ChristopherTRitchlinMD

Rheumatology • Rochester, NY

Rheumatoid Arthritis & Related, Vasculitis

Professor, Medicine, University of Rochester School of Medicine & Dentistry

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Office
400 Red Creek Dr
Suite 240
Rochester, NY 14623
Phone+1 585-486-0901

Fax+1 585-340-5399
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Education & Training

NYU Grossman School of MedicineFellowship, Rheumatology, 1986 - 1989
Icahn School of Medicine at Mount Sinai/Mount Sinai HospitalResidency, Internal Medicine, 1983 - 1985
Albany Medical CenterInternship, Internal Medicine, 1982 - 1983
Albany Medical CollegeClass of 1982

Certifications & Licensure

NY State Medical License 1984 - 2026
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Rheumatology

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012
Fellow (FACR) American College of Rheumatology

Clinical Trials

Centocor Microarray Study of Patients Start of enrollment: 2007 Mar 01
Completed
Phase 4
Draining PLN and Synovial Inflammation in RA Knee Joints Pre and Post Anti-TNF or B Cell Depletion Therapy Start of enrollment: 2009 Jul 01
Terminated
Certolizumab and Lower Extremity Lymph Flow in Rheumatoid Arthritis (RA) Start of enrollment: 2010 Oct 01
Completed
National Psoriasis Foundation - Dendritic Cell-Specific Transmembrane Protein (DC-Stamp) Biomarker Study Start of enrollment: 2010 Jun 01
Completed
NIR Fluorescence Imaging of Lymphatic Transport Using ICG Start of enrollment: 2015 Dec 08
Completed
Phase 1
Teriparatide as a Chondroregenerative Therapy in OA Start of enrollment: 2017 May 01
Completed
Phase 2
Multi-Center PAMPA Study Start of enrollment: 2022 Feb 16
Recruiting
Phase 4
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

