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Office
3400 Spruce St
Philadelphia, PA 19104Phone+1 215-662-4000- Is this information wrong?
Summary
- Dr. Charu Aggarwal is the Leslye Heisler Assistant Professor of Medicine in the Hematology-Oncology Division at the University of Pennsylvania’s Perelman School of Medicine. She is an active member of the Abramson Cancer Center (ACC) where she serves as Physician Leader for the clinical research program for Airways Malignancies.
Dr. Aggarwal specializes in the management of patients with lung and head and neck cancer, with a specific and clinical research focus on the development of novel immunotherapeutic approaches, and the discovery and application of biomarkers to guide therapy and monitor treatment. She serves as the local and national principle investigator for multiple clinical trials focusing on the development of “targeted” immunotherapeutic approaches including cellular therapy and CAR-T for solid tumors. Dr. Aggarwal has led the development of a DNA plasmid based HPV specific immunotherapy for HPV associated head and neck cancers. She is actively involved in evaluating the role of plasma-based NGS in management of patients with metastatic lung cancer.
Education & Training
- Temple University HospitalFellowship, Hematology and Medical Oncology, 2008 - 2011
- University at BuffaloResidency, Internal Medicine, 2005 - 2008
- Lady Hardinge Medical CollegeClass of 2003
Certifications & Licensure
- PA State Medical License 2008 - 2024
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013
Clinical Trials
- Cisplatin and Etoposide With or Without Veliparib in Treating Patients With Extensive Stage Small Cell Lung Cancer Start of enrollment: 2012 Sep 28
- Etirinotecan Pegol (NKTR-102) in NSCLC Start of enrollment: 2013 Jan 01
- Intrapleural AdV-tk Therapy in Patients With Malignant Pleural Effusion Start of enrollment: 2013 Oct 01
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Publications & Presentations
PubMed
- Brief Report: Impact of Reflex Testing on Tissue-Based Molecular Genotyping in Patients With Advanced Non-Squamous Non-Small Cell Lung Cancer.Melina E Marmarelis, Dylan G Scholes, Cindy M McGrath, Salvatore F Priore, Jacquelyn J Roth, Michael Feldman, Jennifer J D Morrissette, Leslie Litzky, Charu Deshpande,...> ;Clinical Lung Cancer. 2024 Mar 12
- Outcomes in patients treated with frontline immune checkpoint inhibition (ICI) for advanced NSCLC with KRAS mutations and STK11/KEAP1 comutations across PD-L1 levels.Lova Sun, Elizabeth A Handorf, Yunyun Zhou, Hossein Borghaei, Charu Aggarwal, Jessica Bauman> ;Lung Cancer. 2024 Apr 1
- Acute hospitalizations after proton therapy versus intensity-modulated radiotherapy for locally advanced non-small cell lung cancer in the durvalumab era.Iocolano, M., Yegya-Raman, N., Friedes, C., Wang, X., Kegelman, T., Lee, S., Duan, L., Li, B., Levin, W., Cengel, K., Konski, A., Langer, C., Cohen, R., Sun, L., Aggar...> ;Cancer. 2024 Jan 31
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Journal Articles
- Cisplatin Versus Cetuximab with Definitive Concurrent Radiotherapy for Head and Neck Squamous Cell Carcinoma: An Analysis of Veterans Health Affairs DataRavi Vinnakota, Keith Sigel, Joshua M Bauml, Roger B Cohen, Nevena Damjanov, Corey J Langer, Ronac Mamtani, Charu Aggarwal, Christina Knepley, Juan Wisnivesky, Cancer
- Immunotherapy Targeting HPV 16/18 Generates Potent Immune Responses in HPV-Associated Head and Neck CancerGregory S Weinstein, Charu Aggarwal, Roger B Cohen, Joshua Bauml, Alexander Lin, Clinical Cancer Research
- Thoracic Imaging of Non-Small Cell Lung Cancer Treated with Anti-Programmed Death Receptor-1 TherapySharyn I Katz, Arun C Nachiappan, Joshua Bauml, Stephen Bagley, Charu Aggarwal, Corey Langer, ScienceDirect
Press Mentions
- More “Bang for the Buck?” Keys to Decision-Making in Perioperative Early-Stage NSCLCMay 5th, 2023
- “Damning It with Faint Praise?” the Future of Anti-TIGIT Therapy in NSCLCApril 24th, 2023
- Remembering Famed Film Critic Roger Ebert 10 Years After Passing from Cancer: The Incredible Advancements in Head and Neck Cancer TreatmentApril 5th, 2023
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Hospital Affiliations
- Hospital of the University of PennsylvaniaPhiladelphia, Pennsylvania
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