ChristopherJKennedyMD

PubMed

• 13 citations
  Fatty acid mimetic PBI-4547 restores metabolic homeostasis via GPR84 in mice with non-alcoholic fatty liver disease
  Jean-Christophe Simard, Jean-Francois Thibodeau, Martin Leduc, Mikaël Tremblay, Alexandre Laverdure, François Sarra-Bournet, William Gagnon, Jugurtha Ouboudinar, Liett...> ;Scientific Reports. 2020 Jul 29
• 56 citations
  Vascular contributions to 16p11.2 deletion autism syndrome modeled in mice
  Julie Ouellette, Xavier Toussay, Cesar H. Comin, Luciano da Fontoura Costa, Mirabelle Ho, María Lacalle-Aurioles, Moises Freitas-Andrade, Qing Yan Liu, Sonia Leclerc, ...> ;Nature Neuroscience. 2020 Jul 13
• 36 citations
  Nox (NADPH Oxidase) 1, Nox4, and Nox5 Promote Vascular Permeability and Neovascularization in Retinopathy
  Devy Deliyanti, Saeed F. Alrashdi, Rhian M. Touyz, Chris R. J. Kennedy, Jay C. Jha, Mark E. Cooper, Karin Jandeleit-Dahm, Jennifer L. Wilkinson-Berka> ;Hypertension. 2020 Mar 2
• 10 citations
  Prostaglandin E2 receptor EP1 (PGE2/EP1) deletion promotes glomerular podocyte and endothelial cell injury in hypertensive TTRhRen mice.
  Rania Nasrallah, Joseph Zimpelmann, Susan J. Robertson, Jamie Ghossein, Jean-Francois Thibodeau, Christopher R.J. Kennedy, Alex Gutsol, Fengxia Xiao, Dylan Burger, Kev...> ;Laboratory Investigation; a Journal of Technical Methods and Pathology. 2020 Mar 1
• 6 citations
  Beta-Cell-Specific Expression of Nicotinamide Adenine Dinucleotide Phosphate Oxidase 5 Aggravates High-Fat Diet-Induced Impairment of Islet Insulin Secretion in Mice.
  Karim Bouzakri, Christelle Veyrat-Durebex, Chet E. Holterman, Caroline Arous, Charlotte Barbieux, Domenico Bosco, Jordi Altirriba, Mohamed Alibashe, Benjamin B. Tourni...> ;Antioxidants & Redox Signaling. 2020 Feb 13
• 6 citations
  PBI-4050 via GPR40 activation improves adenine-induced kidney injury in mice.
  Jean-Francois Thibodeau, Jean-Christophe Simard, Chet E. Holterman, Amélie Blais, Marie-Pier Cloutier, Thalia Medeiros, Martin Leduc, Brigitte Grouix, Francois A. Lebl...> ;Clinical Science. 2019 Jul 31
• 26 citations
  Endothelial or vascular smooth muscle cell-specific expression of human NOX5 exacerbates renal inflammation, fibrosis and albuminuria in the Akita mouse
  Jay C. Jha, Aozhi Dai, Chet E. Holterman, Mark E. Cooper, Rhian M. Touyz, Chris R. J. Kennedy, Karin Jandeleit-Dahm> ;Diabetologia. 2019 Jun 20
• 3 citations
  A novel method for comparison of arterial remodeling in hypertension: Quantification of arterial trees and recognition of remodeling patterns on histological sections.
  Alex Gutsol, Paula Blanco, Svetlana I. Samokhina, S. A. Afanasiev, Christopher R.J. Kennedy, Sergey V. Popov, Kevin D. Burns> ;Plos One. 2019 May 21
• 18 citations
  Podocyte NADPH Oxidase 5 Promotes Renal Inflammation Regulated by the Toll-Like Receptor Pathway.
  Chet E. Holterman, Naomi C. Boisvert, Jean-Francois Thibodeau, Eldjonai Kamto, Melica Novakovic, Khaled S. Abd-Elrahman, Stephen S. G. Ferguson, Christopher R.J. Kennedy> ;Antioxidants & Redox Signaling. 2019 Apr 4
• Use of Cognitive Task Analysis to Understand Decision-making for Management of Blunt Abdominal Trauma in Children.
  Tania Ahluwalia, Serkan Toy, Chris R. J. Kennedy> ;Cureus. 2019 Feb 19
• 9 citations
  Proteostasis as a therapeutic target in glomerular injury associated with mutant α-actinin-4.
  Albert Yee, Joan Papillon, Julie Guillemette, Daniel R. Kaufman, Chris R. J. Kennedy, Andrey V. Cybulsky> ;American Journal of Physiology. Renal Physiology. 2018 Oct 1
• 3 citations
  Ubiquitin COOH-terminal hydrolase L1 deletion is associated with urinary α-klotho deficiency and perturbed phosphate homeostasis.
  Naomi C. Boisvert, Chet E. Holterman, Alexey Gutsol, Josée Coulombe, Wanling Pan, R. Todd Alexander, Douglas A. Gray, Chris R. J. Kennedy> ;American Journal of Physiology. Renal Physiology. 2018 Aug 1
• 8 citations
  GRK2 knockdown in mice exacerbates kidney injury and alters renal mechanisms of blood pressure regulation.
