CliffordMitsuoTakemotoMD

PubMed

• Promoting penicillin allergy de-labeling for children attending a hematology clinic.
  Patricia Barker, Delia Charest Carias, Timothy Jacobs, Philip Carpiniello, Jay Lieberman, Clifford Takemoto, Elisabeth Adderson> ;Pediatric Blood & Cancer. 2024 Apr 28
• Empirically derived profiles of neurocognitive functioning in youth and young adults with sickle cell disease.
  Vinkrya Ellison, Kristoffer S Berlin, Jennifer Longoria, Brian Potter, Darcy Raches, Andrew M Heitzer, Jane S Hankins, Clifford Takemoto> ;Journal of Pediatric Psychology. 2024 Apr 16
• 1 citations
  Where have all the platelets gone? HIT, DIC, or something else?
  Jesudas, R., Takemoto, C.> ;Hematology. American Society of Hematology. Education Program. 2023 Dec 8
• Catechol-O-methyltransferase gene (COMT) is associated with neurocognitive functioning in patients with sickle cell disease.
  Heitzer, A., Rashkin, S., Trpchevska, A., Longoria, J., Rampersaud, E., Olufadi, Y., Raches, D., Potter, B., Steinberg, M., King, A., Kang, G., Wang, W., Takemoto, C.,...> ;Current Research in Translational Medicine. 2023 Nov 21
• Genomic analysis of venous thrombosis in children with acute lymphoblastic leukemia from diverse ancestries.
  Yan Zheng, Wenjian Yang, Jeremie Estepp, Deqing Pei, Cheng Cheng, Clifford M Takemoto, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Mary V Relling, Seth E Karol> ;Haematologica. 2024 Jan 1
• 1 citations
  Common data model for sickle cell disease surveillance: considerations and implications.
  Matthew P Smeltzer, Sarah L Reeves, William O Cooper, Brandon K Attell, John J Strouse, Clifford M Takemoto, Julie Kanter, Krista Latta, Allison P Plaxco, Robert L Dav...> ;JAMIA Open. 2023 Jul 1
• Pediatric stroke and thrombophilia-To test or not to test?
  Clifford M Takemoto> ;Pediatric Blood & Cancer. 2023 Aug 1
• 2 citations
  COVID-19 outcomes in persons with hemophilia: results from a US-based national COVID-19 surveillance registry.
  Anjali Sharathkumar, Linder Wendt, Chris Ortman, Ragha Srinivasan, Christopher G Chute, Elizabeth Chrischilles, Clifford M Takemoto> ;Journal of Thrombosis and Haemostasis. 2024 Jan 1
• Clinical characteristics and outcomes of children with newly diagnosed acute myeloid leukemia and hyperleukocytosis managed with different cytoreductive methods.
  Georgios E Christakopoulos, Kendra N Walker, Jesse Smith, Clifford M Takemoto, Yan Zheng, Ching-Hon Pui, Raul C Ribeiro, Lei Wang, Stanley B Pounds, Jeffrey E Rubnitz,...> ;Cancer. 2023 Jun 15
• Introduction: The changing role of the pediatric hematologist/oncologist in the care of people with vascular anomalies.
  Kristen Snyder, Clifford M Takemoto> ;Pediatric Blood & Cancer. 2022 Aug 1
• 2 citations
  Associated comorbidities, healthcare utilization & mortality in hospitalized patients with haemophilia in the United States: Contemporary nationally representative est...
  Jonathan R Day, Clifford Takemoto, Anjali Sharathkumar, Sarah Makhani, Ashwin Gupta, Stephanie Bitner, Cassandra D Josephson, Evan M Bloch, Aaron A R Tobian, Lakshmana...> ;Haemophilia. 2022 Jul 1
• 11 citations
  Current and future treatment approaches for Barth syndrome.
  Reid C. Thompson, John L. Jefferies, Suya Wang, William T. Pu, Clifford Takemoto, Brittany Hornby, Andrea Heyman, Michael T. Chin, Hilary J. Vernon> ;Journal of Inherited Metabolic Disease. 2021 Oct 29
• 8 citations
  CPX-351 Induces Remission in Newly Diagnosed Pediatric Secondary Myeloid Malignancies.
