ChinyuGSuMD

PubMed

• Early recapture of response with tofacitinib 10 mg twice daily in patients with ulcerative colitis in OCTAVE Open following dose reduction or treatment interruption in...
  Jessica R Allegretti, Krisztina B Gecse, Michael V Chiorean, Marjorie Argollo, Xiang Guo, Nervin Lawendy, Chinyu Su, Rajiv Mundayat, Jerome Paulissen, Leonardo Salese,...> ;Journal of Gastroenterology and Hepatology. 2024 Feb 1
• 2 citations
  Major Adverse Cardiovascular Events by Baseline Cardiovascular Risk in Patients with Ulcerative Colitis Treated with Tofacitinib: Data from the OCTAVE Clinical Programme.
  Stefan Schreiber, David T Rubin, Siew C Ng, Laurent Peyrin-Biroulet, Silvio Danese, Irene Modesto, Xiang Guo, Chinyu Su, Kenneth K Kwok, Hyejin Jo, Yan Chen, Arne Ynde...> ;Journal of Crohn's & Colitis. 2023 Nov 24
• Long-Term Improvement in the Patient-Reported Outcomes of Rectal Bleeding, Stool Frequency, and Health-Related Quality of Life with Tofacitinib in the Ulcerative Colit...
  David P Hudesman, Joana Torres, Leonardo Salese, John C Woolcott, Rajiv Mundayat, Chinyu Su, Mahmoud H Mosli, Jessica R Allegretti> ;The Patient. 2023 Mar 1
• Impact of Concomitant Corticosteroids on Tofacitinib Induction Efficacy and Infection Rates in Ulcerative Colitis.
  Gary R Lichtenstein, Benjamin L Cohen, Leonardo Salese, Irene Modesto, Wenjin Wang, Gary Chan, Haytham Mohamed Ahmed, Chinyu Su, Laurent Peyrin-Biroulet> ;Digestive Diseases and Sciences. 2023 Jun 1
• 6 citations
  Association of C-reactive Protein and Partial Mayo Score With Response to Tofacitinib Induction Therapy: Results From the Ulcerative Colitis Clinical Program.
  Marla C Dubinsky, Fernando Magro, Flavio Steinwurz, David P Hudesman, Jami A Kinnucan, Ryan C Ungaro, Markus F Neurath, Nicole Kulisek, Jerome Paulissen, Chinyu Su, Da...> ;Inflammatory Bowel Diseases. 2023 Jan 5
• 6 citations
  Long-term Risk of Herpes Zoster Infection in Patients With Ulcerative Colitis Receiving Tofacitinib.
  Kevin L Winthrop, Séverine Vermeire, Millie D Long, Julian Panés, Siew C Ng, Nicole Kulisek, Rajiv Mundayat, Nervin Lawendy, Ivana Vranic, Irene Modesto, Chinyu Su, Gi...> ;Inflammatory Bowel Diseases. 2023 Jan 5
• 11 citations
  Assessment of Safety and Efficacy of Tofacitinib, Stratified by Age, in Patients from the Ulcerative Colitis Clinical Program.
  Gary R Lichtenstein, Brian Bressler, Carlos Francisconi, Severine Vermeire, Nervin Lawendy, Leonardo Salese, Gosford Sawyerr, Hongjiong Shi, Chinyu Su, Donna T Judd, T...> ;Inflammatory Bowel Diseases. 2023 Jan 5
• 1 citations
  Presence of risk factors associated with colectomy among patients with ulcerative colitis: aanalysis of data from the tofacitinib OCTAVE ulcerative colitis clinical pr...
  David T Rubin, Leonardo Salese, Mitchell Cohen, Paulo G Kotze, John C Woolcott, Chinyu Su, Rajiv Mundayat, Jerome Paulissen, Joana Torres, Millie D Long> ;Therapeutic Advances in Gastroenterology. 2023 Jan 1
• 20 citations
  Tofacitinib for the Treatment of Ulcerative Colitis: An Integrated Summary of up to 7.8 Years of Safety Data from the Global Clinical Programme.
