ChristineHuletteMD

PubMed

• Creutzfeldt-Jakob Disease Mimicking Neurosyphilis: A Complex Presentation, Histopathological Findings, and Special Precautions for Autopsy.
  Rhonda Mittenzwei, Louis R. DiBernardo, Christine M. Hulette, William T Harrison> ;The American Journal of Forensic Medicine and Pathology. 2019 Dec 1
• 38 citations
  Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry.
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,...> ;JAMA. 2019 Nov 5
• Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.
  Kunkle, B. W.,Grenier-Boley, B.,Sims, R.,Bis, J. C.,Damotte, V.,Naj, A. C.,Boland, A.,Vronskaya, M.,van der Lee, S. J.,Amlie-Wolf, A.,Bellenguez, C.,Frizatti, A.,Chour...> ;Nat. Genet.. 2019 Mar 02
• 4 citations
  Fatal Granulomatous Amebic Encephalitis in a Heart Transplant Patient: Clinical, Radiographic, and Autopsy Findings.
  William T Harrison, Bruce Lecky, Christine M. Hulette> ;Journal of Neuropathology and Experimental Neurology. 2018 Nov 1
• 21 citations
  The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target.
  Vladislav A. Petyuk, Rui Chang, Manuel Ramirez-Restrepo, Noam D. Beckmann, Marc Henrion, Paul D. Piehowski, Kuixi Zhu, Sven Wang, Jennifer Clarke, Matthew J. Huentelma...> ;Brain. 2018 Sep 1
• 1113 citations
  Analysis of shared heritability in common disorders of the brain
  Verneri Anttila, Brendan Bulik-Sullivan, Hilary K. Finucane, Raymond K. Walters, Jose Bras, Laramie E. Duncan, Valentina Escott-Price, Guido J. Falcone, Padhraig Gorml...> ;Science. 2018 Jun 22
• 5 citations
  Somatic uniparental disomy of Chromosome 16p in hemimegalencephaly.
  Nicole G. Griffin, Kenneth D. Cronin, Nicole M. Walley, Christine M. Hulette, Gerald A. Grant, Mohamad A. Mikati, Heather G. LaBreche, Catherine Rehder, Andrew S. Alle...> ;Cold Spring Harbor Molecular Case Studies. 2017 Sep 1
• 5 citations
  Cerebral Toxoplasmosis: A Case Report with Correlation of Radiographic Imaging, Surgical Pathology, and Autopsy Findings.
  William T Harrison, Christine M. Hulette> ;Academic Forensic Pathology. 2017 Sep 1
• 592 citations
  Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
  Rebecca Sims, Sven J. van der Lee, Adam C. Naj, Céline Bellenguez, Nandini Badarinarayan, Johanna Jakobsdottir, Brian W. Kunkle, Anne Boland, Rachel Raybould, Joshua C...> ;Nature Genetics. 2017 Sep 1
• 126 citations
  Transethnic genome-wide scan identifies novel Alzheimer's disease loci
  Gyungah Jun, Jaeyoon Chung, Jesse Mez, Robert Barber, Gary W. Beecham, David A. Bennett, Joseph D. Buxbaum, Goldie S. Byrd, Minerva M. Carrasquillo, Paul K. Crane, Car...> ;Alzheimer's & Dementia. 2017 Jul 1
• 19 citations
  Differential gene expression in dentate granule cells in mesial temporal lobe epilepsy with and without hippocampal sclerosis.
  Nicole G. Griffin, Yu Wang, Christine M. Hulette, Matt Halvorsen, Kenneth D. Cronin, Nicole M. Walley, Michael M. Haglund, Rodney A. Radtke, J. H. Pate Skene, Saurabh ...> ;Epilepsia. 2016 Mar 1
• 189 citations
  A novel Alzheimer disease locus located near the gene encoding tau protein
  Gyungah Jun, Carla A. Ibrahim-Verbaas, Maria Vronskaya, J-C Lambert, Jaeyoon Chung, Adam C. Naj, Brian W. Kunkle, L-S Wang, J. C. Bis, Céline Bellenguez, Denise Harold...> ;Molecular Psychiatry. 2016 Jan 1
• 26 citations
  Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals
  Mahdi Ghani, Christiane Reitz, Rong Cheng, Badri N. Vardarajan, Gyungah Jun, Christine Sato, Adam C. Naj, Ruchita Rajbhandary, Li-San Wang, Otto Valladares, Chiao-Feng...> ;JAMA Neurology. 2015 Nov 1
