ClarkDouglasWitherspoonMD

PubMed

• 1 citations
  Intravitreal injection of a rationally designed AAV capsid library in non-human primate identifies variants with enhanced retinal transduction and neutralizing antibod...
  Patrick C Kellish, Damien Marsic, Sean M Crosson, Shreyasi Choudhury, Miranda L Scalabrino, Christianne E Strang, Julie Hill, K Tyler McCullough, James J Peterson, Die...> ;Molecular Therapy. 2023 Dec 6
• 18 citations
  Lifecycles of Individual Subretinal Drusenoid Deposits and Evolution of Outer Retinal Atrophy in Age-Related Macular Degeneration
  Yuhua Zhang, Xiaolin Wang, Srinivas R. Sadda, Mark E. Clark, C. Douglas Witherspoon, Richard F. Spaide, Cynthia Owsley, Christine A. Curcio> ;Ophthalmology. Retina. 2020 Mar 1
• 23 citations
  SubILM Injection of AAV for Gene Delivery to the Retina.
  Paul D. Gamlin, John J. Alexander, Sanford L. Boye, C. Douglas Witherspoon, Shannon E. Boye> ;Methods in Molecular Biology. 2019 Jan 1
• 57 citations
  Somatic Gene Editing of GUCY2D by AAV-CRISPR/Cas9 Alters Retinal Structure and Function in Mouse and Macaque
  K. Tyler McCullough, Sanford L. Boye, Diego Fajardo, Kaitlyn R. Calabro, Jim Peterson, Christianne E. Strang, Dibyendu Chakraborty, Sebastian Gloskowski, Scott Haskett...> ;Human Gene Therapy. 2019 May 15
• 52 citations
  Highly Efficient Delivery of Adeno-Associated Viral Vectors to the Primate Retina
  E BoyeShannon, J AlexanderJohn, WitherspoonC. Douglas, L BoyeSanford, J PetersonJames, E ClarkMark, J SandeferKristen, A GirkinChris, W HauswirthWilliam, D GamlinPaul> ;Human Gene Therapy. 2016 Aug 1
• 18 citations
  DYNAMISM OF DOT SUBRETINAL DRUSENOID DEPOSITS IN AGE-RELATED MACULAR DEGENERATION DEMONSTRATED WITH ADAPTIVE OPTICS IMAGING.
  Yuhua Zhang, Xiaolin Wang, Pooja Godara, Tianjiao Zhang, Mark E. Clark, C. Douglas Witherspoon, Richard F. Spaide, Cynthia Owsley, Christine A. Curcio> ;Retina. 2018 Jan 1
• 51 citations
  Optimization of Retinal Gene Therapy for X-Linked Retinitis Pigmentosa Due to RPGR Mutations.
  William A. Beltran, Artur V. Cideciyan, Shannon E. Boye, Guo-jie Ye, Simone Iwabe, Valerie L. Dufour, Luis Felipe Marinho, Malgorzata Swider, Mychajlo S. Kosyk, Jin Sh...> ;Molecular Therapy. 2017 Aug 2
• 6 citations
  Novel Methodology for Creating Macaque Retinas with Sortable Photoreceptors and Ganglion Cells.
  Shreyasi Choudhury, Christianne E. Strang, John J. Alexander, Miranda L. Scalabrino, Julie Lynch Hill, Daniel T. Kasuga, C. Douglas Witherspoon, Sanford L. Boye, Paul ...> ;Frontiers in Neuroscience. 2016 Dec 1
• 75 citations
  Patients’ Adherence to Recommended Follow-up Eye Care After Diabetic Retinopathy Screening in a Publicly Funded County Clinic and Factors Associated With Follow-up Eye...
  Zachary Keenum, Gerald McGwin, C. Douglas Witherspoon, Julia A. Haller, Mark E. Clark, Cynthia Owsley> ;JAMA Ophthalmology. 2016 Nov 1
• 3 citations
  Ocular bartonellosis in transplant recipients: two case reports and review of the literature.
  Rachael A Lee, Manoj Ray, D.T. Kasuga, Vineeta Kumar, C.D. Witherspoon, John W. Baddley> ;Transplant Infectious Disease. 2015 Oct 1
• 164 citations
  Delayed Rod-Mediated Dark Adaptation Is a Functional Biomarker for Incident Early Age-Related Macular Degeneration.
  Cynthia Owsley, Gerald McGwin, Mark E. Clark, Gregory R. Jackson, Michael A. Callahan, C. Douglas Witherspoon, Christine A. Curcio> ;Ophthalmology. 2016 Feb 1
• 17 citations
  Feasibility and efficacy of diabetic retinopathy screening among youth with diabetes in a pediatric endocrinology clinic: a cross-sectional study.
