Christine(Iacobuzio)Iacobuzio-DonahueMD

PubMed

• Supporting Convergence Science.
  Christine A Iacobuzio-Donahue> ;Cancer Research. 2024 Apr 1
• Metastatic site influences driver gene function in pancreatic cancer.
  Kaloyan M Tsanov, Francisco M Barriga, Yu-Jui Ho, Direna Alonso-Curbelo, Geulah Livshits, Richard P Koche, Timour Baslan, Janelle Simon, Sha Tian, Alexandra N Wuest, W...> ;Biorxiv. 2024 Mar 18
• Convergent evolution of BRCA2 reversion mutations under therapeutic pressure by PARP inhibition and platinum chemotherapy.
  Walmsley, C., Jonsson, P., Cheng, M., McBride, S., Kaeser, C., Vargas, H., Laudone, V., Taylor, B., Kappagantula, R., Baez, P., Richards, A., Noronha, A., Perera, D., ...> ;NPJ Precision Oncology. 2024 Feb 14
• 2 citations
  The nuclear factor ID3 endows macrophages with a potent anti-tumour activity.
  Deng, Z., Loyher, P., Lazarov, T., Li, L., Shen, Z., Bhinder, B., Yang, H., Zhong, Y., Alberdi, A., Massague, J., Sun, J., Benezra, R., Glass, C., Elemento, O., Geissm...> ;Nature. 2024 Feb 1
• Concordance in Oncogenic Alterations Between the Primary Tumor and Advanced Disease: Insights Into the Heterogeneity of Intrahepatic Cholangiocarcinoma.
  Harding, J., Sarah M McIntyre, William A Preston, Henry Walch, Jeremy Sharib, Ritika Kundra, Carlie Sigel, Michael E Lidsky, Peter J Allen, Michael A Morse, Wei Chen, ...> ;JCO Precision Oncology. 2024 Feb 1
• Islands of genomic stability in the face of genetically unstable metastatic cancer.
  Bowland, K., Lai, J., Skaist, A., Zhang, Y., Teh, S., Roberts, N., Thompson, E., Wheelan, S., Karchin, R., Hruban, R., Iacobuzio-Donahue, C., Eshleman, J.> ;Biorxiv. 2024 Jan 29
• A microglia clonal inflammatory disorder in Alzheimer's Disease.
  Rocio Vicario, Stamatina Fragkogianni, Leslie Weber, Tomi Lazarov, Yang Hu, Samantha Y Hayashi, Barbara P Craddock, Nicholas D Socci, Araitz Alberdi, Ann Baako, Oyku A...> ;Biorxiv. 2024 Jan 25
• ConDoR: tumor phylogeny inference with a copy-number constrained mutation loss model.
  Palash Sashittal, Haochen Zhang, Christine A Iacobuzio-Donahue, Benjamin J Raphael> ;Genome Biology. 2023 Nov 30
• Author Correction: Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression.
  Hanane Laklai, Yekaterina A Miroshnikova, Michael W Pickup, Eric A Collisson, Grace E Kim, Alex S Barrett, Ryan C Hill, Johnathon N Lakins, David D Schlaepfer, Janna K...> ;Nature Medicine. 2024 Mar 1
• Subclonal Somatic Copy-Number Alterations Emerge and Dominate in Recurrent Osteosarcoma.
  Michael D Kinnaman, Simone Zaccaria, Alvin Makohon-Moore, Brian Arnold, Max F Levine, Gunes Gundem, Juan E Arango Ossa, Dominik Glodzik, M Irene Rodríguez-Sánchez, Nan...> ;Cancer Research. 2023 Nov 15
• 1 citations
  The Ratio of Key Metabolic Transcripts Is a Predictive Biomarker of Breast Cancer Metastasis to the Lung.
  Deepti Mathur, Chen Liao, Wendy Lin, Alessandro La Ferlita, Salvatore Alaimo, Samuel Taylor, Yi Zhong, Christine Iacobuzio-Donahue, Alfredo Ferro, Joao B Xavier> ;Cancer Research. 2023 Oct 13
• 3 citations
  Tissue-specific features of the T cell repertoire after allogeneic hematopoietic cell transplantation in human and mouse.
  Susan DeWolf, Yuval Elhanati, Katherine Nichols, Nicholas R Waters, Chi L Nguyen, John B Slingerland, Natasia Rodriguez, Olga Lyudovyk, Paul A Giardina, Anastasia I Ko...> ;Science Translational Medicine. 2023 Jul 26
• A targetable pathway to eliminate TRA-1-60+/TRA-1-81+ chemoresistant cancer cells.