  Yixin Hu, Kenneth J. Caldwell, Mihaela Onciu, Sara M. Federico, Sara Lewis, Shaohua Lei, Jinghui Zhang, Kim E. Nichols, Clifford Takemoto, Brandon M. Triplett, Jason E...> ;Blood Advances. 2021 Oct 28
• 5 citations
  Incorporating G6PD genotyping to identify patients with G6PD deficiency.
  Sarah A. Morris, Kristine R. Crews, Randall T. Hayden, Clifford M. Takemoto, Wenjian Yang, Donald K. Baker, Ulrich Broeckel, Mary V. Relling, Cyrine E. Haidar> ;Pharmacogenetics and Genomics. 2021 Oct 22
• 17 citations
  How we approach thrombosis risk in children with COVID-19 infection and MIS-C.
  Anjali Sharathkumar, E. Vincent S. Faustino, Clifford Takemoto> ;Pediatric Blood & Cancer. 2021 May 6
• 20 citations
  Effect of Poloxamer 188 vs Placebo on Painful Vaso-Occlusive Episodes in Children and Adults With Sickle Cell Disease: A Randomized Clinical Trial.
  James F. Casella, Bruce A. Barton, Julie Kanter, L. Vandy Black, Suvankar Majumdar, Adlette Inati, Yasser Wali, Richard A. Drachtman, Miguel R. Abboud, Yurdanur Kilinç...> ;JAMA. 2021 Apr 20
• Reduced intensity chemotherapy with tyrosine kinase inhibitor and blinatumomab in a pediatric patient with Philadelphia chromosome-positive ALL and mechanical heart va...
  Richa Sharma, Clifford Takemoto, Benjamin Waller, Ashley Holland, Ching-Hon Pui, Hiroto Inaba> ;Pediatric Blood & Cancer. 2021 Jan 28
• 14 citations
  Kaposiform lymphangiomatosis treated with multimodal therapy improves coagulopathy and reduces blood angiopoietin-2 levels
  Janet L. Crane, Jackie Manfredo, Elisa Boscolo, Mara Coyan, Clifford Takemoto, Maxim Itkin, Denise M. Adams, Timothy D. Le Cras> ;Pediatric Blood & Cancer. 2020 Jul 7
• 7 citations
  Correlates of successful transition in young adults with sickle cell disease.
  Emily Jacobs, Olivia Gordon, Diane Weiss, Kim Winship, James F. Casella, John J. Strouse, Clifford Takemoto> ;Pediatric Blood & Cancer. 2019 Dec 1
• 11 citations
  Factors associated with red blood cell, platelet, and plasma transfusions among inpatient hospitalizations: a nationally representative study in the United States
  Ruchika Goel, Eshan U. Patel, Jodie L. White, Meera Chappidi, Paul M. Ness, Melissa M. Cushing, Clifford M. Takemoto, Beth H. Shaz, Steven M. Frank, Aaron A.R. Tobian> ;Transfusion. 2019 Feb 1
• 20 citations
  Platelet transfusion practices in immune thrombocytopenia related hospitalizations.
  Ruchika Goel, Saurav Chopra, Aaron A.R. Tobian, Paul M. Ness, Steven M. Frank, Melissa M. Cushing, Ljiljana V. Vasovic, Shipra Kaicker, Clifford M. Takemoto, Cassandra...> ;Transfusion. 2019 Jan 1
• 6 citations
  Challenges in the management of the transgender patient with sickle cell disease.
  Jocelyn Ronda, Anne Nord, Renata Arrington-Sanders, Rakhi P. Naik, Clifford M. Takemoto, Jacquelyn L. Baskin, Sophie Lanzkron, Lydia H. Pecker> ;American Journal of Hematology. 2018 Nov 1
• 3 citations
  A novel diagnostic algorithm for heparin-induced thrombocytopenia.