  William J Sandborn, Geert R D'Haens, Bruce E Sands, Remo Panaccione, Siew C Ng, Nervin Lawendy, Nicole Kulisek, Irene Modesto, Xiang Guo, Rajiv Mundayat, Chinyu Su, Iv...> ;Journal of Crohn's & Colitis. 2023 Apr 3
• Bridging Efficacy of Tofacitinib Immediate-Release to Extended-Release Formulations for Treatment of Ulcerative Colitis: Application of a Model-Informed Drug Developme...
  Arnab Mukherjee, Shinichi Tsuchiwata, Cheng Chang, Timothy Nicholas, Chinyu Su, Vu H Le, Joseph Kushner, Nicole Kulisek> ;Clinical Pharmacology in Drug Development. 2022 Aug 1
• 1 citations
  Clostridium difficile Infection in Patients with Ulcerative Colitis Treated with Tofacitinib in the Ulcerative Colitis Program.
  Edward V Loftus, Daniel C Baumgart, Krisztina Gecse, Jami A Kinnucan, Susan B Connelly, Leonardo Salese, Chinyu Su, Kenneth K Kwok, John C Woolcott, Alessandro Armuzzi> ;Inflammatory Bowel Diseases. 2023 May 2
• 4 citations
  Exposure-Response Characterization of Tofacitinib Efficacy in Moderate to Severe Ulcerative Colitis: Results From Phase II and Phase III Induction and Maintenance Stud...
  Arnab Mukherjee, Shinichi Tsuchiwata, Timothy Nicholas, Jack A Cook, Irene Modesto, Chinyu Su, Geert R D'Haens, William J Sandborn> ;Clinical Pharmacology and Therapeutics. 2022 Jul 1
• 4 citations
  Modified Mayo scoreMayo score for evaluation of treatment efficacy in patients with ulcerative colitis: data from the tofacitinib OCTAVE program.
  William J Sandborn, Bruce E Sands, Séverine Vermeire, Yvette Leung, Xiang Guo, Irene Modesto, Chinyu Su, Wenjin Wang, Julian Panés> ;Therapeutic Advances in Gastroenterology. 2022 Jan 1
• 62 citations
  Safety and efficacy of tofacitinib for treatment of ulcerative colitis: final analysis of OCTAVE Open, an open-label, long-term extension study with up to 7.0 years of...
  William J. Sandborn, Nervin Lawendy, Silvio Danese, Chinyu Su, Edward V. Loftus, Ailsa Hart, Iris Dotan, Aderson Omar Mourão Cintra Damião, Donna T. Judd, Xiang Guo, I...> ;Alimentary Pharmacology & Therapeutics. 2021 Dec 1
• 3 citations
  Agreement between local and central reading of endoscopic disease activity in ulcerative colitis: results from the tofacitinib OCTAVE trials.
  Brian G. Feagan, Reena Khanna, William J. Sandborn, Severine Vermeire, Walter Reinisch, Chinyu Su, Leonardo Salese, Haiyun Fan, Jerome Paulissen, Deborah A Woodworth, ...> ;Alimentary Pharmacology & Therapeutics. 2021 Oct 6
• 16 citations
  Tofacitinib Treatment Safety in Moderate to Severe Ulcerative Colitis: Comparison of Observational Population Cohort Data From the IBM MarketScan® Administrative Claim...
  Jeffrey R. Curtis, Miguel Regueiro, Huifeng Yun, Chinyu Su, Marco DiBonaventura, Nervin Lawendy, Chudy I. Nduaka, Nana Koram, Joseph C. Cappelleri, Gary Chan, Irene Mo...> ;Inflammatory Bowel Diseases. 2021 Aug 19
• 8 citations
  Characterization of Creatine Kinase Levels in Tofacitinib-Treated Patients with Ulcerative Colitis: Results from Clinical Trials.
