CharlesMichaelCottenMD

Neonat/Perinatology • Durham, NC

Professor of Pediatrics, Duke University School of Medicine

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Office
2400 Pratt Street
8th floor
Durham, NC 27710
Phone+1 919-681-6035
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Education & Training

Duke UniversityMasters, Health Sciences, 2001 - 2006
Tufts Medical CenterFellowship, Neonatal-Perinatal Medicine, 1989 - 1993
University of Miami/Jackson Health SystemResidency, Pediatrics, 1987 - 1989
University of Miami Leonard M. Miller School of MedicineClass of 1986

Certifications & Licensure

NC State Medical License 1996 - 2024
MA State Medical License 1992 - 2005
FL State Medical License 1988 - 1998
American Board of Pediatrics Neonatal-Perinatal Medicine

Clinical Trials

Cord Blood for Neonatal Hypoxic-ischemic Encephalopathy Start of enrollment: 2008 Jan 01
Completed
Phase 1
Safety and Feasibility Study of Umbilical Cord Blood Cells for Infants With Hypoplastic Left Heart Syndrome Start of enrollment: 2011 Sep 01
Terminated
Phase 1
Gastrin-Releasing Peptide and Bronchopulmonary Dysplasia Start of enrollment: 2012 May 01
Completed
Analyzing Retinal Microanatomy in ROP Start of enrollment: 2016 Jul 22
Completed
Retinal Microanatomy in Retinopathy of Prematurity (BabySTEPS2) Start of enrollment: 2021 Aug 16
Recruiting
Not Applicable
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Publications & Presentations

