ChristinaLaukaitisMDPhD, FACP, FACMG(She/Her)

PubMed

• 1 citations
  Androgen-Binding Protein (Abp) Evolutionary History: Has Positive Selection Caused Fixation of Different Paralogs in Different Taxa of the Genus Mus?
  Robert C Karn, Golbahar Yazdanifar, Željka Pezer, Pierre Boursot, Christina M. Laukaitis> ;Genome Biology and Evolution. 2021 Oct 1
• 1 citations
  Physician practices in evaluation and treatment of patients with generalized joint hypermobility and bleeding.
  Nicole E. Kendel, Sarah H. O'Brien, Christina M. Laukaitis, Manjusha Kumar, Howard P. Levy, Rohith Jesudas> ;Blood Coagulation & Fibrinolysis. 2021 Dec 1
• 5 citations
  Subtle differences in autonomic symptoms in people diagnosed with hypermobile Ehlers-Danlos syndrome and hypermobility spectrum disorders.
  Kiana L. Martinez, Corina Mauss, Jennifer Andrews, Kathylynn Saboda, Julie M. Huynh, Alejandro J. Sanoja, Rohith Jesudas, Peter H. Byers, Christina M. Laukaitis> ;American Journal of Medical Genetics. Part A. 2021 Apr 7
• 23 citations
  Human rDNA copy number is unstable in metastatic breast cancers.
  Virginia Valori, Katalin Tus, Christina M. Laukaitis, David T. Harris, Lauren LeBeau, Keith A. Maggert> ;Epigenetics. 2020 Feb 1
• 9 citations
  An update on the new classification of Ehlers‐Danlos syndrome and review of the causes of bleeding in this population
  Rohith Jesudas, Ateefa Chaudhury, Christina M. Laukaitis> ;Haemophilia. 2019 Jun 10
• 2 citations
  Missense variants in TMEM67 in a patient with Joubert syndrome.
  Julie M. Huynh, Maureen K. Galindo, Christina M. Laukaitis> ;Clinical Case Reports. 2018 Oct 4
• 70 citations
  Repeat associated mechanisms of genome evolution and function revealed by the Mus caroli and Mus pahari genomes.
  David Thybert, Maša Roller, Fabio C. P. Navarro, Ian T. Fiddes, Ian Streeter, Christine Feig, David Martín-Gálvez, Mikhail Kolmogorov, Václav Janoušek, Wasiu Akanni, B...> ;Genome Research. 2018 Mar 21
• 5 citations
  Analysis of Copy Number Variation in the Abp Gene Regions of Two House Mouse Subspecies Suggests Divergence during the Gene Family Expansions
  Željka Pezer, Amanda G. Chung, Robert C. Karn, Christina M. Laukaitis> ;Genome Biology and Evolution. 2017 Jun 1
• 11 citations
  Studies of an Androgen-Binding Protein Knockout Corroborate a Role for Salivary ABP in Mouse Communication.
  Amanda G. Chung, Phillip M Belone, Barbora Vošlajerová Bímová, Robert C. Karn, Christina M. Laukaitis> ;Genetics. 2017 Apr 1
• 16 citations
  The Role of Retrotransposons in Gene Family Expansions in the Human and Mouse Genomes.
  Václav Janoušek, Christina M. Laukaitis, Alexey Yanchukov, Robert C. Karn> ;Genome Biology and Evolution. 2016 Sep 1
• 24 citations
  Panel testing reveals nonsense and missense CDH1 mutations in families without hereditary diffuse gastric cancer
  Julie M. Huynh, Christina M. Laukaitis> ;Molecular Genetics & Genomic Medicine. 2016 Jan 13
• 24 citations
