CharlesMichaelKnudsonMD

Pathology • Iowa City, IA

Blood Banking & Transfusion Medicine, Clinical Pathology

Associate Professor, Pathology, University of Iowa Roy J. and Lucille A. Carver COM

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Office
200 Hawkins Dr
Iowa City, IA 52242
Phone+1 319-335-8147

Fax+1 319-335-8453
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Summary

Dr. Charles Knudson is a pathologist in Iowa City, IA and is affiliated with multiple hospitals in the area, including Iowa City VA Health Care System and University of Iowa Hospitals and Clinics. He received his medical degree from University of Iowa Roy J. and Lucille A. Carver College of Medicine and has been in practice 25 years. He specializes in blood banking & transfusion medicine and clinical pathology.

Education & Training

Washington University/B-JH/SLCH ConsortiumResidency, Pathology-Anatomic and Clinical, 1992 - 1998
University of Iowa Roy J. and Lucille A. Carver College of MedicineClass of 1992

Certifications & Licensure

IA State Medical License 1998 - 2025
American Board of Pathology Clinical Pathology

Clinical Trials

Biorepository and Registry for Plasma Exchange Patients Start of enrollment: 2021 Jul 28
Recruiting
Roles: Contact, Sponsor-Investigator

Publications & Presentations

PubMed

Using the daily rate of rise in hemoglobin S to manage RBC depletion/exchange treatment in sickle cell disease.
Kai Rogers, James Chapman, Mouaz Alsawas, Annette J Schlueter, Charles Michael Knudson> ;Transfusion. 2024 Apr 1
1 citations
Comparison of platelet antibody screen, crossmatching and HLA antibody testing in patients refractory to platelet transfusions.
James M Chapman, Linder Wendt, C Michael Knudson> ;Transfusion and Apheresis Science. 2023 Jun 1
1 citations
In response to Joubeh and Singh: Allergic reactions to platelets; to B or not to B?
Siera Rossi, Linder Wendt, Zuhair Ballas, C Michael Knudson> ;Transfusion. 2022 Dec 1
Patient ABO blood type is a major predictor of a positive DAT following a transfusion reaction.
Eric Schnieders, Judith Leon, James M Chapman, C Michael Knudson> ;Transfusion. 2022 Sep 1
1 citations
Hemolytic disease of the fetus and newborn in the sensitizing pregnancy where anti-D was incorrectly identified as RhIG.
Mackenzie L Walhof, Judith Leon, James R Scott, Charles Michael Knudson, Greiner, A.> ;Journal of Clinical Laboratory Analysis. 2022 Apr 1
Limited Variation between SARS-CoV-2-Infected Individuals in Domain Specificity and Relative Potency of the Antibody Response against the Spike Glycoprotein.
Hanora A Van Ert, Dana W Bohan, Kai Rogers, Mohammad Fili, Roberth A Rojas Chávez, Enya Qing, Changze Han, Spencer Dempewolf, Guiping Hu, Nathan Schwery, Kristina Sevc...> ;Microbiology Spectrum. 2022 Feb 23
10 citations
SARS-CoV-2 antibody changes in patients receiving COVID-19 convalescent plasma from normal and vaccinated donors
Judith Leon, Anna E. Merrill, Kai Rogers, Julie Kurt, Spencer Dempewolf, Alexandra Ehlers, J. Brooks Jackson, C. Michael Knudson> ;Transfusion and Apheresis Science. 2021 Nov 23
19 citations
Exponential increase in neutralizing and spike specific antibodies following vaccination of COVID-19 convalescent plasma donors.
Molly A. Vickers, Alan Sariol, Judith Leon, Alexandra Ehlers, Aaron V. Locher, Kerry A. Dubay, Laura Collins, Dena R. Voss, Abby E. Odle, Myrl Holida, Anna E. Merrill,...> ;Transfusion. 2021 Apr 8
1 citations
COVID-19 convalescent plasma; time for "goal directed therapy"?
Charles Michael Knudson, J. Brooks Jackson> ;Transfusion. 2021 Mar 26
322 citations
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice.
Jian Zheng, Lok-Yin Roy Wong, Kun Li, Abhishek Kumar Verma, M. Ortiz, Christine L. Wohlford-Lenane, Mariah R. Leidinger, C. Michael Knudson, David K. Meyerholz, Paul B...> ;Nature. 2021 Jan 28
13 citations
K18-hACE2 Mice for Studies of COVID-19 Treatments and Pathogenesis Including Anosmia