Association between enthesitis/dactylitis resolution and patient-reported outcomes in guselkumab-treated patients with psoriatic arthritis.
Proton Rahman, Iain B McInnes, Atul Deodhar, Georg Schett, Phillip J Mease, May Shawi, Daniel J Cua, Jonathan P Sherlock, Alexa P Kollmeier, Xie L Xu, Shihong Sheng, C...> ;Clinical Rheumatology. 2024 May 1
Bimekizumab treatment in patients with active psoriatic arthritis and prior inadequate response to tumour necrosis factor inhibitors: 52-week safety and efficacy from ...
Laura C Coates, Robert Landewé, Iain B McInnes, Philip J Mease, Christopher T Ritchlin, Yoshiya Tanaka, Akihiko Asahina, Frank Behrens, Dafna D Gladman, Laure Gossec, ...> ;RMD Open. 2024 Feb 22
Association of the clinical components in the distal interphalangeal joint synovio-entheseal complex and subsequent response to ixekizumab or adalimumab in psoriatic a...
Dennis McGonagle, Arthur Kavanaugh, Iain B McInnes, Lars Erik Kristensen, Joseph F Merola, Bruce Strober, Rebecca Bolce, Jeffrey Lisse, Jennifer Pustizzi, Christophe S...> ;Rheumatology. 2024 Feb 10
Vaccination recommendations for adults receiving biologics and oral therapies for psoriasis and psoriatic arthritis: Delphi consensus from the medical board of the Nat...
Chat, V., Ellebrecht, C., Kingston, P., Gondo, G., Bell, S., Cordoro, K., Desai, S., Duffin, K., Feldman, S., Garg, A., Gelfand, J., Gladman, D., Green, L., Gudjonsson...> ;Journal of the American Academy of Dermatology. 2024 Feb 7
1 citations
IL-23 induces CLEC5AIL-17Aneutrophils and elicit skin inflammation associated with psoriatic arthritis.
Hiroki Furuya, Cuong Thach Nguyen, Trevor Chan, Alina I Marusina, Alexander A Merleev, Maria de la Luz Garcia-Hernandez, Shie-Liang Hsieh, George C Tsokos, Christopher...> ;Journal of Autoimmunity. 2024 Feb 1
6 citations
Bimekizumab treatment in biologic DMARD-naïve patients with active psoriatic arthritis: 52-week efficacy and safety results from the phase III, randomised, placebo-con...
Christopher T Ritchlin, Laura C Coates, Iain B McInnes, Philip J Mease, Joseph F Merola, Yoshiya Tanaka, Akihiko Asahina, Laure Gossec, Alice B Gottlieb, Richard B War...> ;Annals of the Rheumatic Diseases. 2023 Nov 1
1 citations
Derivation of a Multivariable Psoriatic Arthritis Risk Estimation Tool (PRESTO): A Step Towards Prevention.
Lihi Eder, Ker-Ai Lee, Vinod Chandran, Jessica Widdifield, Aaron M Drucker, Christopher Ritchlin, Cheryl F Rosen, Richard J Cook, Dafna D Gladman> ;Arthritis & Rheumatology. 2023 Aug 9
Guselkumab Modulates Differentially Expressed Genes in Blood of Patients With Psoriatic Arthritis: Results from Two Phase 3, Randomized, Placebo-Controlled Trials.
Stefan Siebert, Kristen M Sweet, Christopher T Ritchlin, Elizabeth C Hsia, Alexa P Kollmeier, Xie L Xu, Loqmane Seridi, Qingxuan Song, Sheng Gao, Warner Chen, Michelle...> ;ACR Open Rheumatology. 2023 Sep 1
10 citations
Spatial transcriptomics stratifies psoriatic disease severity by emergent cellular ecosystems.
Rochelle L Castillo, Ikjot Sidhu, Igor Dolgalev, Tinyi Chu, Aleksandr Prystupa, Ipsita Subudhi, Di Yan, Piotr Konieczny, Brandon Hsieh, Rebecca H Haberman, Shanmugapri...> ;Science Immunology. 2023 Jun 8
1 citations
Expert Perspective: Management of the Psoriatic Arthritis Patient After Failure of One Tumor Necrosis Factor Inhibitor.
Ying-Ying Leung, Arthur Kavanaugh, Christopher T Ritchlin> ;Arthritis & Rheumatology. 2023 Aug 1
Guselkumab, a Selective Interleukin-23 p19 Subunit Inhibitor, Resolves Dactylitis in Patients With Active Psoriatic Arthritis: Pooled Results Through Week 52 From Two ...
Dennis McGonagle, Iain B McInnes, Atul Deodhar, Georg Schett, May Shawi, Soumya D Chakravarty, Alexa P Kollmeier, Xie L Xu, Shihong Sheng, Stephen Xu, Christopher T Ri...> ;ACR Open Rheumatology. 2023 Apr 1
1 citations
Near-Infrared Imaging of Indocyanine Green Identifies Novel Routes of Lymphatic Drainage from Metacarpophalangeal Joints in Healthy Human Hands.
H Mark Kenney, Gregory Dieudonne, Seonghwan Yee, Jeffrey H Maki, Ronald W Wood, Edward M Schwarz, Christopher T Ritchlin, Homaira Rahimi> ;Lymphatic Research and Biology. 2023 Aug 1
1 citations
Multidomain Efficacy and Safety of Guselkumab Through 1 Year in Patients With Active Psoriatic Arthritis With and Without Prior Tumor Necrosis Factor Inhibitor Experie...
Christopher T Ritchlin, Atul Deodhar, Wolf-Henning Boehncke, Enrique R Soriano, Alexa P Kollmeier, Xie L Xu, Federico Zazzetti, May Shawi, Yusang Jiang, Shihong Sheng,...> ;ACR Open Rheumatology. 2023 Mar 1
2 citations
Implementation of automated behavior metrics to evaluate voluntary wheel running effects on inflammatory-erosive arthritis and interstitial lung disease in TNF-Tg mice.
