
Christian L Roth MD
Professor, Pediatrics, University of Washington School of Medicine
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4800 Sand Point Way NESeattle, WA 98105
Phone+1 206-987-2640
Fax+1 206-987-2720
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Summary
- Dr. Christian Roth is a pediatric endocrinologist based in Seattle, WA, who graduated from the University of Heidelberg Faculty of Medicine in 1990. His research focuses on obesity, diabetes, and eating behaviors in children, with multiple publications in prominent journals such as Metabolism, Obesity, and Current Obesity Reports. His work on hyperphagia and the melanocortin-4 receptor pathway is particularly noted, with some articles cited several times. Dr. Roth has also served as a principal investigator in various clinical trials related to hypothalamic obesity and weight management in children.
Education & Training
University of Heidelberg Faculty of MedicineClass of 1990
Certifications & Licensure
WA State Medical License 2006 - 2026
Clinical Trials
- Energy Balance & Weight Loss in Craniopharyngioma-related or Other Hypothalamic Tumors in Hypothalamic Obesity
- Setmelanotide Phase 2 Treatment Trial in Participants With Rare Genetic Disorders of Obesity Start of enrollment: 2017 Feb 10
- Pilot Study of Probiotics in Pre-diabetic Adolescents Start of enrollment: 2018 Jun 01
Publications & Presentations
PubMed
- 5 citationsCurrent and Future Pharmacological Interventions for Acquired Hypothalamic Obesity.Christian L Roth, Nathalie J Doelman-Oldenburger, Hanneke M van Santen
Drugs. 2026-04-01 - 4 citationsA melanocortin 4- and glucagon-like peptide 1 receptor multiple agonist for the treatment of diabetes and obesity.Emily F Ashlaw, Clinton T Elfers, Kylie S Chichura, Isabella Chavez Miranda, Aelish McGivney
Metabolism. 2026-01-01 - 6 citationsHyperphagia in rare melanocortin-4 receptor pathway diseases: therapeutic options and assessing treatment response.Jesús Argente, Karine Clément, Jessica Duis, I Sadaf Farooqi, Peter Kühnen
Reviews in Endocrine & Metabolic Disorders. 2025-12-01
Press Mentions
- Experimental Obesity Treatment Could Produce Weight Loss Without Surgery or NauseaMarch 29th, 2023
- 'Rebound' Weight Gain: A Disconnect Between Brain and Gut May Be a FactorSeptember 15th, 2022
- ‘Rebound’ Weight Gain: Brain, Gut DisconnectAugust 11th, 2022
Grant Support
- Phentermine/Topiramate in children, adolescents, and young adults with hypothalamic obesity: a pilot and feasibility studySEATTLE CHILDREN'S HOSPITAL2023–2027
- Development of Anorexigenic and Glucoregulatory Chimeric PeptidesSEATTLE CHILDREN'S HOSPITAL2023–2027
- Efficacy of Novel Melanocortin and Gut-peptide Dual Agonists for Childhood Obesity TreatmentSEATTLE CHILDREN'S HOSPITAL2024–2026
- Brain systems and behaviors underlying response to obesity treatment in childrenSEATTLE CHILDREN'S HOSPITAL2014–2025
Professional Memberships
- Member
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