PubMed

5 citations
A Pilot Phase I Trial of Allogeneic Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells in Neonates With Hypoxic-Ischemic Encephalopathy.
Charles Michael Cotten, Kimberley Fisher, William Malcolm, Kathryn E Gustafson, Lynn Cheatham, Amanda Marion, Rachel Greenberg, Joanne Kurtzberg> ;Stem Cells Translational Medicine. 2023 Jun 15
3 citations
Contributions of the NICHD neonatal research network to the diagnosis, prevention, and treatment of bronchopulmonary dysplasia.
Erik A Jensen, Matthew M Laughon, Sara B DeMauro, C Michael Cotten, Barbara Do, Waldemar A Carlo, Kristi L Watterberg> ;Seminars in Perinatology. 2022 Nov 1
Indomethacin Prophylaxis in Preterm Infants: Changes over Time.
Samantha F Curtis, C Michael Cotten, Matthew Laughon, Noelle Younge, Jennifer Peterson, Reese H Clark, Rachel G Greenberg> ;American Journal of Perinatology. 2022 Sep 29
1 citations
Indomethacin Prophylaxis in Preterm Infants: Changes over Time.
Samantha F Curtis, C Michael Cotten, Matthew Laughon, Noelle Younge, Jennifer Peterson, Reese H Clark, Rachel G Greenberg> ;American Journal of Perinatology. 2022 Oct 19
Outcomes of Moderately Preterm Infants of Insulin-Dependent Diabetic Mothers.
Keyaria D Gray, Shampa Saha, Ashley N Battarbee, Charles Michael Cotten, Nansi S Boghossian, Michele C Walsh, Rachel G Greenberg> ;American Journal of Perinatology. 2022 May 27
3 citations
Blanket temperature during therapeutic hypothermia and outcomes in hypoxic ischemic encephalopathy.
John Flibotte, Abbot R Laptook, Seetha Shankaran, Scott A McDonald, Mariana C Baserga, Edward F Bell, C Michael Cotten, Abhik Das, Sara B DeMauro, Tara L DuPont, Eric ...> ;Journal of Perinatology. 2022 Mar 1
44 citations
Initial Laparotomy Versus Peritoneal Drainage in Extremely Low Birthweight Infants With Surgical Necrotizing Enterocolitis or Isolated Intestinal Perforation: A Multic...
Martin L. Blakely, Jon E. Tyson, Kevin P. Lally, Susan R. Hintz, Barry Eggleston, David K. Stevenson, Gail E. Besner, Abhik Das, Robin K. Ohls, William E Truog, Leif D...> ;Annals of Surgery. 2021 Oct 1
6 citations
Associations between systemic health and retinal nerve fibre layer thickness in preterm infants at 36 weeks postmenstrual age.
Liangbo L Shen, Shwetha Mangalesh, Suzanne M. Michalak, Brendan McGeehan, Neeru Sarin, Joanne Finkle, Katrina P. Winter, Du Tran-Viet, Eric J. Benner, Lejla Vajzovic, ...> ;The British Journal of Ophthalmology. 2021 Aug 13
Which infants should receive indomethacin prophylaxis: moving closer to individualized medicine in the neonatal intensive care unit.
Samantha Curtis, Noelle Younge, Jennifer Peterson, C. Michael Cotten, Samia Aleem, Rachel G. Greenberg> ;The Journal of Pediatrics. 2021 Jul 9
2 citations
Growth Rates of Infants Randomized to Continuous Positive Airway Pressure or Intubation After Extremely Preterm Birth.
Ariel A. Salas, Waldemar A. Carlo, Barbara Do, Edward F. Bell, Abhik Das, Krisa P. Van Meurs, Brenda B. Poindexter, Seetha Shankaran, Noelle Younge, Kristi L. Watterbe...> ;The Journal of Pediatrics. 2021 Jun 19
21 citations
Therapies for neonatal encephalopathy: Targeting the latent, secondary and tertiary phases of evolving brain injury.
Aravanan Anbu Chakkarapani, Hany Aly, Manon J.N.L. Benders, C. Michael Cotten, Mohamed El-Dib, Pierre Gressens, Henrik Hagberg, Hemmen Sabir, Pia Wintermark, Nicola J....> ;Seminars in Fetal & Neonatal Medicine. 2021 Jun 12
5 citations
Antibiotic Safety and Effectiveness in Premature Infants With Complicated Intraabdominal Infections.
Michael J. Smith, Angelique E Boutzoukas, Julie Autmizguine, Mark L. Hudak, Erin K. Zinkhan, Barry T. Bloom, Gloria P Heresi, Adrian Lavery, Sherry E. Courtney, Gregor...> ;The Pediatric Infectious Disease Journal. 2021 Jun 1
10 citations
Early Determination of Prognosis in Neonatal Moderate or Severe Hypoxic-Ischemic Encephalopathy
Namasivayam Ambalavanan, Seetha Shankaran, Abbot R. Laptook, Benjamin Carper, Abhik Das, Waldemar A. Carlo, C. Michael Cotten, Andrea F Duncan, Rosemary D. Higgins> ;Pediatrics. 2021 May 13
