Charles J. Ryan MD

Oncology•Middletown, NJ

Genitourinary Oncology, Hematologic Oncology

Member and Attending Genitourinary Oncology Service Memorial Sloan Kettering Cancer Center

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480 Red Hill RoadMiddletown, NJ 07748

Education & Training

Memorial Sloan Kettering Cancer CenterFellowship, Hematology and Medical Oncology, 2000 - 2003
University of Wisconsin Hospitals and ClinicsResidency, Internal Medicine, 1996 - 2000
University of Wisconsin School of Medicine & Public HealthClass of 1996

Certifications & Licensure

CA State Medical License 2003 - 2026
NY State Medical License 2000 - 2026
NJ State Medical License 2024 - 2025
MN State Medical License 2018 - 2023

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013

Clinical Trials

Ketoconazole, Hydrocortisone, and GM-CSF in Treating Patients With Progressive Prostate Cancer After Hormone Therapy Start of enrollment: 2004 Apr 01
Completed
Phase 2
Nordihydroguaiaretic Acid in Treating Patients With Nonmetastatic Relapsed Prostate Cancer Start of enrollment: 2005 Jun 01
Terminated
Phase 1
Sorafenib and RAD001 Renal Cell Carcinoma Start of enrollment: 2006 Oct 01
Completed
Phase 1
Sandostatin for Patients With Androgen Independent Prostate Cancer Start of enrollment: 2007 Jul 01
Terminated
Phase 2
Ketoconazole and Dexamethasone in Prostate Cancer Start of enrollment: 2009 Dec 11
Completed
Phase 2
Abiraterone Post Ketoconazole for Prostate Cancer Start of enrollment: 2010 Sep 10
Completed
Phase 2
Neoadjuvant BKM120 in High-risk Prostate Cancer Start of enrollment: 2013 Apr 23
Terminated
Phase 2
A Multicenter Phase I/II Trial of Abiraterone Acetate + BEZ235 in Metastatic, Castration-Resistant Prostate Cancer Start of enrollment: 2013 Jan 31
Terminated
Phase 1, Phase 2
Selinexor in Treating Patients With Abiraterone Acetate and/or Enzalutamide Refractory Metastatic Castration-Resistant Prostate Cancer Start of enrollment: 2014 Sep 02
Terminated
Phase 2
Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or Enzalutamide Start of enrollment: 2021 Aug 17
ACTIVE_NOT_RECRUITING
PHASE2
INTense ExeRcise for SurviVAL Among Men with Metastatic Prostate Cancer (INTERVAL - GAP4)
ACTIVE_NOT_RECRUITING
NA
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

Genetic Drivers of Quality of Life in Prostate Cancer: An Evaluation of Genetic Polymorphisms and Patient-reported Outcomes in the E3805 CHAARTED trial.
Daniel Sentana-Lledo, Xiangying Chu, Charles J Ryan, Arjun Gupta, Christopher J Sweeney
European Urology Oncology. 2025-04-16
The Influence of the GermlineAdrenal-Permissive Allele (c.1100 C) on the Somatic Alteration Landscape, the Transcriptome, and Immune Cell Infiltration in Prostate Cancer.
Samuel Kellen, Allison Makovec, Carly D Miller, Shayan S Nazari, Andrew Elliott
Cancers. 2025-04-09
What's in a Name? Why Words Matter in Advanced Prostate Cancer.
William K Oh, Neeraj Agarwal, Alan Bryce, Pedro Barata, Courtney Bugler
European Urology. 2025-02-01

Lectures

Considerations for Systemic Therapy in Optimal Management of Oligometastatic Disease
ASCO Annual Meeting 2019 - Chicago, IL - 6/2/2019

Other

Castrate resistant prostate cancer: Treatments targeting the androgen pathway
Ryan CJ, Dawson NA
http://www.uptodate.com/contents/castrate-resistant-prostate-cancer-treatments-targeting-the-androge
UpToDate, Wolters Kluwer Health - 2013-02-21

Press Mentions

What to Know About Complementary Therapies for Prostate CancerDecember 13th, 2024
Successes and Setbacks in Prostate Cancer Care: Seeking the Right Treatment for the Right Patient at the Right TimeJuly 23rd, 2024
The Prostate Cancer Foundation Launches ‘Black Men: Know Your Risk’ Campaign and Teams up with Atlanta Hawks for ‘Black History Month Assist Challenge’ to Raise Awareness and Funds for Prostate Cancer ResearchFebruary 1st, 2023
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