  Lei Tan, Xiaohua Duan, Pratyusha Mutyala, Ting Zhou, Sadaf Amin, Tuo Zhang, Brian Herbst, Gokce Askan, Tomer Itkin, Zhaoying Xiang, Fabrizio Michelassi, Michael D Lieb...> ;Journal of Molecular Cell Biology. 2023 Nov 27
• 3 citations
  Clonal evolution during metastatic spread in high-risk neuroblastoma.
  Gundem, G., Levine, M., Roberts, S., Cheung, I., Medina-Martínez, J., Feng, Y., Arango-Ossa, J., Chadoutaud, L., Rita, M., Asimomitis, G., Zhou, J., You, D., Bouvier, ...> ;Nature Genetics. 2023 Jun 1
• Back to Basics in Cancer Research: A Message from the Incoming Editor-In-Chief.
  Christine A Iacobuzio-Donahue> ;Cancer Research. 2023 May 2
• 36 citations
  STING inhibits the reactivation of dormant metastasis in lung adenocarcinoma.
  Jing Hu, Francisco J Sánchez-Rivera, Zhenghan Wang, Gabriela N Johnson, Yu-Jui Ho, Karuna Ganesh, Shigeaki Umeda, Siting Gan, Adriana M Mujal, Rebecca B Delconte, Jess...> ;Nature. 2023 Apr 1
• 2 citations
  Application of high-throughput single-nucleus DNA sequencing in pancreatic cancer.
  Haochen Zhang, Elias-Ramzey Karnoub, Shigeaki Umeda, Ronan Chaligné, Ignas Masilionis, Caitlin A McIntyre, Palash Sashittal, Akimasa Hayashi, Amanda Zucker, Katelyn Mu...> ;Nature Communications. 2023 Feb 10
• 2 citations
  The war on pancreatic cancer: progress and promise.
  Christine A Iacobuzio-Donahue> ;Nature Reviews. Gastroenterology & Hepatology. 2023 Feb 1
• Subclonal somatic copy number alterations emerge and dominate in recurrent osteosarcoma.
  Michael D Kinnaman, Simone Zaccaria, Alvin Makohon-Moore, Brian Arnold, Max Levine, Gunes Gundem, Juan E Arango Ossa, Dominik Glodzik, M Irene Rodríguez-Sánchez, Nancy...> ;Biorxiv. 2023 Jan 24
• 5 citations
  ConDoR: Tumor phylogeny inference with a copy-number constrained mutation loss model.
  Palash Sashittal, Haochen Zhang, Christine A Iacobuzio-Donahue, Benjamin J Raphael> ;Biorxiv. 2023 Jan 6
• 22 citations
  MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis.
  Francisco M Barriga, Kaloyan M Tsanov, Yu-Jui Ho, Noor Sohail, Amy Zhang, Timour Baslan, Alexandra N Wuest, Isabella Del Priore, Brigita Meškauskaitė, Geulah Livshits,...> ;Nature Cancer. 2022 Nov 1
• 8 citations
  Clinico-genomic Characterization of ATM and HRD in Pancreas Cancer: Application for Practice.
  Wungki Park, Catherine A O'Connor, Chaitanya Bandlamudi, Daniella Forman, Joanne F Chou, Shigeaki Umeda, Marsha Reyngold, Anna M Varghese, Fergus Keane, Fiyinfolu Balo...> ;Clinical Cancer Research. 2022 Nov 1
• 17 citations
  BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling.
  Lee Shaashua, Aviad Ben-Shmuel, Meirav Pevsner-Fischer, Gil Friedman, Oshrat Levi-Galibov, Subhiksha Nandakumar, Debra Barki, Reinat Nevo, Lauren E Brown, Wenhan Zhang...> ;Nature Communications. 2022 Oct 31
• 4 citations
  Systematic Comparison of Pancreatic Ductal Adenocarcinoma Models Identifies a Conserved Highly Plastic Basal Cell State.
  Kenneth L Pitter, Olivera Grbovic-Huezo, Simon Joost, Anupriya Singhal, Melissa Blum, Katherine Wu, Matilda Holm, Alexander Ferrena, Arjun Bhutkar, Anna Hudson, Nicola...> ;Cancer Research. 2022 Oct 4
• 72 citations
  Ordered and deterministic cancer genome evolution after p53 loss.
  Timour Baslan, John P Morris 4th, Zhen Zhao, Jose Reyes, Yu-Jui Ho, Kaloyan M Tsanov, Jonathan Bermeo, Sha Tian, Sean Zhang, Gokce Askan, Aslihan Yavas, Nicolas Lecomt...> ;Nature. 2022 Aug 1
• Join now to see all