ChristopherTiptonMD

PubMed

• 44 citations
  Understanding B-cell activation and autoantibody repertoire selection in systemic lupus erythematosus: A B-cell immunomics approach.
  Christopher M. Tipton, Jennifer Hom, Christopher F. Fucile, Alexander F. Rosenberg, Iñaki Sanz> ;Immunological Reviews. 2018 Jul 1
• Rapid expansion of preexisting nonleukemic hematopoietic clones frequently follows induction therapy for de novo AML.
  Wong, T. N.,Miller, C. A.,Klco, J. M.,Petti, A.,Demeter, R.,Helton, N. M.,Li, T.,Fulton, R. S.,Heath, S. E.,Mardis, E. R.,Westervelt, P.,DiPersio, J. F.,Walter, M. J.,...> ;Blood. 2015 Dec 04
• Meta-Analysis of the Efficacy and Safety of Prazosin versus Placebo for the Treatment of Nightmares and Sleep Disturbances in Adults with Post-Traumatic Stress Disorder.
  George, K. C.,Kebejian, L.,Ruth, L. J.,Miller, C. W.,Himelhoch, S.> ;J Trauma Dissociation. 2016 Feb 03
• 336 citations
  Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus
  Christopher M. Tipton, Christopher F. Fucile, Jaime Darce, Asiya Seema Chida, Travis Ichikawa, Ivan V. Gregoretti, Sandra M Schieferl, Jennifer Hom, Scott A. Jenks, Ro...> ;Nature Immunology. 2015 Jul 1
• Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial.
  Holcomb, J. B.,Tilley, B. C.,Baraniuk, S.,Fox, E. E.,Wade, C. E.,Podbielski, J. M.,del Junco, D. J.,Brasel, K. J.,Bulger, E. M.,Callcut, R. A.,Cohen, M. J.,Cotton, B. ...> ;JAMA. 2015 Feb 04
• Ras-mediated modulation of pyruvate dehydrogenase activity regulates mitochondrial reserve capacity and contributes to glioblastoma tumorigenesis.
  Prabhu, A.,Sarcar, B.,Miller, C. R.,Kim, S. H.,Nakano, I.,Forsyth, P.,Chinnaiyan, P.> ;Neuro-oncology. 2015 Feb 26
• Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells.
  Spencer, D. H.,Young, M. A.,Lamprecht, T. L.,Helton, N. M.,Fulton, R.,O'Laughlin, M.,Fronick, C.,Magrini, V.,Demeter, R. T.,Miller, C. A.,Klco, J. M.,Wilson, R. K.,Ley...> ;Leukemia. 2015 Jan 21
• Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.
  Wong, T. N.,Ramsingh, G.,Young, A. L.,Miller, C. A.,Touma, W.,Welch, J. S.,Lamprecht, T. L.,Shen, D.,Hundal, J.,Fulton, R. S.,Heath, S.,Baty, J. D.,Klco, J. M.,Ding, L...> ;Nature. 2014 Dec 10
• Enforced differentiation of Dnmt3a-null bone marrow leads to failure with c-Kit mutations driving leukemic transformation.
  Celik, H.,Mallaney, C.,Kothari, A.,Ostrander, E. L.,Eultgen, E.,Martens, A.,Miller, C. A.,Hundal, J.,Klco, J. M.,Challen, G. A.> ;Blood. 2014 Nov 25
• Age-related mutations associated with clonal hematopoietic expansion and malignancies.
  Xie, M.,Lu, C.,Wang, J.,McLellan, M. D.,Johnson, K. J.,Wendl, M. C.,McMichael, J. F.,Schmidt, H. K.,Yellapantula, V.,Miller, C. A.,Ozenberger, B. A.,Welch, J. S.,Link,...> ;Nat. Med.. 2014 Oct 20
• Clonal evolution revealed by whole genome sequencing in a case of primary myelofibrosis transformed to secondary acute myeloid leukemia.
  Engle, E. K.,Fisher, D. A.,Miller, C. A.,McLellan, M. D.,Fulton, R. S.,Moore, D. M.,Wilson, R. K.,Ley, T. J.,Oh, S. T.> ;Leukemia. 2014 Sep 26
• Clonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing.
  Hughes, A. E.,Magrini, V.,Demeter, R.,Miller, C. A.,Fulton, R.,Fulton, L. L.,Eades, W. C.,Elliott, K.,Heath, S.,Westervelt, P.,Ding, L.,Conrad, D. F.,White, B. S.,Shao...> ;PLoS Genet.. 2014 Jul 11
• The R882H DNMT3A Mutation Associated with AML Dominantly Inhibits Wild-Type DNMT3A by Blocking Its Ability to Form Active Tetramers.
  Russler-Germain, D. A.,Spencer, D. H.,Young, M. A.,Lamprecht, T. L.,Miller, C. A.,Fulton, R.,Meyer, M. R.,Erdmann-Gilmore, P.,Townsend, R. R.,Wilson, R. K.,Ley, T. J.> ;Cancer Cell. 2014 Mar 25
• Functional heterogeneity of genetically defined subclones in acute myeloid leukemia.
