CharlesESparksMD

PubMed

• 7 citations
  An Allosteric Binding Site on Sortilin Regulates the Trafficking of VLDL, PCSK9, and LDLR in Hepatocytes.
  Robert P. Sparks, Andres S. Arango, Jermaine L. Jenkins, Wayne C. Guida, Emad Tajkhorshid, Charles E. Sparks, Janet D. Sparks, Rutilio A. Fratti> ;Biochemistry. 2020 Nov 5
• 13 citations
  Low Serum Paraoxonase-1 Activity Associates with Incident Cardiovascular Disease Risk in Subjects with Concurrently High Levels of High-Density Lipoprotein Cholesterol...
  James P. Corsetti, Charles E. Sparks, Richard W. James, Stephan J. L. Bakker, Robin P. F. Dullaart> ;Journal of Clinical Medicine. 2019 Sep 1
• 3 citations
  Compositional Features of HDL Particles Interact with Albuminuria to Modulate Cardiovascular Disease Risk.
  James P. Corsetti, Stephan J. L. Bakker, Ron T. Gansevoort, Eke G. Gruppen, Margery A. Connelly, Charles E. Sparks, Robin P. F. Dullaart> ;International Journal of Molecular Sciences. 2019 Feb 23
• 3 citations
  Insulin resistance involvement in prevalence of familial dysbetalipoproteinemia in ε2ε2 subjects by Bayesian network modeling.
  James P. Corsetti, Tanzy Love, Charles E. Sparks, Stephan J. L. Bakker, Robin P. F. Dullaart> ;Clinical Biochemistry. 2018 Jun 18
• 6 citations
  Roles of high apolipoprotein E blood levels and HDL in development of familial dysbetalipoproteinemia in ε2ε2 subjects.
  James P. Corsetti, Charles E. Sparks, Stephan J. L. Bakker, Eke G. Gruppen, Robin P. F. Dullaart> ;Clinical Biochemistry. 2018 Feb 1
• 1 citations
  Autophagy and hepatic steatosis.
  Charles E. Sparks, Janet D. Sparks> ;Current Opinion in Lipidology. 2017 Aug 1
• 1 citations
  Inflammatory markers modify the risk of recurrent coronary events associated with apolipoprotein A-I in postinfarction patients
  Meng Wang, James P. Corsetti, Scott McNitt, David Q. Rich, Charles E. Sparks, Arthur J. Moss, Wojciech Zareba> ;Journal of Clinical Lipidology. 2017 Jan 1
• 8 citations
  Phosphatidylinositol (3,4,5)-trisphosphate binds to sortilin and competes with neurotensin: Implications for very low density lipoprotein binding.
  Robert P. Sparks, Jermaine L. Jenkins, Gregory E. Miner, Yan Wang, Wayne C. Guida, Charles E. Sparks, Rutilio A. Fratti, Janet D. Sparks> ;Biochemical and Biophysical Research Communications. 2016 Oct 21
• 10 citations
  Sortilin facilitates VLDL-B100 secretion by insulin sensitive McArdle RH7777 cells.
  Robert P. Sparks, Wayne C. Guida, Mark P. Sowden, Jermaine L. Jenkins, Matthew L. Starr, Rutilio A. Fratti, Charles E. Sparks, Janet D. Sparks> ;Biochemical and Biophysical Research Communications. 2016 Sep 16
• 2 citations
  Data in support of a central role of plasminogen activator inhibitor-2 polymorphism in recurrent cardiovascular disease risk in the setting of high HDL cholesterol and...
  James P. Corsetti, Peter Salzman, Daniel H. Ryan, Arthur J. Moss, Wojciech Zareba, Charles E. Sparks> ;Data in Brief. 2016 Sep 1
• 9 citations
  Influences on plasminogen activator inhibitor-2 polymorphism-associated recurrent cardiovascular disease risk in patients with high HDL cholesterol and inflammation
  James P. Corsetti, Peter Salzman, Daniel H. Ryan, Arthur J. Moss, Wojciech Zareba, Charles E. Sparks> ;Atherosclerosis. 2016 Jul 1
• 4 citations
  Insulin dependent apolipoprotein B degradation and phosphatidylinositide 3-kinase activation with microsomal translocation are restored in McArdle RH7777 cells followi...
