ChristineHChenDO

PubMed

• Identification of NVP-TNKS656: The Use of Structure-Efficiency Relationships To Generate a Highly Potent, Selective, and Orally Active Tankyrase Inhibitor.
  Shultz, M. D.,Cheung, A. K.,Kirby, C. A.,Firestone, B.,Fan, J.,Chen, C. H.,Chen, Z.,Chin, D. N.,Dipietro, L.,Fazal, A.,Feng, Y.,Fortin, P. D.,Gould, T.,Lagu, B.,Lei, H...> ;J. Med. Chem.. 2013 Aug 22
• Optimization of the in vitro cardiac safety of hydroxamate-based histone deacetylase inhibitors.
  Shultz, M.D., Cao, X., Chen, C.H., Cho, Y.S., Davis, N.R., Eckman, J., Fan, J., Fekete, A., Firestone, B., Flynn, J., Green, J., Growney, J.D., Holmqvist, M., Hsu, M.,...> ;J Med Chem. 2011 Jul 14
• 4-(Pyrazol-4-yl)-pyrimidines as selective inhibitors of cyclin-dependent kinase 4/6.
  Cho, Y. S., Borland, M., Brain, C., Chen, C. H., Cheng, H., Chopra, R., Chung, K., Groarke, J., He, G., Hou, Y., Kim, S., Kovats, S., Lu, Y., O'Reilly, M., Shen, J., S...> ;J Med Chem. 2010 Nov 25
• Conformational refinement of hydroxamate-based histone deacetylase inhibitors and exploration of 3-piperidin-3-ylindole analogues of dacinostat (LAQ824).
  Cho, Y.S., Whitehead, L., Li, J., Chen, C.H., Jiang, L., Vögtle, M., Francotte, E., Richert, P., Wagner, T., Traebert, M., Lu, Q., Cao, X., Dumotier, B., Fejzo, J...> ;J Med Chem. 2010 Apr 8
• Fluorous Synthesis of Hydantoin-, Piperazinedione-, and Benzodiazepinedione-Fused Tricyclic and Tetracyclic Ring Systems.
  Zhang, W., Lu, Y., Chen, C.H., Curran, D.P., Geib, S.> ;European J Org Chem. 2006
• Fluorous Synthesis of Biaryl-Substituted Proline Analogs by 1,3-Dipolar Cycloaddition and Suzuki Coupling Reactions.
  Zhang, W., Chen, C.H.> ;Tetrahedron Lett. 2005-03-14
• A highly efficient microwave-assisted suzuki coupling reaction of aryl perfluorooctylsulfonates with boronic acids.
  Zhang, W., Chen, C.H., Lu, Y., Nagashima, T.> ;Org Lett. 2004 Apr 29
• FluoMar, a fluorous version of the Marshall resin for solution-phase library synthesis.
  Chen, C.H., Zhang, W.> ;Org Lett. 2003 Apr 3
• Solution-phase preparation of a 560-compound library of individual pure mappicine analogues by fluorous mixture synthesis.
  Zhang, W., Luo, Z., Chen, C.H., Curran, D.P.> ;J Am Chem Soc. 2002 Sep 4
• Effect of noncompetitive proteasome inhibition on bortezomib resistance.
  Li, X., Wood, T. E., Sprangers, R., Jansen, G., Franke, N. E., Mao, X., Wang, X., Zhang, Y., Verbrugge, S. E., Adomat, H., Li, Z. H., Trudel, S., Chen, C., Religa, T. ...> ;J Natl Cancer Inst. 2010 Jul 21
• Fluorous reagents and scavengers versus solid-supported reagents and scavengers, a reaction rate and kinetic comparison.
  Chen, C. H., Zhang, W.> ;Mol Divers. 2005
• Combination of microwave reactions with fluorous separations in the palladium-catalyzed synthesis of aryl sulfides.
  Zhang, W., Lu, Y., Chen, C. H.> ;Mol Divers. 2003
• The design, synthesis and structure-activity relationships of novel isoindoline-based histone deacetylase inhibitors.
  Shultz, M., Fan, J., Chen, C., Cho, Y. S., Davis, N., Bickford, S., Buteau, K., Cao, X., Holmqvist, M., Hsu, M., Jiang, L., Liu, G., Lu, Q., Patel, C., Suresh, J. R., ...> ;Bioorg Med Chem Lett. 2011 Aug 15
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