  Remo Panaccione, John D Isaacs, Lea Ann Chen, Wenjin Wang, Amy Marren, Kenneth Kwok, Lisy Wang, Gary Chan, Chinyu Su> ;Digestive Diseases and Sciences. 2021 Aug 1
• 25 citations
  Tofacitinib for the Treatment of Ulcerative Colitis: Analysis of Infection Rates from the Ulcerative Colitis Clinical Programme
  Kevin L. Winthrop, Edward V. Loftus, Daniel C. Baumgart, Walter Reinisch, Chudy I. Nduaka, Nervin Lawendy, Gary Chan, Rajiv Mundayat, Gary S. Friedman, Leonardo Salese...> ;Journal of Crohn's & Colitis. 2021 Jun 22
• 13 citations
  Lipid Profiles in Patients With Ulcerative Colitis Receiving Tofacitinib-Implications for Cardiovascular Risk and Patient Management.
  Bruce E. Sands, Jean-Frederic Colombel, Christina Ha, Michel Farnier, Alessandro Armuzzi, Daniel Quirk, Gary S. Friedman, Kenneth Kwok, Leonardo Salese, Chinyu Su, Pam...> ;Inflammatory Bowel Diseases. 2021 May 17
• 12 citations
  Tofacitinib, an Oral Janus Kinase Inhibitor: Analysis of Malignancy (Excluding Nonmelanoma Skin Cancer) Events Across the Ulcerative Colitis Clinical Program.
  Gary R. Lichtenstein, Gerhard Rogler, Matthew A. Ciorba, Chinyu Su, Gary Chan, Ronald Pedersen, Nervin Lawendy, Daniel Quirk, Chudy I. Nduaka, Andrew John Thorpe, Juli...> ;Inflammatory Bowel Diseases. 2021 May 17
• 12 citations
  Tofacitinib for the Treatment of Ulcerative Colitis: Analysis of Nonmelanoma Skin Cancer Rates From the Ulcerative Colitis Clinical Program.
  Bruce E. Sands, Millie D. Long, Walter Reinisch, Julián Panés, Edward V. Loftus, Chudy I. Nduaka, Arif Soonasra, Rajiv Mundayat, Nervin Lawendy, Gary Chan, Gary S. Fri...> ;Inflammatory Bowel Diseases. 2021 Mar 20
• 33 citations
  Efficacy and Safety of Tofacitinib in Ulcerative Colitis Based on Prior Tumor Necrosis Factor Inhibitor Failure Status
  William J. Sandborn, Laurent Peyrin-Biroulet, Ala I. Sharara, Chinyu Su, Irene Modesto, Rajiv Mundayat, L. Mert Gunay, Leonardo Salese, Bruce E. Sands> ;Clinical Gastroenterology and Hepatology. 2021 Mar 6
• 9 citations
  Population Pharmacokinetics of Tofacitinib in Patients With Moderate to Severe Ulcerative Colitis
  Camille Vong, Steven W. Martin, Chenhui Deng, Rujia Xie, Kaori Ito, Chinyu Su, William J. Sandborn, Arnab Mukherjee> ;Clinical Pharmacology in Drug Development. 2021 Mar 1
• 28 citations
  Outcomes of Tofacitinib Dose Reduction in Patients with Ulcerative Colitis in Stable Remission from the Randomised RIVETING Trial.
  Severine Vermeire, Chinyu Su, Nervin Lawendy, Taku Kobayashi, William J. Sandborn, David T. Rubin, Irene Modesto, Sean Gardiner, Nicole Kulisek, Haiying Zhang, Wenjin ...> ;Journal of Crohn's & Colitis. 2020 Dec 8
• 29 citations
  Efficacy and Safety of Extended Induction With Tofacitinib for the Treatment of Ulcerative Colitis
  William J. Sandborn, Laurent Peyrin-Biroulet, Daniel Quirk, Wenjin Wang, Chudy I. Nduaka, Arnab Mukherjee, Chinyu Su, Bruce E. Sands> ;Clinical Gastroenterology and Hepatology. 2020 Oct 27
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