  Constitutive expression of AhR and BRCA-1 promoter CpG hypermethylation as biomarkers of ERα-negative breast tumorigenesis
  Donato F. Romagnolo, Andreas J. Papoutsis, Christina M. Laukaitis, Ornella I. Selmin> ;BMC Cancer. 2015 Dec 29
• 159 citations
  A Phase 3 Trial of Sebelipase Alfa in Lysosomal Acid Lipase Deficiency.
  Barbara K. Burton, Manisha Balwani, François Feillet, Ivo Barić, T. Andrew Burrow, Carmen Camarena Grande, Mahmut Çoker, Alejandra Consuelo-Sanchez, Patrick Deegan, Ma...> ;The New England Journal of Medicine. 2015 Sep 9
• 6 citations
  Comparative Proteomics of Mouse Tears and Saliva: Evidence from Large Protein Families for Functional Adaptation
  Robert C. Karn, Christina M. Laukaitis> ;Proteomes. 2015 Sep 7
• 8 citations
  Did androgen-binding protein paralogs undergo neo- and/or Subfunctionalization as the Abp gene region expanded in the mouse genome?
  Robert C. Karn, Amanda G. Chung, Christina M. Laukaitis> ;Plos One. 2014 Dec 22
• 7 citations
  Selection shaped the evolution of mouse androgen-binding protein (ABP) function and promoted the duplication of Abp genes
  Robert C. Karn, Christina M. Laukaitis> ;Biochemical Society Transactions. 2014 Aug 1
• 13 citations
  Shared and Unique Proteins in Human, Mouse and Rat Saliva Proteomes: Footprints of Functional Adaptation
  Robert C. Karn, Amanda G. Chung, Christina M. Laukaitis> ;Proteomes. 2013 Dec 1
• 16 citations
  The role of retrotransposons in gene family expansions: insights from the mouse Abp gene family
  Václav Janoušek, Robert C. Karn, Christina M. Laukaitis> ;BMC Evolutionary Biology. 2013 May 29
• 5 citations
  An unusual BRCA mutation distribution in a high risk cancer genetics clinic
  Anna C. Nelson-Moseke, Joanne M. Jeter, Haiyan Cui, Denise J. Roe, Setsuko K. Chambers, Christina M. Laukaitis> ;Familial Cancer. 2013 Mar 1
• 9 citations
  The roles of gene duplication, gene conversion and positive selection in rodent Esp and Mup pheromone gene families with comparison to the Abp family.
  Robert C. Karn, Christina M. Laukaitis> ;Plos One. 2012 Oct 19
• 7 citations
  Chemoprevention in patients with genetic risk of colorectal cancers
  Christina M. Laukaitis, Steven H. Erdman, Eugene W. Gerner> ;Colorectal Cancer. 2012 Jun 27
• 8 citations
  Congenic strain analysis reveals genes that are rapidly evolving components of a prezygotic isolation mechanism mediating incipient reinforcement.
  Christina M. Laukaitis, Corina Mauss, Robert C. Karn> ;Plos One. 2012 Apr 25
• 2 citations
  Genetics for the General Internist
  Christina M. Laukaitis> ;The American Journal of Medicine. 2012 Jan 1
• 36 citations
  DFMO: Targeted risk reduction therapy for colorectal neoplasia
  Christina M. Laukaitis, Eugene W. Gerner> ;Best Practice & Research. Clinical Gastroenterology. 2011 Aug 1
• 11 citations
  Positive Selection Shaped the Convergent Evolution of Independently Expanded Kallikrein Subfamilies Expressed in Mouse and Rat Saliva Proteomes
  Robert C. Karn, Christina M. Laukaitis> ;Plos One. 2011 Jun 14
• Join now to see all