  Klco, J. M.,Spencer, D. H.,Miller, C. A.,Griffith, M.,Lamprecht, T. L.,O'Laughlin, M.,Fronick, C.,Magrini, V.,Demeter, R. T.,Fulton, R. S.,Eades, W. C.,Link, D. C.,Gra...> ;Cancer Cell. 2014 Mar 13
• ClearCode34: A Prognostic Risk Predictor for Localized Clear Cell Renal Cell Carcinoma.
  Brooks, S. A.,Brannon, A. R.,Parker, J. S.,Fisher, J. C.,Sen, O.,Kattan, M. W.,Hakimi, A. A.,Hsieh, J. J.,Choueiri, T. K.,Tamboli, P.,Maranchie, J. K.,Hinds, P.,Miller...> ;Eur. Urol.. 2014 Mar 13
• Integrated analysis of germline and somatic variants in ovarian cancer.
  Kanchi, K. L.,Johnson, K. J.,Lu, C.,McLellan, M. D.,Leiserson, M. D.,Wendl, M. C.,Zhang, Q.,Koboldt, D. C.,Xie, M.,Kandoth, C.,McMichael, J. F.,Wyczalkowski, M. A.,Lar...> ;Nat Commun. 2014 Jan 23
• DGIdb: mining the druggable genome.
  Griffith, M.,Griffith, O. L.,Coffman, A. C.,Weible, J. V.,McMichael, J. F.,Spies, N. C.,Koval, J.,Das, I.,Callaway, M. B.,Eldred, J. M.,Miller, C. A.,Subramanian, J.,G...> ;Nat. Methods. 2013 Oct 15
• 73 citations
  Molecular Basis of 9G4 B Cell Autoreactivity in Human Systemic Lupus Erythematosus
  Christopher T. Richardson, Asiya Seema Chida, Diana G Adlowitz, Lin Silver, Erin E. Fox, Scott A. Jenks, Elise M. Palmer, Youliang Wang, Jamie Heimburg-Molinaro, Quan ...> ;Journal of Immunology. 2013 Nov 15
• Mutational landscape and significance across 12 major cancer types.
  Kandoth, C.,McLellan, M. D.,Vandin, F.,Ye, K.,Niu, B.,Lu, C.,Xie, M.,Zhang, Q.,McMichael, J. F.,Wyczalkowski, M. A.,Leiserson, M. D.,Miller, C. A.,Welch, J. S.,Walter,...> ;Nature. 2013 Oct 18
• The Cancer Genome Atlas Pan-Cancer analysis project.
  Chang, K.,Creighton, C. J.,Davis, C.,Donehower, L.,Drummond, J.,Wheeler, D.,Ally, A.,Balasundaram, M.,Birol, I.,Butterfield, Y. S.,Chu, A.,Chuah, E.,Chun, H. J.,Dhalla...> ;Nat. Genet.. 2013 Sep 26
• 10 citations
  Protein kinase Cβ is required for lupus development in Sle mice.
  David Oleksyn, Mary Pulvino, Jiyong Zhao, Ravi Misra, Aram Vosoughi, Scott A. Jenks, Christopher M. Tipton, Frances E. Lund, George Schwartz, Bruce Goldman, Chandra Mo...> ;Arthritis and Rheumatism. 2013 Apr 1
• Clonal diversity of recurrently mutated genes in myelodysplastic syndromes.
  Walter, M. J.,Shen, D.,Shao, J.,Ding, L.,White, B. S.,Kandoth, C.,Miller, C. A.,Niu, B.,McLellan, M. D.,Dees, N. D.,Fulton, R.,Elliot, K.,Heath, S.,Grillot, M.,Westerv...> ;Leukemia. 2013 Jun
• Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma.
  Gutmann, D. H.,McLellan, M. D.,Hussain, I.,Wallis, J. W.,Fulton, L. L.,Fulton, R. S.,Magrini, V.,Demeter, R.,Wylie, T.,Kandoth, C.,Leonard, J. R.,Guha, A.,Miller, C. A...> ;Genome Res. 2013 Mar
• 75 citations
  Two Major Autoantibody Clusters in Systemic Lupus Erythematosus
  Kathryn H. Ching, Peter D. Burbelo, Christopher M. Tipton, Chungwen Wei, Michelle Petri, Ignacio Sanz, Michael J. Iadarola> ;Plos One. 2012 Feb 21
• Genetic heterogeneity of induced pluripotent stem cells: results from 24 clones derived from a single C57BL/6 mouse.
  Li, C.,Klco, J. M.,Helton, N. M.,George, D. R.,Mudd, J. L.,Miller, C. A.,Lu, C.,Fulton, R.,O'Laughlin, M.,Fronick, C.,Wilson, R. K.,Ley, T. J.> ;PLoS ONE. 2015 Mar 24
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