  Gang Zheng, Michael B. Streiff, Derek B. Allison, Clifford M. Takemoto, Kevan J. Salimian, P. Morris, Jayesh Jani, R. McCord, Thomas S. Kickler> ;International Journal of Laboratory Hematology. 2018 Oct 1
• 4 citations
  Diagnosis of congenital and acquired focal lesions in the neck, abdomen, and pelvis with contrast-enhanced ultrasound: a pictorial essay
  Matthew A. Thimm, Daniel Rhee, Clifford M. Takemoto, Wikrom Karnsakul, Carmen Cuffari, Anthony L. Guerrerio, Alejandro Garcia, John P. Gearhart, Thierry A.G.M. Huisman...> ;European Journal of Pediatrics. 2018 Jul 3
• 1 citations
  The Clinical Utility of the Heparin Neutralization Assay in the Diagnosis of Heparin-Induced Thrombocytopenia
  Gang Zheng, Michael B. Streiff, Clifford M. Takemoto, Jennifer Bynum, Elise Gelwan, Jayesh Jani, Danielle Judge, Thomas S. Kickler> ;Clinical and Applied Thrombosis/hemostasis. 2018 Jul 1
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Journal Articles

• Association of Perioperative Red Blood Cell Transfusions with Venous Thromboembolism in a North American Registry  
  Ruchika Goel, Beth Shaz, Ljiljana V Vasovic, Melissa M Cushing, Paul M Ness, Clifford M Takemoto, JAMA
• Iron Status is Associated with Asthma and Lung Function in US Women  
  Brigham,E.P., McCormack,M.C., Takemoto,C.M., and Matsui,E.C., PLoS. One, 1/1/2015
• Computerized Physician Order Entry Improves Compliance With a Manual Exchange Transfusion Protocol in the Pediatric Intensive Care Unit  
  McCrory,M.C., Strouse,J.J., Takemoto,C.M., and Easley,R.B., J. Pediatr. Hematol. Oncol, 1/1/2014
• Hospital-acquired Venous Thromboembolism in Pediatric Patients: Incidence and Clinical Characteristics  
  Takemoto,C.M., Soji,S., Desai,K., Bharaj,R., Khanna,A., McFarland,S., Klaus,S., Irshad,A., Goldenberg,N., Strouse,J., Streiff,M.B., J. Pediatrics, 1/1/2014
• Von Willebrand Disease  
  Cooper S, Takemoto C., Pediatr Rev, 1/1/2014
• Development of a New Risk Score for Hospital-Associated Venous Thromboembolism in Noncritically Ill Children: Findings from a Large Single-Institutional Case-Control S...  
  Atchison CM, Arlikar S, Amankwah E, Ayala I, Barrett L, Branchford BR, Streiff M, Takemoto C, Goldenberg NA, J Pediatr, 1/1/2014
• Risk Factors for Hospital-associated Venous Thromboembolism in the Neonatal Intensive Care Unit  
  Amankwah EK, Atchison CM, Arlikar S, Ayala I, Barrett L, Branchford BR, Streiff M, Takemoto C, Goldenberg NA, Thromb Res, 1/1/2014
• Global microRNA Expression Is Essential for Murine Mast Cell Development in Vivo  
  Oh, S. Y., Brandal S., Kapur R., Zhu Z., Takemoto C. M., Exp.Hematol, 1/1/2014
• SHP-1 Regulation of Mast Cell Function in Allergic Inflammation and Anaphylaxis  
