ChaoLuDO MD FAAPMR

PubMed

• 1 citations
  Patient-derived three-dimensional culture techniques model tumor heterogeneity in head and neck cancer.
  Anuraag S Parikh, Victoria X Yu, Samuel Flashner, Ogoegbunam B Okolo, Chao Lu, Brian S Henick, Fatemeh Momen-Heravi, Sidharth V Puram, Theodoros Teknos, Quintin Pan, H...> ;Oral Oncology. 2023 Mar 1
• 6 citations
  SOX9 Modulates the Transformation of Gastric Stem Cells Through Biased Symmetric Cell Division.
  Qiyue Chen, Kai Weng, Mi Lin, Ming Jiang, Yinshan Fang, Sanny S W Chung, Xiaobo Huang, Qing Zhong, Zhiyu Liu, Zening Huang, Jianxian Lin, Ping Li, Wael El-Rifai, Alexa...> ;Gastroenterology. 2023 Jun 1
• 4 citations
  Reliable and Accurate Prediction of Single-Residue pValues through Free Energy Perturbation Calculations.
  Dilek Coskun, Wei Chen, Anthony J Clark, Chao Lu, Edward D Harder, Lingle Wang, Richard A Friesner, Edward B Miller> ;Journal of Chemical Theory and Computation. 2022 Dec 13
• 14 citations
  Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas.
  Yinglu Li, Elizabeth M Goldberg, Xiao Chen, Xinjing Xu, John T McGuire, Giuseppe Leuzzi, Dimitris Karagiannis, Tiffany Tate, Nargess Farhangdoost, Cynthia Horth, Esthe...> ;Molecular Cell. 2022 Oct 20
• 46 citations
  Dissecting the treatment-naive ecosystem of human melanoma brain metastasis.
  Jana Biermann, Johannes C Melms, Amit Dipak Amin, Yiping Wang, Lindsay A Caprio, Alcida Karz, Somnath Tagore, Irving Barrera, Miguel A Ibarra-Arellano, Massimo Andreat...> ;Cell. 2022 Jul 7
• 11 citations
  H3K36 dimethylation shapes the epigenetic interaction landscape by directing repressive chromatin modifications in embryonic stem cells.
  Haifen Chen, Bo Hu, Cynthia Horth, Eric Bareke, Phillip Rosenbaum, Sin Young Kwon, Jacinthe Sirois, Daniel N Weinberg, Faith M Robison, Benjamin A Garcia, Chao Lu, Wil...> ;Genome Research. 2022 May 1
• 5 citations
  Oncohistones: Hijacking the histone code.
  Varun Sahu, Chao Lu> ;Annual Review of Cancer Biology. 2022 Apr 1
• 5 citations
  The cAMP signaling pathway regulates Epe1 protein levels and heterochromatin assembly.
  Kehan Bao, Chun-Min Shan, Xiao Chen, Gulzhan Raiymbek, Jeremy G Monroe, Yimeng Fang, Takenori Toda, Kristin S Koutmou, Kaushik Ragunathan, Chao Lu, Luke E Berchowitz, ...> ;Plos Genetics. 2022 Feb 1
• 12 citations
  CHAF1A/B mediate silencing of unintegrated HIV-1 DNAs early in infection.
  Franziska K Geis, Yosef Sabo, Xiao Chen, Yinglu Li, Chao Lu, Stephen P Goff> ;Proceedings of the National Academy of Sciences of the United States of America. 2022 Jan 25
• 20 citations
  Histone H3.3 K27M and K36M mutations de-repress transposable elements through perturbation of antagonistic chromatin marks.
  Amel Chaouch, Johannes Berlandi, Carol C.L. Chen, Felice Frey, Shireen Badini, Ashot S. Harutyunyan, Xiao Chen, Brian Krug, Steven Hébert, Astrid Jeibmann, Chao Lu, Cl...> ;Molecular Cell. 2021 Nov 4
• 19 citations
  Nanostructure Engineering of Graphitic Carbon Nitride for Electrochemical Applications.
  Chao Lu, Xi Chen> ;ACS Nano. 2021 Nov 1
• 25 citations
  Pparg signaling controls bladder cancer subtype and immune exclusion.
  Tiffany A. Tate, Tina Xiang, Sarah E. Wobker, Mi Zhou, Xiao Chen, Hyunwoo Kim, Ekatherina Batourina, Chyuan-Sheng Lin, William Y. Kim, Chao Lu, James M. McKiernan, Cat...> ;Nature Communications. 2021 Oct 25
• 21 citations
  Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.