Journal Articles

• An Unusual BRCA Mutation Distribution in a High Risk Cancer Genetics Clinic  
  Nelson-Moseke, A.C*, Jeter, J.M., Cui, A., Roe, D.J., Chambers, S.K., and Laukaitis, C.M., Familial Cancer, 1/1/2013
• Congenic strain analysis reveals genes that are rapidly evolving components of a prezygotic isolation mediating incipient reinforcement  
  Karn, R.C., Mauss, C. and Laukaitis, C.M., PLOS One, 1/1/2012
• Genetics for the General Internist  
  Laukaitis, C.M., American Journal of Medicine, 1/1/2012
• Reinforcement selection acting on the European house mouse hybrid zone  
  Voslajerova Bimova, B., Macholan, M., Baird, S.E.B., Munclinger, P., Laukaitis, C.M., Karn, R.C., Luzynski, K., Tucker, P., Pialek, J., Molecular Ecology, 1/1/2011
• A Novel Defensive Mechanism against Acetaminophen Toxicity in the Mouse Lateral Nasal Gland: Role of CYP2A5-mediated regulation of testosterone homeostasis and salivar...  
  Zhou, X., Wei, Y., Xie, F., Laukaitis, C.M., Karn, R.C., Kluetzman, K., Gu, J., Zhang, Q-Y., Roberts, D.W., and Ding, X., Molecular Toxicology, 1/1/2011
• DFMO: Targeted Risk Reduction Therapy  
  Laukaitis, C.M. and Gerner, E.W., Best Practice and Research: Clinical Gastroenterology, 1/1/2011
• The mechanism of expansion and the volatility it created in three pheromone gene clusters in the mouse genome  
  Karn, R.C. and Laukaitis, C.M., Genome Biology and Evolution, 1/1/2009
• Diverse spatial, temporal, and sexual expression of recently duplicated androgen-binding protein genes in Mus musculus  
  Laukaitis, C.M., Dlouhy, S.R., Emes, R.D., Ponting, C.P., and Karn, R.C., BMC Evolutionary Biology, 1/1/2005
• Evolution of the secretoglobins: A genomic and proteomic view  
  Laukaitis, C.M. and Karn, R.C., Biological Journal of the Linnean Society, 1/1/2005
• The mouse salivary androgen-binding protein (ABP) gene cluster on chromosome 7: Characterization and evolutionary relationships  
  Laukaitis, C.M., Dlouhy, S.R., and Karn, R.C., Mammalian Genome, 1/1/2003
• Differential dynamics of 5 integrin, paxillin, and -actinin during formation and disassembly of adhesions in migrating cells  
  Laukaitis, C.M., Donais, K., Webb, D.J., and Horwitz, A.F., Journal of Cell Biology, 1/1/2001
• Salivary androgen-binding protein (ABP) mediates sexual isolation in Mus Musculus.  
  Laukaitis, C. M., Critser, E. S. and Karn, R. C, Evolution
• Visualizing cell migration in situ.  
  Knight, B., Laukaitis, C. M., Akhtar, N., Hotchin, N. A., Edlund, M. and Horwitz, A. R, Current Biology
• Differential dynamics of 5 integrin, paxillin, and -actinin during formation and disassembly of adhesions in migrating cells.  
  Laukaitis, C. M., Donais, K., Webb, D. J., and Horwitz, A. F, Journal of Cell Biology
• Rapid duplication and sequence diversification within the rodent androgen-binding protein (ABP) gene cluster.  
  Emes, R.D., Riley, M.C., Laukaitis, C.M., Goodstadt, L., Karn, R.C., and Ponting, C.P, Genome Research
• Evolution of the secretoglobins: A genomic and proteomic view.  
  Laukaitis, C.M. and Karn, R.C, Biological Journal of the Linnean Society
• Rapid bursts of Abp gene duplication occurred independently in diverse mammals.  
  Laukaitis, C.M., Heger, A., Blakley, T.D., Munclinger, P., Ponting, C.P., and Karn, R.C, BMC Evolutionary Biology
• A candidate Mus muculus subspecies discrimination system involving a V1R gene with different alleles fixed in M. m. domesticus and M. m. musculus.  
  Karn, R.C., Young, J.M., and Laukaitis, C.M, PLOS One
• Chemoprevention in patients with genetic risk of colorectal cancers.  
  Laukaitis, C.M., Erdman, S.H. and Gerner, E.W, Colorectal Cancer
• Join now to see all

Books/Book Chapters

• Fundamentals of Cancer Prevention 
  Chapter: Breast cancer prevention 
  Thompson, P.A., Stopeck, A. and Laukaitis, C.M.Editors: D. Alberts and L. Hess.Springer-Verlag, Berlin, GermanyEdition 3rd,2013
• Recognition of subspecies status in the evolution of incipient reinforcement on the European house mouse hybrid zone 
  Chapter: Evolution of the House Mouse 
  Laukaitis, C.M., and Karn, R.C.Editors: M. Macholan et al..Cambridge University Press, Cambridge, UK2012
• Cellular Integration of Signalling Pathways in Plant Development. NATO ASI Series. Series H: Cell Biology 
  Chapter: Intercellular and intracellular trafficking: What we can learn from Geminivirus movement 
  Lazarowitz, S.G., Ward, B.M., Sanderfoot, A.A., and Laukaitis, C.M.Springer-Verlag, Berlin, Germany1997
• Cellular Integration of Signalling Pathways in Plant Development. 
  Chapter: Intercellular and intracellular trafficking: What we can learn from Geminivirus movement 
  Lazarowitz, S. G., Ward, B. M., Sanderfoot, A. A., and Laukaitis, C. MNATO ASI Series. Series H: Cell Biology, Vol. 104, Springer, Verlag, Berlin, Germany
• Evolution of the House Mouse. 
  Chapter: Recognition of subspecies status in the evolution of incipient reinforcement on the European house mouse hybrid zone 
  Laukaitis, C.M., and Karn, R.CEditors: M. Macholán et al.Cambridge University Press, Cambridge, UK
• Join now to see all

