ChristinaEleanorBarkauskasMD

Pulmonology • Durham, NC

Critical Care Medicine, Pleural Disease

Assistant Professor in the Department of Medicine, Duke University School of Medicine

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Office
40 Duke Medicine Circle
Clinic 2F/2G
Durham, NC 27710
Phone+1 919-620-5300
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Education & Training

Duke University HospitalFellowship, Pulmonary Disease and Critical Care Medicine, 2007 - 2011
Duke University HospitalResidency, Internal Medicine, 2004 - 2007
Duke University School of MedicineClass of 2004

Certifications & Licensure

NC State Medical License 2004 - 2024
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Publications & Presentations

PubMed

2 citations
Plasma Microbial Cell-Free DNA Sequencing in Immunocompromised Patients With Pneumonia: A Prospective Observational Study.
Stephen P Bergin, Roy F Chemaly, Sanjeet S Dadwal, Joshua A Hill, Yeon Joo Lee, Ghady Haidar, Alfred Luk, Alexander Drelick, Peter V Chin-Hong, Esther Benamu, Fareed K...> ;Clinical Infectious Diseases. 2024 Mar 20
3 citations
Transitional cell states sculpt tissue topology during lung regeneration.
Arvind Konkimalla, Satoshi Konishi, Lauren Macadlo, Yoshihiko Kobayashi, Zachary J Farino, Naoya Miyashita, Léa El Haddad, Jeremy Morowitz, Christina E Barkauskas, Pan...> ;Cell Stem Cell. 2023 Nov 2
1 citations
Intravenous aviptadil and remdesivir for treatment of COVID-19-associated hypoxaemic respiratory failure in the USA (TESICO): a randomised, placebo-controlled trial.
Samuel M Brown, Christina E Barkauskas, Birgit Grund, Shweta Sharma, Andrew N Phillips, Lindsay Leither, Ithan D Peltan, Michael Lanspa, Daniel L Gilstrap, Ahmad Moura...> ;The Lancet. Respiratory Medicine. 2023 Sep 1
15 citations
A Randomized Trial of Mesenchymal Stromal Cells for Moderate to Severe Acute Respiratory Distress Syndrome from COVID-19.
Michael E Bowdish, Christina E Barkauskas, Jessica R Overbey, Robert L Gottlieb, Keren Osman, Abhijit Duggal, Mary E Marks, Jonathan Hupf, Eustace Fernandes, Bradley G...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Feb 1
44 citations
Responses to a Neutralizing Monoclonal Antibody for Hospitalized Patients With COVID-19 According to Baseline Antibody and Antigen Levels : A Randomized Controlled Trial.
, Lundgren, J., Grund, B., Barkauskas, C., Holland, T., Gottlieb, R., Sandkovsky, U., Brown, S., Knowlton, K., Self, W., Files, D., Jain, M., Benfield, T., Bowdish, M....> ;Annals of Internal Medicine. 2022 Feb 1
6 citations
Design and implementation of an international, multi-arm, multi-stage platform master protocol for trials of novel SARS-CoV-2 antiviral agents: Therapeutics for Inpati...
Daniel D Murray, Abdel Babiker, Jason V. Baker, Christina E. Barkauskas, Samuel M. Brown, Christina C. Chang, Victoria J. Davey, Annetine C. Gelijns, Adit A. Ginde, Bi...> ;Clinical Trials. 2021 Oct 10
9 citations
Hyperpolarized 129Xe MRI and Spectroscopy of Gas-Exchange Abnormalities in Nonspecific Interstitial Pneumonia.
David G. Mummy, E. Bier, Ziyi Wang, Jennifer Korzekwinski, Lake Morrison, Christina E. Barkauskas, H. Page McAdams, Robert M. Tighe, Bastiaan Driehuys, Joseph G. Mamma...> ;Radiology. 2021 Jul 27
14 citations
What Does ARDS" Mean during the COVID-19 Pandemic?"
Samuel M. Brown, Ithan D. Peltan, Christina E. Barkauskas, Angela J. Rogers, Virginia L. Kan, Annetine C. Gelijns, B. Taylor Thompson> ;Annals of the American Thoracic Society. 2021 Jul 21
275 citations
A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19.
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;The New England Journal of Medicine. 2021 Mar 11
10 citations
Repetitive Ozone Exposures and Evaluation of Pulmonary Inflammation and Remodeling in Diabetic Mouse Strains.
James G. Wagner, Christina E. Barkauskas, Aaron Vose, Ryan P. Lewandowski, Jack R. Harkema, Robert M. Tighe> ;Environmental Health Perspectives. 2020 Nov 30
17 citations