  Pooja Panwalkar, Benita Tamrazi, Derek Dang, Chan Chung, Stefan Sweha, Siva Kumar Natarajan, Matthew Pun, Jill Bayliss, Martin P. Ogrodzinski, Drew Pratt, Brendan Mull...> ;Science Translational Medicine. 2021 Oct 6
• 3 citations
  Growth Inhibition and Induction of Innate Immune Signaling of Chondrosarcomas with Epigenetic Inhibitors
  Tahir N. Sheikh, Xiao Chen, Xinjing Xu, John T. McGuire, Matthew Ingham, Chao Lu, Gary K. Schwartz> ;Molecular Cancer Therapeutics. 2021 Sep 22
• 4 citations
  Highly Sensitive Ultrastable Electrochemical Sensor Enabled by Proton-Coupled Electron Transfer.
  Chao Lu, Xiangbiao Liao, Daining Fang, Xi Chen> ;Nano Letters. 2021 Jun 14
• 441 citations
  OPLS4: Improving Force Field Accuracy on Challenging Regimes of Chemical Space.
  Chao Lu, Chuanjie Wu, Delaram Ghoreishi, Wei Chen, Lingle Wang, Wolfgang Damm, Gregory A. Ross, Markus K. Dahlgren, Ellery Russell, Christopher D Von Bargen, Robert Ab...> ;Journal of Chemical Theory and Computation. 2021 Jun 7
• 7 citations
  The histone H3K9M mutation synergizes with H3K14 ubiquitylation to selectively sequester histone H3K9 methyltransferase Clr4 at heterochromatin.
  Chun-Min Shan, Jin-Kwang Kim, Jiyong Wang, Kehan Bao, Yadong Sun, Huijie Chen, Jia-Xing Yue, Alessandro Stirpe, Zhiguo Zhang, Chao Lu, Thomas Schalch, Gianni Liti, Pet...> ;Cell Reports. 2021 May 18
• 45 citations
  Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands.
  Daniel N. Weinberg, Phillip Rosenbaum, Xiao Chen, Douglas Barrows, Cynthia Horth, Matthew R. Marunde, Irina K. Popova, Zachary B. Gillespie, Michael-Christopher Keogh,...> ;Nature Genetics. 2021 May 13
• 71 citations
  The interplay between DNA and histone methylation: molecular mechanisms and disease implications.
  Yinglu Li, Xiao Chen, Chao Lu> ;EMBO Reports. 2021 May 5
• 26 citations
  Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation
  Kartik N. Rajagopalan, Xiao Chen, Daniel N. Weinberg, Haifen Chen, Jacek Majewski, C. David Allis, Chao Lu> ;Proceedings of the National Academy of Sciences of the United States of America. 2021 Mar 2
• 34 citations
  Chromatin dysregulation associated with NSD1 mutation in head and neck squamous cell carcinoma
  Nargess Farhangdoost, Cynthia Horth, Bo Hu, Eric Bareke, Xiao Chen, Yinglu Li, Mariel Coradin, Benjamin A. Garcia, Chao Lu, Jacek Majewski> ;Cell Reports. 2021 Feb 23
• 114 citations
  Functional interrogation of DNA damage response variants with base editing screens
  Raquel Cuella-Martin, Samuel B. Hayward, Xiao Fan, Xiao Chen, Jen-Wei Huang, Angelo Taglialatela, Giuseppe Leuzzi, Junfei Zhao, Raul Rabadan, Chao Lu, Yufeng Shen, Alb...> ;Cell. 2021 Feb 18
• 1 citations
  Decoding the function of an oncogenic transcription factor: finding the first responders.
  Chao Lu> ;Molecular Cell. 2021 Feb 4
• 16 citations
  The INO80 Complex Regulates Epigenetic Inheritance of Heterochromatin.
  Chun-Min Shan, Kehan Bao, Jolene K. Diedrich, Xiao Chen, Chao Lu, John R. Yates, Songtao Jia> ;Cell Reports. 2020 Dec 29
• 4 citations
  Chromosome 3p loss of heterozygosity and reduced expression of H3K36me3 correlate with longer relapse-free survival in sacral conventional chordoma
  Guo Gord Zhu, Daniel Ramirez, Wen Chen, Chao Lu, Lu Wang, Denise Frosina, Achim A. Jungbluth, Peter Ntiamoah, Khedoudja Nafa, Patrick J. Boland, Meera Hameed> ;Human Pathology. 2020 Aug 12
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