;The Pediatric Infectious Disease Journal. 2021 Oct 5
4 citations
Placental uterine artery embolization followed by delayed hysterectomy for placenta percreta: A case series.
Luke A. Gatta, Paula S. Lee, Jennifer Gilner, Jeremy M. Weber, LaMani Adkins, Julia R. Salinaro, Ashraf S. Habib, Waleska M. Pabon-Ramos, Kyle C. Strickland, James Ron...> ;Gynecologic Oncology Reports. 2021 Jul 16
2 citations
Prediction of neonatal morbidity and very preterm delivery using maternal steroid biomarkers in early gestation.
Avinash S. Patil, Chad A. Grotegut, Nilesh W. Gaikwad, Shelley D. Dowden, David M. Haas> ;Plos One. 2021 Jan 6
13 citations
Endocannabinoid System in Pregnancy Maintenance and Labor: A Mini-Review.
Melissa L. Kozakiewicz, Chad A. Grotegut, Allyn C. Howlett> ;Frontiers in Endocrinology. 2021 Jan 1
2 citations
Spontaneous Broad Ligament Hematoma after Vaginal Delivery Requiring Hysterectomy
Megan Varvoutis, Nguyen Thao Thi Nguyen, Chad A. Grotegut> ;AJP Reports. 2021 Jan 1
20 citations
Transcriptome and regulatory maps of decidua-derived stromal cells inform gene discovery in preterm birth.
Noboru J. Sakabe, Ivy Aneas, Nicholas W. Knoblauch, Débora R. Sobreira, Nicole Clark, Cristina Paz, Cynthia Horth, Ryan Ziffra, Harjot Kaur, Xiao Liu, Rebecca Anderson...> ;Science Advances. 2020 Dec 2
11 citations
Prospective, randomized, double-blind, placebo-controlled evaluation of the Pharmacokinetics, Safety and Efficacy of Recombinant Antithrombin Versus Placebo in Preterm...
Michael J. Paidas, Allan T.N. Tita, George A. Macones, George A. Saade, Richard A. Ehrenkranz, Elizabeth W. Triche, James B. Streisand, Garrett K. Lam, Everett F. Maga...> ;American Journal of Obstetrics and Gynecology. 2020 Nov 1
6 citations
How do I develop a process to effectively treat parturients with iron deficiency anemia
Nicole R. Guinn, Mary Cooter, Yasmin Maisonave, Aime Grimsley, Cindy Cellura, Chad A. Grotegut, Agnes M Lamon, Solomon Aronson, Duke Perioperative Enhancement Team> ;Transfusion. 2020 Jul 13
20 citations
A national update on rates of postpartum haemorrhage and related interventions.
Homa K. Ahmadzia, Chad A. Grotegut, Andra H. James> ;Blood Transfusion = Trasfusione Del Sangue. 2020 May 15
4 citations
Can a Structured, Electronic Approach to Shared Decision-making Increase Attempted Trial of Labor?
Geeta K. Swamy, Chad A. Grotegut> ;JAMA. 2020 Jun 2
16 citations
The β-arrestin-biased β-adrenergic receptor blocker carvedilol enhances skeletal muscle contractility
Jihee Kim, Chad A. Grotegut, James W. Wisler, Lan Mao, Paul B. Rosenberg, Howard A. Rockman, Robert J. Lefkowitz> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 May 15
1 citations
Analgesic use after vaginal delivery in women with perineal lacerations: a retrospective cohort study.
Nicole N Hawkins, Agnes M Lamon, Yi-Ju Li, Chad A. Grotegut, Ashraf S. Habib> ;Current Medical Research and Opinion. 2020 Apr 22
5 citations
Alterations in endogenous progesterone metabolism associated with spontaneous very preterm delivery
Avinash S. Patil, Nilesh W. Gaikwad, Chad A. Grotegut, Shelley D. Dowden, David M. Haas> ;Human Reproduction Open. 2020 Feb 1
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Journal Articles

1171 Steroidogenic Enzyme Activity Is Predictive of Spontaneous Preterm Delivery
Chad Grotegut, Ravindu Gunatilake, American Journal of Obstetrics and Gynecology
Prospective Randomized Double-Blind, Placebo Controlled Evaluation of the Pharmacokinetics, Safety and Efficacy of Recombinant Antithrombin Versus Placebo in Preterm P...
Michael J Paidas, George A Macones, Garrett K Lam, Everett F Magann, Erika F Werner, Mounira A Habli, Chad A Grotegut, Sherri A Longo, Erol Amon, William A Grobman, De..., American Journal of Obstetrics and Gynecology

Authored Content

Prospective Randomized Double-Blind, Placebo Controlled Evaluation of the Pharmacokinetics, Safety and Efficacy of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia (PRESERVE-1)August 2020

Professional Memberships

American College of Obstetricians and Gynecologists
Fellow

Hospital Affiliations

Atrium Wake Forest BaptistWinston Salem, North Carolina
Catawba Valley Medical CenterHickory, North Carolina