  Zhou,L., Oh,S.Y., Zhou,Y., Yuan,B., Wu,F., Oh,M.H., Wang,Y., Takemoto,C., Van Rooijen,N., Zheng,T., and Zhu,Z., PLoS. One, 1/1/2013
• Activated Partial Thromboplastin Time and Anti-xa Measurements in Heparin Monitoring: Biochemical Basis for Discordance  
  Takemoto,C.M., Streiff,M.B., Shermock,K.M., Kraus,P.S., Chen,J., Jani,J., and Kickler,T., Am. J. Clin. Pathol, 1/1/2013
• Venous Thromboembolism in Cystic Fibrosis  
  Takemoto,C.M., Pediatr. Pulmonol, 1/1/2012
• Genetic Evidence for Critical Roles of P38alpha Protein in Regulating Mast Cell Differentiation and Chemotaxis through Distinct Mechanisms  
  Hu,P., Carlesso,N., Xu,M., Liu,Y., Nebreda,A.R., Takemoto,C., and Kapur,R., J. Biol. Chem, 1/1/2012
• Female Factor IX Deficiency due to Maternally Inherited X-inactivation  
  Esquilin,J.M., Takemoto,C.M., and Green,N.S., Clin. Genet, 1/1/2012
• Safety and Efficacy of Catheter Directed Thrombolysis in Children with Deep Venous Thrombosis  
  Darbari,D.S., Desai,D., Arnaldez,F., Desai,K., Kallen,J., Strouse,J., Streiff,M.B., Hong,K., and Takemoto,C.M., Br. J. Haematol, 1/1/2012
• Heparin-induced Thrombocytopenia Screening and Management in Pediatric Patients  
  Takemoto,C.M. and Streiff,M.B., Hematology. Am. Soc. Hematol. Educ. Program, 1/1/2011
• KIT Signaling Regulates MITF Expression through MiRNAs in Normal and Malignant Mast Cell Proliferation  
  Lee,Y.N., Brandal,S., Noel,P., Wentzel,E., Mendell,J.T., McDevitt,M.A., Kapur,R., Carter,M., Metcalfe,D.D., and Takemoto,C.M., Blood, 1/1/2011
• The PI3K Pathway Drives the Maturation of Mast Cells via Microphthalmia Transcription Factor  
  Ma,P., Mali,R.S., Munugalavadla,V., Krishnan,S., Ramdas,B., Sims,E., Martin,H., Ghosh,J., Li,S., Chan,R.J., Krystal,G., Craig,A.W., Takemoto,C., and Kapur,R., Blood, 1/1/2011
• Balanced Interactions between Lyn, the p85alpha Regulatory Subunit of Class I(A) Phosphatidylinositol-3-kinase, and SHIP Are Essential for Mast Cell Growth and Maturation  
  Ma,P., Vemula,S., Munugalavadla,V., Chen,J., Sims,E., Borneo,J., Kondo,T., Ramdas,B., Mali,R.S., Li,S., Hashino,E., Takemoto,C., and Kapur,R., Mol. Cell Biol, 1/1/2011
• Thrombotic Disease in Critically Ill Children  
  McCrory,M.C., Brady,K.M., Takemoto,C., Tobias,J.D., and Easley,R.B., Pediatr. Crit Care Med, 1/1/2011
• PU1 Positively Regulates GATA-1 Expression in Mast Cells  
  Takemoto,C.M., Brandal,S., Jegga,A.G., Lee,Y.N., Shahlaee,A., Ying,Y., Dekoter,R., and McDevitt,M.A., J. Immunol, 1/1/2010
• Noonan Syndrome: Clinical Features, Diagnosis, and Management Guidelines  
  Romano,A.A., Allanson,J.E., Dahlgren,J., Gelb,B.D., Hall,B., Pierpont,M.E., Roberts,A.E., Robinson,W., Takemoto,C.M., and Noonan,J.A., Pediatrics, 1/1/2010
• Mast Cells--Friend or Foe?  
