ChristopherC.LaiMD

PubMed

• 23 citations
  Mono-anionic phosphopeptides produced by unexpected histidine alkylation exhibit high plk1 polo-box domain-binding affinities and enhanced antiproliferative effects in...
  Wen-Jian Qian, Jung-Eun Park, Daniel Lim, Christopher C. Lai, James A. Kelley, Suk-Youl Park, Ki Won Lee, Michael B. Yaffe, Kyung S. Lee, Terrence R. Burke> ;Biopolymers. 2014 Nov 1
• 3 citations
  Design and synthesis of Fmoc-Thr[PO(OH)(OPOM)] for the preparation of peptide prodrugs containing phosphothreonine in fully protected form.
  Wen-Jian Qian, Christopher C. Lai, James A. Kelley, Terrence R. Burke> ;Chemistry & Biodiversity. 2014 May 1
• 17 citations
  Synthesis and biological evaluation of novel dihydro-aryl/alkylsulfanyl-cyclohexylmethyl-oxopyrimidines (S-DACOs) as high active anti-HIV agents.
  Yan-Ping He, Jin Long, Shui-Shuan Zhang, Cong Li, Christopher C. Lai, Chun-Sheng Zhang, Da-Xiong Li, De-Hua Zhang, Hua Wang, Qing-Qing Cai, Yong-Tang Zheng> ;Bioorganic & Medicinal Chemistry Letters. 2011 Jan 15
• 32 citations
  Comparison of baseline characteristics, management and outcome of patients with non-ST-segment elevation acute coronary syndrome in versus not in clinical trials.
  Adam B. Hutchinson-Jaffe, Shaun G. Goodman, Raymond T. Yan, Ron Wald, Basem Elbarouni, Barry Rose, Kim A. Eagle, Christopher C. Lai, Carolyn Baer, Anatoly Langer, Andr...> ;The American Journal of Cardiology. 2010 Nov 15
• 4 citations
  North- and south-bicyclo[3.1.0]hexene nucleosides: the effect of ring planarity on anti-HIV activity.
  Pamela Russ, Maria J. Gonzalez-Moa, B. Christie Vu, Dina M. Sigano, James A. Kelley, Christopher C. Lai, Jeffrey R. Deschamps, Stephen H. Hughes, Victor E. Marquez> ;Chemmedchem. 2009 Aug 3
• 23 citations
  A novel side-bridged hybrid phosphonate/acetate pendant cyclam: synthesis, characterization, and 64Cu small animal PET imaging.
  C. Andrew Boswell, Celeste A. S. Regino, Kwamena E. Baidoo, Karen J. Wong, Diane E. Milenic, James A. Kelley, Christopher C. Lai, Martin W. Brechbiel> ;Bioorganic & Medicinal Chemistry. 2009 Jan 15
• 35 citations
  Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activities.
  , , , , , , , , , , , , , , , , , , , , , , , , > ;Journal of Medicinal Chemistry. 2008 Sep 11
• 46 citations
  Synthesis of a cross-bridged cyclam derivative for peptide conjugation and 64Cu radiolabeling.
  C. Andrew Boswell, Celeste A. S. Regino, Kwamena E. Baidoo, Karen J. Wong, Ambika Bumb, Heng Xu, Diane E. Milenic, James A. Kelley, Christopher C. Lai, Martin W. Brech...> ;Bioconjugate Chemistry. 2008 Jul 3
• 18 citations
  Conformationally Constrained Analogues of Diacylglycerol (DAG). 27. Modulation of Membrane Translocation of Protein Kinase C (PKC) Isozymes α and δ by Diacylglycerol L...
  Krishnan Malolanarasimhan, Noemi Kedei, Dina M. Sigano, James A. Kelley, Christopher C. Lai, Nancy E. Lewin, Robert J. Surawski, Vladimir A. Pavlyukovets, Susan H. Gar...> ;Journal of Medicinal Chemistry. 2007 Feb 7
• 7 citations
  Design and concise synthesis of fully protected analogues of l-gamma-carboxyglutamic acid.
  Sheng Jiang, Peng Li, Christopher C. Lai, James A. Kelley, Peter P. Roller> ;The Journal of Organic Chemistry. 2006 Sep 15
• 5 citations
  Synthesis and biological study of a flavone acetic acid analogue containing an azido reporting group designed as a multifunctional binding site probe.
  Krishnan Malolanarasimhan, Christopher C. Lai, James A. Kelley, Lynn Iaccarino, Della Reynolds, Howard A. Young, Victor E. Marquez> ;Bioorganic & Medicinal Chemistry. 2005 Apr 15
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