ChanheeHanMD

PubMed

• The Poly (ADP-ribose) polymerase inhibitor olaparib and pan-ErbB inhibitor neratinib are highly synergistic in HER2 overexpressing epithelial ovarian carcinoma in vitr...
  Chanhee Han, Blair McNamara, Stefania Bellone, Justin Harold, Paola Manara, Tobias Max Philipp Hartwich, Levent Mutlu, Yang Yang-Hartwich, Margherita Zipponi, Cem Demi...> ;Gynecologic Oncology. 2023 Mar 1
• 1 citations
  Incidence and predictors of toxicity in the management of vulvar squamous cell carcinoma treated with radiation therapy.
  Neal S McCall, Tony Y Eng, Joseph W Shelton, Sheela Hanasoge, Pretesh R Patel, Ashish B Patel Jr, Ashley A McCook-Veal, Jeffrey M Switchenko, Tonya E Cole, Namita Khan...> ;Gynecologic Oncology Reports. 2022 Dec 1
• 9 citations
  Prescribed medical cannabis in women with gynecologic malignancies: A single-institution survey-based study.
  Emily Webster, Ghanshyam Yadav, Stefan Gysler, Blair McNamara, Jonathan Black, Joan Tymon-Rosario, Burak Zeybek, Chanhee Han, Christopher Ke Arkfeld, Vaagn Andikyan, G...> ;Gynecologic Oncology Reports. 2020 Nov 2
• 2 citations
  Derangements in HUWE1/c-MYC pathway confer sensitivity to the BET bromodomain inhibitor GS-626510 in uterine cervical carcinoma.
  Elena Bonazzoli, Stefania Bellone, Luca Zammataro, Barbara Gnutti, Adele Guglielmi, Silvia Pelligra, Nupur Nagarkatti, Paola Manara, Joan Tymon-Rosario, Burak Zeybek, ...> ;Gynecologic Oncology. 2020 Jun 26
• 17 citations
  Sacituzumab govitecan, an antibody-drug conjugate targeting trophoblast cell-surface antigen 2, shows cytotoxic activity against poorly differentiated endometrial aden...
  Emanuele Perrone, Paola Manara, Salvatore Lopez, Stefania Bellone, Elena Bonazzoli, Aranzazu Manzano, Luca Zammataro, Anna Bianchi, Burak Zeybek, Natalia Buza, Joan Ty...> ;Molecular Oncology. 2020 Mar 1
• 26 citations
  Preclinical Activity of Sacituzumab Govitecan, an Antibody-Drug Conjugate Targeting Trophoblast Cell-Surface Antigen 2 (Trop-2) Linked to the Active Metabolite of Irin...
  Emanuele Perrone, Salvatore Lopez, Burak Zeybek, Stefania Bellone, Elena Bonazzoli, Silvia Pelligra, Luca Zammataro, Aranzazu Manzano, Paola Manara, Anna Bianchi, Nata...> ;Frontiers in Oncology. 2020 Feb 12
• 26 citations
  Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas.
  Salvatore Lopez, Emanuele Perrone, Stefania Bellone, Elena Bonazzoli, Burak Zeybek, Chanhee Han, Joan Tymon-Rosario, Gary Altwerger, Gulden Menderes, Anna Bianchi, Luc...> ;Oncotarget. 2020 Feb 4
• 15 citations
  In vitro and in vivo activity of sacituzumab govitecan, an antibody-drug conjugate targeting trophoblast cell-surface antigen 2 (Trop-2) in uterine serous carcinoma.
  Chanhee Han, Emanuele Perrone, Burak Zeybek, Stefania Bellone, Joan Tymon-Rosario, Gary Altwerger, Gulden Menderes, Jacqueline Feinberg, Kaitlin Haines, Mariana Espina...> ;Gynecologic Oncology. 2020 Feb 1
• 22 citations
  Cervical carcinomas that overexpress human trophoblast cell-surface marker (Trop-2) are highly sensitive to the antibody-drug conjugate sacituzumab govitecan.
  Burak Zeybek, Aranzazu Manzano, Anna Bianchi, Elena Bonazzoli, Stefania Bellone, Natalia Buza, Pei Hui, Salvatore Lopez, Emanuele Perrone, Paola Manara, Luca Zammataro...> ;Scientific Reports. 2020 Jan 22
• 46 citations
  Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy.
  Luca Zammataro, Salvatore Lopez, Stefania Bellone, Francesca Pettinella, Elena Bonazzoli, Emanuele Perrone, Siming Zhao, Gulden Menderes, Gary Altwerger, Chanhee Han, ...> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Nov 5
• Synergistic clinical efficacy of niraparib in combination with pembrolizumab in patients with recurrent platinum-resistant ovarian carcinoma.