• 65 citations
  Postmortem diffusion MRI of the human brainstem and thalamus for deep brain stimulator electrode localization.
  Evan Calabrese, Patrick Hickey, Christine M. Hulette, Jingxian Zhang, Beth Parente, Shivanand P. Lad, G. Allan Johnson> ;Human Brain Mapping. 2015 Aug 1
• 30 citations
  Rarity of the Alzheimer disease-protective APP A673T variant in the United States
  Li-San Wang, Adam C. Naj, Robert R. Graham, Paul K. Crane, Brian W. Kunkle, Carlos Cruchaga, Josue D. Gonzalez Murcia, Lisa A. Cannon-Albright, Clinton T. Baldwin, Hen...> ;JAMA Neurology. 2015 Feb 1
• 1 citations
  Atypical lymphocytic angiitis of the optic nerve and central nervous system.
  Eleonora M. Lad, Christine M. Hulette, Alan D. Proia> ;JAMA Ophthalmology. 2014 Nov 1
• 139 citations
  Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
  Adam C. Naj, Gyungah Jun, Christiane Reitz, Brian W. Kunkle, William Perry, YoSon Park, Gary W. Beecham, Ruchita Rajbhandary, Kara L. Hamilton-Nelson, Li-San Wang, Joh...> ;JAMA Neurology. 2014 Nov 1
• 100 citations
  TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions
  Michael D. Gallagher, EunRan Suh, Murray Grossman, Lauren Elman, Leo McCluskey, John C. van Swieten, Safa Al-Sarraj, Manuela Neumann, Ellen Gelpi, Bernardino Ghetti, J...> ;Acta Neuropathologica. 2014 Jan 19
• 221 citations
  Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis
  David C. Whitcomb, Jessica LaRusch, Alyssa M. Krasinskas, Lambertus Klei, Jill P. Smith, Randall E. Brand, John P. Neoptolemos, Markus M. Lerch, Matt Tector, Bimaljit ...> ;Nature Genetics. 2012 Dec 1
• 174 citations
  Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,...> ;Human Molecular Genetics. 2012 Aug 1
• 18 citations
  The Alzheimer's associated 5' region of the SORL1 gene cis regulates SORL1 transcripts expression.
  Jeanette J. McCarthy, Sunita Saith, James R. Burke, Christine M. Hulette, Kathleen A. Welsh-Bohmer, Ornit Chiba-Falek> ;Neurobiology of Aging. 2012 Jul 1
• 1308 citations
  Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature
  Peter T. Nelson, Irina Alafuzoff, Eileen H. Bigio, Constantin Bouras, Heiko Braak, Nigel J. Cairns, Rudolph J. Castellani, Barbara J. Crain, Peter Davies, Kelly Del Tr...> ;Journal of Neuropathology and Experimental Neurology. 2012 May 1
• 8 citations
  Sudden death from diffuse leptomeningeal oligodendrogliomatosis.
  Renée M Reynolds, Elizabeth L. Boswell, Christine M. Hulette, Thomas J. Cummings, Michael M. Haglund, Thomas J. Cumm ings> ;Journal of Neurosurgery. Spine. 2011 Dec 1
• 105 citations
  Metabolomic changes in autopsy-confirmed Alzheimer's disease
  Rima Kaddurah-Daouk, Steve Rozen, Wayne R. Matson, Xianlin Han, Christine M. Hulette, James R. Burke, P. Murali Doraiswamy, Kathleen A. Welsh-Bohmer> ;Alzheimer's & Dementia. 2011 May 1
• 1426 citations
  Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
  Adam C. Naj, Gyungah Jun, Gary W. Beecham, Li-San Wang, Badri N. Vardarajan, Jacqueline L. Buros, Paul Gallins, Joseph D. Buxbaum, Gail P. Jarvik, Paul K. Crane, Eric ...> ;Nature Genetics. 2011 May 1
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Journal Articles

• The Human Brainome: Network Analysis Identifies HSPA2 as a Novel Alzheimer’s Disease Target  
  Christine M Hulette, David A Bennett, Roger L Albin, Thomas G Beach, Randall L Woltjer, Andrew P Lieberman, John F Ervin, Anzhelika Engel, Julie A Schneider, Rui Chang, Brain