  Elena Tutunea-Fatan, Khaled S. Abd-Elrahman, Jean-Francois Thibodeau, Chet E. Holterman, Brian J. Holleran, Richard Leduc, Christopher R.J. Kennedy, Robert Gros, Steph...> ;Scientific Reports. 2018 Jul 30
• 3 citations
  Hyperfiltration in ubiquitin C-terminal hydrolase L1-deleted mice.
  Naomi C. Boisvert, Chet E. Holterman, Jean-Francois Thibodeau, Rania Nasrallah, Eldjonai Kamto, Cesar H. Comin, Luciano da Fontoura Costa, Anthony Carter, Richard L. H...> ;Clinical Science. 2018 Jul 18
• 41 citations
  NADPH Oxidase 5 Is a Pro-Contractile Nox Isoform and a Point of Cross-Talk for Calcium and Redox Signaling-Implications in Vascular Function.
  Augusto C. Montezano, Livia L Camargo, Patrik Persson, Francisco J. Rios, Adam Harvey, Aikaterini Anagnostopoulou, Roberto Palacios, Ana Caroline P. Gandara, Rheure Al...> ;Journal of the American Heart Association. 2018 Jun 15
• 87 citations
  A Newly Discovered Antifibrotic Pathway Regulated by Two Fatty Acid Receptors: GPR40 and GPR84.
  Lyne Gagnon, Martin Leduc, Jean-Francois Thibodeau, Ming-Zhi Zhang, Brigitte Grouix, François Sarra-Bournet, William Gagnon, Kathy Hince, Mikaël Tremblay, Lilianne Gee...> ;The American Journal of Pathology. 2018 May 1
• 20 citations
  PGE 2 EP 1 receptor inhibits vasopressin-dependent water reabsorption and sodium transport in mouse collecting duct
  Rania Nasrallah, Joseph Zimpelmann, David Eckert, Jamie Ghossein, Sean D. Geddes, Jean-Claude Béïque, Jean-Francois Thibodeau, Christopher R.J. Kennedy, Kevin D. Burns...> ;Laboratory Investigation; a Journal of Technical Methods and Pathology. 2018 Mar 1
• 60 citations
  Podocyte-derived microparticles promote proximal tubule fibrotic signaling via p38 MAPK and CD36.
  Mercedes N. Munkonda, Shareef Akbari, Chloé Landry, Suzy Sun, Fengxia Xiao, Maddison Turner, Chet E. Holterman, Rania Nasrallah, Richard L. Hébert, Chris R. J. Kennedy...> ;Journal of Extracellular Vesicles. 2018 Feb 2
• 7 citations
  Transforming growth factor-β1 and phosphatases modulate COX-2 protein expression and TAU phosphorylation in cultured immortalized podocytes.
  Maya Abdallah, Chris R. J. Kennedy, Joseph S. Stephan, Pamela Abou Khalil, Mohammad Mroueh, Assaad A. Eid, Wissam H. Faour> ;Inflammation Research. 2018 Feb 1
• 101 citations
  NADPH Oxidase Nox5 Accelerates Renal Injury in Diabetic Nephropathy
  Jay C. Jha, Claudine Banal, Jun Okabe, Stephen P. Gray, Thushan S. Hettige, Bryna S.M. Chow, Vicki Thallas-Bonke, Lisanne C. de Vos, Chet E. Holterman, Melinda T. Coug...> ;Diabetes. 2017 Oct 1
• 54 citations
  Assessment of urinary microparticles in normotensive patients with type 1 diabetes.
  Yuliya Lytvyn, Fengxia Xiao, Chris R. J. Kennedy, Bruce A. Perkins, Heather N. Reich, James W. Scholey, David Z.I. Cherney, Dylan Burger> ;Diabetologia. 2017 Mar 1
• 41 citations
  Effects of diluted bitumen exposure on juvenile sockeye salmon: From cells to performance
  Sarah L. Alderman, Feng Lin, Anthony P. Farrell, Christopher J. Kennedy, Todd E. Gillis> ;Environmental Toxicology and Chemistry. 2017 Feb 1
• 12 citations
  Vascular Smooth Muscle-Specific EP4 Receptor Deletion in Mice Exacerbates Angiotensin II-Induced Renal Injury.
  Jean-Francois Thibodeau, Chet E. Holterman, Ying He, Anthony Carter, Gregory O. Cron, Naomi C. Boisvert, Khaled S. Abd-Elrahman, Karolynn J Hsu, Stephen S. G. Ferguson...> ;Antioxidants & Redox Signaling. 2016 Oct 20
• 13 citations
  Time course of hepatic gene expression and plasma vitellogenin protein concentrations in estrone-exposed juvenile rainbow trout (Oncorhynchus mykiss).
  Heather L. Osachoff, Lorraine L.Y. Brown, Leena Tirrul, Graham van Aggelen, Fiona S. L. Brinkman, Christopher J. Kennedy> ;Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics. 2016 Sep 1
• 4 citations
  The Pediatric Subspecialty Match: Past, Present, and Future.
  Markus S. Renno, Annabelle de St Maurice, Chris R. J. Kennedy, Richard Mink> ;The Journal of Pediatrics. 2016 Jun 1
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