  Janet D. Sparks, Amy L. Magra, Jeffrey M. Chamberlain, Colleen O’Dell, Charles E. Sparks> ;Biochemical and Biophysical Research Communications. 2016 Jan 8
• 9 citations
  The enigmatic role of sortilin in lipoprotein metabolism.
  Charles E. Sparks, Robert P. Sparks, Janet D. Sparks> ;Current Opinion in Lipidology. 2015 Dec 1
• 3 citations
  Insulin resistance predicts the risk for recurrent coronary events in post-infarction patients
  Barbara Szepietowska, Scott McNitt, Valentina Kutyifa, Daniel H. Ryan, James P. Corsetti, Charles E. Sparks, Arthur J. Moss, Wojciech Zareba> ;Cardiology Journal. 2015 Jan 1
• 12 citations
  Apolipoprotein B Attenuates Albuminuria-Associated Cardiovascular Disease in Prevention of Renal and Vascular Endstage Disease (PREVEND) Participants
  James P. Corsetti, Ron T. Gansevoort, Stephan J. L. Bakker, Charles E. Sparks, Priya Vart, Robin P. F. Dullaart> ;Journal of the American Society of Nephrology. 2014 Dec 1
• High-density lipoproteins: taking the good with the bad.
  Charles E. Sparks, James P. Corsetti, Janet D. Sparks> ;Current Opinion in Lipidology. 2014 Jun 1
• 2 citations
  Hepatic postprandial transition and very low-density lipoprotein biogenesis.
  Charles E. Sparks, Janet D. Sparks> ;Current Opinion in Lipidology. 2013 Oct 1
• 11 citations
  Plasminogen activator inhibitor-2 polymorphism associates with recurrent coronary event risk in patients with high HDL and C-reactive protein levels.
  James P. Corsetti, Peter Salzman, Daniel H. Ryan, Arthur J. Moss, Wojciech Zareba, Charles E. Sparks> ;Plos One. 2013 Jul 9
• 16 citations
  Insulin-dependent apolipoprotein B degradation is mediated by autophagy and involves class I and class III phosphatidylinositide 3-kinases
  Janet D. Sparks, Colleen O’Dell, Jeffrey M. Chamberlain, Charles E. Sparks> ;Biochemical and Biophysical Research Communications. 2013 Jun 14
• 32 citations
  Insulin suppression of apolipoprotein B in McArdle RH7777 cells involves increased sortilin 1 interaction and lysosomal targeting.
  Jeffrey M. Chamberlain, Colleen O’Dell, Charles E. Sparks, Janet D. Sparks> ;Biochemical and Biophysical Research Communications. 2013 Jan 4
• 16 citations
  Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation
  Nhat Tu Le, James P. Corsetti, Janet L. Dehoff-Sparks, Charles E. Sparks, Keigi Fujiwara, Jun Ichi Abe> ;International Journal of Inflammation. 2012 Sep 6
• 149 citations
  Selective Hepatic Insulin Resistance, VLDL Overproduction, and Hypertriglyceridemia
  Janet D. Sparks, Charles E. Sparks, Khosrow Adeli> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2012 Sep 1
• 3 citations
  Hepatic steatosis and VLDL hypersecretion.
  Charles E. Sparks, Janet D. Sparks> ;Current Opinion in Lipidology. 2012 Aug 1
• 26 citations
  Apolipoprotein E predicts incident cardiovascular disease risk in women but not in men with concurrently high levels of high-density lipoprotein cholesterol and C-reac...
  James P. Corsetti, Ron T. Gansevoort, Stephan J. L. Bakker, Gerjan Navis, Charles E. Sparks, Robin P. F. Dullaart> ;Metabolism. 2012 Jul 1
• 45 citations
  Apolipoprotein A-II Influences Apolipoprotein E-Linked Cardiovascular Disease Risk in Women with High Levels of HDL Cholesterol and C-Reactive Protein
  James P. Corsetti, Stephan J. L. Bakker, Charles E. Sparks, Robin P. F. Dullaart> ;Plos One. 2012 Jun 18
• Join now to see all