ChristopherRWeberMDPhD

PubMed

• Computational Models of Claudin Assembly in Tight Junctions and Strand Properties.
  Sarah McGuinness, Samaneh Sajjadi, Fatemeh Khalili-Araghi, Christopher R Weber> ;International Journal of Molecular Sciences. 2024 Mar 16
• A Genomic Link From Heart Failure to Atrial Fibrillation Risk: FOG2 Modulates a TBX5/GATA4-Dependent Atrial Gene Regulatory Network.
  Michael T Broman, Rangarajan D Nadadur, Carlos Perez-Cervantes, Ozanna Burnicka-Turek, Sonja Lazarevic, Anna Gams, Brigitte Laforest, Jeffrey D Steimle, Sabrina Iddir,...> ;Circulation. 2024 Apr 9
• ATAT: Automated Tissue Alignment and Traversal in Spatial Transcriptomics with Self-Supervised Learning.
  Song, S., Mohsin, E., Zhang, R., Kuznetsov, A., Shen, L., Grossman, R., Khan, A., Weber, C.> ;Biorxiv. 2023 Dec 10
• Potential Dietary and Therapeutic Strategies Involving Indole-3-Carbinole in Preclinical Models of Intestinal Inflammation.
  Aisha Qazi, Shane Comiskey, Nathan Calzadilla, Fatimah Amin, Anchal Sharma, Ei Khin, Nathaniel Holton, Christopher R Weber, Seema Saksena, Anoop Kumar, Waddah A Alrefa...> ;Nutrients. 2023 Nov 30
• 3 citations
  Epithelial IFNγ signalling and compartmentalized antigen presentation orchestrate gut immunity.
  Ankit Malik, Deepika Sharma, Raúl Aguirre-Gamboa, Shaina McGrath, Sarah Zabala, Christopher Weber, Bana Jabri> ;Nature. 2023 Nov 1
• 1 citations
  Multiomic analysis reveals cellular and epigenetic plasticity in intestinal pouches of ulcerative colitis patients.
  Zhao, Y., Zhou, R., Xie, B., Liu, C., Kalski, M., Cham, C., Koval, J., Weber, C., Rubin, D., Sogin, M., Crosson, S., Huang, J., Fiebig, A., Dalal, S., Chang, E., Basu,...> ;Medrxiv. 2023 Nov 13
• Ozanimod-Exposed Patients with Ulcerative Colitis Undergoing Total Colectomy Exhibit Unique Lymph Node Histologic Changes.
  Nathaniel A Cohen, Christopher R Weber, Jason X Cheng, David Choi, Nicole M Garcia, Natalie K Choi, David T Rubin> ;Journal of Crohn's & Colitis. 2023 Oct 25
• 1 citations
  A novel triptolide analog downregulates NF-κB and induces mitochondrial apoptosis pathways in human pancreatic cancer.
  Qiaomu Tian, Peng Zhang, Yihan Wang, Youhui Si, Dengping Yin, Christopher R Weber, Melissa L Fishel, Karen E Pollok, Bo Qiu, Fei Xiao, Anita S Chong> ;Elife. 2023 Oct 25
• CD4T Cell Responses toAre a Double-Edged Sword.
  Lykins, J. D., Kamal El Bissati, Paulette A Krishack, Ying Zhou, Christopher R Weber, Joseph Lykins, Dragana Jankovic, Karen L Edelblum, Laura Fraczek, Harshita Grover...> ;Vaccines. 2023 Sep 14
• 4 citations
  Antigen-driven colonic inflammation is associated with development of dysplasia in primary sclerosing cholangitis.
  Dustin G Shaw, Raúl Aguirre-Gamboa, Marcos C Vieira, Saideep Gona, Nicholas DiNardi, Anni Wang, Anne Dumaine, Jody Gelderloos-Arends, Zachary M Earley, Katherine R Mec...> ;Nature Medicine. 2023 Jun 1
• 7 citations
  Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis.
  Juan J Apiz Saab, Lindsey N Dzierozynski, Patrick B Jonker, Roya AminiTabrizi, Hardik Shah, Rosa Elena Menjivar, Andrew J Scott, Zeribe C Nwosu, Zhou Zhu, Riona N Chen...> ;Elife. 2023 May 31
• 1 citations
  Pathways Related to Colon Inflammation Are Associated with Colorectal Carcinoma: A Transcriptome- and Methylome-Wide Study.
  Muhammad G Kibriya, Farzana Jasmine, Joel Pekow, Aaron Munoz, Christopher Weber, Maruf Raza, Mohammed Kamal, Habibul Ahsan, Marc Bissonnette> ;Cancers. 2023 May 26
• 1 citations
  Inflammation in the proximal colon is a risk factor for the development of colorectal neoplasia in inflammatory bowel disease patients with primary sclerosing cholangi...