17 citations
Preterm Infant Stress During Handheld Optical Coherence Tomography vs Binocular Indirect Ophthalmoscopy Examination for Retinopathy of Prematurity.
Shwetha Mangalesh, Neeru Sarin, Brendan McGeehan, S. Grace Prakalapakorn, Du Tran-Viet, C. Michael Cotten, Sharon F. Freedman, Maureen G. Maguire, Cynthia A. Toth> ;JAMA Ophthalmology. 2021 May 1
2 citations
Neurodevelopmental outcome of preterm infants enrolled in myo-inositol randomized controlled trial
Ira Adams-Chapman, Kristi L. Watterberg, Tracy L. Nolen, Shawn Hirsch, Carol A. Cole, C. Michael Cotten, William Oh, Brenda B. Poindexter, Kristin M. Zaterka-Baxter, A...> ;Journal of Perinatology. 2021 Mar 23
1 citations
Genetic predictors of severe intraventricular hemorrhage in extremely low-birthweight infants.
Courtney D. Thornburg, Stephen W. Erickson, Grier P. Page, Erin A.S. Clark, Margaret M. DeAngelis, M Elizabeth Hartnett, Ricki F. Goldstein, John M. Dagle, Jeffrey C. ...> ;Journal of Perinatology. 2021 Jan 31
Correction: Genetic predictors of severe intraventricular hemorrhage in extremely low-birthweight infants.
Courtney D. Thornburg, Stephen W. Erickson, Grier P. Page, Erin A.S. Clark, Margaret M. DeAngelis, M Elizabeth Hartnett, Ricki F. Goldstein, John M. Dagle, Jeffrey C. ...> ;Journal of Perinatology. 2021 Jan 31
6 citations
Blood myo-inositol concentrations in preterm and term infants
Ivan D. Frantz, Luc P. Brion, Dale L. Phelps, Robert M. Ward, Tracy L. Nolen, N. Mikko K. Hallman, Abhik Das, Daniel J. Zaccaro, M. Bethany Ball, Kristi L. Watterberg,...> ;Journal of Perinatology. 2021 Jan 31
24 citations
Neurodevelopmental outcomes following neonatal late-onset sepsis and blood culture-negative conditions
Sagori Mukhopadhyay, Karen M. Puopolo, Nellie I. Hansen, Scott A. Lorch, Sara B. DeMauro, Rachel G. Greenberg, C. Michael Cotten, Pablo J. Sánchez, Edward F. Bell, Eri...> ;Archives of Disease in Childhood. Fetal and Neonatal Edition. 2021 Jan 21
17 citations
Umbilical Cord Milking vs Delayed Cord Clamping and Associations with In-Hospital Outcomes among Extremely Premature Infants.
Neha Kumbhat, Barry Eggleston, Alexis S. Davis, Sara B. DeMauro, Krisa P. Van Meurs, Elizabeth E. Foglia, Satyan Lakshminrusimha, Michele C. Walsh, Kristi L. Watterber...> ;The Journal of Pediatrics. 2021 Jan 5
13 citations
Perspectives from the Society for Pediatric Research. Neonatal encephalopathy clinical trials: developing the future.
Kristen L Benninger, Terrie E. Inder, Amy M. Goodman, C. Michael Cotten, Douglas R. Nordli, Tushar A. Shah, James C. Slaughter, Nathalie L. Maitre> ;Pediatric Research. 2021 Jan 1
96 citations
Higher or Lower Hemoglobin Transfusion Thresholds for Preterm Infants
Haresh Kirpalani, Edward F. Bell, Susan R. Hintz, Sylvia Tan, Barbara Schmidt, Aasma S. Chaudhary, Karen J. Johnson, Margaret M. Crawford, Jamie E. Newman, Betty R. Vo...> ;The New England Journal of Medicine. 2020 Dec 30
9 citations
Withholding or withdrawing life-sustaining treatment in extremely low gestational age neonates
April R. Dworetz, Girija Natarajan, John C. Langer, Kathy Kinlaw, Jennifer R James, Margarita Bidegain, Abhik Das, Brenda B. Poindexter, Edward F. Bell, C M Cotten, Ha...> ;Archives of Disease in Childhood. Fetal and Neonatal Edition. 2021 May 1
6 citations
Infection control and other stewardship strategies in late onset sepsis, necrotizing enterocolitis, and localized infection in the neonatal intensive care unit.
Samia Aleem, Megan Wohlfarth, C. Michael Cotten, Rachel G. Greenberg> ;Seminars in Perinatology. 2020 Oct 12
Association between neonatal intensive care unit medication safety practices, adverse events, and death
Laura E Miller, Chris DeRienzo, P. Brian Smith, Carl L. Bose, Reese H. Clark, C. Michael Cotten, Daniel K. Benjamin, Chi D. Hornik, Rachel G. Greenberg> ;Journal of Perinatology. 2021 Jul 1
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