H Mark Kenney, Ronald W Wood, Gabriel Ramirez, Richard D Bell, Kiana L Chen, Lindsay Schnur, Homaira Rahimi, Benjamin D Korman, Lianping Xing, Christopher T Ritchlin, ...> ;Arthritis Research & Therapy. 2023 Feb 2
3 citations
The Enigmas of Lymphatic Muscle Cells: Where Do They Come From, How Are They Maintained, and Can They Regenerate?
H Mark Kenney, Yue Peng, Karen L de Mesy Bentley, Lianping Xing, Christopher T Ritchlin, Edward M Schwarz> ;Current Rheumatology Reviews. 2023 Jun 5
2 citations
The effect of guselkumab on inhibiting radiographic progression in patients with active psoriatic arthritis: study protocol for APEX, a Phase 3b, multicenter, randomiz...
Christopher T Ritchlin, Laura C Coates, Philip J Mease, Désirée van der Heijde, Jiao Song, Yusang Jiang, May Shawi, Alexa P Kollmeier, Proton Rahman> ;Trials. 2023 Jan 10
42 citations
Bimekizumab in patients with active psoriatic arthritis and previous inadequate response or intolerance to tumour necrosis factor-α inhibitors: a randomised, double-bl...
Merola, J. F., Merola, J. F., Merola, J. F., Joseph F Merola, Robert Landewé, Iain B McInnes, Philip J Mease, Christopher T Ritchlin, Yoshiya Tanaka, Akihiko Asahina, ...> ;Lancet. 2023 Jan 7
1 citations
Home Phototherapy Improves Access to Dermatologic Care: A Novel Stakeholder Alliance to Facilitate Its Implementation.
Fatima Bawany, Julie Ryan Wolff, Christopher T Ritchlin, Francisco Tausk> ;Clinical, Cosmetic and Investigational Dermatology. 2023 Jan 1
Distinct mast cell subpopulations within and around lymphatic vessels regulate lymph flow and progression of inflammatory-erosive arthritis in TNF-transgenic mice.
Kenney, M., Yue Peng, H Mark Kenney, Karen L de Mesy Bentley, Lianping Xing, Christopher T Ritchlin, Edward M Schwarz> ;Frontiers in Immunology. 2023 Jan 1
Multi-omics analysis identifies IgG2b class-switching with ALCAM-CD6 co-stimulation in joint-draining lymph nodes during advanced inflammatory-erosive arthritis.
Kenney, M., Kenney, M., H Mark Kenney, Javier Rangel-Moreno, Yue Peng, Kiana L Chen, Jennifer Bruno, Abdul Embong, Elizabeth Pritchett, Jeffrey I Fox, Enrique Becerril...> ;Frontiers in Immunology. 2023 Jan 1
Quantification of pre-existing radiographic damage and its relationship with joint activity and long-term clinical outcomes with secukinumab therapy in patients with p...
Philip Mease, Désirée van der Heijde, Bruce Kirkham, Georg Schett, Ana-Maria Orbai, Christopher Ritchlin, Luminita Pricop, David A James, Xuan Zhu, Gregory Ligozio, Me...> ;Arthritis Research & Therapy. 2022 Dec 28
44 citations
Bimekizumab in patients with psoriatic arthritis, naive to biologic treatment: a randomised, double-blind, placebo-controlled, phase 3 trial (BE OPTIMAL).
Iain B McInnes, Akihiko Asahina, Laura C Coates, Robert Landewé, Christopher T Ritchlin, Yoshiya Tanaka, Laure Gossec, Alice B Gottlieb, Richard B Warren, Barbara Ink,...> ;Lancet. 2023 Jan 7
11 citations
Thy-1 plays a pathogenic role and is a potential biomarker for skin fibrosis in scleroderma.
Roberta G Marangoni, Poulami Datta, Ananta Paine, Stacey Duemmel, Marc Nuzzo, Laura Sherwood, John Varga, Christopher Ritchlin, Benjamin D Korman> ;JCI Insight. 2022 Oct 10
5 citations
Comparative effectiveness of guselkumab in psoriatic arthritis: updates to a systematic literature review and network meta-analysis.
Philip J Mease, Iain B McInnes, Lai-Shan Tam, Raji Rajalingam, Steve Peterson, Fareen Hassan, Soumya D Chakravarty, Christine Contré, Alison Armstrong, Wolf-Henning Bo...> ;Rheumatology. 2023 Apr 3
10 citations
Upadacitinib as monotherapy and in combination with non-biologic disease-modifying antirheumatic drugs for psoriatic arthritis.
Peter Nash, Pascal Richette, Laure Gossec, Antonio Marchesoni, Christopher Ritchlin, Koji Kato, Erin L McDearmon-Blondell, Elizabeth Lesser, Reva McCaskill, Dai Feng, ...> ;Rheumatology. 2022 Aug 3
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Journal Articles

Psoriasis: Psychosomatic, Somatopsychic, or Both?
Chase W Kwon, Francisco Tausk, Christopher Ritchlin, ScienceDirect

Lectures

American College of Rheumatology (ACR): Winter Rheumatology Symposium
American College of Rheumatology(ACR), Snowmass, Colorado - 1/26/2013

Press Mentions

Good News on GuselkumabMay 26th, 2023
Can Psoriasis Care Limit CVD, PsA, and Depression?April 25th, 2023
ACR Study: Belimumab Improves CLE TooNovember 11th, 2022
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Grant Support

Role Of B Cells In Synovial Inflammation &Ln Remodeling In RA ArthritisNational Institute Of Allergy And Infectious Diseases2010–2011
Osteoclastic Bone Resorption In Psoriatic ArthritisNational Institute Of Arthritis And Musculoskeletal And Skin Diseases2001–2003