  Jeffrey Lynn Tapley, Gerald McGwin, Ambika P. Ashraf, Paul A. MacLennan, Koula Callahan, Karen Searcey, C. Douglas Witherspoon, Jinan B. Saaddine, Cynthia Owsley> ;Diabetology & Metabolic Syndrome. 2015 Jun 24
• 78 citations
  Photoreceptor Perturbation Around Subretinal Drusenoid Deposits as Revealed by Adaptive Optics Scanning Laser Ophthalmoscopy
  Yuhua Zhang, Xiaolin Wang, Ernesto Blanco Rivero, Mark E. Clark, Witherspoon Cd, Richard F. Spaide, Christopher A. Girkin, Cynthia Owsley, Christine A. Curcio> ;American Journal of Ophthalmology. 2014 Sep 1
• 58 citations
  Associations Between Abnormal Rod-Mediated Dark Adaptation and Health and Functioning in Older Adults With Normal Macular Health
  Cynthia Owsley, Carrie Huisingh, Gregory R. Jackson, Christine A. Curcio, Alexander J. Szalai, Nassrin Dashti, Mark E. Clark, Kia Rookard, Mark A. McCrory, Tyler T. Wr...> ;Investigative Ophthalmology & Visual Science. 2014 May 22
• 42 citations
  Myofibroblast and extracellular matrix origins in proliferative vitreoretinopathy
  Richard M. Feist, Jeffery L. King, Robert Morris, C. Douglas Witherspoon, Clyde Guidry> ;Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. 2014 Feb 1
• 84 citations
  The human rhodopsin kinase promoter in an AAV5 vector confers rod- and cone-specific expression in the primate retina.
  Shannon E. Boye, John J. Alexander, Sanford L. Boye, Witherspoon Cd, Kristen J. Sandefer, Thomas J. Conlon, Kirsten E. Erger, Jingfen Sun, Renee C. Ryals, Vince A. Chi...> ;Human Gene Therapy. 2012 Jul 30
• 13 citations
  Intraoperative retinal detachment prophylaxis in vitrectomy for retained cataract fragments.
  Robert Morris, Jeffrey L. Shere, C. Douglas Witherspoon, Zachary K. Segal, Linda Tehranchi, Ferenc Kuhn, Mathew R Sapp> ;Journal of Cataract and Refractive Surgery. 2009 Mar 1
• 1 citations
  Acute posterior multifocal placoid pigment epitheliopathy and thalamic infarction.
  Jacob J. Yunker, Edgar L. Ready, Charles L. Tucker, Robert Morris, C. Douglas Witherspoon> ;Retinal Cases & Brief Reports. 2008 Jan 1
• 45 citations
  Serious fireworks-related eye injuries.
  Ferenc Kuhn, Robert Morris, C. Douglas Witherspoon, Lo Retta Mann, Viktória Mester, László Módis, András Berta, William H Bearden> ;Ophthalmic Epidemiology. 2000 Jun 1
• Anti-TMA immunity in mice. III. Induction of L-tyrosine-p-azophenyltrimethylammonium (tyr(TMA)) specific helper T cells by the monovalent antigen or idiotypic antisera.
  Alevy, Y. G., Witherspoon, C., Bellone, C. J.> ;J Immunol. 1981 Jun
• 346 citations
  The Ocular Trauma Score (OTS).
  Ferenc Kuhn, Richard Maisiak, LoRetta Mann, Viktória Mester, Robert Morris, C. Douglas Witherspoon> ;Ophthalmology Clinics of North America. 2002 Jun 1
• 21 citations
  Epidemiology and socioeconomics.
  Ferenc Kuhn, Robert Morris, Viktória Mester, C. Douglas Witherspoon, LoRetta Mann, Richard Maisiak> ;Ophthalmology Clinics of North America. 2002 Jun 1
• 196 citations
  Birmingham Eye Trauma Terminology (BETT): terminology and classification of mechanical eye injuries
  Ferenc Kuhn, Robert Morris, C. Douglas Witherspoon> ;Ophthalmology Clinics of North America. 2002 Jun 1
• 159 citations
  Epidemiology of blinding trauma in the United States Eye Injury Registry.
  Ferenc Kuhn, Robert Morris, C. Douglas Witherspoon, LoRetta Mann> ;Ophthalmic Epidemiology. 2006 Jun 1
• Removal of epimacular proliferation (EMP) in eyes.
  Morris, R., Scharper, P. H., Fletcher, D. C., Witherspoon, C. D., Kuhn, F., Harrill, M.> ;Retina. 2006 May 01
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