  Takemoto,C., J. Pediatr. Hematol. Oncol, 1/1/2010
• Severe Congenital Neutropenia Resulting from G6PC3 Deficiency with Increased Neutrophil CXCR4 Expression and Myelokathexis  
  McDermott,D.H., De Ravin,S.S., Jun,H.S., Liu,Q., Priel,D.A., Noel,P., Takemoto,C.M., Ojode,T., Paul,S.M., Dunsmore,K.P., Hilligoss,D., Marquesen,M., Ulrick,J., Kuhns,D..., Blood, 1/1/2010
• SHP-1 Deficient Mast Cells Are Hyperresponsive to Stimulation and Critical in Initiating Allergic Inflammation in the Lung  
  Zhang,L., Oh,S.Y., Wu,X., Oh,M.H., Wu,F., Schroeder,J.T., Takemoto,C.M., Zheng,T., and Zhu,Z., J. Immunol, 1/1/2010
• D-dimer for the Diagnosis of Venous Thromboembolism in Children  
  Strouse,J.J., Tamma,P., Kickler,T.S., and Takemoto,C.M., Am. J. Hematol, 1/1/2009
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Books/Book Chapters

• Oski's Pediatrics: Principles and Practice 
  Chapter: General Approaches to Coagulation 
  Casella,J.F., Takemoto,C.M.Editors: J.McMillan, C.DeAngelis, R.Feigin, and D.Jones.Lippincott Williams & Wilkins, Philadelphia2006
• Casella,J.F., Pelidis,M.A., Takemoto,C.M. 
  Chapter: General Approaches to Coagulation 
  Casella,J.F., Pelidis,M.A., Takemoto,C.M.Editors: J.McMillan, C.DeAngelis, R.Feigin, and D.Jones.Lippincott Williams & Wilkins, Philadelphia2006
• Oski's Pediatrics: Principles and Practice 
  Chapter: Disorders of Coagulation Factors 
  Casella,J.F., Takemoto,C.M., Pelidis,M.A.Editors: J.McMillan, C.DeAngelis, R.Feigin, and D.Jones.Lippincott Williams & Wilkins, Philadelphia2006

Abstracts/Posters

• Lack of Inhibitor Development in the American Thrombosis and Hemostasis Network (ATHN)-2 Factor Switching Study: Preliminary Report of Primary Outcome
  Clifford Takemoto, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Associated Co-Morbidities, Healthcare Utilization, and Mortality in Hospitalized Children and Adults with Hemophilia in the United States: Updated Nationally Represent...
  Clifford M. Takemoto, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Case Control Study Of The Performance Of Activated Partial Thromboplastin Time Versus Anti-factor Xa Activity For The Monitoring Of Therapeutic Unfractionated Heparin ...
  Trucco M, Lehmann C, Mollenkopf N, Takemoto C., 25th Annual Meeting of the American Society of Pediatric Hematology/Oncology, Miami, FL, 1/1/2012
• Risk Factors for hospital acquired VTE in Pediatric Patients
  Takemoto C., Sohi S., Desai K., Strouse J.J., McFarland S., Klaus S., Irshad A., Streiff M, 24th Annual Meeting of the American Society of Pediatric Hematology/Oncology, Baltimore MD, 1/1/2011
• Safety and Efficacy of Catheter Directed Thrombolysis in Pediatric Patients
  Takemoto C., Desai D., Desai K., Arnaldez F., Strouse J.J., Hong K., Streiff M., 24th annual meeting of the American Society of Pediatric Hematology/Oncology, Baltimore MD, 1/1/2011
• Biochemical Determinants of Anti-Xa and aPTT Discordance for UFH Monitoring
  Takemoto C, Shermock K., Kraus P., Moore D., Greene P., Thiemann D., Petty B., Miller R., Streiff M., Kickler T., XXIII Congress of the International Society of Thrombosis and Haemostasis, Kyoto Japan, 1/1/2011
• Regulation of IL-13 in Mast Cells by the Let-7 miRNA Family
  Takemoto C., Gamper C., Lee Y-N, Mendell J., Brandal S., Powell J., McDevitt M., 97th Annual Meeting of the American Association of Immunologists, Baltimore MD, 1/1/2010
• KIT Signaling Regulates MITF Expression through microRNAs in Mastocytosis and Mast Cell Proliferation