  Dustin Shaw, Zifeng Deng, Nicholas Dinardi, Natalie Fillman, Shivani Khanna, Noa Krugliak Cleveland, Atsushi Sakuraba, Christopher R Weber, Russell D Cohen, Sushila Da...> ;Therapeutic Advances in Gastroenterology. 2023 Jan 1
• 9 citations
  Molecular mechanism of claudin-15 strand flexibility: A computational study.
  Shadi Fuladi, Sarah McGuinness, Le Shen, Christopher R Weber, Fatemeh Khalili-Araghi> ;The Journal of General Physiology. 2022 Dec 5
• 12 citations
  AL101, a gamma-secretase inhibitor, has potent antitumor activity against adenoid cystic carcinoma with activated NOTCH signaling.
  Renata Ferrarotto, Vasudha Mishra, Elad Herz, Adar Yaacov, Oz Solomon, Rami Rauch, Adi Mondshine, Maria Motin, Tal Leibovich-Rivkin, Matti Davis, Joel Kaye, Christophe...> ;Cell Death & Disease. 2022 Aug 5
• 1 citations
  Epigenetic Dysregulation of 5-hydroxymethylcytosine in Well-Differentiated Pancreatic Neuroendocrine Tumors.
  Aarti E Sharma, Andrea D Olivas, Megan Parilla, Lindsay Yassan, Hanlin Wang, Sharon S. Zhang, Christopher R. Weber, Xavier M. Keutgen, John Hart, Thomas Krausz, Namrat...> ;Applied Immunohistochemistry & Molecular Morphology. 2021 Oct 27
• 17 citations
  T cell protein tyrosine phosphatase protects intestinal barrier function by restricting epithelial tight junction remodeling
  Ronald R. Marchelletta, Moorthy Krishnan, Marianne R. Spalinger, Taylaur W. Placone, Rocio Alvarez, Anica Sayoc-Becerra, Vinicius Canale, Ali Shawki, Young Su Park, Lu...> ;The Journal of Clinical Investigation. 2021 Sep 1
• 2 citations
  Transcriptional factors in calcium mishandling and atrial fibrillation development.
  Wenli Dai, Sneha Kesaraju, Christopher R. Weber> ;Pflugers Archiv. 2021 May 18
• 11 citations
  Histologic changes caused by injection of a novel submucosal lifting agent for endoscopic resection in GI lesions
  Andrea D Olivas, Namrata Setia, Christopher R. Weber, Shu-Yuan Xiao, Edward Villa, Christopher G. Chapman, Uzma D. Siddiqui, Irving Waxman, John Hart, Lindsay Alpert> ;Gastrointestinal Endoscopy. 2021 Feb 1
• Objective Visual Analog Scale for Biopsy Diagnosis of Helicobacter pylori Infection in Clinical Practice.
  Katherine E. Boylan, Shruti Patrey, Phillip McMullen, Vera Tesic, Christopher R. Weber, John Hart, Namrata Setia> ;The American Journal of Surgical Pathology. 2021 Jan 29
• 22 citations
  Cumulative Histologic Inflammation Predicts Colorectal Neoplasia in Ulcerative Colitis: A Validation Study
  Olivia V. Yvellez, Victoria Rai, Philip H. Sossenheimer, John Hart, Jerrold R. Turner, Christopher R. Weber, Katia El Jurdi, David T. Rubin> ;Inflammatory Bowel Diseases. 2021 Jan 19
• 134 citations
  Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids
  Brooke Schuster, Michael Junkin, Sara Saheb Kashaf, Isabel Romero-Calvo, Kori Kirby, Jonathan Matthews, Christopher R. Weber, Andrey Rzhetsky, Kevin P. White, Savaş Tay> ;Nature Communications. 2020 Oct 19
• 24 citations
  Serum Serotonin Differentiates Between Disease Activity States in Crohn's Patients.
  Christopher R. Manzella, Dulari Jayawardena, Wilfredo Pagani, Ye Li, Waddah A. Alrefai, Jessica Bauer, Barbara Jung, Christopher R. Weber, Ravinder K. Gill> ;Inflammatory Bowel Diseases. 2020 Aug 26
• 12 citations
  ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction.
  Wenli Dai, Rangarajan D. Nadadur, Jaclyn A. Brennan, Heather L. Smith, Kaitlyn M Shen, Margaret Gadek, Brigitte Laforest, Mingyi Wang, Joanna Gemel, Ye Li, Jing Zhang,...> ;Circulation Research. 2020 Jul 3
• 15 citations
  Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites
  Martin J. McPhillie, Ying Zhou, Mark Hickman, James Gordon, Christopher R. Weber, Qigui Li, Patty J. Lee, Kangsa Amporndanai, Rachel M. Johnson, Heather Darby, Stuart ...> ;Frontiers in Cellular and Infection Microbiology. 2020 Jun 9
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