ChristopherMarianiMDPhD

PubMed

• 200 citations
  Fumarate and Succinate Regulate Expression of Hypoxia-Inducible Genes via TET Enzymes
  Tuomas Laukka, Christopher J. Mariani, Tuukka Ihantola, John Z. Cao, Juho Hokkanen, William G. Kaelin, Lucy A. Godley, Peppi Koivunen> ;The Journal of Biological Chemistry. 2016 Feb 19
• 10 citations
  TET-catalyzed 5-hydroxymethylcytosine regulates gene expression in differentiating colonocytes and colon cancer.
  Christopher G Chapman, Christopher J Mariani, Feng Wu, Katherine Meckel, Fatma Butun, Alice Chuang, Jozef Madzo, John H Kwon, Lucy A Godley, Bissonnette, M.> ;Scientific Reports. 2015 Dec 3
• Germline ETV6 mutations in familial thrombocytopenia and hematologic malignancy.
  Zhang, M. Y.,Churpek, J. E.,Keel, S. B.,Walsh, T.,Lee, M. K.,Loeb, K. R.,Gulsuner, S.,Pritchard, C. C.,Sanchez-Bonilla, M.,Delrow, J. J.,Basom, R. S.,Forouhar, M.,Gyur...> ;Nat. Genet.. 2015 Jan 13
• New themes in the biological functions of 5-methylcytosine and 5-hydroxymethylcytosine.
  Moen, E. L.,Mariani, C. J.,Zullow, H.,Jeff-Eke, M.,Litwin, E.,Nikitas, J. N.,Godley, L. A.> ;Immunol. Rev.. 2014 Dec 17
• TET1-Mediated Hydroxymethylation Facilitates Hypoxic Gene Induction in Neuroblastoma.
  Mariani, C. J.,Vasanthakumar, A.,Madzo, J.,Yesilkanal, A.,Bhagat, T.,Yu, Y.,Bhattacharyya, S.,Wenger, R. H.,Cohn, S. L.,Nanduri, J.,Verma, A.,Prabhakar, N. R.,Godley, ...> ;Cell Rep. 2014 May 20
• 33 citations
  Alterations of 5-hydroxymethylcytosine in human cancers.
  Christopher J. Mariani, Jozef Madzo, Erika L. Moen, Ali Ekrem Yesilkanal, Lucy A. Godley> ;Cancers. 2013 Jun 25
• Thiadiazole carbamates: potent inhibitors of lysosomal acid lipase and potential Niemann-Pick type C disease therapeutics.
  Rosenbaum, A. I., Cosner, C. C., Mariani, C. J., Maxfield, F. R., Wiest, O., Helquist, P.> ;J Med Chem. 2010 Jul 22
• Investigation of N-aryl-3-alkylidenepyrrolinones as potential Niemann-Pick type C disease therapeutics.
  Cosner, C. C., Markiewicz, J. T., Bourbon, P., Mariani, C. J., Wiest, O., Rujoi, M., Rosenbaum, A. I., Huang, A. Y., Maxfield, F. R., Helquist, P.> ;J Med Chem. 2009 Sep 24
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Journal Articles

• Alterations of 5-Hydroxymethylcytosine in Human Cancers  
  Mariani, CJ; Madzo, J; Moen, EL; Yesilkanal, A; Godley LA, Cancers, 6/25/2013

Books/Book Chapters

• Cancer Biology Review: A Case-Based Approach 
  Chapter: Chapter 3: Chromosomal Dynamics and Stability 
  Mariani, CJ; Moen, EL; Macrae, T; Daunov, M; Ostler, KR; Godley, LAEditors: Stadler, W.Demos Medical