  Takemoto C., Noel P., Mendell J., Wentzel E., Carter M., Metcalfe D.D., Lee Y-N., 96th Annual Meeting of the American Association of Immunologists, Seattle WA, 1/1/2009
• PU.1 and GATA-2 Participate in a Transcriptional Hierarchy to Regulate Mast Cell Development
  Lee Y-N, Jegga A, Brandal S, Sinha A, Gowrisankar S, DeKoter R, Yu W, McDevitt M and Takemoto C., Keystone Meeting, Mast Cells, Basophils, and IgE: Host Defense and Disease, Copper Mountain, Colorado, 1/1/2007
• Kit Signaling Regulated MITF Expression in Mastocytosis
  Lee Y-N, Noel P, Shahlaee A, Carter M, Kapur R, Wayne A, Metcalfe DD, and Takemoto C., 48th Annual Meeting of the American Society of Hematology, Orlando Florida, 1/1/2006
• Transcriptional Regulation of a Distinct GATA-1 Isoform during Selection of the Mast and Erythroid Lineages
  Takemoto C.M., Shahlaee A., Ye Y., Zeller K.I., Zablocki D. Huynh J., Huang S., DeKoter R.P., Jegga A.G., Aronow B.J., Dang C.V., and McDevitt M.A., 48th Annual Meeting of the American Society of Hematology, San Diego California, 1/1/2004
• Distinct Biological Functions of Mitf Isoforms in Mast Cell Development
  Shahlaee A., and Takemoto C.M., Keystone Meeting, Mast Cells in Physiology, Host Defense and Disease: Beyond IgE, Taos New Mexico, 1/1/2004
• Transcription Factor Networks That Regulate Mast Cell Development
  Shahlaee A., and Takemoto C.M., 47th Annual Meeting of the American Society of Hematology, San Diego California, 1/1/2003
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Lectures

• Diagnosis of Hemophilia A and B 
  Belize City, Belize - 1/25/2001
• von Willebrand Disease-Diagnosis and Treatment 
  Belize City, Belize - 1/25/2001
• Transcriptional Networks Regulating the Mast Lineage 
  Philadelphia, PA - 1/21/2006
• Mast Cell in Normal Development and Disease 
  Cincinnati Children's Hospital Medical Center, Cincinnati, OH - 1/26/2006
• PU.1 and GATA Factor Inter-regulation in Mast Cell Differentiation 
  Annapolis MD - 1/13/2007
• Noonan Syndrome and Hematology-What You Need to Know 
  Towson, MD, 2007; Boca Raton, FL, 2008 - 1/17/2007
• Noonan Syndrome and Issues in Hematology 
  Newark, NJ - 1/18/2008
• Mast Cell Transcriptional Networks in Normal Development and Disease 
  Johns Hopkins Bayview Medical Center, Baltimore, MD - 1/7./2008
• Iron Deficiency 
  St. Agnes Hospital, Baltimore MD - 1/13/2009
• Regulation of IL-13 in Mast Cells by the Let-7 miRNA Family 
  Baltimore MD - 1/7./2010
• Invited Discussant for a case of Tachypnea and Tachycardia as Presenting Symptoms of an Unusual Complication in a Child 
  Baltimore MD - 1/21/2010
• Heparin-induced Thrombocytopenia Screening and Management in Pediatric Patients 
  San Diego CA - 1/10/2011
• VTE Prophylaxis in Pediatrics: The Johns Hopkins Children's Center Experience 
  Baltimore MD - 1/9./2012
• Surgery Trials-Yes We Can! 
  Rome Italy - 1/23/2013
• High Dose Cytoxan in Pediatrics: The Johns Hopkins Experience. 
  Texas Children's Hospital, Houston Texas - 1/26/2013
• State of the Art Heparin Monitoring 
  Washington DC. - 1/2./2013
• VTE in Pediatrics 
  Baltimore MD - 1/7./2014
• Venous Thromboembolism in Cystic Fibrosis: Prevalence, Risk & Management 
  Atlanta Georgia - 1/9./2014
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Other

• Neonatal Anticoagulation 
  Strouse, J.J, Takemoto, C.M., eNeonatal Review
  1/1/2009
• Thromboembolic Disease in the Neonate 
  Strouse, J.J, Takemoto, C.M., eNeonatal Review
  1/1/2005