Abstracts/Posters

• Frequent BRCA1/2 Mutations Found in Mexican & Mexican - American Women with Breast Cancer
  Chaudhury, A., Laukaitis, C.M., Mauss, C., Walsh, T., Casadei, S., Thompson, P., Lopez, AM, Daneri Navarro, A., King, M-C., American Association for Cancer Research (AACR) San Antonio Breast Cancer Symposium, San Antonio, TX, 12/1/2013
• University of Arizona Cancer Center High Risk Breast Cancer Genetics Clinic Perspective on Utilization of a Custom Next Generation Sequencing Panel
  Chaudhury, A., Mauss, C., Jeter, J.M., Laukaitis, C.M., American College of Physicians Arizona Chapter Scientific Meeting, Tucson, AZ, 11/1/2013
• QSOX1: A Desmoid Tumor Modifier Gene in FAP?
  Maher, K., Walton, S-J, Mauss, C., Clark, S., Laukaitis, C.M., American College of Physicians Arizona Chapter Scientific Meeting, Tucson, AZ, 11/1/2013
• Genomic Evaluation of Inherited Predisposition to Breast Cancer in Women from the University of Arizona Cancer Center High Risk Breast Cancer Genetics Clinic
  Chaudhury, A., Mauss, C., Jeter, J.M., Laukaitis, C.M., American Association for Cancer Research (AACR) Special Conference on Advances in Breast Cancer Research: Genetics, Biology, & Clinical Applications, San Diego, CA, 10/1/2013
• Genomic evaluation of inherited predisposition to breast cancer among women of Mexican ancestry
  C.M. Laukaitis, A. Chaudhury, C. Mauss, T. Walsh, P. Thompson, A-M Lopez, A. Daneri Navarro, M-C King, American Society of Human Genetics Annual Meeting, Boston, MA, 10/1/2013
• Seeking genes that predict desmoid formation in patients with familial adenomatous polyposis
  Laukaitis, C.M, Maher, K., Walton, S-J, Mauss, C., Clark, S., International Society for Inherited Gastrointestinal Tumors Semi-annual Meeting, Cairns, Australia, 8/1/2013
• Prevalence of Genetic Mutations in Mexican and Mexican-American Women with Breast Cancer
  Mauss, C., Thompson, P., Garcia, F., Lopez, AM, Laukaitis, C.M., American College of Medical Genetics Annual Meeting, Phoenix, AZ, 3/1/2013
• Understanding Genetic Polymorphisms and Susceptibility in High Risk Breast Cancer
  Chaudhury, A., Mauss, C., Jeter, J., Laukaitis, C.M., American College of Medical Genetics Annual Meeting, Phoenix, AZ, 3/1/2013
• Seeking genes that predict desmoid formation in patients with familial adenomatous polyposis
  Maher, K., Walton, S-J, Mauss, C., Clark, S., Laukaitis, C.M., American College of Medical Genetics Annual Meeting, Phoenix, AZ, 3/1/2013
• Expression of Androgen-binding protein genes (Abp) in lacrimal glands and tear secretions
  Chung, A., Mauss, C., Karn, R.C., Laukaitis, C.M., American College of Medical Genetics, Annual Meeting, Phoenix, AZ, 3/1/2013
• An Unusual BRCA Mutation Distribution in a High Risk Cancer Genetics Clinic
  Nelson-Moseke, A.C, Jeter, J.M., Cui, A., Roe, D.J., Chambers, S.K., and Laukaitis, C.M., American Society of Human Genetics, San Francisco, CA, 11/1/2012
• A candidate subspecies discrimination system involving a vomeronasal receptor gene with different alleles fixed in M. m. domesticus and M. m. musculus
  Karn, R.C. and Laukaitis, C.M., Beyond the Genome: The human gene count, human evolution and disease genomics, Boston, MA, 10/1/2010
• Identifying gene copy number variants associated with colorectal adenoma recurrence
  Laukaitis, C.M., Thompson, P., Martinez, M-E., and Gerner, E.W., Beyond the Genome: The human gene count, human evolution and disease genomics, Boston, MA, 10/1/2010
• Detecting Copy Number Variation in Candidate Genes for Colorectal Cancer Risk
  Laukaitis, C.M. and Thompson, P., NCI Translational Science Meeting, Vienna, VA, 11/1/2009
• Behavioral isolation in the house mouse hybrid zone
  Bimova, B., Macholan, M., Munclinger, P., Laukaitis, C.M., Karn, R. C., Tucker, P., Pialek, J., 11th International Conference on Rodent Biology "Rodens et Spatium"; 12th Congress of European Society for Evolutionary Biology, Myshkin, Russia (2005); Turin, Italy (2009), 7/1/2009
• Diverse spatial, temporal, and sexual expression of recently duplicated androgen-binding protein genes in Mus musculus
  Laukaitis, C.M., Dlouhy, S.R., Emes, R.D., Ponting, C.P., and Karn, R.C., European Society for Evolutionary Biology 10th Congress, Krakow, Poland, 8/1/2005
• The test of behavioral isolation on the mouse hybrid zone: the comparison of behavioral and molecular cline
  Bimova, B, Macholan, M., Munclinger, P., Laukaitis, C.M., Karn, R.C., Pialek J., European Society for Evolutionary Biology 10th Congress, Krakow, Poland, 8/1/2005
• The evolutionary history of a gene involved in adaptive evolution
  Karn R.C., Laukaitis C.M., Munclinger P., European Society for Evolutionary Biology 10th Congress, Krakow, Poland, 8/1/2005
• Where and when are Abp-like gene copies expressed?
  Laukaitis, C.M., Karn, R.C, American College of Physicians Annual Session, San Francisco, CA
• The evolutionary history of a gene involved in adaptive evolution.
  Karn R.C., Laukaitis C.M., Munclinger P, the European Society for Evolutionary Biology 10th Congress, Krakow, Poland
• The test of behavioral isolation on the mouse hybrid zone: the comparison of behavioral and molecular cline.
  Bímová, B., Macholán, M., Munclinger, P., Laukaitis, C.M., Karn, R.C., Pialek J, the European Society for Evolutionary Biology 10th Congress, Krakow, Poland
• Rapid bursts of Abp gene duplication occurred independently in diverse mammals.
  Laukaitis, C.M, Northwest Genetics Exchange, Vancouver, BC
• Behavioral isolation in the house mouse hybrid zone.
  Bímová, B., Macholán, M., Munclinger, P., Laukaitis, C. M., Karn, R. C., Tucker, P., Piálek, J, 11th International Conference on Rodent Biology „Rodens et Spatium, Myshkin, Russia
• Rapid bursts of Abp gene duplication in rodents and other mammals.
  Laukaitis, C.M. and Karn, R.C, Invited seminar, Masyryk University, Brno, CR
• Behavioural isolation in the house mouse hybrid zone.
  Bímová, B., Macholán, M., Munclinger, P., Laukaitis, C.M., Karn, R.C., Baird, S.J.E., Piálek, J, 12th Congress of European Society for Evolutionary Biology, Turin, Italy
• Join now to see all