Stanley Perlman, Jian Zheng, Lok Yin Roy Wong, Kun Li, Abhishek Kumar Verma, Miguel E Ortiz Bezara, Christine L. Wohlford-Lenane, Mariah R. Leidinger, Michael C. Kunds...> ;Biorxiv. 2020 Aug 10
17 citations
COVID-19 convalescent plasma: phase 2.
C. Michael Knudson, J. Brooks Jackson> ;Transfusion. 2020 Jun 1
18 citations
ABO‐incompatible platelets are associated with increased transfusion reaction rates
Natalie M Malvik, Judith Leon, Annette J. Schlueter, Chaorong Wu, C. Michael Knudson> ;Transfusion. 2020 Feb 1
False positive testing for sickle hemoglobin in a blood donor with mild erythrocytosis and hemoglobin Geldrop St. Anna.
Craig D. Dunseth, Annette J. Schlueter, C. Michael Knudson> ;Transfusion and Apheresis Science. 2020 Jan 9
2 citations
Predicting changes in hemoglobin S after simple transfusion using complete blood counts.
Gagan Mathur, Patrick Ten Eyck, C. Michael Knudson> ;Transfusion. 2018 Jan 1
5 citations
Factors influencing platelet clumping during peripheral blood hematopoietic stem cell collection.
Gagan Mathur, Sarah L. Mott, Laura Collins, Gail A. Nelson, C. Michael Knudson, Annette J. Schlueter> ;Transfusion. 2017 May 1
16 citations
2-Deoxy-d-glucose Suppresses the In Vivo Antitumor Efficacy of Erlotinib in Head and Neck Squamous Cell Carcinoma Cells.
Arya Sobhakumari, Kevin P. Orcutt, Laurie Love-Homan, Christopher E. Kowalski, Arlene D. Parsons, C. Michael Knudson, Andrean L. Simons> ;Oncology Research. 2016 Jan 1
6 citations
Pathology Milestones: Assessing Clinical Competency by Committee.
J. Stacey Klutts, Leana Guerin, Leslie A. Bruch, Dennis J. Firchau, C. Michael Knudson, Nancy S. Rosenthal, Megan I. Samuelson, Chris S. Jensen, Janet L. Delwiche, Mat...> ;Academic Pathology. 2015 Oct 30
60 citations
The heritability of hemolysis in stored human red blood cells.
Thomas J. van ‘t Erve, Brett A. Wagner, Sean M. Martin, C. Michael Knudson, Robyn Blendowski, Mignon A. Keaton, Tracy Holt, John R. Hess, Garry R. Buettner, Kelli K. R...> ;Transfusion. 2015 Jun 1
40 citations
Visual and functional demonstration of growing Bax-induced pores in mitochondrial outer membranes
Laura A. Gillies, Han Du, Bjoern Peters, C. Michael Knudson, Donald D. Newmeyer, Tomomi Kuwana> ;Molecular Biology of the Cell. 2015 Jan 15
48 citations
The heritability of metabolite concentrations in stored human red blood cells.
Thomas J. van ‘t Erve, Brett A. Wagner, Sean M. Martin, C. Michael Knudson, Robyn Blendowski, Mignon A. Keaton, Tracy Holt, John R. Hess, Garry R. Buettner, Kelli K. R...> ;Transfusion. 2014 Aug 1
4 citations
Low-dose radiation-induced enhancement of thymic lymphomagenesis in Lck-Bax mice is dependent on LET and gender.
James A. Jacobus, Chester G. Duda, Mitchell C. Coleman, Sean M. Martin, Kranti A. Mapuskar, Gaowei Mao, Brian J. Smith, Nukhet Aykin-Burns, Peter Guida, David Gius, Fr...> ;Radiation Research. 2013 Jul 2
142 citations
The TCF-1 and LEF-1 Transcription Factors Have Cooperative and Opposing Roles in T Cell Development and Malignancy
Shuyang Yu, Xinyuan Zhou, Farrah C. Steinke, Chengyu Liu, Shann Ching Chen, Oksana Zagorodna, Xuefang Jing, Yoshifumi Yokota, David K. Meyerholz, Charles G. Mullighan,...> ;Immunity. 2012 Nov 16
59 citations
Susceptibility of Human Head and Neck Cancer Cells to Combined Inhibition of Glutathione and Thioredoxin Metabolism
Arya Sobhakumari, Laurie Love-Homan, Elise V.M. Fletcher, Sean M. Martin, Arlene D. Parsons, Douglas R. Spitz, C. Michael Knudson, Andrean L. Simons> ;Plos One. 2012 Oct 31
62 citations
Cell of origin strongly influences genetic selection in a mouse model of T-ALL
Katherine E. Berquam-Vrieze, Kishore Nannapaneni, Benjamin T. Brett, Linda Holmfeldt, Jing Ma, Oksana Zagorodna, Nancy A. Jenkins, Neal G. Copeland, David K. Meyerholz...> ;Blood. 2011 Oct 27
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Hospital Affiliations

Iowa City VA Health SystemIowa City, Iowa
University of Iowa Hospitals and ClinicsIowa City, Iowa