  Joan Tymon-Rosario, Burak Zeybek, Chanhee Han, Alessandro D. Santin> ;Annals of Translational Medicine. 2019 Dec 1
• 22 citations
  PARP-1 activity (PAR) determines the sensitivity of cervical cancer to olaparib
  Anna Bianchi, Salvatore Lopez, Gary Altwerger, Stefania Bellone, Elena Bonazzoli, Luca Zammataro, Aranzazu Manzano, Paola Manara, Emanuele Perrone, Burak Zeybek, Chanh...> ;Gynecologic Oncology. 2019 Oct 1
• 11 citations
  PI3K oncogenic mutations mediate resistance to afatinib in HER2/neu overexpressing gynecological cancers.
  Elena Bonazzoli, Emiliano Cocco, Salvatore Lopez, Stefania Bellone, Luca Zammataro, Anna Bianchi, Aranzazu Manzano, Ghanshyam Yadav, Paola Manara, Emanuele Perrone, Ka...> ;Gynecologic Oncology. 2019 Apr 1
• 41 citations
  Mutational landscape of primary, metastatic, and recurrent ovarian cancer reveals c-MYC gains as potential target for BET inhibitors.
  Charles Li, Elena Bonazzoli, Stefania Bellone, Jungmin Choi, Weilai Dong, Gulden Menderes, Gary Altwerger, Chanhee Han, Aranzazu Manzano, Anna Bianchi, Francesca Petti...> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Jan 8
• 1 citations
  Correction: Mutational landscape of primary, metastatic, and recurrent ovarian cancer reveals c-MYC gains as potential target for BET inhibitors (Proceedings of the Na...
  Charles Li, Elena Bonazzoli, Stefania Bellone, Jungmin Choi, Weilai Dong, Gulden Menderes, Gary Altwerger, Chanhee Han, Aranzazu Manzano, Anna Bianchi, Francesca Petti...> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Jan 1
• 13 citations
  Inhibition of BET Bromodomain Proteins with GS-5829 and GS-626510 in Uterine Serous Carcinoma, a Biologically Aggressive Variant of Endometrial Cancer
  Elena Bonazzoli, Federica Predolini, Emiliano Cocco, Stefania Bellone, Gary Altwerger, Gulden Menderes, Luca Zammataro, Anna Bianchi, Francesca Pettinella, Francesco R...> ;Clinical Cancer Research. 2018 Oct 1
• 21 citations
  Mechanisms of resistance to HER2-targeted therapies in HER2-amplified uterine serous carcinoma, and strategies to overcome it.
  Gulden Menderes, Salvatore Lopez, Chanhee Han, Gary Altwerger, Stepan Gysler, Joyce Varughese, Peter E. Schwartz, Alessandro D. Santin> ;Discovery Medicine. 2018 Aug 1
• 16 citations
  Novel targeted therapies in ovarian and uterine carcinosarcomas.
  Chanhee Han, Gary Altwerger, Gulden Menderes, Kaitlin Haines, Jacqueline Feinberg, Salvatore Lopez, Aranzazu Manzano, Joyce Varughese, Alessandro D. Santin> ;Discovery Medicine. 2018 Jun 1
• 42 citations
  A novel multiple biomarker panel for the early detection of high-grade serous ovarian carcinoma.
  Chanhee Han, Stefania Bellone, Eric R. Siegel, Gary Altwerger, Gulden Menderes, Elena Bonazzoli, Tomomi Egawa-Takata, Francesca Pettinella, Anna Bianchi, Francesco Ric...> ;Gynecologic Oncology. 2018 Jun 1
• 15 citations
  Binimetinib (MEK162) in recurrent low-grade serous ovarian cancer resistant to chemotherapy and hormonal treatment.
  Chanhee Han, Stefania Bellone, Luca Zammataro, Peter E. Schwartz, Alessandro D. Santin> ;Gynecologic Oncology Reports. 2018 May 24
• 10 citations
  Sacituzumab Govitecan (IMMU-132) in treatment-resistant uterine serous carcinoma: A case report.
  Chanhee Han, Stefania Bellone, Peter E. Schwartz, Serengulam V. Govindan, Robert M. Sharkey, David M. Goldenberg, Alessandro D. Santin> ;Gynecologic Oncology Reports. 2018 May 23
• 18 citations
  In Vitro and In Vivo Activity of IMGN853, an Antibody–Drug Conjugate Targeting Folate Receptor Alpha Linked to DM4, in Biologically Aggressive Endometrial Cancers
  Gary Altwerger, Elena Bonazzoli, Stefania Bellone, Tomomi Egawa-Takata, Gulden Menderes, Francesca Pettinella, Anna Bianchi, Francesco Riccio, Jacqueline Feinberg, Luc...> ;Molecular Cancer Therapeutics. 2018 May 1
• 3 citations
  Construct Validity of a Simple Laparoscopic Ovarian Cystectomy Model Using a Validated Objective Structured Assessment of Technical Skills
  Elizabeth Britton Chahine, Chan Hee Han, Tamika C. Auguste> ;Journal of Minimally Invasive Gynecology. 2017 Jul 1
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