Design and implementation of the multi-arm, multi-stage Therapeutics for Inpatients with COVID-19 (TICO) platform master protocol: An Accelerating COVID-19 Therapeutic...
Daniel D Murray, Abdel Babiker, Jason V. Baker, Christina E. Barkauskas, Samuel M. Brown, Christina C. Chang, Victoria J. Davey, Annetine C. Gelijns, Adit A. Ginde, Bi...> ;Medrxiv. 2020 Nov 12
3 citations
A Specialized Few Among Many: Identification of a Novel Lung Epithelial Stem Cell Population.
Christina E. Barkauskas> ;Cell Stem Cell. 2020 Mar 5
2 citations
Pathogenic Potential of Hic1-Expressing Cardiac Stromal Progenitors.
Hesham Soliman, Ben Paylor, R Wilder Scott, Dario R Lemos, ChihKai Chang, Martin Arostegui, Marcela Low, Christina Lee, Daniela Fiore, Paola Braghetta, Vendula Pospich...> ;Cell Stem Cell. 2020 Mar 5
17 citations
Pathogenic Potential of Hic1-Expressing Cardiac Stromal Progenitors.
Hesham Soliman, Ben Paylor, R Wilder Scott, Dario R Lemos, ChihKai Chang, Martin Arostegui, Marcela Low, Christina Lee, Daniela Fiore, Paola Braghetta, Vendula Pospich...> ;Cell Stem Cell. 2020 Feb 6
15 citations
Interleukin-13 disrupts type 2 pneumocyte stem cell activity
Kristen M Glisinski, Adam J Schlobohm, Sarah V Paramore, Anastasiya Birukova, M. Arthur Moseley, Matthew W. Foster, Christina E. Barkauskas> ;JCI Insight. 2020 Jan 16
3 citations
Ethylene Glycol Toxicity in the Setting of Recurrent Ingestion: A Case Report and Literature Review.
Daniel B. Loriaux, Stephen P. Bergin, Sweta M. Patel, Jesse Tucker, Christina E. Barkauskas> ;Cureus. 2019 Apr 3
154 citations
Niche-mediated BMP/SMAD signaling regulates lung alveolar stem cell proliferation and differentiation.
Mei-I Chung, Melissa Bujnis, Christina E. Barkauskas, Yoshihiko Kobayashi, Brigid L.M. Hogan> ;Development. 2018 May 1
242 citations
Lung organoids: current uses and future promise.
Christina E. Barkauskas, Mei-I Chung, Bryan A. Fioret, Xia Gao, Hiroaki Katsura, Brigid L.M. Hogan> ;Development. 2017 Mar 15
37 citations
Sec63 and Xbp1 regulate IRE1α activity and polycystic disease severity
Sorin V. Fedeles, Jae-Seon So, Amol Shrikhande, Seunghun Lee, Anna Rachel Gallagher, Christina E. Barkauskas, Stefan Somlo, Ann-Hwee Lee> ;The Journal of Clinical Investigation. 2015 May 1
224 citations
Telomere dysfunction causes alveolar stem cell failure
Jonathan K. Alder, Christina E. Barkauskas, Nathachit Limjunyawong, Susan E. Stanley, Frant Kembou, Rubin M. Tuder, Brigid L.M. Hogan, Wayne Mitzner, Mary Armanios> ;Proceedings of the National Academy of Sciences of the United States of America. 2015 Apr 21
200 citations
Plasticity of Hopx + type I alveolar cells to regenerate type II cells in the lung
Rajan Jain, Christina E. Barkauskas, Norifumi Takeda, Emily Bowie, Haig Aghajanian, Qiaohong Wang, Arun Padmanabhan, Lauren J. Manderfield, Mudit Gupta, Deqiang Li, Li...> ;Nature Communications. 2015 Apr 13
594 citations
Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function.
Brigid L.M. Hogan, Christina E. Barkauskas, Harold A. Chapman, Jonathan A. Epstein, Rajan Jain, Connie C. W. Hsia, Laura E. Niklason, Elizabeth A. Calle, Andrew V. Le,...> ;Cell Stem Cell. 2014 Aug 7
111 citations
Cellular Mechanisms of Tissue Fibrosis. 7. New insights into the cellular mechanisms of pulmonary fibrosis
Christina E. Barkauskas, Paul W. Noble> ;American Journal of Physiology. Cell Physiology. 2014 Jun 1
1041 citations
Type 2 alveolar cells are stem cells in adult lung
Christina E. Barkauskas, Michael J. Cronce, Craig R. Rackley, Emily Bowie, Douglas R. Keene, Barry R. Stripp, Scott H. Randell, Paul W. Noble, Brigid L.M. Hogan> ;The Journal of Clinical Investigation. 2013 Jul 1
79 citations
Stem cells of the adult lung: their development and role in homeostasis, regeneration, and disease
Carolien Wansleeben, Christina E. Barkauskas, Jason R. Rock, Brigid L.M. Hogan> ;Wiley Interdisciplinary Reviews. Developmental Biology. 2013 Jan 1
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