Lectures

• Insensitivity to antigrowth signals 
  Oro Valley, AZ - 5/1/2014
• Selection shaped the evolution of mouse androgen-binding protein (ABP) function and promoted the duplication of Abp genes” 
  Plon, Germany - 5/1/2014
• Inherited Predisposition to Breast Cancer in Mexican and Mexican American Women 
  4/1/2014
• Inherited cancer risk in patients from the UA High-risk Cancer Genetics Clinic 
  Tucson, AZ - 2/1/2014
• Cancer BASICS 
  Tucson, AZ - 6/1/2013
• Genetic Breast Cancer Syndromes: Cancer is Preventable, but Patients are Under-recognized 
  Tucson, AZ - 4/1/2013
• Genetic Testing for the Primary Care Physician 
  Tucson, AZ - 4/1/2013
• Colorectal Cancer 
  Flagstaff, AZ - 3/1/2013
• Desmoid Tumor Genetics 
  1/1/2013
• Genetic Testing; Promise and Reality 
  11/1/2012
• The evolutionary history of three mouse pheromone gene families 
  Brno, Czech Republic - 11/1/2012
• Clinical Cancer Genetics Research 
  10/1/2012
• Ovarian cancer screening and prevention 
  Tucson, AZ - 9/1/2012
• “Cancer Basics”, “Cancer Types and Treatments” and “Cancer Prevention” 
  Seattle, WA - 7/1/2012
• Cancer basics and prevention 
  Window Rock, AZ - 6/1/2012
• Clinical Trials of Cancer Prevention 
  Window Rock, AZ - 6/1/2012
• Cancer 101 
  Tucson, AZ - 3/1/2012
• Hereditary Cancer Syndromes, Maternal and Pediatric Considerations 
  Telluride, CO - 2/1/2012
• Identifying and caring for women at high risk of breast cancer 
  Polacca, AZ - 12/1/2011
• Evidence for cancer screening and prevention; Identification of the patient at high-risk for breast cancer 
  San Xavier, AZ - 8/1/2011
• Lynch syndrome and renal cancer: Not so rare in Native Arizona 
  Chinle, AZ - 5/1/2011
• Genetics for Pulmonologists 
  Tucson, AZ - 2/1/2011
• Colon cancer in high-risk populations 
  Polacca, AZ - 12/1/2010
• Care of the patient at high risk of cancer 
  Tucson, AZ - 12/1/2010
• Genetics for the General Internist 
  Tucson, AZ (2009-2010) - 9/1/2010
• Join now to see all